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All Journal Jurnal Anestesiologi Indonesia Media Kesehatan Masyarakat Indonesia Jurnal Kedokteran Syiah Kuala Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Biomedika Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Vokasional Buletin Farmatera Jurnal Pendidikan Kimia (JPKim) GHIDZA: Jurnal Gizi dan Kesehatan Jurnal Riset Kesehatan Poltekkes Depkes Bandung Bioscientia Medicina : Journal of Biomedicine and Translational Research PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Prima Medika Sains JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Implementa Husada Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Open Access Indonesian Journal of Medical Reviews Bioscientia Medicina : Journal of Biomedicine and Translational Research Pancasakti Journal Of Public Health Science And Research Community Medicine and Education Journal Kieraha Medical Journal Jurnal Impresi Indonesia International Journal of Islamic Education, Research and Multiculturalism (IJIERM) KNOWLEDGE: Jurnal Inovasi Hasil Penelitian dan Pengembangan Abdi Cendekia: Jurnal Pengabdian Masyarakat Jurnal Ilmu Kesehatan dan Gizi
Gusbakti Rusip
Department Of Physiology, Faculty Of Medicine, Universitas Prima Indonesia, Medan, Indonesia
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HUBUNGAN AKTIVITAS FISIK TERHADAP PERUBAHAN KARDIORESPIRASI PADA MAHASISWA KEDOKTERAN UNIVERSITAS PRIMA INDONESIA Sagala, Agasy Gideon Admiral; Rusip, Gusbakti; Chiuman, Linda
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 2 (2024): AGUSTUS 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i2.31517

Abstract

Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik dengan perubahan fungsi kardiorespirasi pada mahasiswa kedokteran Universitas Prima Indonesia. Penelitian ini menggunakan pendekatan eksperimen semu dengan desain one-group pre-and post-test untuk menguji hubungan tersebut. Purposive sampling dengan rumus Federer digunakan untuk memilih sampel yang berjumlah 32 orang mahasiswa kedokteran Universitas Prima Indonesia. Queen's College Step Test digunakan untuk mengukur kebugaran kardiorespirasi dan aktivitas fisik dalam data yang dikumpulkan. Analisis data memakai SPSS versi 27 serta Uji Wilcoxon digunakan untuk analisis statistik, dengan ambang signifikansi P <0,05. Temuan penelitian menunjukkan bahwa di kalangan mahasiswa kedokteran Universitas Prima Indonesia, aktivitas fisik dan perubahan fungsi kardiorespirasi berhubungan (P=0,005). Dari tiga puluh dua orang mahasiswa kedokteran Universitas Prima Indonesia didapati Delapan orang mahasiswa kedokteran Universitas Prima Indonesia semuanya mengalami perubahan pada sistem kardiorespirasi mereka sebelum dan sesudah melakukan aktivitas fisik (4,50). Artinya Terdapat hubungan aktivitas fisik dengan perubahan fungsi kardiorespirasi pada mahasiswa kedokteran Universitas Prima Indonesia.
STUDI INTERAKSI OBAT ANTIHIPERLIPIDEMIA DI RUMAH SAKIT UMUM ROYAL PRIMA MEDAN Sinaga, Theresia Margaretha; Rusip, Gusbakti; Fachrial, Edy
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.31310

Abstract

Hiperlipidemia adalah sebuah kondisi abnormal metabolik lipid dengan indikasi kadar lipid di dalam darah mengalami kenaikan. Secara umum, hiperlipidemia sering diikuti dengan adanya penyakit lain, sehingga sering digabungkan dengan obat jenis lain dan memicu terjadinya interaksi obat. Tujuan dari pelaksanaan penelitian ini yaitu untuk  mengetahui apakah ada kejadian interaksi obat antihiperlipidemia di rumah sakit umum royal prima medan dan untuk mengidentifikasi tingkat keparahan interaksi obat antihiperlipidemia pada pasien di rumah sakit umum royal prima medan. Penelitian ini termasuk penelitian observasi(survey), jenis penelitian yang diterapkan yaitu survey analitik dan pengambilan data dilaksanakan dengan retrospeksi. Jenis analisis yang digunakan yaitu analisis data univariat dan pengolahan dilakukan secara teoritis menggunakan stokley drug interaction dan review aplikasi drugs.com. Dari 120 lembar resep yang dikaji, dapat disimpulkan bahwa karakteristik sesuai dengan jenis kelamin menunjukkan persentase tertinggi dari peresepan yaitu pasien yang berjenis kelamin perempuan sebanyak 64 pasien (53,3%). Karakteristik berdasarkan usia tertinggi 50-59 tahun (29,2%). Berdasarkan ada tidaknya interaksi yang menunjukkan persentasi tertinggi yang menggunakan lebih dari 5 obat yaitu sebanyak 56 lembar resep (58,3%). Berdasarkan penggunaan antihiperlipidemia terbanyak yaitu golongan atorvastatin sebanyak 114 resep (70%). Berdasarkan dengan tingkat keparahan interaksi obat terbanyak terjadi pada tingkat keparahan moderat yaitu sebanyak 189 kasus (84,4%).
ARTIKEL REVIEW KASUS IMPLAN GIGI: EVALUASI PROSEDUR, TANTANGAN, DAN HASIL KLINIS Halim, Susanna; Rusip, Gusbakti; Sinurat, Ariel Oertega
KNOWLEDGE: Jurnal Inovasi Hasil Penelitian dan Pengembangan Vol. 5 No. 1 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/knowledge.v5i1.5086

