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All Journal Jurnal Anestesiologi Indonesia Media Kesehatan Masyarakat Indonesia Jurnal Kedokteran Syiah Kuala Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Biomedika Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Vokasional Buletin Farmatera Jurnal Pendidikan Kimia (JPKim) GHIDZA: Jurnal Gizi dan Kesehatan Jurnal Riset Kesehatan Poltekkes Depkes Bandung Bioscientia Medicina : Journal of Biomedicine and Translational Research PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Prima Medika Sains JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Implementa Husada Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Open Access Indonesian Journal of Medical Reviews Bioscientia Medicina : Journal of Biomedicine and Translational Research Pancasakti Journal Of Public Health Science And Research Community Medicine and Education Journal Kieraha Medical Journal Jurnal Impresi Indonesia International Journal of Islamic Education, Research and Multiculturalism (IJIERM) KNOWLEDGE: Jurnal Inovasi Hasil Penelitian dan Pengembangan Abdi Cendekia: Jurnal Pengabdian Masyarakat Jurnal Ilmu Kesehatan dan Gizi
Gusbakti Rusip
Department Of Physiology, Faculty Of Medicine, Universitas Prima Indonesia, Medan, Indonesia
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Korelasi karies gigi dan status gizi pada anak usia 3-5 tahun Wibowo, Angga Arjuno; Rusip, Gusbakti; Erawati, Suci
Jurnal Prima Medika Sains Vol. 5 No. 1 (2023): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i1.3428

Abstract

Penelitian ini bertujuan untuk menganalisis hubungan karies gigi dengan status gizi. Penelitian ini merupakan jenis penelitian observasional analitik dengan desain cross-sectional. Penelitian ini dilakukan di Desa Araskabu, Kecamatan Beringin, Kabupaten Deli Serdang pada bulan Oktober 2022 hingga Desember 2022. Besar sampel pada studi ini sebanyak 70 orang.  Pengumpulan data dilakukan dengan menggunakan kuisioner serta dilakukan pemeriksaan indeks DMF-T berdasarkan WHO melalui pemeriksaan klinis pada rongga mulut menggunakan diagnostic set disposable dan pencahayaan dari headlamp. Analisis data yang digunakan dalam penelitian ini adalah analisis univariat dan bivariat (uji Chi Square). Hasil penelitian menunjukkan bahwa tidak ada kaitan antara karies gigi dengan status gizi pada anak usia 3-5 tahun (p=0,357). Namun dengan tingginya prevalensi karies gigi (61,1%) maka perlu adanya perhatian khusus untuk mengintervensi melalui pemantauan berkala, memperhatikan konsumsi makanan anak dan memberikan edukasi pada orang tua dan pihak sekolah.
The Effect of Giving Red Dragon Fruit Juice on Changes in Leukocyte Levels and Fatigue Time in Maximum Intensity Physical Exercise Rianingsih, Rika; Rusip, Gusbakti
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.5552

Abstract

Physical exercises contribute to oxidative tresses to cause fatigue and reduce the level of antioxidants in the body so that it affects physical fitness. Antioxidants are needed to neutralize free radicals and prevent damage to oxidative stress. This study aimed to determine the effect of red dragon fruit juice (Hylocereus polyrhizus) on leukocyte levels and tiring time in maximum intensity physical exercise. This research is the experimental research of the pre-test and post-test control group design. The research samples were divided into two groups, i.e. the control and treatment groups. Leukocyte levels were checked by using 2ml blood samples with hematology analyzers. Tiring time was determined by a treadmill test, in which the subject was asked to run until he/she reached maximum pulse. The minute the subject feels fatigued was documented as tiring time. This study showed significant results of leukocyte levels before and after treatment with a p-value of 0.005, tired time showed a p-value of 0.001, in which there was the lateness of tired time among the intervention group. Subjects who were given red dragon juice showed there was no increase in leukocyte levels and experienced lateness in the occurrence of tired time. That showed a better physical fitness level among the intervention group.
Antibacterial Effects of Star Fruit Extract Against Streptococcus sanguinis Purba, Member Reni; Gusbakti Rusip; Salsabilah
Community Medicine and Education Journal Vol. 5 No. 1 (2024): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v5i1.434

