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All Journal Jurnal Akuntansi & Auditing Indonesia Majalah Kedokteran Bandung e-Journal Pustaka Kesehatan Jurnal Sains dan Teknologi Althea Medical Journal Indonesian Journal of Urology Jurnal Sumberdaya Alam dan Lingkungan Journal of Agromedicine and Medical Sciences Jurnal Pendidikan Biologi Indonesia MNJ (Malang Neurology Journal) Al-Jabar : Jurnal Pendidikan Matematika Jurnal Penelitian Politik Medical Laboratory Technology Journal BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Solidaritas Jurnal Respirasi (JR) Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal ABDINUS : Jurnal Pengabdian Nusantara Bestuurskunde: Journal of Governmental Studies JKKI : Jurnal Kedokteran dan Kesehatan Indonesia DHeJA Jurnal Ekonomika Manajemen Dan Bisnis Adopsi Teknologi dan Sistem Informasi Jurnal Manajemen Teknologi dan Sistem Informasi Eksekusi: Jurnal Ilmu Hukum dan Administrasi Negara Jurnal Farmasi SYIFA BERBAKTI: Jurnal Pengabdian Kepada Masyarakat Saber: Jurnal Teknik Informatika, Sains dan Ilmu Komunikasi Jurnal Pengabdian Masyarakat dan Riset Pendidikan Ardhi: Jurnal Pengabdian dalam Negri Pelayanan Unggulan: Jurnal Pengabdian Masyarakat Terapan Jurnal Ekonomi, Manajemen, Akuntansi Journal of Indonesian Social Sciences and Humanities
Rosita Dewi
Fakultas Kedokteran Universitas Jember
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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INFUSA KULIT BAWANG MERAH (Allium cepa L.) MEMPERBAIKI KERUSAKAN HATI TIKUS WISTAR YANG DIINDUKSI DIAZINON Aini, Nada Qurrota; Dewi, Rosita; Pralampita, Pulong Wijang; Helianti, Dina
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 6 No 4 (2023): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

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Abstract

Penggunaan diazinon dalam membasmi hama tanaman akan meninggalkan residu pada tanaman sehingga jika dikonsumsi memberikan dampak buruk. Metabolisme diazinon di hati meningkatkan jumlah radikal bebas dan menurunkan aktivitas enzim antioksidan yang akan mengakibatkan kerusakan sel hati. Kulit bawang merah (Allium cepa L.) mengandung kuersetin yang dapat memperbaiki kerusakan jaringan akibat stres oksidatif. Penelitian ini bertujuan mengetahui hubungan antara dosis infusa kulit bawang merah (IKBM) dan tingkat kerusakan hati tikus yang diinduksi diazinon dan menentukan dosis efektif maksimum IKBM. Tikus dibagi menjadi kelompok normal, diazinon, dan IKBM. Diazinon diberikan dengan dosis 40 mg/kgBB selama 7 hari dilanjutkan dengan IKBM dengan dosis 125, 250, 500, 1.000, dan 2.000 mg/kgBB selama 7 hari. Pengamatan mikroskopik dilakukan terhadap 100 sel hati dengan pewarnaan hematoxylin-eosin (HE) berdasarkan skor Manja Roenigk. Tingkat kerusakan hati antara dua kelompok dianalisis menggunakan uji Mann-Whitney, sedangkan korelasi antara dosis IKBM dan tingkat kerusakan hati, dan dosis efektif maksimum IKBM ditentukan dengan uji regresi. Rerata skor histopatologi hati tertinggi didapatkan pada kelompok diazinon dan terendah pada kelompok normal (p<0,05). Uji regresi menunjukkan terdapat hubungan eksponensial antara dosis IKBM dan tingkat kerusakan hati (p<0,05), yaitu semakin tinggi dosis IKBM, semakin rendah skor histopatologi hati dan dosis efektif maksimum IKBM adalah 1.347,28 mg/kgBB. Sebagai kesimpulan, semakin tinggi dosis IKBM, semakin rendah tingkat kerusakan hati tikus yang diinduksi diazinon. Pemberian IKBM melebihi dosis 1.347,28 mg/kgBB akan meningkatkan kerusakan hati. Kata kunci: bawang merah, diazinon, hati, histopatologi DOI : 10.35990/mk.v6n4.p329-339
Dynamics Of Transmigration Policy As Supporting Policy Of Palm Oil Plantation Development In Indonesia Widyatmoko, Bondan; Dewi, Rosita
Journal of Indonesian Social Sciences and Humanities Vol. 9 No. 1 (2019): Journal of Indonesian Social Sciences and Humanities
Publisher : RMPI-BRIN

