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The Effect of Administration Ginger and Lemongrass Drink on Interleukine 6 Football Player After Exercise adnan, Miftahul; Afifah, Diana Nur; Anjani, Gemala; Susanto, Hardhono; Noer, Etika Ratna; Widodo, Sumardi
Journal of Sport Science and Fitness Vol. 10 No. 2 (2024): Journal of Sport Science and Fitness
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jssf.v10i2.15662

Abstract

Physical exercise can increase the production of free radicals. Free radical can trigger oxidative stress and inflammation. Ginger and lemongrass has bioactive compound that function as antioxidant and antiinflammatory. This study aim to determine the effecs of giving ginger and lemongras drink on IL6 level in football player. Quasi experimental study with pre and post control group design. The subject were 24 football player divided 2 namely control and intervention group. The intervention group given a ginger and lemongrass drink. The control group was only given brown sugar drink. The intervention are given after exercise for 28 days. Blood samples were collected and tested after exercise. Interleukine 6 were measured using the ELISA Method. Our result showed there was differences in interleukine 6 after giving ginger and lemongrass drink (p=0.004). The delta of interleukine 6 level after intervention was 3.24 pg/ml. Conclusion this research are there was a decrease in interleukine 6 level after giving ginger and lemongrass drink for 28 days to football players after exercise.
A REVIEW OF NON-SOY TEMPEH AND POTENTIAL BENEFITS IN METABOLIC SYNDROME Nafisah, Nafisah; Anjani, Gemala; Afifah, Diana Nur
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 9, No 2 (2024): September
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v9i2.2772

Abstract

Metabolic syndrome is a medical condition that can occur due to various factors such as obesity, lack of physical activity, and genetic factors, and can lead to metabolic disorders. It can cause insulin resistance, high levels of triglycerides, low levels of high-density lipoprotein (HDL), high blood glucose levels, hypertension, and central obesity. One way to manage metabolic syndrome is through food interventions that have hypocholesterolemic effects, such as tempeh. This narrative review delves into the potential benefits of tempeh made from raw materials other than soybeans for metabolic syndrome disease. The review analyzed 13 original research articles published in the last sixteen years from Google Scholar, PubMed, and Science Direct. The findings suggest that tempeh made from non-soy ingredients like moringa seeds, quinoa seeds, barley seeds, fava beans, chickpeas, lotus seeds, and sorghum seeds contain bioactive components and nutritional content that can help reduce cholesterol levels, inflammation, oxidative stress, and blood pressure. Therefore, tempeh made from non-soy ingredients can be used as a functional food and nutraceutical to help improve the condition of metabolic syndrome. Further research on experimental animals is necessary to identify the effectiveness and mechanisms of non-soy tempeh at the molecular level against metabolic syndrome diseases.
Determinant factors influencing the nutrition status of adolescents with intellectual disabilities: a scoping review Suwito, Maria Rebecca; Widyastuti, Nurmasari; Rahadiyanti, Ayu; Anjani, Gemala; Nurhidayati, Lisa Rosyida
BKM Public Health and Community Medicine Vol 41 No 10 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v41i10.19257

Abstract

Purpose: This scoping review aims to explore the determinants influencing the nutritional status of adolescents with intellectual disabilities, including macronutrient intake, family income, and other contributing factors. Methods: A systematic search was conducted for articles published from 2012 to 2022 in PubMed, ScienceDirect, and Scopus databases, using keywords such as "nutritional status," "dietary intake," "family income," "intellectual disability," and "adolescent". Relevant studies were selected through title and abstract screening, followed by full-text review, resulting in nine articles for analysis. Results: The review found that inadequate dietary intake, particularly high consumption of unhealthy foods, significantly impacts the nutritional status of adolescents with intellectual disabilities. Family income, while affecting food security, does not independently determine dietary outcomes. Comorbid conditions like Down syndrome, autism spectrum disorder (ASD), and cerebral palsy, along with physical limitations and the use of psychotropic medications, further contribute to malnutrition risks. Conclusion: Adolescents with intellectual disabilities are at increased risk of malnutrition due to poor food intake. While family income influences food security, it is not the sole factor. The presence of comorbid conditions, physical limitations, and psychotropic medication use is also a key determinant of their nutritional status.
Liprotide-encapsulated vitamin D3 modulates circulated PTH levels and improved bone microstructure Shauma, Claradhita Ayu; Fulyani, Faizah; Pramono, Adriyan; Mahati, Endang; Putri, Sylvia Rahmi; Maulana, Reza Achmad; Anjani, Gemala
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 12, No 1 (2023): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.12.1.44-52