Abstract

Streptococus sanguinis is a pioneer bacteria that colonize the oral cavity, plays a role in plaque formation, and contributes to the development of dental caries. Plaque control is needed to inhibit the growth of microorganisms that cause caries by using herbal plants such as starfruit. The aim of the research was to determine whether or not there was an antibacterial effect of starfruit extract (Averrahoa bilimbilin).) against the bacteria Streptococus sanguinis. This research includes laboratory experiments with the sample as a pure culture of Streptococus sanguinis obtained from the Microbiology Laboratory of North Sumatra University Hospital. There were 5 treatment groups (starfruit extract concentration 6.25%, 12.5%, 25%, 50%, 75%), positive control (chlorhexidine 0.2%), and negative control (DMSO). The antibacterial effect was tested using the disc diffusion method. Then, the data was analyzed using statistical tests, one-way ANOVA, and, after this, LSD. The research results were obtained mean, and standard deviation of the diameter of the inhibition zone of star fruit extract, concentrations of 12.5%, 25%, 50%, 75%, and positive control for bacteria Streptococus sanguinis were 7.05 ± 0.192 mm, 9.38 ± 0.171 mm, 13.38 ± 0.171 mm, 14.30 ± 0.216 mm, and 14.38 ± 0.096 mm, while the concentration of star fruit extract was 6.25% and the negative control no inhibition zone was found. Test results from one-way ANOVA revealed that there was a significant antibacterial effect of star fruit extract against the bacteria Streptococus sanguinis (p≤0.05). Test results after this LSD found that the antibacterial effect of the 75% concentration extract was not significant with the positive control, and the 6.25% concentration was not significant with the negative control (p>0.05). From the research results, it can be concluded that the higher the concentration of the extract, the higher the antibacterial effect, with the most effective concentration being 75% and the MIC at a concentration of 12.5%.
The Relationship between the Level of Satisfaction of Dental Students in the Appearance of Anterior Teeth in Terms of Orthodontic Treatment at Universitas Prima Indonesia Rusip, Gusbakti; Suci Erawati; Daniel Yantonius Simamora
Community Medicine and Education Journal Vol. 5 No. 1 (2024): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v5i1.465

Abstract

One aspect of appearance that increases self-confidence among students is having an aesthetic smile. To achieve this, it is important to pay attention to the anterior teeth because the appearance of the teeth determines aesthetic appeal. If the anterior teeth experience malocclusion, this has an impact on reducing the level of self-confidence, creating difficulty interacting socially, and creating dissatisfaction with the appearance of the anterior teeth for students. To fill the gap, this study aims to further investigate the relationship between the satisfaction level of the dental education undergraduate study program in the appearance of anterior teeth in terms of orthodontic treatment at Universitas Prima Indonesia. A total of 44 respondents were students of the dental education undergraduate study program who were sampled in the study using the online survey method. This study used univariate and bivariate analysis through SPSS v.24. There is a significant relationship between fixed orthodontic treatment and the satisfaction of the appearance of the anterior teeth of UNPRI dental education undergraduate students.
Differences in Saliva pH of Users and Non-users of Fixed Orthodontic Wire in Dental Students (FKG UNPRI) Rusip, Gusbakti; Member Reni Purba; Fitri Inriani Silaban
Community Medicine and Education Journal Vol. 5 No. 1 (2024): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v5i1.505

Abstract

Fixed orthodontics corrects malocclusion, which can compromise facial aesthetics. Nevertheless, the utilization of this orthodontic apparatus presents the potential for plaque buildup stemming from the colonization of microorganisms, which may influence the pH of saliva. The purpose of the research was to compare the pH levels of the saliva of individuals who utilized fixed orthodontic wires to those who did not. The design of this survey-analytic, cross-sectional study is survey-based. Sixty-two FKG UNPRI students who satisfied the inclusion and exclusion criteria comprised the sample. We divided these students into two groups: one group utilized fixed orthodontic wires, while the other group did not. To determine the pH of saliva, submerge the pH paper tip into the saliva. If a color change occurs, modify the pH paper using a saliva pH indicator. Following the collection of all the data, an analysis of the data was conducted utilizing the Mann-Whitney statistical test. The study findings indicated that individuals who utilized fixed orthodontic wires had an average saliva pH of 6.16 ± 0.735, whereas those who did not use the devices had a saliva pH of 7.19 ± 0.543. According to the findings of the Mann-Whitney statistical test, a statistically significant distinction in saliva pH was observed between individuals who utilized fixed orthodontic wires and those who did not (p = 0.000; p<0.05). In conclusion, users of fixed orthodontic wires have, on average, a lower salivary pH than non-users.
Pemanfaatan Ekstrak Biji Labu Kuning (Cucurbita moschata) sebagai Sediaan Krim Anti-Aging Mutia, Maya Sari; Rusip, Gusbakti; Kurniawan, Gracella Verren; Sartika, Dewi; Nadia, Felanda Ahsan; Henny, Henny
Jurnal Kesehatan Vokasional Vol 9, No 4 (2024): November
Publisher : Sekolah Vokasi Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkesvo.99524

