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All Journal Jurnal Natur Indonesia Jurnal Perikanan dan Kelautan Jurnal Sains Dasar Jurnal Ilmu Perairan (Aquatic Science) JURNAL PETERNAKAN Jurnal Riset Kimia Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Biology, Medicine, & Natural Product Chemistry Medical Laboratory Technology Journal ALCHEMY Jurnal Penelitian Kimia Jurnal Penelitian Farmasi Indonesia JOPS (Journal Of Pharmacy and Science) JURNAL PHOTON JFL : Jurnal Farmasi Lampung Jurnal Ilmu Kefarmasian Indonesia Jurnal Dunia Farmasi Asian Journal of Aquatic Sciences Acta Chimica Asiana Jurnal Insan Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Journal of Artificial Intelligence and Digital Business Jurnal Katalisator Jurnal Farmasi Indonesia Jurnal Pengabdian Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Perikanan dan Kelautan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Musyirna Rahmah Nst
Sekolah Tinggi Ilmu Farmasi Riau
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Optimizing carrot extract serum (Daucus carota L.) for anti-aging: efficacy in moisturizing and pore size reduction using Box-Behnken design method Iskandar, Benni; Antasya, Vaylia; Nasution, Musyirna Rahmah; Frimayanti, Neni; Peng-Wei, Ching; Khairani, Sondang
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1566

Abstract

Carrot extract (Daucus carota L.) contains various bioactive compounds, including vitamins A, B, and C, alkaloids, flavonoids, tannins, anthraquinones, saponins, diterpenes, steroids, beta-carotene, phenols, terpenoids, and minerals, all of which possess antioxidant properties. These compounds are known to help slow down the aging process. The aim of this study was to determine the optimal concentrations of gelling and alkalizing agents, assess their interactions, and evaluate the anti-aging effects of the most effective serum formulation. The formulation was optimized using the Box–Behnken design with two key factors: Carbopol 940 concentration (0.5–1%) and triethanolamine (0.5–1%). The effects on pH, adhesion, and spreadability were evaluated. The best formulation was achieved with 0.837% Carbopol 940 and 0.855% triethanolamine, showing a pH error of 2.45%, adhesion error of 0.76%, and spreadability error of 1.01%, all within acceptable limits (errors < 10%). After four weeks of stability testing, the formulation remained stable, well-mixed, with a pH of 5.16, an adhesion time of 1.60 seconds, and spreadability of 6.73 cm, with no discomfort. The combination of Carbopol 940 and triethanolamine improved the physical properties, enhancing anti-aging effects compared to the base formula. The optimized serum increased skin moisture by 84.62%, reduced pore size by 64.71%, lightened spots by 62.79%, and reduced wrinkles by 67.50%. This indicates the optimized carrot extract serum is stable, safe, and effective as an anti-aging agent, making it a promising natural skincare product.
THE ROLE OF THE COMMUNITY IN ENVIRONMENTAL MANAGEMENT IN THE COASTAL AREA OF RUPAT DISTRICT Bathara, Lamun; Nedi, Syahril; Effendi, Irwan; NST, Musyirna Rahmah; Nasution, Tio Afandi; Tanjung, Afrizal
Asian Journal of Aquatic Sciences Vol. 8 No. 3 (2025): December
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/ajoas.8.3.364-372

Abstract

Coastal environmental problems in Rupat District cannot be resolved solely through a top-down approach or government intervention. This study was conducted in 2025 with the intention of comprehensively analyzing the role of the community in environmental management in the coastal areas of Rupat District, particularly on Ketapang and Lancah beaches. Through a systematic research approach, this study aims to identify the forms of community roles in coastal environmental management efforts, analyze factors that influence the level of community participation, describe the various challenges faced in implementing community-based environmental management, and formulate strategies for strengthening community roles that can be implemented sustainably. The method used in this study was a survey method with a total of 31 respondents, consisting of fishermen, seaweed farmers, fish traders, community leaders, and people involved in marine tourism activities. The results of the study can be concluded that community-based coastal environmental management has enormous potential but faces complex structural challenges
Optimizing carrot extract serum (Daucus carota L.) for anti-aging: efficacy in moisturizing and pore size reduction using Box-Behnken design method Iskandar, Benni; Antasya, Vaylia; Nasution, Musyirna Rahmah; Peng, Wei-Ching
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1566

