Claim Missing Document
Check
Articles

Effects of Sacha Inchi Tempeh on Oxidative Stress in Rats with Metabolic Syndrome Nafisah; Anjani, Gemala; Afifah, Diana Nur; Syauqy, Ahmad; Mahati, Endang; Astawan, Made; Rahmawati, Irma Sarita
Indonesian Journal of Human Nutrition Vol. 11 No. 2 (2024)
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijhn.2024.011.02.1

Abstract

Metabolic syndrome is a condition caused by metabolic disorders such as overweight, obesity, physical inactivity, and genetic factors. Increased reactive oxygen species (ROS) production in metabolic syndrome causes oxidative stress, characterized by decreased antioxidant capacity, increased malondialdehyde (MDA), and decreased superoxide dismutase (SOD) enzymes. Sacha inchi has a high alpha-linolenic acid (ALA) content, tocopherols, and antioxidants that can help protect liver tissue from damage caused by oxidative stress in metabolic syndrome. This study aimed to evaluate how sacha inchi tempeh affects the levels of MDA, SOD enzyme, and total antioxidant capacity (TAC) in Wistar rats with metabolic syndrome induced by a high-fat high-fructose diet (HFFD). The study used a true experimental pre-and post-control group design on rats with the intervention of sacha inchi tempeh (0.9 g, 1.8 g, 3.6 g) for 5 weeks (35 days). The ELISA (Enzyme-Linked Immunosorbent Assay) method with the FineTest procedure was used to measure levels of TAC, MDA, and SOD enzymes. The results of paired T-tests showed a significant difference in TAC levels before and after the intervention in the intervention group compared to the healthy group (p<0.05). MDA and SOD enzyme levels in rat liver tissue also improved significantly (p<0.05). Compared to simvastatin medication therapy, sacha inchi tempeh at a dose of 3.6 g had the best results. Therefore, sacha inchi tempeh is beneficial as a nutraceutical meal in reducing oxidative stress in individuals suffering from metabolic syndrome.
Effect of Leunca Fruit (Solanum nigrum L.) on Oxidative Stress in rats fed a High Fat High Sucrose Diet Nurdin, Nurhanifah Muthmainnah; Muis, Siti Fatimah; Anjani, Gemala; Noer, Etika Ratna; Ayustaningwarno, Fitriyono
Poltekita: Jurnal Ilmu Kesehatan Vol. 18 No. 3 (2024)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v18i3.3818