Abstract

Latar Belakang: Meningkatnya kesadaran akan pentingnya perawatan kulit berbahan alami mendorong permintaan produk anti-aging. Biji labu kuning (Cucurbita moschata) yang mengandung antioksidan seperti vitamin E, karotenoid, dan asam lemak esensial, efektif melawan radikal bebas dan memperlambat penuaan kulit, menjadikan pilihan tepat untuk krim anti-aging ramah lingkungan.Tujuan: Penelitian ini  bertujuan untuk mengetahui manfaat dari ekstrak biji Cucurbita Moschata sebagai krim anti-penuaan.Metode: Penelitian ini menggunakan metode eksperimen dengan desain Pretest-Posttest Control Group. Penelitian dilakukan di Laboratorium Farmakologi Fakultas Farmasi Universitas Sumatera Utara (Mei-Juli 2024). Sampel berupa krim anti-aging dengan ekstrak biji labu kuning, yang diuji pada lima kelompok tikus: kontrol negatif, kontrol positif, dan tiga kelompok dengan konsentrasi 4%, 8%, dan 12%. Data dianalisis menggunakan uji Wilcoxon pada SPSS untuk menilai efektivitas dosis krim terhadap tanda penuaan.Hasil: Ekstrak biji labu kuning dengan konsentrasi 4%, 8%, dan 12% terbukti efektif meningkatkan kelembapan kulit. Analisis histopatologi menunjukkan bahwa konsentrasi 12% secara signifikan meningkatkan kepadatan serat kolagen, mendukung efektivitas krim dalam mengatasi tanda-tanda penuaan.Kesimpulan: Ekstrak biji labu kuning dengan konsentrasi 4%, 8%, dan 12% efektif meningkatkan kelembapan, aktivitas antioksidan, dan densitas kolagen. Konsentrasi 12% sebagai dosis optimal yang memberikan hasil terbaik dibandingkan konsentrasi 4% dan 8%.
ROLE OF CURCUMA ZEDOARIA EXTRACT ON PLACENTAL GROWTH FACTOR (PLGF) IN DIABETIC RETINOPATHY WHITE WISTAR RATS Ong, Gabriella Fransisca; Rusip, Gusbakti; Chiuman, Linda; Sulistijanto, Eddy; Tarigan, Elviyanti
International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Vol 6 No 3 (2024)
Publisher : The Islamic Education and Multiculturalism Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47006/ijierm.v6i3.400

Abstract

Diabetic retinopathy is damage to retinal capillaries in diabetics that can cause visual impairment, ranging from mild to permanent blindness. This study aims to analyze the effect of Curcuma zedoaria (temu putih) extract on placental growth factor (PLGF) levels in white Wistar rats with diabetic retinopathy. The research design used post-test only control group, involving six groups of wistar rats with five heads each. Data were analyzed using Oneway ANOVA and t-test. The results showed that the administration of Curcuma zedoaria extract at a dose of 500 mg/kgBB had the greatest effect on reducing PLGF in diabetic retinopathy rats. For reducing blood sugar levels (KGD), a dose of 7500 mg/kgBB proved to be the most effective. However, no significant relationship was found between PLGF levels and retinal histopathology results. Most of the rats had a retinal score of 0, which means no inflammatory cells were found in the retinal layer (0 cells/visual field). There were rats with a retinal score of 1, namely rats that received doses of 250 mg/kgBB and 500 mg/kgBB. In this score, inflammation was found in the outer plexiform layer (OPL). In addition, there were rats with a retinal score of 2 at a dose of 250 mg/kgBB, which also showed the distribution of inflammation in the OPL layer. In this study, Curcuma zedoaria extract can reduce PLGF and KGD in Wistar rats with diabetic retinopathy, although its effect on improving retinal histopathology is still limited.
HUBUNGAN KONSUMSI KOPI DENGAN PENYAKIT GASTROESOPHAGEAL REFLUX DISEASE PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS PRIMA INDONESIA Dhillon, Neha Amar; Rusip, Gusbakti; Chiuman, Linda
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.32740

