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PENGARUH PEMBERIAN BUBUK EKSTRAK CU-TURUNAN KLOROFIL DAUN CINCAU (Premna oblongijolia Merr.) TERHADAP PROFIL LIPID DARAH KELINCI Nurdin Nurdin; Ali Khomsan; Sri Anna Marliyati; Faisal Anwar; Clara Meliyanti Kusharto; Dewi Ratih Agungpriyono
Media Gizi dan Keluarga Vol. 32 No. 1 (2008): Media Gizi dan Keluarga
Publisher : Media Gizi dan Keluarga

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Abstract

ABSTRACT. The aim of this research was to produce cincau copper-derivative chlorophyll powder and to observe its phYSico-chemical properties and the effect on blood lipid profile of5 month male New Zealand White rabbits. The blood lipid profile observed were total cholesterol, triglyceride, HDL (high-denSity lipoprotein) cholesterol, and LDL (low-density lipoprotein) cholesterol. A two months treatment was conducted A randomblock design was applied with the following treatment on each experimental unit: PO (basal diet, negative control), PI (basal diet with cholesterol 0.1% (wlw) added, positive control), P2 (basal diet with cholesterol 0.1% (wlw) and 16.7 mglkg-body weight/d natural chlorophyll powder added), P3 (basal diet with cholesterol 0.1% (wlw) and 16.7 mglkgbody weight/d copper-derivative of chlorophyll powder added), P4 (basal diet withcholesterol 0.1% (wlw) and 50.1 mglkg-body weightld copper-derivative of chlorophyll powder added}, P5 (basal diet with cholesterol 0.1% (wlw), and 16.7 mglkg-body weight/dcommercial chlorophyll powder added The results of study showed that cincau leaves chlorophyll extract solution with Cu1+ 100 mglL level produce the cincau copper-derivate chlorophyll powder with highest pH, solubility, and greenness compared to other copper levels. Feeding with copper-derivative of chlorophyll cincau powder (P3) most likely decreased total cholesterol, triglycerides, LDL cholesterol increased the HDL cholesterol,and decreased atherosclerosis risk after 2 month as compare to feeding contain of natural chlorophyll (P2). Keywords: Premna oblongifolia Merr., copper-derivate chlorophyll powder, totalcholesterol, triglyceride. HDL cholesterol, LDL cholesterol
PENILAIAN KROMIUM SERUM DARAH PADA PENYANDANG DIABETES MELLITUS TIPE 2 DAN NON DIABETES Susi Nurohmi; Rimbawan Rimbawan; Faisal Anwar; Adi Teruna Efendi
Media Kesehatan Masyarakat Indonesia Vol. 12 No. 4: DESEMBER 2016
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (304.532 KB) | DOI: 10.30597/mkmi.v12i4.1547

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Diabetes mellitus tipe 2 merupakan salah satu masalah kesehatan dunia. Berdasarkan survei Riskesdas 2013, prevalensi dari diabetes melitus tipe 2 di Indonesia pada usia 15 tahun atau lebih adalah 6.9%. Prevalensiyang tinggi dapat dipicu oleh diet yang kurang sehat dan rendahnya aktivitas fisik. Kromium dalam hal ini sebagai mineral mikro yang memiliki peran dalam menjaga homeostasis glukosa darah diduga memiliki fungsi dalam meningkatkan respon insulin. Penelitan ini bertujuan mengetahui hubungan antara aktivitas fisik, tingkat kecukupan energi dan zat gizi, dengan kadar glukosa darah puasa dan HbA1c. Desain penelitian ini adalah survei potong lintang dengan subjek penyandang diabetes tipe 2 sebanyak 42 orang dan subjek normal sebanyak 49 orang. Kriteria inklusi adalah pria atau wanita normal atau penyandang diabetes usia 50-65 tahun, sudah menopause untuk wanita minimal 1 tahun, dan bersedia mengikuti penelitian dengan menandatangani informed concent. Hasil penelitian menunjukkan bahwa Cr serum darah pada penyandang diabetes lebih rendah dibandingkan pada subjek normal. Terdapat hubungan yang signifikan antara HbA1c dengan IMT, lingkar pinggang, aktivitas fisik, Cr serum darah, dan tingkat kecukupan serat. Tingkat kecukupan Cr berpengaruh signifikan terhadap HbA1c. Tingkat Cr serum HbA1C (r = -0.466, p<0.01). kesimpulan dari penelitian ini adalah rendahnya tingkat Cr serum darah diduga menjadi salah satu penyebab berkembangnya diabetes mellitus tipe 2.
KADAR ASAM URAT SUKU SERAWAI DAN SUKU JAWA DI KABUPATEN KEPAHIANG Kiki Puspasari; Ali Khomsan; Faisal Anwar
Media Kesehatan Masyarakat Indonesia Vol. 13 No. 2: JUNI 2017
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.885 KB) | DOI: 10.30597/mkmi.v13i2.1987