Abstract

The use of dental implants is increasingly recognized as a solution to replace missing teeth. This research aims to explore the selection of materials and techniques in the development of effective and biocompatible dental implants. The main focus of this study is on bioactive materials such as hydroxyapatite (HA) and calcium metaphosphate (CMP), as well as the potential of hydroxyapatite from chicken bone as an alternative coating for dental implants. Additionally, the importance of public education through religious-based counseling is also explored to enhance the acceptance of this technology. The method used in this research is a literature review and analysis of relevant research findings. The studies analyzed include those on surface modification of dental implants with bioactive materials, the potential of hydroxyapatite from chicken bone, and research on public counseling regarding dental implants from an Islamic perspective. The analysis involves comparing the findings from existing studies and drawing key conclusions from each stud.. The results of the study show that surface modification of implants with bioactive materials can enhance bone healing and the success of osseointegration. The CMP coating proves to be superior to HA in terms of resistance to delamination and particle reduction, which could lead to implant failure. Surface modification of implants with bioactive materials like CMP and HA plays a significant role in improving osseointegration and implant stability. Moreover, the use of hydroxyapatite from chicken bone as an alternative coating for implants provides a cost-effective solution and has the potential to reduce the cost of dental implant development. Surface modification of implants with bioactive materials such as HA and CMP can improve osseointegration success, with CMP showing superiority. Additionally, hydroxyapatite from chicken bone offers a cost-effective solution in the development of dental implants. ABSTRAKPenggunaan implan gigi semakin berkembang sebagai solusi untuk menggantikan gigi yang hilang. Penelitian ini bertujuan untuk mengeksplorasi pemilihan bahan dan teknik dalam pengembangan implan gigi yang efektif dan biokompatibel. Fokus utama penelitian ini adalah bahan bioaktif seperti hydroxyapatite (HA) dan calcium metaphosphate (CMP), serta potensi hidroksiapatit dari tulang ayam sebagai alternatif pelapis implan gigi. Selain itu, pentingnya edukasi masyarakat melalui penyuluhan berbasis agama juga dieksplorasi untuk meningkatkan penerimaan teknologi ini. Metode yang digunakan dalam penelitian ini adalah tinjauan literatur dan analisis hasil penelitian terkait. Penelitian yang dianalisis meliputi studi tentang modifikasi permukaan implan gigi dengan bahan bioaktif, potensi hidroksiapatit dari tulang ayam, dan penelitian tentang penyuluhan masyarakat mengenai implan gigi dalam perspektif Islam. Analisis dilakukan dengan membandingkan hasil penelitian yang ada dan menyimpulkan temuan utama dari masing-masing studi. Hasil penelitian menunjukkan bahwa modifikasi permukaan implan dengan bahan bioaktif dapat meningkatkan penyembuhan tulang dan keberhasilan oseointegrasi. Lapisan CMP terbukti lebih unggul dibandingkan HA dalam ketahanan terhadap delaminasi dan pengurangan partikel yang dapat menyebabkan kegagalan implan. Modifikasi permukaan implan dengan bahan bioaktif seperti CMP dan HA memberikan kontribusi penting dalam meningkatkan osseointegrasi dan stabilitas implan. Selain itu, penggunaan hidroksiapatit dari tulang ayam sebagai alternatif pelapis implan memberikan solusi biaya efektif dan berpotensi mengurangi biaya pengembangan implan gigi. Modifikasi permukaan implan dengan bahan bioaktif seperti HA dan CMP dapat meningkatkan keberhasilan oseointegrasi, dengan CMP menunjukkan keunggulan. Selain itu, hidroksiapatit dari tulang ayam menawarkan solusi biaya efektif dalam pengembangan implan gigi.
Effectiveness of Acemannan Hydrogel Administration at Concentrations of 25%, 50%, 75% Against Decrease in the Number of Macrophages in Periodontitis Rats with Diabetes Mellitus Susanto, Chandra; Halim, Susanna; Rusip, Gusbakti; Aurelia, Nada
Jurnal Penelitian Pendidikan IPA Vol 10 No 4 (2024): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i4.7077

