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All Journal Medula Juke Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya JURNAL ILMIAH KESEHATAN SANDI HUSADA JK Unila (Jurnal Kedokteran Universitas Lampung) Nusantara Hasana Journal International Journal of Advanced Health Science and Technology International Journal of Health, Engineering and Technology Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Majority Jurnal Ilmiah Kesehatan Sandi Husada Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Dian Isti Angraini
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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PENGARUH KONSUMSI SERAT TERHADAP PROFIL LIPID DAN PENANDA INFLAMASI: TINJAUAN LITERATUR Simanjuntak, David Bryan Natanael; Dian Isti Angraini; Hesti Yuningrum; Dwita Oktaria
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1814

Abstract

Cardiometabolic diseases are a leading cause of global morbidity and mortality, with dyslipidemia and chronic low-grade inflammation playing key pathophysiological roles. Dietary factors, particularly dietary fiber intake, represent modifiable risk factors. This literature review aimed to evaluate the effects of dietary fiber consumption on lipid profiles and inflammatory markers. A systematic literature search was conducted using PubMed and Scopus with keywords related to dietary fiber, lipid profile, and inflammation. Of 157 identified articles, 8 met the inclusion criteria and were included in the analysis. The findings indicate that dietary fiber intake, especially soluble fiber, is consistently associated with reductions in total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglyceride levels, particularly among individuals with type 2 diabetes mellitus, hyperlipidemia, and metabolic syndrome. In contrast, the effect of fiber on increasing high-density lipoprotein (HDL) cholesterol remains limited and inconsistent. Regarding inflammation, fiber consumption shows a more consistent anti-inflammatory effect on C-reactive protein (CRP), whereas its impact on proinflammatory cytokines such as interleukin-6 and tumor necrosis factor-α is variable. These differences may be influenced by fiber type, dosage, intervention duration, and participant characteristics. Overall, dietary fiber may serve as a safe and promising adjunct nutritional strategy for the prevention and management of cardiometabolic diseases.
OBESITAS: ASPEK KLINIS, FAKTOR RISIKO, DAN DAMPAK KESEHATAN Enriko Aprilio; Dian Isti Angraini; Putri Damayanti; Reni Zuraida
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1868

Abstract

Obesity has emerged as one of the most significant global health concerns in recent decades, with its prevalence rising across different age groups and socioeconomic settings. Characterized by excessive accumulation of body fat, obesity disrupts metabolic regulation and substantially increases the risk of chronic diseases such as type 2 diabetes, cardiovascular disorders, liver disease, and various cancers. Recent evidence also highlights the rapid growth of obesity among children and adolescents, indicating long-term health consequences that may appear earlier in adulthood. This literature review examines the clinical aspects of obesity, including its definition, physiological mechanisms, and metabolic characteristics. It also explores the multifactorial risk factors associated with obesity, encompassing genetic predisposition, lifestyle patterns, socioeconomic conditions, and environmental influences. Furthermore, the review discusses the broad health impacts of obesity, ranging from metabolic and cardiovascular complications to psychological outcomes and intergenerational risks. The findings emphasize the need for comprehensive preventive and management strategies that integrate public health approaches, behavioral interventions, and supportive health policies to address the increasing burden of obesity at both individual and population levels.
Co-Authors Agustyas Tjiptaningrum Ahmad Alvin Dictara Aila Karyus Alvin Widya Ananda Ananda Felicia Aziza Andrian Reza Saputra Anggraeni Janar Wulan Anisa Nuraisa Jausal Arilinia Pratiwi Asiah Nurul Izzah Ayu Agustira Bagus Pratama Betta Kurniawan, Betta Clara FIrhan Asifa Claudia Clara Delisa Mutiara Nabila Diana Mayasari Dwita Oktaria Dyah Wulan Sumekar RW Efriyan Imantika Enriko Aprilio Fauzia Tria Andara Sari Febilla Naili Alfalah Fernanda Kusumawardani Fitria Saftarina Habibi Adhi Pratama Duarsa Haliza Henfa Dela Cruz Hana Nafisah Hesti Yuningrum Intanri Kurniati Iswandi Darwis Itsa, Nando Abdila Izzah, Asiah Nurul Jhons Fatriyadi Suwandi Khairun Nisa Khairun Nisa Kurnia Eka Putri Linda Septiani M. Agung Prasetya Adnyana Yoga M. Nabil Sulthoni Eralsyah Meriska Cesia Putri Minerva Nadia Muhammad Aditya Muhammad Muizzulatif Mutiara Kartiko Putri Nadia Rosmalia Dewi Nayarani Humaira Oktadoni Saputra Oktafany Pinkan Ahdalifa Putri Damayanti Putu Ristyaning Ayu Rachmi L.P. Rukmono Rachmi Lestari Rukmono Ramadhana Komala Ratna Dewi Puspita Sari Ratu Henggar Audrya Gharrieni Reni Zuraida Renti Kusumaningrum Samosir Rika Lisiswanti Rizki Arisandi Rizki Hanriko Rojwa Azka Syakira Sartika Safitri Septyne Rahayuni Putri Simanjuntak, David Bryan Natanael Sofyan Musyabiq Wijaya Soraya Rahmanisa Sumayyah Annida Syfa Dinia Putri TA Larasati Tasya Khalis Ilmiani Terza Afika Happy Tri Umiana Soleha Triola Fitria Uliana Nur Melin Winda Puspita Sari Zahira Farini Hasbani Zulfa Labibah