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Peran asam urat dalam meningkatkan penyakit ginjal dan kardiovaskuler dalam beberapa tahun terakhir ini sering menjadi perdebatan para ahli. Penyakit kardiovaskuler dan infark miokard dilaporkan dipengaruhioleh tingginya asam urat dalam darah dalam beberapa penelitian besar. Jenis penelitian menggunakan rancangan cross sectional study. Tujuan penelitian ini melihat perbedaan kadar asam urat antara suku Jawa dengan suku Serawai. Penarikan sampel menggunakan purposive sampling dengan 104 orang berusia 40-65 tahun. Data primer berupa data subjek termasuk umur, jenis kelamin, pendapatan, pendidikan, pekerjaan, kadar asam urat. Untuk menganalisis perbedaan dan kadar asam urat darah pada kedua suku dengan menggunakan uji t tidak berpasangan. Suku Serawai 55,8% mempunyai kadar asam urat tinggi dan Suku Jawa yang mempunyai kadar asam urat tinggi sebanyak 40,4%. Dari analisis uji beda kadar asam urat antara Suku Serawai dengan Suku Jawa diperoleh p=0,031 (p<0,005), terdapat perbedaan kadar asam urat antara Suku Jawa dengan Suku Serawai.
SUPLEMENTASI KAPSUL TEPUNG DAUN KELOR (Moringa oleifera Lam) TERHADAP SINDROM PRAMENSTRUASI PADA REMAJA Izna Nurdianty Muhdar; M. Rizal M. Damanik; Faisal Anwar
Media Kesehatan Masyarakat Indonesia Vol. 13 No. 3: SEPTEMBER 2017
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30597/mkmi.v13i3.2674

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Remaja merupakan kelompok wanita usia subur yang rentan menderita premenstrual syndrome (PMS). Daun kelor (Moringa oleifera Lam) mengandung komponen fitokimia dan bermanfaat sebagai antioksidan, antiinflamasi serta analgesik yang berpotensi menghambat prostaglandin dan aktivitas reseptor pusat nyeri. Penelitian ini bertujuan menganalisis pengaruh pemberian kapsul tepung daun kelor terhadap PMS pada remaja. Penelitian yang digunakan adalah eksperimental dengan rancangan randomized pre-post control study. Sebanyak 446 subyek remaja diskrining kemudian dipilih sampel yang memenuhi kriteria inklusi sebanyak 28 subyek yang kemudian dibagi secara random menjadi dua kelompok, yakni kelompok kontrol dan kelompok perlakuan. Analisis data dilakukan dengan menggunakan uji ANOVA dan independent t-test. Penelitian ini menunjukkan bahwa tidak terdapat perbedaan signifikan terhadap karakteristik subyek kontrol dan perlakuan sebelum diberikan intervensi kecuali pada karakteristik usia (p=0,038). Tidak terdapat perbedaan yang signifikan terhadap rerata penurunan skor PMS (p>0,05) sebelum dan setelah intervensi pada kelompok kontrol. Namun, terdapat perbedaan yang signifikan terhadap rerata skor penurunan keluhan PMS pada kelompok perlakuan (p<0,05). Hasil independent t-test menunjukkan terdapat perbedaan yang signifikan (p<0,05) terhadap rerata penurunan skor keluhan PMS antara kelompok kontrol dan kelompok perlakuan. Hasil penelitian ini menyimpulkan bahwa kapsul tepung daun kelor dapat dijadikan sebagai salah satu alternatif untuk menurunkan keluhan PMS.
Status Gizi, Status Kesehatan dan Gaya Hidup pada Wanita Lakto Vegetarian dan Non Vegetarian Widya Astuti; Hadi Riyadi; Faisal Anwar; Ni Ketut Sutiari
Media Kesehatan Masyarakat Indonesia Vol. 15 No. 2: JUNI 2019
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.386 KB) | DOI: 10.30597/mkmi.v15i2.6223