Abstract

Decreased levels of superoxide dismutase (SOD) and increased levels of malondialdehyde (MDA) are markers of oxidative stress and indicate obesity. Leunca fruit (Solanum Nigrum L) is a plant that contains antioxidants that can reduce the level of oxidative stress in obesity. The purpose of this study was to determine the effect of leunca fruit administration on SOD and MDA levels in obese rats. This type of research is true experimental with a post-test-only research design where 30 male Sprague Dawley rats were divided into five groups consisting of 2 control groups K(-) and K(+) and three treatment groups (P1, P2, P3). Groups K+, P1, P2, and P3 were fed a high-fat and sucrose diet (21% lard, 34% sucrose). The K (-) control group is a group of healthy rats that only receive standard feed without being given leunca fruit. Group K (+) is a group of obese rats without leunca fruit. Leunca fruit was given for six weeks at a dose of 0.8g (P1), 1.6g (P2), and 2.4g (P3). Serum SOD levels were measured by ELISA method and MDA levels were measured by TBARS method. Statistical analysis using One Way Anova test. Administration of leunca fruit with graded doses can significantly increase SOD activity p=0.000 (p<0.05) and can significantly reduce MDA levels in obese rats in each treatment group p=0.000 (p<0.05). Leunca fruit with a dose of 2.4g/BB rat is the most effective dose to increase SOD levels and reduce MDA levels. The limitation of this study that there is no weighing of the remaining rat feed at each meal, so that the percentage of rat intake is was unknown.
Effects of Sacha Inchi Tempeh on Oxidative Stress in Rats with Metabolic Syndrome Afifah, Diana Nur; Nafisah; Anjani, Gemala; Syauqy, Ahmad; Mahati, Endang; Astawan, Made; Rahmawati, Irma Sarita
Indonesian Journal of Human Nutrition Vol. 11 No. 2 (2024): In Press
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Metabolic syndrome is a condition caused by metabolic disorders such as overweight, obesity, lack of physical activity, and genetic factors. Increased ROS production in metabolic syndrome causes oxidative stress characterized by decreased antioxidant capacity, increased MDA, and decreased SOD enzymes. Sacha inchi has a high ALA content that can increase omega-3 levels, tocopherols, and antioxidants that can help protect liver tissue from damage caused by oxidative stress in metabolic syndrome.The purpose of this study was to look at how sacha inchi tempeh affected the levels of malondialdehyde, superoxide dismutase enzyme, and overall antioxidant capacity in rats with metabolic syndrome brought on by a diet high in fat and fructose. The method used in the research is an experiment with a pre-and post-control group design on Wistar strain white rats with metabolic syndrome induced by HFFD, with the intervention of sacha inchi tempe (0.9 g; 1.8 g; 3.6 g) for 5 weeks (35 days). The results of the study with paired T-tests were that there was a significant difference in TAC levels before and after the intervention in the intervention group with a p-value of <0.05 compared to the healthy group. MDA and SOD enzyme levels in rat liver tissue also were significant improvement with a p-value of <0.05. When compared to simvastatin medication therapy, sacha inchi tempeh at a dose of 3.6 g had the best results. Therefore, it is established that sacha inchi tempeh is beneficial as a nutraceutical meal in reducing oxidative stress in individuals suffering from metabolic syndrome.
Kadar MDA (Malondialdehyde) dan Aktivitas SOD (Superoxide Dismutase) pada Tikus Defisiensi Vitamin D dan Kalsium: Malondialdehyde (MDA) Levels and SOD (Superoxide Dismutase) Activity in Vitamin D and Calcium Deficiency Rat Untari; Gemala Anjani; Faizah Fulyani; Reza Achmad Maulana
JURNAL GIZI DAN KESEHATAN Vol. 17 No. 1 (2025): JURNAL GIZI DAN KESEHATAN
Publisher : UNIVERSITAS NGUDI WALUYO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/jgk.v17i1.732

