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Seprianto, Seprianto
Universitas Esa Unggul
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Effects of Tele-Exercise on Body Composition, Lipid Profile, Mental Health, and SIRT1 Gene Expression in Obese Office Employees in Indonesia Kuswari, Mury; Rimbawan, Rimbawan; Hardinsyah, Hardinsyah; Dewi, Mira; Gifari, Nazhif; Pamungkas, Rian Adi; Seprianto, Seprianto; Himarwan, Aditya; Putra, Felicia Kartawidjaja; Dijaya, Rendy; Subali, Dionysius
Media Gizi Indonesia Vol. 21 No. 1 (2026): MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v21i1.75-89

Abstract

Tele-exercise delivers remote physical activity programs via digital platforms, enhancing accessibility and adherence, making it a promising strategy to address obesity among workers. This study aimed to evaluate the effects of tele-exercise programs on body fat percentage, lipid profile, mental health measures and Sirtuin 1 (SIRT1) gene expression measured via venipuncture & RT-PCR in obese office employees. A total of 33 overweight or obese employees (male/female, 18-45 years old, Body Mass Index (BMI) 23-30 kg/m2) were randomly assigned to the strength (SE) group, strength-cardio (SC) group, and control (CT) group. The strength exercise protocol included core training, circuit training, High Intensity Interval Training (HIIT) and Tabata training; cardio exercise includes low-high impact aerobic exercises. Each group was given nutrition education, whereas the two intervention groups participated in tele-exercise three times/week for twelve weeks. Tele-exercise was delivered via ZOOM application. Mental health indicators were measured using the Depression Anxiety Stress Scale (DASS-42) questionnaire. Compliance levels between intervention groups did not differ significantly (p>0.05). There was a significant reduction in bodyweight in the SC group (p=0.046). Blood High Density Lipoprotein (HDL) levels increased only in the SC group (0.50 mg/dL), but decreased in the SE group and CT group. SIRT1 gene expression increased in SE and CT groups (2.39- and 5.33-fold, respectively), whereas a significant decrease was observed in the SC group (p=0.043). Only the SE group showed a significant reduction in stress level (p=0.03), with a decrease of 30.9%. Strength exercise intervention improves total cholesterol level by -19.09 mg/dL. 
Co-Authors Abda Abda Adelia, Ismi Agustinus Robert Uria alfero Putra Iryanto Alham, Fiddini Anisa Febriyanti Ariyadi, Noprizal Aroem Naroeni Aroem Naroeni Ayu, Yulia Agustina Azwar, Beni callista marsya Chikita, Daien Cyndi Prasetya Daflaini, Daflaini Darwata, Siti Riva DEWI PURNAMA Dewi Seswita Zilda Dewi Seswita Zilda Dewi, Lisa Rahma Dewi, Mustika Sandra Dijaya, Rendy Dina Hajja Ristianti, Dina Hajja Dionysius Subali Effendi, Desy Irafadillah Efriyana oksal Erani, Friska Fadila Fadila, Fadila Fajariyanto, Gunawan Febriana Dwi Wahyuni feby feby Feliatra Gifari, Nazhif Gloria, Meilina Gusvina, Fadilla Hana Nurullita Prestisia Hardinsyah Harna, Harna Hasibuan, Molani Paulina Henny Saraswati Henny Saraswati Himarwan, Aditya Idi Warsah Irfandi, Ahmad Jofrishal Jofrishal Juniyati, Sintia Kevin Febrianus Moda Kibtiyah, Maryatul Lawrence, Yoel Lesmawan, Hendra Mahyuny, Siska Rita Manalu, Mely Grace Manalu Maulida, Maulida Mauliza, Mauliza Muhamad Amza Sidiq Muhammad Arreza Mury Kuswari nie nie Noer Khasanah Noperta, Noperta Nora, Adri Novianti, Titta Nugraha, Jaka Setia Nurmalasari, Mieke Nursanah, Nursanah Ogi Danika Pranata Oktaviani Naulita Turnip Oktaviani, Coryna PUSPITA LISDIYANTI Puspita Lisdiyanti Putra, Felicia Kartawidjaja PUTRI HANDAYANI Putri Handayani putri mega utami Putri, Mentari Darma Rahmah, Rasya Aulia Rahmayanti R, Andi Rian Adi Pamungkas Riansyah, Irza Rimbawan , Rini Hidayati Rini Hidayati roaslein putri Roaslein Putri Roselein Putri Ruhmayanti, Nur Ayu Sa'pang, Mertien Sabar Pambudi Saraswati, Henny Saraswati, Henny Sari, Ratih Permana Seda, Ananda Putri Sianturi, Dody Jhonatan Wilfiez Sidauruk, Christina Siti Komariyah Situmorang, Larissa Kristina T.T. Soleha, Sovatunisa Suharsono Suharsono Surgasari, Tania Susanti, Sela Syamsul Rizal Titania Tjandrawati Nugroho Veza Azteria Widodo Widodo Wiriatmaja, Nuraini Ulya Yusro Nuri Fawzya Yusro Nuri Fawzya Zadrax, Adellino Zhafira, Alipya