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Vegetarian diet is one of the lifestyle changes. The aims of this study was to analyse the differences of nutritionalstatus, health status, and lifesytle and to analyse correlation between nutritonal status, health status, withlifestyle in lakto vegetarian groups and non lakto vegetarian groups. The design of this study was cross-sectionalstudy include 80 women aged 40-65 years old and was conducted in Bali Province. Data were analyzed using ManWhitney U Test and difference test and Rank Spearman relationship test. This research was funded by Neys-vanHoogstraten Foundation, the Netherlands. The measurement of characteristic of subjek and lifestyle used questioner.The measuerment of body weight used digital scales. Body height was measurement used staturemater,blood pressure was measurement used sphygmomanometer and Hb levels used cyanmethemoglobin. Nonvegetariangroup had higher proportion of obesity and hypertension (50%; 37,5%) than lacto vegetarian groups. Lactovegetarian groups had higher anemia status than non vegetarian groups. The result show there were significantdifferences between nutritional status and consumption coffee into two groups (p<0,05). There were show nocorrelation between nutritonal status, health status, with lifestyle (p>0.05). This study indicates lacto vegetariangroup had better nutritional status, health status, and lifestyle than non-vegetarian group. Lacto-vegetarian grouphad higher risk of anemia.
Keragaman Konsumsi Pangan dan Kejadian Anemia pada Ibu Hamil di Kabupaten Sumenep Madura Dyan Fajar Christianti; Faisal Anwar; Cesilia Meti Dwiriani
Media Kesehatan Masyarakat Indonesia Vol. 15 No. 2: JUNI 2019
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.652 KB) | DOI: 10.30597/mkmi.v15i2.6321

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Pregnant women in Indonesia whose anemic reach 48,9%. The purpose of this study was to analyze thecorrelation between dietary diversity and anemia in pregnant women in Sumenep District, Madura. This study wasa cross-sectional design. The population of this study was 411 pregnant women in four selected health centers inSumenep District. Subjects were all stage of pregnancy (trimester I, II, III) which numbered 200 pregnant womenwho were selected by proportional random sampling. Data were collected through interviews using a questionnaireand direct measurement. The data used consisted of socio-economic status, history of pregnancy, MUAC, hemoglobinconcentration, and Minimum Dietary Diversity-Women (MDD-W) score. Data analysis used the spearmantest to determine the correlation between MDD-W score and hemoglobin concentration in pregnant women.The result showed that 51,5% of pregnant women were anemic. The MDD-W score for anemia and non-anemiagroups was low (4,8±1,2 vs 4,8±1,6). Spearman test showed that the MDD-W score was not associated with hemoglobinconcentration (p>0,05). Factors of significantly associated with haemoglobin concentration were includinggestational age (r=-0,148; p=0,036), BMI pre-pregnancy (r=0,145; p=0,041), and mid-upper arm circumference(r=0,231; p=0,001). Factors related to anemia in pregnant women were the gestational age, nutritional status inpre-pregnancy, and MUAC, while dietary diversity was not related to the incidence of anemia in pregnant women
Faktor Risiko Anemia pada Wanita Pemetik Teh Eryasih Setyorini; Faisal Anwar; Hadi Riyadi; Ali Khomsan
Media Kesehatan Masyarakat Indonesia Vol. 15 No. 3: SEPTEMBER 2019
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.946 KB) | DOI: 10.30597/mkmi.v15i3.7008