Abstract

Vitamin D and calcium deficiencies are often associated with increased oxidative stress. Oxidative stress conditions can cause cell damage and metabolic stress and induce degenerative diseases. Several parameters that are often used to measure oxidative stress are MDA (malondialdehyde) and SOD (superoxide dismutase) which can be found in blood or body tissue. This study aims to determine MDA levels and SOD activity in the livers of mice with vitamin D and calcium deficiency. This research used a pre-experimental design with a static group comparison design. A total of 12 male Wistar white rats (Rattus novergicus) were divided into two groups. The first group (K+) is a healthy control group without any treatment and the second group (K-) is a deficiency group given feed without vitamin D and calcium content (Modified AIN-93M (vitamin D and calcium depleted)). After 14 days of treatment, the MDA levels and SOD activity in the liver tissue were seen. MDA levels were measured using TBARS (Thiobarbituric Acid Reactive Substances) and SOD activity was measured using the Superoxide Dismutase (SOD) Activity Assay Kit. The results showed that MDA levels in the deficiency group (K-) were higher than in the control group (p<0.001) and SOD activity was lower than in the control group (p<0.001). MDA levels were higher and SOD activity was lower in the group of deficient mice (K-) compared to the group of healthy control mice (K+). Vitamin D and calcium deficiency conditions increase oxidative stress conditions in the liver of rat.   ABSTRAK Defisiensi vitamin D dan kalsium sering dihubungkan dengan peningkatan stress oksidatif. Kondisi stres oksidatif dapat menyebabkan kerusakan sel dan stress metabolik dapat menginduksi penyakit degenerative. Beberapa parameter yang sering digunakan untuk mengukur stres oksidatif yaitu MDA (malondialdehyde) dan SOD (superoxide dismutase) yang bisa ditemukan di darah atau jaringan tubuh. Penelitian ini bertujuan untuk mengetahui kadar MDA dan aktivitas SOD pada organ hati tikus dengan defisiensi vitamin D dan kalsium. Penelitian ini menggunakan rancangan pra-eksperimental (pre-experimental) dengan design static group comparison. Sebanyak 12 ekor tikus putih (Rattus novergicus) jantan galur Wistar dibagi menjadi dua kelompok. Kelompok pertama (K+) yaitu kelompok kontrol sehat tanpa diberikan perlakuan apapun dan kelompok kedua (K-) yaitu kelompok defisiensi dengan diberikan pakan tanpa kandungan vitamin D dan kalsium (AIN-93M Termodifikasi (vitamin D and calcium depleted)). Setelah 14 hari perlakuan, dilihat kadar MDA dan aktivitas SOD di jaringan organ hati. Pengukuran kadar MDA menggunakan TBARS (Thiobarbituric acid reactive substances) dan pengukuran aktivitas SOD dengan menggunakan Superoxide Dismutase (SOD) Activity Assay Kit. Hasil penelitian menunjukkan kadar MDA pada kelompok defisiensi (K-) lebih tinggi dibandingkan kelompok kontrol (p< 0.001) dan aktivitas SOD lebih rendah dibandingkan kelompok kontrol (p<0.001). Kadar MDA lebih tinggi dan aktivitas SOD lebih rendah pada kelompok tikus defisieni (K-) dibandingkan kelompok tikus kontrol sehat (K+). Kondisi defisiensi vitamin D dan kalsium meningkatkan kondisi stres oksidatif pada organ hati tikus.
Striped catfish oil and turmeric extract reduces inflammation in metabolic syndrome rats Mambaya, Helvi Desi; Muniroh, Muflihatul; Afifah, Diana Nur; Anjani, Gemala; Pramono, Adriyan; Sulchan, Mohammad
International Journal of Public Health Science (IJPHS) Vol 14, No 2: June 2025
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v14i2.24984

Abstract

Metabolic syndrome is a growing global health problem. Long-term treatment for metabolic syndrome causes side effects. Therefore, the use of nutraceuticals could also be considered. This study analyzed the effect of the administration of striped catfish oil and turmeric extract on tumor necrosis factor-α (TNF-α) levels and homeostasis model assessment of insulin resistance (HOMA-IR) in metabolic syndrome rats. Metabolic syndrome was induced in rats by administration of high fat fructose diet (HFFD) containing 3 g pork fat (15%), 2 g duck egg yolk (10%), 15 g standard diet (75%), and 2 ml fructose (1%). Thirty rats were randomized into five groups: C1 (normal control group), C2 (metabolic syndrome control group without treatment), P1 (striped catfish oil at 0.08 ml/200 g BW/day), P2 (turmeric extract at 5.04 mg/kg BW/day), P3 (combination of striped catfish oil at 0.08 ml/200 gBW/day and turmeric extract at 5.04 mg/kg BW/day). There was a significant decrease (p<0.05) in TNF-α levels and HOMA-IR in treatment groups (P1, P2, P3) compared to C2. The P3 group had the lowest TNF-α levels. Treatment groups had the same potential effect in reducing HOMA-IR. Striped catfish oil, turmeric extract, and their combination reduce inflammation and insulin resistance in metabolic syndrome rats.
Pengaruh pemberian actinomycetes terhadap penurunan jumlah leukosit pada mencit diare Ivena Claresta; Endang Sri Lestari; Gemala Anjani
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 2 (2024): April
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i2.1445

