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All Journal Medula E-Dimas: Jurnal Pengabdian kepada Masyarakat Jurnal Penelitian Pendidikan IPA (JPPIPA) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Manuju : Malahayati Nursing Journal JURNAL PENELITIAN PERAWAT PROFESIONAL JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Kesehatan Tambusai Bioscientist : Jurnal Ilmiah Biologi Dharma: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Sosial Indonesia Jurnal Pengabdian Masyarakat Jurnal Pengabdian Multidisiplin Indonesia JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Suryadi Islami
Fakultas Kedokteran, Universitas Lampung
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Journal : Medula

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Analisis Fear of Failure (FoF) pada Mahasiswa Kedokteran Vidini Caya, Tazkia; Oktafany, Oktafany; Islami, Suryadi
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.988

Abstract

Fear of failure is a person's response to the failure they experience and anticipation to avoid the bad consequences of that failure. Fear of failure can have both positive and negative impacts. Anyone can experience fear of failure, including medical students as students who are pursuing an education full of challenges and responsibilities. Medical students take a longer period of education and bear greater demands and roles than other students. To determine the level of fear of failure, the researchers used a research instrument in the form of a questionnaire, namely the Performance Failure Appraisal Inventory (PFAI). Universally, medical education educates students with the academic achievements that need to be achieved to obtain a license and guarantee a bright future. Without academic achievement and good achievement, degrees and job opportunities, even continuing education will not be easy to obtain. The level of fear of failure varies based on gender, academic year, Grade Point Average (GPA), interest in medical science, etc. Fear of failure shows a negative relationship with medical student learning achievement. Thus, fear of failure in medical students needs to be a concern for educational institutions in understanding student behavior and shaping the scope of teaching and providing counseling that can help medical students overcome the fear of failure.
Teknik Penyuntingan Gen Clustered Regularly Interspaced Short Palindromic Repeats-Cas9 (CRISPR-Cas9) sebagai Terapi Penyakit Genetik Bawaan: Ulasan Literatur Islami, Suryadi; Haq, Rais Amaral; Arianto, Nayla Nadhifa; Sabina, Diana Larisa
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.999

Abstract

The development of therapy for inherited genetic diseases using CRISPR-Cas9 technology has shown significant progress. This article discusses the history and working principles of CRISPR-Cas9, highlighting its applications in the therapy of inherited genetic diseases. Current research focuses include diseases such as cystic fibrosis, thalassemia, and Duchenne muscular dystrophy. Genetic therapy with CRISPR-Cas9 involves editing specific genes to correct disease-causing mutations, opening up opportunities for more effective treatments. Regarding the use of this technique, there are various difficulties, such as potential off-target effects, ethical issues, and long-term safety. However, efforts continue to be made to improve the specificity and accuracy of CRISPR-Cas9 so that the development of effective delivery methods and improving safety has become a major focus of research. Potentially, CRISPR-Cas9 could become a more specific and personalized genetic therapy, opening up opportunities to treat genetic diseases at the molecular level and providing alternative therapies for diseases that were previously difficult to treat. In addition, this technology has the potential for early prevention of genetic diseases and the development of more affordable gene therapies. Interdisciplinary collaboration is key in optimizing the potential of CRISPR-Cas9 to ensure the development of genetic disease therapies that are ethical and beneficial to human health in the future.
Faktor Risiko yang Dapat Diubah pada Demensia Lansia: Ulasan Literatur Naratif Singkat Hatimi, Fahmi Ilham; Hardiansyah, Ridwan; Islami, Suryadi
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1182

Abstract

The gradual neurological disease known as dementia causes a substantial reduction in cognitive function, which impairs an older person's capacity to carry out everyday tasks on their own. Dementia is a serious worldwide health concern since its prevalence rises with age. Through a narrative literature review, this study seeks to uncover modifiable risk factors for dementia in the elderly. Utilizing the terms "dementia risk factors," "factors of dementia," and "dementia in elderly," information was obtained from databases including Google Scholar, Garuda, and NCBI. The results show that reducing alcohol intake, quitting smoking, managing diabetes mellitus, and engaging in regular physical activity are all effective ways to avoid dementia. Increased cerebral blood flow from exercise supports cognitive function and slows the progression of dementia. Quitting smoking and drinking less alcohol reduces oxidative stress, inflammation, and neurotoxic damage—all of which hasten the onset of neurodegenerative diseases. Controlling diabetes helps avoid hypoxia and vascular damage, both of which can worsen cognitive impairment. These lifestyle changes not only lessen the risk of dementia but also greatly lessen the financial, social, and emotional strain on people, families, and communities. This article highlights the value of early intervention through lifestyle modifications and how it can enhance older people's overall quality of life. It offers practical advice on how to lessen the effects of dementia, one of the most important health issues of our time.
Infeksi Cryptosporidium pada Manusia: Patogenesis, Diagnosis dan Terapi Hatimi, Fahmi Ilham; Mutiara, Hanna; Islami, Suryadi; Sukohar, Asep
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1261

