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Rahma Diyan Martha
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Journal : JURNAL PHOTON

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Uji Toksisitas Ekstrak Etanolik Batang Tanaman Majapahit (Crescentia cujete) Terhadap Artemia salina Leach Rahma Diyan Martha; Fatimah
Sistem Informasi Vol 11 No 1 (2020): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v11i1.2146

Abstract

Cancer is a disease characterized by uncontrolled cell growth and the ability of these cells to attack biological tissue. Various attempts have been made, one of them with treatment to kill cancer cells, but not a few of these efforts actually cause side effects. This fact demands the need for a safe alternative way to treat cancer using natural ingredients. One of the local natural resources that has the potential to treat cancer is Majapahit (Crescentia cujete). In this study, Majapahit (C. cujete) stem extracts were carried out which have anticancer activity. The first stage was screening by conducting a qualitative analysis of the ethanol extract of the stem of the majapahit plant (C. cujete). Furthermore, a toxicity test was carried out against Artemia salina Leach using the Brine Shrimp Lethality Test (BST) method. Phytochemical testing was carried out to check the content of secondary metabolite compounds contained in the majapahit stem extract, and the results were positive for flavonoids, tannins, saponins and phenolics. This data, supported by spectrophotometric tests, proved that the largest concentration of the ethanolic extract of the majapahit (C. cujete) stem was 24.05% tannin. Then the LC50 test from the toxicity test of the active component of majapahit plant stem extract (C. cujete) against Artemia salina Leach showed a concentration of 0.01 µg / mL and 0.04 µg / mL, namely with a percentage below 50%.
Co-Authors 'Aini, Febriana Devi Nur - Fatimah Adisyaningrum, Ega Nurgia Aena Laili Afidatul Muadifah Afidatul Muadifah Ahmad Yudianto Algafari Bakti Manggara Amalia Putri Eka Anas Fadli Wijaya Anisa Azizah Annisah Mahanani Aprilia, Chatrina Apriliani, Herlina Arif Santoso Arif Santoso Asmarani Kusumawati Atiqoh Zummah Ayu Insa Ayu Insa Fajri Azriel Restu Azriel Restu Chairil Anwar Choirul Huda Choirul Huda Danar Danar Danar Danar Danar, Danar Dara Pranidya Tilarso Dita Arindea Tunggal Putri Dyah Setyaningrum, Dyah Ega Nurgia Adisyaningrum Ega Nurgia Adisyaningrum Elen Vikelavianis Elen Vikelavianis Ema Krismawar Sari Ema Krismawar Sari Fadila, Natasya Nurul Fajri, Ayu Insa Fatimah Fatimah Fatimah fatimah Fatimah Fatimah Fatimah Fuzianingsih, Eka Novia Hesty Parbuntari Ika Rachutami ika Rachutami Ita Rhosida Ita Rhosida Jalu Prakoso Jalu Prakoso Kartika Arum Wardani Kharisma, Mei Nabila Revina Kholifah, Siti Nurriyatul Kristianto, Sonny Kristina Handayani Kumalasari, Nurul Chamidah Lestari, Nasa Bela Dwi Maida, Margarita Claudya Mashudi Mashudi Maya Diva Maya Diva Siswidiani Muadifah, Afidatul Muadifah, Afidhatul Mutia Hariani Murjanah Mutia Hariani Nurjanah Nasa Bella Ngibad, Khoirul Niken Desi Wulandhari Nurin, Wachidatun Nurjanah, Mutia Hariani Nurul Chamidah Kumalasari Nurul Chamidah Kumalasari Nurul Chamidah Kumalasari Nurul Chamidah Kumalasari Parbuntari, Hesty Parbuntary, Hesty Putri, Amalia Eka Rahmadani, Anindita Mutiara Rahmawati, Ayu Sintya Citra Ramadhani, Melati Apriliana Retnosari, Rini Rian Anggia Wijaya Rury Eryna Putri Safitri, Yunita Diyah Sefrina Sefrina Siti Awwalul Amanatur Rohmah Siti Nurriyatul Kholifah Sri Wahyuningsih SULASTRI Sulastri Sulastri Tilarso, Dara Pranidya Tutik Dwi Wahyuningsih Ulayya, Nida Asma vifta, rissa laila Widayanti, Sindi Dwi Wimbuh Tri Widodo Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Wulandhari, Niken Desi Yuliandari, Fadhira Yulindasari, Armita Regina Putri