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Anemia is known as a public health problem for many years, based on the results of Riskesdas 2018 it isknown that the prevalence of anemia is 48.9%. This research aims to analyze the risk factors that influence anemiain female tea pickers in Pangalengan, Bandung, West Java. The research method was cross-sectional with 148subjects of the so-called Wanita Usia Subur (WUS). They are women of childbearing age, between 18-45 yearsold who were married and not pregnant. They were selected purposively in the plantation areas Purbasari, TalunSantosa and Sedep. This research was part of a research funded by Neys-van Hoogstraten Foundation (NHF).The data obtained are the characteristics of the subjects (age, family size, length and level of education), monthlyfamily expenses for food and non-food, status of nutrition and body composition, and anemia status. The resultsshowed that most of the female tea pickers are 40-44 years old, having family size up to 4 people and 72.3% ofthem are low level educated (89.9% has maximum the elementary school education). The average expenses fornon-food are greater than those for food. Based on various body composition indicators, the female tea pickerswere in general overweight (56.8%), normal upper arm circumference (98.6%). The average total of body fat isgreater than 32,1%, normal visceral fat (≤9%), waist circumference at risk ≥80 cm, and RPP ≥0.8 cm at 81.1%.The prevalence of anemia in tea picking women was 42.6%. Overweight is the most risk factor for anemia becausefat accumulation can reduce iron absorption so that the amount of hemoglobin goes down and erythrocytesdecreases. The age as a protective factor. Anemia can be prevented through nutrition education, healthy lifestyles,and controlling the causes and predisposing factors.
SMOKING HABIT, PHYSICAL ACTIVITY AND HYPERTENSION AMONG MIDDLE AGED MEN[Kebiasaan Merokok, Aktifitas Fisik, dan Hipertensi pada Laki-laki Dewasa] Rian Diana; Ali Khomsan; Naufal Muharam Nurdin; Faisal Anwar; Hadi Riyadi
Media Gizi Indonesia Vol. 13 No. 1 (2018): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (541.37 KB) | DOI: 10.20473/mgi.v13i1.57-61

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Hypertension is a global public health problem. Hypertension prevalence increasing with age, particularly in middle aged men. It is important to identify the modifiable risk factors. The aim of this study was to analyse the correlation of smoking habit, physical activity, and hypertension among middle aged men. This study was conducted in Cianjur District, West Java. 112 men aged 45-59 years old were participated in this cross sectional study. Automatic blood pressure (OMRON Model HEM-7200) was used to measure blood pressure. 24-hour physical activity recall was used to assess physical activity (PA). The correlation between smoking habit and hypertension was analyzed by Chi Square.  The correlation between physical activity and hypertension was analyzed by Spearman.  This study found that 83.9% subjects had smoking habit.  More than half of the subjects (57.2%) had heavy PA. Almost half of the subjects (43.7%) were hypertension. Median of systolic 135.0 mmHg and diastolic 85.0 mmHg. There was a significant correlation between smoking habit (p=0.039) and physical activity (p=0.025) with hypertension. Smoking habit and physical activity correlate with hypertension. Having a moderate to vigorous physical activity regularly particularly in smokers among middle aged men are recommend for decreasing the prevalence of hypertension.
)(Study on the Effects Process on Tannin and Phytic Acid Content in Taro (Colocasia esculenta (L) Schott) M Maman Rohama; Adriana Wahyu Rahmani; Faisal Anwar; Hadi Riyadi; Solechan -
Warta Industri Hasil Pertanian Vol 10, No 1-2 (1993)
Publisher : Balai Besar Industri Agro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2097.474 KB) | DOI: 10.32765/warta ihp.v10i1-2.2398

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A research on the effect of process on tannin and phytic acid content of taro corm has been conduced.The study was done on fresh,boiled,steamed and roasted taro corm and also taro flour.The result showed that uncooked taro contained 750.5 mg of tannin and 374 mg of phytic acid per 100 gr.Boiling treatment showed the decrease of tannin of 50.17% and the decrese of phytic acid of 13.57%.The streaming treatment resulted in the decrease of tannin of 49.90%and the decreaseof phytic acid of 16.30%.Roasting treatment showed of tannin of 53.63% and phytic acid 51.11% and flour treatment showed the decrease of 35.31%tannin and 64.37%phytic acid.  
Anti-Inflammatory Potential of Takokak (Solanum Torvum) Ethanol Extract in Rats Exposed to 7,12-Dimethylbenz[A]Anthracene (Dmba) Nur Rahman; Sri Anna Marliyati; Muhammad Rizal Martua Damanik; Faisal Anwar
Journal of Biomedicine and Translational Research Vol 1, No 1 (2015): April 2015
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (140.787 KB) | DOI: 10.14710/jbtr.v1i1.26