Abstract

Background: Diarrhea cases are mostly caused by enteropathogenic escherichia coli (EPEC).  Elevated white blood cells or leucocytes are closely associated with the incidence of diarrhea due to bacterial infection. Actinomycetes are known to have antibacterial properties that can fight pathogenic microorganisms.Objectives: To analyze of the effectiveness of Actinomycetes from the right wing of Musca domestica on leucocyte counts in EPEC-induced mice.Methods: Experimental study with randomized post-test only with control group design. This study was conducted from June to July 2023 at the Pharmacology Laboratory of Muhammadiyah Surakarta University, using 30 mice divided into 5 groups. Actinomycetes intervention was given equivalent to 0,5 McFarland standard with dose variations:  0,26ml/20gBW (group P1), 0,65ml/20gBW (group P2), and 1,3ml/20gBW (group P3). EPEC induction was 0,5ml orally in the treatment group and negative control group (KN).  The healthy control group (KS) was given 0,5ml of mineral water. The variable measured was the number of leucocytes of Mus musculus mice taken on the third day after the intervention. Data processing was performed using the Kruskall-Wallis Test to determine differences between groups with level significantly p<0,05.Results: There was a decrease in the leucocytes counts in the treatment group compared to the KN group (p=0,027). The highest mean leukocyte count was seen in the KN group (8.786,7 mm3) while, the lowest mean leukocyte count was in the P2 group (6.48,3 mm3).Conclusion:  Actinomycetes intervention in EPEC-induced diarrhea mice effectively reduces leucocyte counts.KeywordActinomycetes, Leukocyte, Diarrhea
Effect of leunca (Solanum nigrum) on inflammatory status in rats induced by high-fat and high-sucrose diet Gunawan, Sekar Ayu Putri; Muis, Siti Fatimah; Anjani, Gemala; Noer, Etika Ratna; Ayustaningwarno, Fitriyono
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.99-104

Abstract

Background: Consumption of foods that are high in calories over a long period of time is a cause of obesity and can increase proinflammatory cytokines. Leunca fruit contains various phytochemicals that act as anti-inflammatory, antioxidant, and antiobesity but not many people utilize leunca fruit as daily food.Objective: To analyze the effect of leunca fruit on TNF-α and IL-6 levels in rats induced by high fat and sucrose diet (HFSD).Methods: The research design was Randomized Post Test Only Control Group Design. The sample was 30 male Sparague Dawley rats and divided into 5 groups, namely group K1 which was given standard feed, group K2 which was induced by HFSD, group P1 which was induced by HFSD and leunca 0.8g/200gBW, group P2 which was induced by HFSD and leunca 1.6g/200gBW, and group P3 which was induced by HFSD and leunca 2.4g/200gBW. The research was conducted at the Nutrition Laboratory of the Center for Food and Nutrition Studies of Gadjah Mada University (PSPG PAU UGM) Yogyakarta in January-March 2024. Testing TNF-α and IL-6 levels through rat blood serum using the ELISA method. Data were analyzed by ANOVA and Post Hoc test.Results: There was a significant difference in TNF-α and IL-6 levels between experimental groups (p=0.00). The levels of TNF-α and IL-6 in the P1, P2, and P3 groups that received HFSD + leunca were lower than in the K2 group that received HFSD only.Conclusion: Leunca fruit can reduce proinflammatory cytokine levels (TNF-α and IL-6) in HFSD-induced rats.
Potensi Bahan Baku Produk Pangan Darurat di Asia Tenggara: Potential Raw Materials for Emergency Food Products in Southeast Asia Resti, Nina; Ayustaningwarno, Fitriyono; Anjani, Gemala; Syauqy, Ahmad; Nuryanto, Nuryanto; Chasanah, Ekowati; Purwani, Endang Yuli; Zhu, Fan; Afifah, Diana Nur
Amerta Nutrition Vol. 9 No. 2 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i2.2025.362-376

