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All Journal Jurnal Inovasi Teknologi Pendidikan QUANTUM: Jurnal Inovasi Pendidikan Sains Vidya Karya Journal of Islamic Pharmacy Media Kesehatan Politeknik Kesehatan Makassar JOURNAL OF CHEMISTRY AND EDUCATION (JCAE) Majalah Farmasetika Jurnal Ilmiah Agribios Journal of Mathematics Science and Computer Education Communication and Information Journal Jurnal Kebidanan : Jurnal Ilmu Kesehatan Budi Mulia Journal of Pharmaceutical and Sciences. Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Jurnal Pembaruan Kesehatan Indonesia
Leny Leny, Leny
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Pengaruh Ekstrak Daun Nanas Terhadap Pertumbuhann Candida albicans Dan Malassezia furfur Dalam Bentuk Sediaan Shampo Herbal Abadi , Hafizhatul; Khairani , Tetty Noverita; Fitri, Khairani; Diana, Vivi Eulis; Leny, Leny; Hasibuan, Amalia Juliani
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1181

Abstract

Background: Dandruff is a common scalp problem often caused by the overgrowth of fungi such as Candida albicans and Malassezia furfur. Pineapple leaves (Ananas comosus (L.) Merr.) are known to contain active antifungal compounds, such as alkaloids, flavonoids, saponins, and tannins, making them a potential active ingredient for anti-dandruff preparations. Objective: This study aimed to formulate an herbal anti-dandruff shampoo using pineapple leaf ethanol extract and to evaluate its effectiveness in inhibiting the growth of Candida albicans and Malassezia furfur. Methods: This experimental research used the disc diffusion method with PDA and SDA media to test antifungal inhibition. The shampoo preparations were formulated with varying extract concentrations (10%, 20%, 30%). The evaluation of the preparations included organoleptic tests, homogeneity, pH, foam height, viscosity, stability (cycling test), skin irritation, and hedonic tests. Results: The resulting shampoo preparation had a blackish-brown color, liquid form, and a menthol odor. Evaluation results showed the preparation was homogeneous, with pH values (5.0-5.8), foam height, and viscosity meeting the requirements. The preparation was also stable during the cycling test and did not cause irritation. The antifungal activity test showed that increasing the extract concentration increased the inhibitory power. The formula with a 30% concentration (F3) provided the greatest inhibition against Candida albicans (average 15.76 mm) and Malassezia furfur (average 15.9 mm), which is categorized as strong. Conclusion: Pineapple leaf ethanol extract was successfully formulated into an effective herbal anti-dandruff shampoo preparation, with the 30% concentration being the most optimal. It is recommended that further research investigate the antifungal activity of this extract against other types of fungi and in different dosage forms.
Co-Authors Abadi , Hafizhatul Abadi, Hafizhatul Abdul Hamid Atiek Winarti Bakti, Iriani BENNI ISKANDAR Chan, Adek Diana, Vivi Eulis Elfa, Noor Fadhlan Muchlas Abrori Faisal, Hendri Febrianti, Shabrina Adzhani Fitri, Khairani FRANSISKA, ELLA Ginting, Indra Gumilar, Roni Hanum, Widia Hasibuan, Amalia Juliani Hayati, Farida Ihsanul Hafiz Iriani*, Rilia Khairani , Tetty Noverita Mahdian Mahdian, Mahdian Masila, Rizqa Melia Sari, Melia Mintasih, Mintasih Muhammad Andry Muhammad Kusasi Mustarianti, Lila Nababan, Herbet Nasution, Meiliza Putri Ngete, Ani Florida Nita Adriana, Nita Norlaila Norlaila Novianti, Rinda Oktavia Nurjanah, Ayu Pamungkas, Barolym Tri Parham Saadi, Parham Rilia Iriani Risna Risna, Risna Rudang, Singgar Ni Rusmansyah Rusmansyah, Rusmansyah Sari, Nindy Novita Sidabutar, Santa Eni BR Simanjuntak, Heppy Taruli Sitanggang, Joanna Siti Fatimah Hanum Syahmani Syahmani Syahputri, Susi Tarigan, Jacub Tirta Anggraini Utami, Novariani Indri Wahidah Wahidah Winata, Hanafis Sastra Wiranti, Wiranti Yogo Dwi Prasetyo Yudianto, Tri Zega, Dani Elwan