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Abstract

Transmigration is the program which cannot be separated with the success story of palm oil development in Indonesia. Transmigrants becomes the engine to build the palm oil smallholder. The involvement of transmigrant in the PIR-Trans program, primary credit for member Scheme (KKPA), and revitalization scheme has been accelerating the palm oil plantation development in Indonesia. However, the “success” of developing palm oil plantation in Indonesia through scheme mentioned above was not without flaws. Unclear of land status or overlapping claim become the biggest problems faced nowadays. This paper aims to observe the development transmigration program and palm oil development in Indonesia. By analyzing policies of both transmigration programs and palm oil development from different political administration, this paper shows that, first, transmigration policy went from narrative of security, economic growth to border development and security. Second, under those different policy narratives, transmigration policy has been accommodated to the development of palm oil in Indonesia. Transfer of central authority to local government in executing transmigration movement and settlement has been addition to local government operational permission authority for palm oil development.
Potential of shallot peels as a daily antioxidant supplement against cigarette smoke-induced lung damage Helianti, Dina; Dewi, Rosita; Munawaroh, Ayu; Rachmania, Sheilla; Maulana, Aditha Satria; Abrori, Cholis; Sumadi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 3, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss3.art10

Abstract

Background: Cigarette smoking damages the alveoli through oxidative stress. Shallot peels containing flavonoids, especially quercetin, potentially serve as a daily antioxidant supplement to impede lung tissue damage induced by cigarette smoke. However, the maximum effective dose is yet to be determined. Objective: This research was designed to establish the maximum effective dose of shallot peel infusion (SPI) to prevent oxidative stress and histopathological lung damage induced by cigarette smoke. Methods: This experimental laboratory was a posttest-only control group design. A total of 24 male Rattus norvegicus Wistar strain, were allocated into 6 groups: a control group and 5 SPI-treated groups. All rats were exposed to 2 cigarettes/day and were treated for 28 days with aquabidest and different doses of SPI (0 mg/kgBW, 125 mg/kgBW, 250 mg/kgBW, 500 mg/kgBW, 1,000 mg/kgBW, and 2,000 mg/kgBW). The level of oxidative stress in serum was measured malondialdehyde (MDA) level with ELISA, and histopathological lung damage was estimated using the lung histopathological damage scoring method assessing inflammatory cells, alveolus lumen and inter-alveoli junction.Results: The quadratic regression analysis revealed the maximum effective dose of SPI to prevent oxidative stress and lung damage were 1,435 mg/kgBW and 1,206 mg/kgBW, respectively. In the histopathological examination of the lungs, the administration of SPI up to a dose of 1206 mg/kg BW prevents the inflammatory process caused by cigarette smoke, which is indicated by the number of inflammatory cells, the thickness of the alveolar septum, and the increasingly normal shape of the alveolar lumen.Conclusion: SPI doses of less than 1,206 mg/kgBW are safe and effective daily antioxidant supplements in rats exposed to cigarette smoke and have the potential to be further studied for application in humans.
Liver Histopathological Analysis in The Acute Toxicity Test of Shallot (Allium cepa L.) Peel Extract in Rats (Rattus norvegicus) Aprilya Pratiwi, Nadilla; Dewi, Rosita; Agustina, Dini; Helianti, Dina; Rachmania, Sheilla
Journal of Agromedicine and Medical Sciences Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i3.53736