Abstract

Background: The occurrence of natural disaster in Southeast Asia due to its location along the Asia Pacific Ring of Fire is high. The consequences of the natural disasters on various aspects, like that social, financial, and food security can be large. This initiative promotes the development of emergency food products to address the daily nutritional requirements of natural disaster victims, ensuring their survival. The specified standard is 2,100 kcal/day, emphasizing a balanced distribution of macronutrients (40-50% carbohydrates, 35-45% fat, and 10-15% protein). Objectives: This literature review explored the potential raw materials for emergency food products in the Southeast Asia. Methods: This review utilized databases from Google Scholar and PubMed websites, employing specific keywords for each identified category to gather the latest literature. The literature obtained was 10 article. Discussions: This review explores solutions to the challenges posed by natural disasters in Southeast Asia, focusing on the potential use of locally available resources as raw materials for emergency food products. Raw materials, including Fish Hydrolyzate Protein (FPH), offer numerous benefits due to their bioactive contents, such as antioxidant, antihyperglycemic, antimicrobial, antitumor, ACE inhibitor activity, calcium binding, and anticoagulant properties, particularly beneficial for vulnerable groups. The review also delves into the elimination of raw materials, the nutritional content of various types of emergency food products, and innovative solutions for emergency food products in Southeast Asia. Conclusions: The potential raw materials identified have the capability to yield innovative emergency food products with both excellent physicochemical quality and health potential.
Antibacterial Potential of Curcuma Mangga Kombucha: The Effect of Fermentation Duration on Activity Against Escherichia coli and Salmonella typhi Ratna, Ratna; Anjani, Gemala; Nur Afifah, Diana; Ayustaningwarno, Fitriyono; Rustanti, Ninik
Medical Laboratory Technology Journal Vol. 11 No. 1 (2025): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i1.636

Abstract

Kombucha is a fermented beverage known for its various health benefits, including antibacterial activity. This study aims to evaluate the antibacterial potential of mango ginger (Curcuma mangga)-based kombucha against Escherichia coli and Salmonella typhi, as well as to analyze the effect of fermentation duration on the physicochemical properties of kombucha. Fermentation was conducted for 5, 7, 10, and 14 days, with total acidity, pH, and antibacterial activity measurements using the well diffusion method. The results showed total acidity increased as fermentation progressed, while pH decreased. Antibacterial tests demonstrated that mango ginger kombucha exhibited inhibitory activity against Escherichia coli and Salmonella typhi, with the largest inhibition zones observed on day 10 of fermentation (8.2 mm for Escherichia coli and 9.2 mm for Salmonella typhi). Although its inhibitory effect was moderate compared to the positive control (ciprofloxacin), these findings suggest the potential of mango ginger kombucha as a functional beverage with antibacterial properties. Further research is needed to identify the active compounds responsible for its antimicrobial activity and to optimize the fermentation process to enhance its effectiveness.
Organoleptic quality and shelf-life of dry noodle from maize flour and fish hydrolysate protein (Mizepi) for emergency food Resti, Nina; Ayustaningwarno , Fitriyono; Anjani, Gemala; Syauqy, Ahmad; Nuryanto, Nuryanto; Chasanah, Ekowati; Purwani, Endang Yuli; Afifah, Diana Nur
jurnal1 VOLUME 8 ISSUE 1, JUNE 2025
Publisher : Hasanuddin University Food Science and Technology Study Program