Abstract

Acemannan activity as a natural polysaccharide from Aloevera has good biodegradability and biocompatibility and has an effect on cell tissue repair. The study's objective was to ascertain whether giving Hydrogel Acemannan at concentrations of 25%, 50%, and 75% would be beneficial in lowering the quantity of macrophages in diabetic periodontitis mice . 48 white Wistar rats were used as research samples, and they were split into four groups at two different observation intervals (days 3 and 7).One-way ANOVA and posthoc LSD statistical tests were used to assess the data. The number of macrophages in each group decreased on day 7 to 3.50 ± 0.354; 2.79±0.431; 1.54 ± 0.292; 0.54 ± 0.292. The results of the one-way ANOVAX test (p≤0.05) showed that the Hydrogel Acemannan concentrations of 25%, 50%, and 75% were effective in reducing the number of macrophages in periodontitis mice with diabetes mellitus. The results of the LSD posthoc test showed that Hydrogel Acemannan concentrations of 25%, 50%, and 75% were substantially more effective than the positive control in reducing the number of macrophages in periodontal mice with diabetes mellitus (p≤0.05).
Effectiveness of Andaliman Extract on Blood Sugar Levels of White Mice Induced by STZ HOMA-IR Dhillon, Jessyca Manishwer Kaur; Chiuman, Linda; Rusip, Gusbakti
Jurnal Penelitian Pendidikan IPA Vol 10 No 12 (2024): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i12.9163

Abstract

The increasing cases and treatment costs have triggered the search for alternatives, such as Andaliman, which is believed to have antidiabetic and antioxidant activities, induced by Streptozotocin (STZ). Objective: to determine the effectiveness of Andaliman nanoemulsion extract in lowering blood sugar levels, overcoming insulin resistance as measured by HOMA-IR, in white mice induced by Streptozotocin (STZ). The study employed a posttest only controlled group design, using sic groups of mice, each of which had five mice weighing 150–260 grams in STZ induction (65 mg/kg), the positive control group used STZ + Metformin, the treatment group used a dose of Nanoandaliman of 25.50 & 75 mg/KgBB. KGD examination was carried out after 7.14 and 21 days after STZ induction. Results: Based on the lowest KGD measurement on day 21 in the STZ65mg/kgBB + NA50 mg/kgBB treatment group, in the HOMA-IR measurement, the highest value was found in the negative control (STZ 65mg/kgBB) on day 21. This indicates that the decrease in blood glucose levels with STZ65mg/kgBB + NA50 mg/kgBB treatment is better than other treatments on day 21. Conclusion: STZ65mg/kgBB + NA50 mg/kgBB treatment has been proven to be effective in lowering blood sugar levels. It is expected that the results of this study can become an alternative treatment for diabetes in the future
Antidiabetic Activity of Cep-Cepan Leaf Extract Nanoparticles (Castanopsis costata) in Streptozotocin-Induced White Rat Models Ginting, Astriani Natalia Br; Ginting, Chrismis Novalinda; Rusip, Gusbakti; Chiuman, Linda
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.9408