Abstract

Cryptosporidium is a zoonotic protozoan parasite capable of infecting humans and animals, primarily transmitted through contaminated water or food. This infection is a leading cause of moderate to severe diarrhea, particularly in children from low-income regions and immunocompromised individuals, contributing to significant global morbidity and mortality. The pathogenesis of Cryptosporidium involves the invasion of intestinal epithelial cells, resulting in mucosal damage, villous atrophy, and increased intestinal permeability, leading to watery diarrhea. Local inflammatory responses exacerbate symptoms, while immunocompromised individuals often experience chronic infections with serious complications. Diagnosis relies on microscopy, immunofluorescence, and molecular techniques such as PCR, which offer high sensitivity and specificity. Supportive care is the mainstay of treatment, with nitazoxanide being the preferred therapeutic option for selected patients. For immunocompromised individuals, management is more complex and may involve immune restoration therapies, such as antiretroviral treatment for HIV/AIDS patients. However, resistance to conventional treatments remains a significant challenge, necessitating further research into novel therapeutic agents, such as KDU731, which has shown promising efficacy in preliminary studies. This review provides a comprehensive analysis of the pathogenesis, diagnostic methods, and therapeutic strategies for Cryptosporidium infections. Additionally, it highlights the importance of prevention measures, including improved access to clean water and public health education. Enhanced control efforts are crucial to mitigating the global health impact of this infection, particularly among vulnerable populations such as children and immunocompromised individuals.
Co-Authors Adelia Farisa Adisti, Fransiska Afriyani Afriyani Afriyani, Afriyani Afriyani, Afriyani ani Ambarwati, Endah Andika S.D.R. Andrifianie, Femmy Arafah, Aisyah Putri arby tamaila Arianto, Nayla Nadhifa Arif, Ahmad Fauzan Arif, Muhammad Farhan Asep Sukohar Atmaja, Ghozi Purna Bachtiar, Nabylly Aghna Callista, Eugenia Centya Cheirini Damayanti, Ervina Daudea Kirana Sari Dita Noviyanda Saerulloh Djamilu, Berneta Rendiana Dwi, Farah Ergidona Nurizqi Ervina Damayanti Ervina Damayanti Ervina Damayanti Ety Apriliana Ety Apriliana Evy Afriyani Farhana, Lubna Fauzi Ahmad Muda Febriana, Triana Femmy Andrifianie Fitria Saftarina Habib, Farid Alif Hafizh, Ahmad Fauzan Hanna Mutiara, Hanna Haq, Rais Amaral Hardiansyah, Ridwan Hatimi, Fahmi Ilham Ihsanti Dwi Rahayu Ikhsan, Muhammad Ali Indri Windarti Irma Nur Humaida Januaristy, Gracia Rescuefa Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi Khairun Nisa Kirana, Shela Sandra Laksana, Bayu Larasati, Ratri Mauluti Linda Septiani Luhut Uji Arto Naenggolan M. Rifqi Efendi Magistra, Muhammad Akbar Marcellia, Selvi Mesa Sukmadani Rusdi Mighuel A.S.N. Muhammad Fitra Wardhana Sayoeti Muhammad Maulana Muhammad Ricky Ramadhian Nadly, Alan Arindo Natasya Karren Zeta Nisa Karima Nugraha, Dian Sastra Oktafany, Oktafany Panjaitan, Annisa Tamara Pardilawati, Citra Yuliyanda Putri Handayani Putri, Eka Meilinda Putri, Reny Arienta Qonita, Adzrok Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rika Lisiswanti Rizki Hanriko Rizki Nisfi Ramdhini Rosa, Emantis Rossa, Putri Emylia Rudiyanto, Waluyo Sabina, Diana Larisa Sari, Dewi Hambar Selvi Marcellia Septiani, Linda Sitanggang, Grety Thessalonica Sofyan Musyabiq Wijaya Sri Suciati Ningsih Suci Nurhaliza Suri, Nurma Susianti Susianti, Susianti Syiffatulhaya Syiffatulhaya Temun, Jedo Muchamad Tias Triavina Khairunisa Vanadis, Zifa Aisha Vestinaliyou, Nanda Vidini Caya, Tazkia Wijaya, Ardia Syifa Winda Winda Yustina Yustina