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/canrea.v8i1.1262

Abstract

Natural disasters have crucial impacts on food aspects. This problem can be addressed by innovations in nutrient-dense products. However, the reality is that innovation in emergency food products is still minimal, especially in those with high protein content. This research created Mizepi products made from maize flour and Fish Protein Hydrolysate (FPH) for existing emergency food requirements. This organoleptic quality research was conducted on 112 consumer panelists with seven formulations of Mizepi and compared them with maize flour and FPH in grams such as F1 (1:1), F2 (4:7), F3 (4:11), F4 (7:4), F5 (7:11), F6 (11:4), and F7 (11:7) using the Hedonic Test and Just About Right (JAR) on nine scales. Selection of the best formulation was analyzed using the Effectiveness Index Test method. The shelf life test was carried out on the best formulation, namely F4 using the Accelerated Shelf-Life Testing (ASLT) method at temperatures of 35 oC, 45 oC and 50 oC respectively. Samples were observed every 7 days for 28 days. Parameters using water content and Free Fatty Acid (FFA). The organoleptic quality test with hedonic test explained that the product with the most preferred categories is in terms of aroma (F6), color (F1), texture (F4), flavor (F6 and F4), and overall (F4). The most favorable JAR test results for color of all samples were the same, namely yellow, savoriness (F4 and F6), typical savory aroma of corn (F5, F6, F7), typical savory aroma of fish (F3), and crunchy texture (F4). Test results for the shelf life of Mizepi products in the best formulation can be stored well for 46 days at a temperature of 35 oC with water content parameters. The best formulation of F4 meets emergency food requirements, namely it is acceptable in terms of taste, and acceptable.
Co-Authors Abyyudha, Dany Adriyan Pramono Agustina, Ayu Widiawati Ahmad Syauqy Ahmad Syauqy Ahmad Syauqy Ahmad Zulfa Juniarto Aleda Florince Oyay Amin Husni Anang M Legowo Anggray Duvita W Anggriany, Nissa Ani Margawati Ariani Ariani Ayu Rahadiyanti Ayu, Azzahra Mutiara Ayustaningwarno , Fitriyono Binar Panunggal Bintang, Francisca Natalia Christanto, Monica Lemuela Claradhita Ayu Shauma Denny Nugroho Sugianto Deny Yudi Fitranti Dewi Marfu'ah Kurniawati Diana Nur Afifah Diana Nur Afifah, Diana Nur Dwi Ratna Sari Edward Kurnia Setiawan Limijadi Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ekowati Chasanah Endang Mahati Endang Mahati Endang Mahati Endang Sri Lestari Endang Sri Lestari Endang Yuli Purwani, Endang Yuli Enny Probosari Etika Ratna Noer Faizah Fulyani Fatih Az Zahra Fitriyono Ayustaningwarno Fulyani, Faizah Furkaniaty, Annisa Galuh Dwi Astuti Gunawan, Sekar Ayu Putri Hardhono Susanto Hartanti Sandi Wijayanti Hastuti, Vivilia Niken Hunaefi, Dase Indrastati, Nandia Indriyanti, Risa Ivena Claresta Jaeri, Santoso Jalasena, Rizka Akbar Juwita, Riza Iska Kis Djamiatun Kusmiyati Tjahjono Kusmiyati Tjahjono Lili Nor Indah Sari Lubis, Syahrani Aulia MADE ASTAWAN Mambaya, Helvi Desi Maulana, Reza Achmad Miftahul Adnan Millah, Shoffyyatul Mira Dian Naufalina Mohammad Sulchan Mohammad Zen Rahfiludin Muchlis Achsan Udji Sofro Muchlis Achsan. Udji Sufro Mumpuni, Ocka Febrian Muniroh, Muflihatul Nafisah Nani Maharani Nani Maharani Nareswara, Anastu Regita Ninik Rustanti Ninik Rustanti Ninik Rustanti Nur Afifah, Diana Nur Faizah Nurdin, Nurhanifah Muthmainnah Nurmasari Widyastuti Nuryanto Nuryanto Pramesti, Yuli Prasetyo, Dwi Yanuar Budi Pristina Adi Rachmawati Putut Har Riyadi Rachma Purwanti Rafika, Muhana Rahayu, Gita Riski Rahmawati, Irma Sarita Rahmawati, Siti Irma Ratna Ratna Rena Budiyatri Resti, Nina Retnaningsih Retnaningsih Rimadhani Ulfa Rohmatul Ummah S Fatimah Muis Setyawati, Amalia Rani Sherlin Regina Jami Siti Fatimah Muis Siti Fatimah-Muis Siti Fatimah-Muis Sofro, Muchlis AU Sumardi Widodo Sylvia Rahmi Putri Tasya Safira Meliasari Tiffany Nisa Arviyani Tri Winarni Agustini Untari Utama, Affini Nurratri Utami, Wahyu Widyasari Velicia, Velicia Welresna Juliatri Putri Rupiasa Widya, Fiona Christina Zhu, Fan