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All Journal Majalah Kedokteran Bandung Medula Juke Jurnal Kesehatan JURNAL ILMIAH KESEHATAN SANDI HUSADA Bioscientia Medicina : Journal of Biomedicine and Translational Research JURNAL PENELITIAN PERAWAT PROFESIONAL JK Unila (Jurnal Kedokteran Universitas Lampung) Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Nursing and Health Sciences (IJNHS) Majority Jurnal Ilmiah Kesehatan Sandi Husada JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Rizki Hanriko
Universitas Lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Hubungan Antara Hipertensi dan Usia dengan Angka Kejadian Kanker Payudara Di RSUD Dr. H. Abdul Moeloek Bandar Lampung Tahun 2018 Mohamad Reihansyah Deswindra; Muhartono; Rizki Hanriko; Waluyo Rudiyanto
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.12

Abstract

Breast cancer is one of the most highest incidence rate cancer in all countries. Age and Hypertension is known as risk factor for breast cancer. The purpose of this study is to know the relation between hypertension and age with breast cancer incidence rates in Dr. H. Abdul Moeloek Bandar Lampung. The method of this study is observational analytic study with case control design. The data that used are secondary data that gathered from medical records of patients in Dr. H. Abdul Moeloek Hospital and taken with consecutive sampling method. The data is analyzed using univariate and bivariate analysis using Chi-square test and Fisher test. The result is in the case group, hypertension percentage obtained was 12.5% ​​while those whose has not hypertension was 87.5%. In the control group the percentage of hypertension was 8.3% while those whose has not hypertension was 91.7%. In the case group ≥50 years of age percentage obtained was 54.2% while at age <50 years was 45.8%. In the control group ≥50 years of age percentage of 16.7% while at age <50 years at 83.3%. The results showed that age ≥50 years have a p value = 0,007 with OR = 5,909 and hypertension group have a p value = 0.500. The conclusion of this study is, there is no the relationship between hypertension and breast cancer incidence rates Lampung and there is relationship between the age of patients with breast cancer incidence rates in the Hospital of Dr. H. Abdul Moeloek Bandar Lampung.
Pengaruh Pemberian Ekstrak Etanol Rimpang Lengkuas (Alpinia galanga) terhadap Gambaran Histopatologi Testis Mencit (Mus musculus L.) jantan yang Diinduksi Monosodium Glutamat Annisa Shafira Pramono; Muhartono; Rizki Hanriko; Eca Cania
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.43

Abstract

Monosodium Glutamate (MSG) may form free radicals that cause damages to the organs of the body, one of which is the male reproductive organs, i.e. testes. Galangal rhizome is one of the natural ingredients with antioxidant content that can neutralize free radicals. The purpose of this research was to determine the effect of ethanol extract of galangal rhizome on testicular histopathology of MSG-induced male mice. The design of this research was experimental research with 5 treatment groups, each group consisted of 5 mice (Mus musculus L.) DDY strain. Group K (-) was not treated; k (+) was provided with 4 mg/ grBB MSG; P1 was provided with 4 mg/ grBB MSG + 14 mg/ 20 grBB ethanol extract of galangal rhizome; P2 was provided with 4 mg/ grBB MSG + 28 mg/ 20 grBB ethanol extract of galangal rhizome; P3 was provided with 4 mg/ grBB MSG + 56 mg/ 20 grBB ethanol extract of galangal rhizome. Assessment used Johnsen score in group K(-) was 48,4, K(+) was 47,4, P1 was 47,4, P2 was 47,4, and P3 was 48. Kruskal-Wallis test result was p=0,085 (p>0,05). The conclusion was that ethanol extract of galangal rhizome did not effect significantly (p>0,05) on the testicular histopathology of monosodium glutamate-induced mice.
Efek Curcumin Sebagai Pengobatan Penyakit Jantung Koroner Anggun Elidiya; Rizki Hanriko; M. Yusran
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.264