Abstract

Background: vitamin D (25(OH)D) is a fat-soluble vitamin that is unstable in the gastrointestinal environment and has low bioavailability. A protein-lipid complex (liprotide) can be used as a shell to increase vitamin D stability and bioavailability. Liprotide can also serve as a delivery system for transporting vitamin D to its intended site. Little attention has been paid to utilizing liprotide as a delivery system for vitamin D and evaluating its functional activity.Objective: to investigate the effect of liprotide-encapsulated vitamin D3 on PTH levels and bone microstructure in vitamin D and calcium (VD-Ca) deficient rats.Materials and Methods: an overall of 24 Wistar rats had been divided into four groups, a normal control group (K), a VD-Ca group without treatment (K-), a VD-Ca group with 180 IU/200 gBW/day free vitamin D3 (FVD3), and a VD-Ca group with 180 IU/200 gBW/day liprotide-encapsulated vitamin D3 (LVD3). Before and after 28 days of vitamin D intervention, blood samples were taken and analysed for serum PTH levels. The microstructure of the bone was analyzed using the Scanning Electron Microscope (SEM).Results: the VD-Ca rats supplemented with vitamin D3 (FVD3 and LVD3) had a significant decrease in serum PTH levels (p<0.001) and improved bone microstructure (p<0.05) compared to the (K-) group. The reduction of PTH in the LVD3 group was higher compared to the FVD3 group. The bone microstructure between the FVD3 and LVD3 groups is significantly different, as seen in the Ct.Wi parameter, with the LVD3 group having a higher Ct.Wi than the FVD3 group.Conclusion: liprotide-encapsulated vitamin D3 improves the serum PTH level and bone microstructure in a rat model of vitamin D and calcium deficiency.
The Role of Phenolic Compounds as Anti-Inflammatory in Obese Individuals Randenia, Nabila; Noer, Etika Ratna; Anjani, Gemala
Indonesian Journal of Global Health Research Vol 6 No 2 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i2.2682

Abstract

Dietary polyphenols have chemopreventive and protective roles in maintaining human health and disease. Strong antioxidant effects are exhibited by dietary polyphenols and flavonoids against reactive oxygen species (ROS) and cellular oxidative stress (OS), thereby protecting against OS-related pathological conditions or diseases. This study generally aims to see the impact of phenol and bioactive compounds on inflammation in obese individuals. The method used in this study is a literature review. The stages involved in this process encompass identifying the central topic or issue to be discussed, conducting a comprehensive search for pertinent references or literature related to the topic, thoroughly reading, evaluating, and analyzing the literature in alignment with the study objectives, and finally, composing a narrative report that presents the review findings along with a concise summary. The time frame for the analysis was April 2013 to June 2023. A total of 323 publications with phenolic compounds as anti-inflammatory in obese were identified. From the initial 323 studies, 12 studies were selected for final analysis. The search for relevant articles or references will be conducted in the online databases Science Direct, Springer, Wiley Library, PubMed, and Google Scholar. The keywords used to search for references are obesity, inflammation, phenol compounds, bioactive compounds, antioxidants, and antioxidants. This literature review found that out of the 12 articles reviewed, 12 had similarities, stating that interventions with different doses of phenol compounds can reduce inflammatory cytokines in obesity with different periods. Overall, antioxidant bioactive compounds regulate pro-inflammatory and anti-inflammatory cytokines, reduce oxidative stress by decreasing the accumulation of reactive oxygen species, and enhance antioxidant capacity and gene expression to prevent DNA damage in obese individuals.
Formulasi biskuit tepung tempe biji kedawung (Parkia roxburghii G. Don) untuk pasien diabetes melitus Triyanto, Bagaskara Putra; Nugroho, Teddy Wahyu; Widyastuti, Nurmasari; Masruroh, Zulfatul; Anjani, Gemala
Jurnal Gizi Klinik Indonesia Vol 20, No 1 (2023): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.67253