Abstract

Shallot (Allium cepa L.) contains bioactive compounds with antioxidant effects. In addition to the tuber, the shallot’s peel is a rich source of flavonoids with demonstrated capacity to mitigate oxidative stress. Prior studies have evaluated the antioxidant efficacy of shallot peel in ameliorating organ damage and have established its maximum effective dose. The subsequent step required for its potential therapeutic application is toxicity test. This study aimed to analyze the liver histopathological changes in the acute toxicity test of shallot peel extract (SPE) in rats based on OECD TG 420. This research was an experimental with a post-test-only control group design. Five female rats were used as the control group administered dimethyl sulfoxide (DMSO), while 5 female rats were used in the treatment group administered SPE at 5,000 mg/kg body weight (BW) (one of them had been used for a preliminary test with the same dosage). On day 15, a necropsy was conducted, followed by histopathological observation of the hematoxylin-eosin (HE)-stained liver histopathological slide. The damage to hepatocytes was evaluated using Manja Roenigk criteria. The average histopathological score per liver cell of the control group was 1.226 ± 0.0065 and the treatment group was 1.235±0.0079. The Mann-Whitney test showed that the liver histopathological score of the treatment group was not different from that of the control group (p>0.05). It can be concluded that SPE 5,000 mg/kg does not show acute toxic effects in rats, with LD₅₀ estimated at >5,000 mg/kg according to OECD standards.
Praktik Pendampingan Hukum Permohonan pada Posbakum yang Bekerjasama dengan Lembaga Bantuan Hukum Legundi Dewi Rosita; Nadaa Avria Hanum
Pelayanan Unggulan : Jurnal Pengabdian Masyarakat Terapan Vol. 2 No. 4 (2025): November: Pelayanan Unggulan : Jurnal Pengabdian Masyarakat Terapan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/unggulan.v2i4.2374

Abstract

Legal assistance for applications is a crucial form of legal aid provided to the public in submitting various types of applications to the courts or related agencies. This research is motivated by the urgent need to understand the effectiveness and implementation of such legal aid services, particularly for underprivileged communities who face barriers in accessing the justice system. This article aims to discuss and describe in detail the application processing process carried out by the Legal Aid Post (Posbakum) when operating and collaborating with the Legundi Legal Aid Institute (LBH Legundi), specifically in the context of name change applications. This research uses normative legal methods with a conceptual and statutory approach to analyze the applicable procedures. The results show that Posbakum plays a central role in drafting name applications for communities in need through a phased assistance process that includes initial consultation, verification of document requirements, technical assistance in scanning and nazegel, drafting application letters, and guidance on case registration. This assistance model has proven effective in overcoming procedural obstacles and increasing access to justice for underprivileged communities, while simultaneously transforming the community from a passive to an active role in fighting for their civil rights.
Analisis Kualitas Layanan SIAKAD Universitas Dinamika Bangsa Jambi Menggunakan Metode Webqual 4.0: Analisis Kualitas Layanan SIAKAD Universitas Dinamika Bangsa Jambi Menggunakan Metode Webqual 4.0 Dewi, Rosita; Dodo Zaenal Abidin; Effiyaldi
Jurnal Manajemen Teknologi Dan Sistem Informasi (JMS) Vol 5 No 2 (2025): JMS Vol 5 No 2 September 2025
Publisher : LPPM STIKOM Dinamika Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33998/jms.2025.5.2.2346