Abstract

Atherosclerosis is a chronic and progressive problem due to the inflammatory response, oxidative stress (OS), lipid deregulation, and epigenetic disorders. Curcumin is the main compound in turmeric and is responsible for turmeric yellow and contains 50% of turmeric. Curcumin has a hypolipidemic effect along with antioxidant and anti-inflammatory, it can contribute to reduce the incidence of atherosclerosis. The extraordinary antioxidant content of curcumin reduces lipid peroxidation and oxLDL formation, and consequently, reduces the inflammatory response and the development of atherosclerosis. Another study shows that curcumin can alter gene expression associated with leukocyte adhesion and transendothelial migration in aortic tissue by increasing expression of NF-κB protein inhibitors (IκB) and decreasing NF-κB bonds and transcription activity after stimulation with tumor necrosis factor-α (TNF-α). In addition, it is proven that curcumin can regulate the activation of toll-like receptor 4 (TLR4), a receptor that recognizes exogenous or endogenous molecular patterns and modulates immune and inflammatory responses. The role of other curcumin for atherosclerosis is smooth muscle cell proliferation. Curcumin is an antioxidant that can be one of the management of coronary heart disease due to be able to suppress the formation of atherosclerosis and reduce cholesterol levels in the blood. It is expected that curcumin can be the first treatment for coronary heart disease.
Hububgan Hubungan Riwayat Merokok, Konsumsi Alkohol dan Diabetes dengan Derajat Histopatologi Karsinoma Kolorektal di RSUD Dr. H. Abdul Moeloek Bandar Lampung Periode 2017-2018 Gede Ardi Saputra; Rizki Hanriko; Hendri Busman; Muhartono
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.154

Abstract

Colorectal carcinoma is a malignant neoplasm which originating or growing in the colon or rectum. Colorectal carcinoma is one of the 10 most common cancers suffered by Indonesians. Carcinomas develop much less in the duodenum, jejunum, and ileum than in the colon and rectum. The duodenum, jejunum, and ileum join the colon in the lower right abdomen. In the early stages most cancers do not show any particular clinical symptoms, however, early testing can minimize a poor prognosis. Screening or screening for colorectal carcinoma can be performed in groups of men and women over 50 years of age or patients who are at risk of developing colorectal carcinoma. Screening should also be done by people with polyps or individuals at risk of other carcinomas. The purpose of this study was to determine the frequen distribution and the relationship between smoking history, alcohol consumption history and diabetes history to the histopathological degree of colorectal carcinoma in RSUD Dr. H. Abdul Moeloek. This research was conducted in October-November 2019 at Dr. H. Abdul Moeloek Bandar Lampung using the observational method. The sample of this study consisted of 94 people with medical record data determined using total sampling techniques. Data were processed using statistical tests with a confidence level of 0.05. Chi-square test results showed that there is a  correlation between smoking history (p = 0.0008), alcohol consumption (p = 0.006) and diabetes mellitus (p = 0.015) with the histopathological degree of colorectal carcinoma. So, it can be concluded there is a correlation between smoking history, alcohol consumption and diabetes.
Pengaruh Pemberian Ekstrak Teh Hijau (Cammelia Sinensis) Terhadap Gambaran Histopatologi Silia Pada Trakea Tikus Putih Jantan Galur Sprague Dawley yang Dipapar Uap Rokok Elektronik Ahmad Syah Putra; Susianti; Rizki Hanriko
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.156

Abstract

At present, there is a shift in the use of cigarettes, from conventional cigarettes to e-cigarettes. Exposure to particulate e-cigarettes can cause damage to the airway, one of which is ciliary tracheal. Green tea (Camellia sinensis) has a source of antioxidants in the form of polyphenols which can reduce the number of organ damage through a mechanism as an anti-oxidant. The study used an experimental design using 30 Sprague Dawley strain white rats which were divided into 6 groups, namely 3 control groups and 3 treatment groups. In the control group, given regular treatment, exposure to electric cigarettes and exposure to conventional cigarettes. In the treatment group, mice were given peritoneal injection of green tea extract each of 50 mg/kg body weight, 100 mg/kg body weight, and 200 mg/kg body weight. After 14 days of treatment, the 15th day of mice was euthanized and preparations were taken. There was a change in histopathological damage in all samples where there were significant differences in the control group, but not significantly in the treatment group with a value of K1 to K2 with p = 0.005, and K1 to K3 with p = 0.007. Whereas in vape control group (K2) between treatment groups P1, P2, and P3 were p = 0.521.There is not difference between the administration of green tea extract to histological ch es in cilia’s tracheal structure of rats exposed to steam electronic cigarettes with p=0,521.
Faktor Risiko Kanker Kolorektal Naufal Rasyid Aswan; Rizki Hanriko
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.560