Abstract

Gastroesophageal reflux disease (GERD) adalah penyakit yang sering diderita di kalangan masyarakat. GERD dijelaskan sebagai naiknya asam lambung ke esofagus atau kerongkongan sehingga menyebabkan regurgitasi makanan ke esofagus. Proporsi untuk GERD pada orang dewasa sekitar 13%, Asia Selatan dan Eropa Tenggara memiliki prevalensi GERD paling banyak sekitar 25%. Prevalensi GERD di Indoensia terus mengalami peningkatan sebanayak 22,8% di Jakarta. Penyakit GERD didefinisikan oleh gejala-gejala utama seperti regurgitasi oleh cairan dan heartburn yang mengulang. GERD bisa menjadi masalah yang berat jika tidak ditangani. Banyak faktor yang dapat memicu GERD, diantara lain yaitu konsumsi makanan rendah gizi dan tinggi lemak pada mahasiswa, olahraga yang tidak memadai, sehingga berat badan naik. Salah satu faktor lainnya yang dapat menyebabkan GERD pada mahasiswa adalah konsumsi kopi yang berlebihan. Di kalangan mahasiswa, kopi sangat digemari. Mahasiswa kedokteran sering mengonsumsi kopi untuk meningkatkan produktivitas saat belajar dan kopi banyak dikonsumsi pada masa ujian. Tujuan penelitian ini untuk mengetahui hubungan konsumsi kopi dengan penyakit gastroesophageal reflux disease pada Mahasiswa Fakultas Kedokteran Universitas Prima Indonesia. Studi ini menggunakan teknik Purposive Sampling dengan sampel sebanyak 32 orang di Fakultas Kedokteran Universitas Prima Indonesia dan dianalisis dengan uji Chi-Square. Didapatkan hasil uji Fisher’s exact test pada 32 subjek adalah p = 0,032 (p<0,05) yang dapat disimpulkan terdapat perubahan yang signifikan antara konsumsi kopi dan penderita GERD pada Mahasiswa Fakultas Kedokteran Universitas Prima Indonesia.
PENGARUH PEMBERIAN EKSTRAK ANDALIMAN (ZANTHOXYLUM ACANTHOPODIUM DC) TERHADAP KADAR HIGH SENSITIVITY C REACTIVE PROTEIN (HS-CRP) TIKUS WISTAR JANTAN YANG DIINDUKSI STZSTZ Caroline S, Cecilia; Suandy, Suandy; Rusip, Gusbakti
Kieraha Medical Journal Vol 6, No 2 (2024): KIERAHA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran, Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/kmj.v6i2.9113

Abstract

Diabetes Mellitus (DM) merupakan penyakit dengan prevalensi mencapai 8,3% dari populasi dunia pada tahun 2014 dan meningkat hingga 387 juta kasus berdasarkan data International Diabetes Federation. Prevalensi diabetes melitus, sekitar 4.8% dan lebih dari 58.8% kasus diabetes melitus tidak terdiagnosis, pada masyarakat di Indonesia penyandang diabetes melitus di tahun 2030. Prevalensi diabetes melitus menjadi persoalan kesehatan yang serius, karena mengalami peningkatan jumlah penderita di setiap tahunnya.  Biaya pengobatan yang tinggi mendorong pencarian alternatif, seperti andaliman yang dianggap memiliki aktivitas antidiabetes dan antioksidan. Tujuan penelitian ini, untuk mengetahui pengaruh efektivitas ekstrak andaliman dalam menurunkan kadar gula darah, mengatasi resistensi insulin yang diukur melalui Hs-CRP, dan melindungi sel β pankreas dari kerusakan pada tikus putih yang diinduksi Streptozotocin (STZ). Penelitian ini menggunakan posttest only controlled group design, dengan Kelompok 1 normal (tanpa diberikan perlakuan), Kelompok 2 kontrol negatif (STZ 65mg/kgBB), Kelompok 3 kontrol positif (STZ 65mg/kgBB + Metformin), Kelompok 4 Perlakuan 1 (STZ 65mg/kgBB + Nanopartikel 25mg/kgBB), Kelompok 5 Perlakuan 2 (STZ 65mg/kgBB + Nanopartikel 50mg/kgBB ), Kelompok 6 Perlakuan 3 (STZ 65mg/kgBB + Nanopartikel 75mg/kgBB). Hasil penelitian berdasarkan analisa ANNOVA dengan dosis andaliman 75mg/kgBB pada kelompok 6 didapati perbedaan bermakna signifikan secara statistik p=0,005 (p0,05)
Fig Leaf (Ficus carica Linn.) Extract as a Potential Alternative Treatment for Oral Thrush Caused by Candida albicans Gusbakti Rusip; Shieny Lokanata; Vivin Lydia
Open Access Indonesian Journal of Medical Reviews Vol. 5 No. 1 (2025): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v5i1.698