Abstract

Formulations of biscuits from kedawung seed tempeh flour (Parkia roxburghii G. Don) for diabetes mellitus patientsBackground: Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia. Blood glucose can be controlled with food consumption with low glycaemic index (GI) and glycaemic load (GL) values. Kedawung seeds contain high protein and fiber and can be an alternative to low GI and GL food sources for DM patients. Objectives: This research analyzed total protein, crude fiber, glycaemic index, and glycaemic load levels from biscuits by substituting kedawung seed tempeh flour.Methods: The study was an experimental study with four treatments. The substitution of kedawung seed tempeh flour in biscuits was 0%, 10%, 30%, and 50%. Protein content was analyzed using the Kjeldahl method, and crude fiber was analyzed using the gravimetric method. Statistical analysis was done using the One Way ANOVA and Tukey posthoc test. A hedonic test on 25 semi-trained panelists was conducted to determine the best formulation, and the results were analyzed using the Kruskal Walls and Friedman post-hoc test. IAUC analyzed the glycaemic index from 10 respondents. Results: Biscuits substituting kedawung seed tempe flour affected protein content (p=0.00) and crude fiber (p=0.00). The best acceptance was biscuits with a 10% substitution of kedawung seed tempeh flour, which has a 32.28% glycemic index value and a 9.98% glycemic load. Conclusions: The biscuits substituting kedawung seed tempeh flour significantly increased protein and crude fiber content. Biscuit formulation with 10% kedawung seed tempeh flour had a low glycemic index and glycemic load.
Co-Authors Abyyudha, Dany Adriyan Pramono Agustina, Ayu Widiawati Ahmad Syauqy Ahmad Syauqy Ahmad Syauqy Ahmad Zulfa Juniarto Aleda Florince Oyay Amin Husni Anang M Legowo Anggray Duvita W Anggriany, Nissa Ani Margawati Ariani Ariani Ayu Rahadiyanti Ayu, Azzahra Mutiara Ayustaningwarno , Fitriyono Binar Panunggal Bintang, Francisca Natalia Christanto, Monica Lemuela Denny Nugroho Sugianto Deny Yudi Fitranti Dewi Marfu'ah Kurniawati Diana Nur Afifah Diana Nur Afifah, Diana Nur Dwi Ratna Sari Edward Kurnia Setiawan Limijadi Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ekowati Chasanah Endang Mahati Endang Mahati Endang Mahati Endang Sri Lestari Endang Sri Lestari Endang Yuli Purwani, Endang Yuli Enny Probosari Etika Ratna Noer Faizah Fulyani Fatih Az Zahra Fitriyono Ayustaningwarno Fulyani, Faizah Furkaniaty, Annisa Galuh Dwi Astuti Gunawan, Sekar Ayu Putri Hardhono Susanto Hartanti Sandi Wijayanti Hastuti, Vivilia Niken Hunaefi, Dase Indrastati, Nandia Indriyanti, Risa Ivena Claresta Jaeri, Santoso Jalasena, Rizka Akbar Juwita, Riza Iska Kis Djamiatun Kusmiyati Tjahjono Kusmiyati Tjahjono Lili Nor Indah Sari Lubis, Syahrani Aulia MADE ASTAWAN Mambaya, Helvi Desi Masruroh, Zulfatul Maulana, Reza Achmad Miftahul Adnan Millah, Shoffyyatul Mira Dian Naufalina Mohammad Sulchan Mohammad Zen Rahfiludin Muchlis Achsan Udji Sofro Muchlis Achsan. Udji Sufro Mumpuni, Ocka Febrian Muniroh, Muflihatul Nafisah Nafisah Nafisah Nani Maharani Nani Maharani Nareswara, Anastu Regita Ninik Rustanti Ninik Rustanti Ninik Rustanti Nur Afifah, Diana Nur Faizah Nurdin, Nurhanifah Muthmainnah Nurhidayati, Lisa Rosyida Nurmasari Widyastuti Nuryanto Nuryanto Pramesti, Yuli Prasetyo, Dwi Yanuar Budi Pristina Adi Rachmawati Putri, Sylvia Rahmi Putut Har Riyadi Rachma Purwanti Rafika, Muhana Rahayu, Gita Riski Rahmawati, Irma Sarita Rahmawati, Siti Irma Randenia, Nabila Ratna Ratna Rena Budiyatri Resti, Nina Retnaningsih Retnaningsih Rimadhani Ulfa Rohmatul Ummah S Fatimah Muis Setyawati, Amalia Rani Shauma, Claradhita Ayu Sherlin Regina Jami Siti Fatimah Muis Siti Fatimah-Muis Siti Fatimah-Muis Sofro, Muchlis AU Sumardi Widodo Suwito, Maria Rebecca Sylvia Rahmi Putri Tasya Safira Meliasari Teddy Wahyu Nugroho, Teddy Wahyu Tiffany Nisa Arviyani Tri Winarni Agustini Triyanto, Bagaskara Putra Untari Utama, Affini Nurratri Utami, Wahyu Widyasari Velicia, Velicia Welresna Juliatri Putri Rupiasa Widya, Fiona Christina Zhu, Fan