Abstract

Colorectal cancer is cancer of the colon or rectum. Colorectal cancer is the third most common cancer in men and second in women, and according to data from the World Health Organization (WHO), colorectal cancer accounts for nearly 1.4 million new cases every year worldwide. In 2017, there were 1.8 million cases of colorectal cancer worldwide, with a standard incidence rate of 23.2 cases per 100,000 person-years. This article is a literature compiled to analyze the risk factors associated with colorectal events. The references used are articles published between 2012-2022. Colorectal cancer risk factors are divided into modifiable risk factors and non-modifiable risk factors. The most dominant non-modifiable risk factor is a history of IBD, followed by a family history of cancer, history of diabetes, age and gender. The most dominant modifiable risk factor is psychosocial stress, followed by alcohol consumption, smoking history, and obesity.
MIASTENIA GRAVIS: ETIOLOGI, PATOFISIOLOGI, MANIFESTASI KLINIS, PENEGAKKAN DIAGNOSIS DAN TATALAKSANA KHAIRUNNISA SALSABILA; Hanna Mutiara; Rizki Hanriko
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.598

Abstract

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating weakness of the extraocular, bulbar, and proximal muscles. Muscle weakness that occurs will worsen with activity and improve after rest. Myasthenia gravis is caused by the presence of autoantibodies on the postsynaptic membrane at the neuromuscular-junction (NMJ), such as antibodies against acetylcholine receptors, MuSK and LRP4. Myasthenia gravis is a rare neurological disease, the incidence is only about 1.7-21.3 per 1,000,000, has a bimodal distribution in women, with a peak of incidence at the age of 30-50 years. Men have a higher proportion after age 50. Myasthenia gravis is mostly a treatable disease but can result in significant morbidity and even death, so writing this literature review aims to discuss the pathophysiology, clinical manifestations, diagnosis and current treatment options for MG so as to increase the accuracy of the very early diagnosis. plays an important role in early management, as well as prevention of worse disease progression. The diagnosis of MG is based on anamnesis, neurological examination, electrodiagnostics, serology, and CT scan of the chest to see the presence of thymoma. The main treatment for MG is cholinesterase enzyme inhibitors and immunosuppressive agents. Symptoms that are resistant to primary treatment modalities or that require rapid resolution, such as in a myasthenic crisis, may require plasmapheresis or intravenous immunoglobulin treatment. Thymectomy can also be done.
DAMPAK PEMBELAJARAN ONLINE TERHADAP KESEHATAN MENTAL PADA ERA PANDEMI COVID-19: DAMPAK PEMBELAJARAN ONLINE TERHADAP KESEHATAN MENTAL PADA ERA PANDEMI COVID-19 Okki Muhammad Fajar Muthahhari; Rani Himayani; Rizki Hanriko
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.784

Abstract

COVID-19, which spread throughout the world, causing the disease to be declared a pandemic, has affected all aspects of people's lives without exception in the world of education, which was previously conducted face-to-face, now the learning method has changed to online learning. This causes many things to be done by using communication tools as a socializing chain with the surrounding environment. Online education is a new method of learning through networks that has been in place since early 2020, which is one of the steps to reduce the spread of COVID-19. Distance Education can have an impact on students' psychology. This causes many things to be done by using communication tools as a socializing chain with the surrounding environment. Mental health is becoming a problem in the midst of the COVID-19 pandemic, especially for elementary school students. Mental health is constantly changing, creating a variety of major problems that must be resolved. This article aims to determine the mental health of students while undergoing online learning during the COVID-19 pandemic era. The type of review used in this journal is in the form of a literature review of 40 articles found through the NCBI database, PubMed, Google Scholar, only 22 articles were selected from 2020 to 2022. The result of this article is to explain the latest updates regarding the impact of online learning in the era of the COVID-19 pandemic. 19 on mental health.
Faktor-Faktor yang Mempengaruhi Derajat Kecacatan Kusta Fauziani, Andra Nabila; Anggraini, Dwi Indria; Hanriko, Rizki; Sibero, Hendra Tarigan
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.936

Abstract

Morbus Hansen, also known as leprosy, is an infectious disease that is chronic or chronic. This disease is caused by the acid-fast bacillus (BTA) Mycobacterium leprae which is obligate intracellular. This disease can attack various body systems, including the peripheral nervous system, skin, mucosa, upper respiratory tract, reticuloendothelial system, eyes, muscles and bones. Based on WHO data for 2021, globally there were 133,781 cases of leprosy, with Indonesia ranking third highest in the world with 10,976 new cases after India and Brazil. Leprosy that is not treated properly can cause disability. There are two types of disability in leprosy, namely primary and secondary disability. Primary disability is caused directly by the Mycobacterium leprae bacteria, while secondary disability is a disorder that arises because the primary disability is not treated properly. The level of disability in leprosy is classified based on symptoms of damage to the eyes, hands and feet with levels 0, 1 and 2. Factors that influence the degree of disability in leprosy are grouped into demographic factors, internal factors and external factors. Demographic factors include age, gender, socio-economic status, occupation, and education level. Internal factors include the type of leprosy, length of suffering, number of nerves affected, and leprosy reaction. External factors include compliance with taking medication, delays in treatment, and self-care.
Literature Review : Tatalaksana Mioma Uteri Fatahillah, Fatahillah; Hanriko, Rizki; Septiani, Linda; Sari, Ratna Dewi Puspita
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.996