Abstract

Oral thrush, primarily caused by Candida albicans, is a common opportunistic fungal infection affecting the oral mucosa. The increasing resistance of C. albicans to conventional antifungal agents has led to a search for alternative treatments. Fig leaf (Ficus carica Linn.) has been traditionally used for its medicinal properties and has shown promising antifungal activity. This study aimed to evaluate the inhibitory potential of ethanol extract of fig leaf against C. albicans in vitro. Fig leaves were collected, dried, and extracted using ethanol. The extract was then screened for its phytochemical constituents. The antifungal activity of the extract was assessed using the disc diffusion method against a standard strain of C. albicans. Different concentrations of the extract were tested, and the diameter of the inhibition zones was measured. Data were analyzed using one-way ANOVA and post hoc LSD tests. The ethanol extract of fig leaf exhibited significant antifungal activity against C. albicans. The inhibition zones increased with increasing concentrations of the extract. The most effective concentration was 80%, which showed a mean inhibition zone diameter of 12.65 ± 1.22 mm. Phytochemical screening revealed the presence of flavonoids, triterpenoids/steroids, glycosides, saponins, and tannins in the extract. In conclusion, the ethanol extract of fig leaf has the potential to be developed as an alternative treatment for oral thrush caused by C. albicans. Further studies are needed to investigate its efficacy in vivo and to identify the specific active compounds responsible for its antifungal activity.
Co-Authors Aditya Candra AMELIA EKA DAMAYANTI Anita Surya Arianti, Ara Safitri ASHIL MUHAMMAD ABDUL RASYID Aurelia, Nada Bangun, Primta Bintang Y.M Sinaga Caroline S, Cecilia Chiuman, Linda Daniel Yantonius Simamora DEWI SARTIKA Dhillon, Jessyca Manishwer Kaur Dhillon, Neha Amar Doli, Doni Dwi Astuti Manullang Edy Fachrial ELMAN BOY Erawati, Suci Esther R. D. Sitorus FAWWAZ NAUFAL RACHMADI Fiska Maya Wardhani Fitri Inriani Silaban Ginting, Astriani Natalia Br Ginting, Chrismis Novalinda Hafiz Anugrah Mursyid Halim, Susanna Harianto Bangun Henny Henny, Henny HUDDY ARTICA SINULINGGA Joanna Elvia Harefa Karolina Br Surbakti Kurniawan, Gracella Verren M. Ichwan Mangatas Silaen Mangkuanom, Adrian Saleh Manihuruk, Fani Nuryana Martina Evelyn R.H Melviana Lubis Member Reni Purba Meutia, Rena Muharraran, Firdha Mursyid, Hafiz Anugrah Mutia, Maya Sari NABILA HANA SYAQILA Nadia, Felanda Ahsan NANDA SYAVIRA Napitupulu, Olivia Des Vinca Albahana Nathasia, Ingee Ong, Gabriella Fransisca Purba, Member Reni Putra, Ananda Rahmat PUTRI SARMADANI HASIBUAN QORY AULIA DANA LUBIS Razoki Riamah, Riamah Rianingsih, Rika Robitah Asfur Rosa Paradita Dalimunthe Sagala, Agasy Gideon Admiral Salsabilah Shieny Lokanata Sinaga, Theresia Margaretha Sinurat, Ariel Oertega Suandy, Suandy Suci Erawati Sulistijanto, Eddy Susanto, Chandra Syarbaini, Siti Farah Syarifah, Anita Tambunan, Adrian Nurrachman Tambunan, Andika Zayani Tarigan, Elviyanti Tiarnida Nababan Vivin Lydia Wafi Aqilah Yafa Wibowo, Angga Arjuno Yetty Machrina Zul Alfian