Abstract

This study aims to analyze the service quality of the SIAKAD website at Universitas Dinamika Bangsa Jambi using the WebQual 4.0 method. The issues raised include the impact of access speed, the SIAKAD system on user expectations, the completeness and accuracy of data, and an overall analysis of the SIAKAD service quality. The study uses three main variables: Information Quality, Interaction Quality, and Usability Quality, with 311 respondents categorized by gender, age, and academic program cohort. The results show that Information Quality and Interaction Quality have a significant impact on user satisfaction, while Usability Quality does not have a significant effect. An R-Square value of 85% indicates that the service quality of SIAKAD at Universitas Dinamika Bangsa Jambi is good and positively influences user satisfaction. This study concludes that users are satisfied with the quality of the SIAKAD website services, except in terms of Usability.
Penataan Ulang Area Produksi Industri Rumah Tangga Kabupaten Bekasi Sari, Dessy Agustina; Hakiim, Azafilmi; Irawan, Riyant; Dewi, Rosita
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 4 No 1 (2020): Volume 4 Nomor 1 Tahun 2020
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v4i1.14602

Abstract

Betawi’s taffy made of sticky rice was one of the best economic commodities for sub-district Cibitung’s citizens. Furthermore, this product usually gave success in a yearly exhibition for district Bekasi. For a long time, demand a trust the costumers were longer completed through the serving of nutrient food and the hygiene concept. That became a challenge for the owner and the Sukajaya village’s leader to decrease the resellers. Afterward, the breakthrough way guided selling the product into the food and the gift store in the scale of the home industry, which attached the label below monitoring the Service of Healthy (P-IRT). Achieve that, the initial step has been done that supported the guiding in the Sukajaya village and LPPM Unsika. The next activity for the site work evaluation also has been executed. It is such as providing a base for raw material until product and cover for the roof in around production line, giving the name for each section place, and pin the license certificate. Neat and clean aspects gave an esthetic point. Furthermore, it positively affected the occupation program of Sukaya village in the district Bekasi level.
Analisis Pengaruh Ukuran Komite Audit Dan Keberagaman Gender Komite Terhadap Kualitas Pelaporan Keuangan Di Sektor Transportasi Dan Logistik Dewi, Rosita; Ansari, Rahman; Pribadi , Muhammad Iqbal
Jurnal Ekonomi Manajemen dan Bisnis (JEMB) Vol. 4 No. 2 (2025): Juli-Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jemb.v4i2.3251

Abstract

In 2018, PT Garuda Indonesia was involved in a financial statement manipulation scandal that affected investor confidence in the Indonesian capital market. The actions were indicated as window dressing. Based on POJK No. 39/POJK03/2019/Regarding SAF Commercial Banks, window dressing refers to the manipulation of financial statements with the aim of presenting the company's financial condition in a more favorable light than the actual reality. This study uses a quantitative approach with secondary data collected through documentation techniques. The sample was determined using purposive sampling, comprising 158 data samples. Analysis was conducted using classical assumption tests, multiple linear regression tests, hypothesis tests, and coefficient of determination tests. The results of the study indicate that the size of the audit committee has a significant effect on financial reporting quality, while gender diversity in the committee does not have a significant effect on financial reporting quality.
ACUTE TOXICITY TEST OF RED ONION (Allium Cepa L) SKIN EXTRACT ON KIDNEY HISTOPATHOLOGY OF RATS (Rattus Norvegicus) Brahmantya Putra, Denny Christian; Helianti, Dina; Wahyudi, Septa Surya; Dewi, Rosita
Indonesian Journal of Urology Vol 33 No 2 (2026)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v33i2.1000