Abstract

The cep-cepan plant (Castanopsis costata) from the Fagaceae family is traditionally used by the Karo community in Medan, North Sumatra, to treat diabetes mellitus, although its efficacy has not yet been scientifically proven. This study aimed to evaluate the effectiveness of the antidiabetic activity of cep-cepan leaf extract nanoparticles (Castanopsis costata) in a streptozotocin-induced white rat model. A total of 25 male white rats were divided into five treatment groups: a positive control group, a negative control group, and three experimental groups treated with extract concentrations of 25, 75, and 150 mg/kg body weight, respectively. Plasma glucose levels were measured every 72 hours for 15 days using blood samples taken from the tail. Pancreatic tissue was then examined, and the data were analyzed using one way anova. The findings showed significant antidiabetic activity in all treatment groups, with p < 0.001. The nanoparticle extract of cep-cepan leaves exhibited the highest antidiabetic potential at a dosage of 150 mg/kg, reducing blood glucose levels by 59.39%. These results suggest that the nanoparticle extract of cep-cepan leaves demonstrates antidiabetic activity in the streptozotocin-induced white rat model, and it has the potential to be developed as an alternative treatment for diabetes mellitus.
Potensi Daya Inhibisi Ekstrak Etanol Daun Sirih Merah (Piper crocatum Ruiz & Pav) Terhadap Mikroorganisme Pada Biofilm Di Pelat Gigi Tiruan Berbahan Hot Curing Acrylic Halim, Susanna; Rusip, Gusbakti; Syarbaini, Siti Farah
Jurnal Penelitian Pendidikan IPA Vol 11 No 3 (2025): March
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i3.10825

Abstract

Tooth loss reduces quality of life by affecting chewing and speech function and can interfere with social activities. Hot curing acrylic dentures have the disadvantage of high porosity and surface roughness, so they are susceptible to food residues and microorganisms that can lead to the formation of biofilm and denture stomatitis. Red series leaves (Piper crocatum Ruiz & Pav) have chemical content such as flavonoids, alkaloids, and essential oils that have the potential to be antimicrobials. This study aims to determine the potential of red betel leaf ethanol extract in inhibiting microorganisms in biofilms in denture plates made of hot curing acrylic. This study used the liquid dilution method to test the effectiveness of red betel leaf ethanol extract with concentrations of 10%, 25%, 50% and 75% on the growth of Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans contaminated on round denture plates made of hot curing acrylic. The results showed that the ethanol extract of red betel leaf significantly reduced the number of bacterial and fungal colonies, with a concentration of 75% showing the highest effectiveness, especially against the bacterium Lactobacillus acidophilus with an average colony count of 45.67 ± 4.04. Red betel leaf ethanol extract contains chemical compounds that are effective as antimicrobials in biofilms in denture plates made of hot curing acrylic. This extract has the potential to be an alternative natural ingredient for denture cleaning.
Co-Authors Aditya Candra AMELIA EKA DAMAYANTI Anita Surya Arianti, Ara Safitri ASHIL MUHAMMAD ABDUL RASYID Aurelia, Nada Bangun, Primta Bintang Y.M Sinaga Caroline S, Cecilia Chiuman, Linda Daniel Yantonius Simamora DEWI SARTIKA Dhillon, Jessyca Manishwer Kaur Dhillon, Neha Amar Doli, Doni Dwi Astuti Manullang Edy Fachrial ELMAN BOY Erawati, Suci Esther R. D. Sitorus FAWWAZ NAUFAL RACHMADI Fiska Maya Wardhani Fitri Inriani Silaban Ginting, Astriani Natalia Br Ginting, Chrismis Novalinda Hafiz Anugrah Mursyid Halim, Susanna Harianto Bangun Henny Henny, Henny HUDDY ARTICA SINULINGGA Joanna Elvia Harefa Karolina Br Surbakti Kurniawan, Gracella Verren M. Ichwan Mangatas Silaen Mangkuanom, Adrian Saleh Manihuruk, Fani Nuryana Martina Evelyn R.H Melviana Lubis Member Reni Purba Meutia, Rena Muharraran, Firdha Mursyid, Hafiz Anugrah Mutia, Maya Sari NABILA HANA SYAQILA Nadia, Felanda Ahsan NANDA SYAVIRA Napitupulu, Olivia Des Vinca Albahana Nathasia, Ingee Ong, Gabriella Fransisca Purba, Member Reni Putra, Ananda Rahmat PUTRI SARMADANI HASIBUAN QORY AULIA DANA LUBIS Razoki Riamah, Riamah Rianingsih, Rika Robitah Asfur Rosa Paradita Dalimunthe Sagala, Agasy Gideon Admiral Salsabilah Shieny Lokanata Sinaga, Theresia Margaretha Sinurat, Ariel Oertega Suandy, Suandy Suci Erawati Sulistijanto, Eddy Susanto, Chandra Syarbaini, Siti Farah Syarifah, Anita Tambunan, Adrian Nurrachman Tambunan, Andika Zayani Tarigan, Elviyanti Tiarnida Nababan Vivin Lydia Wafi Aqilah Yafa Wibowo, Angga Arjuno Yetty Machrina Zul Alfian