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Background: Takokak fruit (Solanum torvum) is a type of eggplant containing solasodin, solamargin, solasonin and other phytochemicals components with anti-inflammatory and anti-cancer properties. The purpose of this study was to examine the effects of takokak ethanol extract on TNF-α, IL6, and SOD levels.Methods: Experimental factorial study design, with the effect of takokak extract concentration factor (0, 400 and 800 mg/kgBW), takokak extract administration time factor including preventive (weeks 1-7) and curative (weeks 6-12) administration, and necropsy factor (necropsy in weeks 12 and 16). The data obtained included rats body weight, TNF-α, IL-6 and SOD levels.Results: The result showed that the interaction between takokak concentration and handling has significant effect on the increase of TNF-α levels (p=0.003) and the decrease of IL-6 levels (p=0.000). Interaction between takokak concentration, handling and necropsy has significant effect on the increase of SOD levels (p=0.010).Conclusion: Takokak ethanol extract has significant effect on the increase of TNF-α, and SOD levels, and the decrease of IL-6 levels.
Co-Authors . Rimbawa Ade Irawan Adi Teruna Efendi Adi Winarto Adriana Wahyu Rahmani Ahmad Sulaeman Ahmat, Dayu Aji Nugraha Ali Khomsan Amalina Ratih Puspa Aprinia Dian Nurhayati Asih Sulistyorini Uly Damora Budi Setiawan Cesilia M Dwiriani Chica Riska Ashari Clara M. Kusharto Clara Meliyanti Kusharto Dadang Sukandar Desak Putu Yulita Kurniati Desiana Firdaus Dewi Pratiwi Ambari Dewi Ratih Agungpriyono Drajat Martianto Dwi Ariyani Dyan Fajar Christianti Eddy S Mudjajanto Eddy S, Eddy Eddy S. Mudjajanto Eddy Setyo Mudjajanto Eddy Setyo Mudjajanto Eny Palupi Eryasih Setyorini Evy Damayanthi Fachruddin, Kadija Raisa Febriana Ira Dewi Guntari Prasetya Hadi R, Hadi Hadi Riyadi Hakimi Hakimi Hambali Hambali Hardinsyah Hendro Wibowo Herni Yuanda Hutomo, Putra I Made Alit Gunawan Ifanna, Ifanna Ikeu Ekayanti Indah Suryawati Iriyani K Iriyani K Iriyani Kamaruddin Izna Nurdianty Muhdar Joko Widodo jufri, Nurnashriana Julia, Putry Junita, Dini Kartika Musbyarini Kiki Puspasari Kusen, Yustiyani Leily Amalia Lilik Kustiyah M Maman Rohama Mahani Mahani Maizar, Safiratul Maya Sri Maryani Meilla Dwi Andrestian, Meilla Dwi Mira Dewi Muhamad Rizal Martua Damanik N.A. Shofiyyatunnisaak Nancy Dewi Yuliana Naufal Muharam Nurdin Ni Ketut Sutiari Nur Rahman Nurdin Nurdin Nurnashriana Jufri Nurul Hasanah Nuzliah Nuzliah Ploeger, Angelika Putri Julia Putri Julia, Putri Ratika Putriastuti Rian Diana Rian Diana Rimbawan , Risatianti Kolopaking Risatianti Kolopaking, Risatianti Sarah Dilla Nurhidayah SAUDAH SAUDAH Siti Madanijah Siti Madanijah Siti Mutia Rahmawati Solechan - Sri Adiningsih Sri Anna Marliyati Sriyanti Sugeng Riyanto Susi Desminarti Susi Nurohmi TATI NURHAYATI Tjahja Muhandri widya astuti Widya Astuti Widya Astuti Yayat Heryatno Yuanda, Merani