Abstract

Myoma or uterine fibroids are benign tumors that often occur in the uterine wall. Myomas can be asymptomatic or cause symptoms such as abnormal bleeding, pelvic pain, and disorders of the urinary tract. Risk factors include age, race, age of menarche, parity, family history, hormonal contraceptive use, and obesity. Diagnostic examination involves pelvic examination, ultrasound, hysteroscopy, and MRI. Medical therapies used such as NSAIDs, oral contraceptives, Levonorgestrel-releasing intrauterine system (Mirena), tranexamic acid (cyclocapron), GnRH agonists and SPRMs and surgeries such as myomectomy, hysterectomy, uterine artery embolization, and MRgFUS. Management of Myoma must consider various factors, namely tumor size, patient age, symptom and the desire to maintain fertility in order to provide optimal treatment according to the patient's needs and preferences.
Co-Authors - Muhartono - Muhartono Ade Yonata Ahmad Syah Putra Alif Fernanda Putra Anggraeni Janar Wulan, Anggraeni Janar Anggun Elidiya Annisa Shafira Pramono ari wahyuni Ari Wahyuni Baehaqi Bella Pratiwi Anzani Betta Kurniawan, Betta Dewi Nur Fiana Dian Isti Angraini Dian Isti Angraini Diana Mayasari Dwi Indria Anggraini Dyah Wulan Sumekar Rengganis Wardani Eca Cania Ety Apriliana Ety Apriliana Exsa Hadibrata Fadly, Ahmad Aulia Fatahillah, Fatahillah Fauziani, Andra Nabila Fauziyyah Nuur Al azizah Fidha Ramayani Gede Ardi Saputra Hadibrata, Exsa Hamidi, Syahrul Hanarisha Putri Azkia Hanna Mutiara Haryani Dwita Haula Rizqiyah Helsa Apty Tamara Hendra Tarigan Sibero Hendri Busman Indri Windarti Intanri Kurniati Jhons Fatriyadi Suwandi Johns Fatriyadi Suwandi Khairun Nisa KHAIRUNNISA SALSABILA Liana Sidharti Lukman Pura M. Ricky Ramadhian M. Ridho Ulya M. Yusran Meriska Cesia Putri Mohamad Reihansyah Deswindra Muhammad Iz Zuddin Adha Muhartono Muhartono Muhartono Muhartono Muhartono Muhartono Muhartono Muhartono Mukhlis Imanto, Mukhlis Nabil Abdurrahman Nailul Azizah Naufal Rasyid Aswan Naufal Rasyid Aswan Neza Ukhalima Hafia Sudrajat Nisa Karima Nora Ramkita Nurul Islamy Okki Muhammad Fajar Muthahhari Oktadoni Saputra, Oktadoni Oktafany, Oktafany Pairulsyah Pairulsyah Panca Bayu Prabowo, Arif Yudho Putu Devie Sri Astari Rahmayani, Fidha Ramadhan Triyandi Rani Himayani Ratna Dewi PS Ratna Dewi Puspita Sari Retno Ariza Soeprihatini Rinaldy, Dino Risal Wintoko Risal Wintoko Riska Wulandari Riyan Wahyudo Rodiani Rodiani, Rodiani Roro Rukmi Windi Perdani, Roro Rukmi Rudiyanto, Waluyo Septiani, Linda Sezia Marina Siti Raqiya Rasyid Sri Janahtul Hayati Suharmanto Suharyani Sulinawati Sulinawati Suryadi Islami Susianti Susianti Susianti Susianti, Susianti Syahrul Hamidi Nasution Tarrinni Inastyarikusuma Tasya Khalis Ilmiani Tri Umiana Soleha Tri Umiana Soleha Trixie Almira Uliana Nur Melin Veny Anisya Waluyo Rudiyanto Widya Pebryanti Manurung Wulan, Anggraini Janar Yovani Rehuel Br Sitepu