Abstract

Introduction: Shallots (Allium cepa L.) are known to contain quercetin, which is helpful as an antioxidant, but its accumulation in the body can be toxic. Objective: This study aims to determine the effect of administering red onion skin extract on histopathology and weight of the kidney, body weight, and clinical symptoms, as well as determining the LD50. Material & Methods: This research was conducted according to OECD guideline No. 420 Fixed Dose Procedures. Rats were allocated to a control group that was given 3% DMSO and a treatment group that was given red onion peel extract at a dose of 5000 mg/kgBW. Kidney histopathology slides with Hematoxylin-eosin staining were observed by two observers in five fields of view using Fiji ImageJ software and assessed based on the Kocoglu scoring. Kidney histopathology data was analyzed using the Mann-Whitney test, while kidney weight and body weight gain used the Independent Sample T-test. Results: The treatment group experienced significantly higher body weight gain than the control group. On the other hand, observations of the histopathological appearance and weight of the kidney did not show any significant differences. Observation of clinical symptoms showed normal results with no deaths. Conclusion: Administration of 5000 mg/kgBW red onion skin extract in the acute toxicity test had no effect on the histopathology and weight of kidney rats, but had a significant effect on body weight gain. The LD50 of red onion skin extract was found to be >5000 mg/kgBW. Keywords: Red onion skin extract, acute toxicity test, LD50, kidney histopathology.
Co-Authors Adi Darma Effendi Afrina, Cut Agus R Rahman Agustina, Ani Aini, Nada Qurrota Ajeng Margareta Sari Al Munawir Alif Mardijana Amilin Amilin Angga Mardro Raharjo, Angga Mardro Ansari, Rahman Apriani, Susi Aprilia, Annisa Nadya Aprilya Pratiwi, Nadilla Awani Irewati Azham Purwandhono Aziz, Ayu Munawaroh Bintang, Muhammad Farrel Ravidinata Masoga Bi’izzyk, Avie Baldana Brahmantya Putra, Denny Christian Cholis Abrori, Cholis Chrisnaji Banindra Yudha Cicih Komariah CPF. Luhulima Damayanti Suhita Dessy Agustina Sari Dewantoro, Dicky Dewi Riniarti Dhiah Anis Salsabila Dina Helianti Dini Agustina Dita Diana Parti Dodo Zaenal Abidin Effiyaldi Eko Subastian Elly Nurus Sakinah, Elly Nurus Erfan Efendi Erma Sulistyaningsih Gianevan, Nicholas Jirezra Gilang Vigorous Akbar Eka Candy Hafidin, Muhammad Ananda Faris Hakiim, Azafilmi Hasyim Asy’ari Hayati Nufus Herdhata Agusta Herniyanti Indriana Kartini Irawan Fajar Kusuma Irawan, Riyant Julius Kalangi Kamila, Vina Zahrotun Khoirul Fahri Arrijal Laily Rahmawati liza Marlia Luthfiyyah, Nur Atikah M. Ali Shodikin Mahriani Mahriani Maria Ulfa Maulana, Aditha Satria Moch. Agus Krisno Budianto Muhammad Noor Kholid Muhammad Zidan Muhtar Ady Kusuma Munawaroh, Ayu Nadaa Avria Hanum Nindya Shinta Rumastika Nurhaliza, Salsabilla Pelita Sari Pralampita, Pulong Wijang Prasetya, Eky Pribadi , Muhammad Iqbal Putut Pamilih Widagdo, Putut Pamilih Rahami, Nahla Ahmad Rahma, Nafisah Hani Asyifah Rena Normasari Rini Riyanti Roat Yeti Mustafida Rosita Sopwi Nur Lailly Sandy Nur Ikfal Raharjo Sa’diyah, Nindya Audatus septa surya wahyudi, septa surya Setyadi, Hario Jati Shabrina Shahifa Audy Rahima Sheila Rachmania Sheilla Rachmania, Sheilla Sillehu, Sahrir Siti Zaenab Solihin Sidik Sudradjat Sudradjat Sulistyaningsih , Erma Sumadi Susantin Fajariyah Teuku Salfiyadi Tri Nuke Pudjiastuti Widyatmoko, Bondan WINARTI WINARTI Winarti Winarti Yan Sukmawan, Yan Yuli Hermansyah Yuli Hermansyah, Yuli Yunita Armiyanti Zahniar, Zahniar