Abstract

Carrot extract (Daucus carota L.) contains various bioactive compounds, including vitamins A, B, and C, alkaloids, flavonoids, tannins, anthraquinones, saponins, diterpenes, steroids, beta-carotene, phenols, terpenoids, and minerals, all of which possess antioxidant properties. These compounds are known to help slow down the aging process. The aim of this study was to determine the optimal concentrations of gelling and alkalizing agents, assess their interactions, and evaluate the anti-aging effects of the most effective serum formulation. The formulation was optimized using the Box–Behnken design with two key factors: Carbopol 940 concentration (0.5–1%) and triethanolamine (0.5–1%). The effects on pH, adhesion, and spreadability were evaluated. The best formulation was achieved with 0.837% Carbopol 940 and 0.855% triethanolamine,  showing a pH error of 2.45%, adhesion error of 0.76%, and spreadability error of 1.01%, all within acceptable limits (errors < 10%). After four weeks of stability testing, the formulation remained stable, well-mixed, with a pH of 5.16, an adhesion time of 1.60 seconds, and spreadability of 6.73 cm, with no discomfort. The combination of Carbopol 940 and triethanolamine improved the physical properties, enhancing anti-aging effects compared to the base formula. The optimized serum increased skin moisture by 84.62%, reduced pore size by 64.71%, lightened spots by 62.79%, and reduced wrinkles by 67.50%. This indicates the optimized carrot extract serum is stable, safe, and effective as an anti-aging agent, making it a promising natural skincare product.
Kombucha tea from ambarella fruit as a natural antibacterial agent against Escherichia Coli and Staphylococcus aureus Musyirna Rahmah Nasution; Agfa Febriyananda
Acta Chimica Asiana Vol. 8 No. 2 (2025)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v8i2.257

Abstract

Kombucha tea is a traditional fermented beverage known for its probiotic benefits, produced from sweetened tea fermented with a Symbiotic Culture of Bacteria and Yeast (SCOBY). Recent innovations have focused on enhancing its functional properties using local fruit extracts. However, studies on the incorporation of Spondias dulcis (kedondong), a native fruit of Riau, remain limited. This study aims to formulate kombucha tea enriched with kedondong juice and evaluate its quality and antibacterial activity against Escherichia coli and Staphylococcus aureus. Four formulations were prepared with kedondong juice concentrations of 0% (F1), 10% (F2), 20% (F3), and 30% (F4). Parameters observed included organoleptic properties, pH, alcohol content, microbial growth, and total acidity. Antibacterial activity was tested using the disc diffusion method, and results were statistically analyzed using One-Way ANOVA. F4 on day 7 showed the highest inhibition zones (13.30 mm for E. coli and 14.49 mm for S. aureus), with significant differences between formulations (p < 0.05). This study highlights the potential of kedondong-enriched kombucha tea as a functional probiotic beverage and a natural source of mild antibacterial agents, offering an innovative approach to utilizing local biodiversity in public health.
Co-Authors -, Hasmalina Abdi Wira Septama Abdifi, Reza Afnita, Fakhiratunnisa Afrida Yeti Afrizal Tanjung Agfa Febriyananda Agustini, Tiara Tri Akmal Djamaan Amnan, Wekis Raya Anggraini, Annisa Fitri Anita Lukman Annisa Riski Permata Sari Antasya, Vaylia Aqilla, Alya Armon Fernando Armon Fernando Arundita, Silvy Aulya, Nurliza Ayuni, Putri Azhari, Weriska Restu Bella Ardhiyati BENNI ISKANDAR Cahyani, Ardhia Regita Dasni Syafril Dasni Syafril Deni Anggraini Diwa, Resi Oktamara Dwi Andreyas Elsa Etavianti Emrizal Enda Mora Etavianti, Elsa Febrian, Dyan Fina Aryani, Fina Firman Nugroho Fitri, Ramadini Fitri, Valentina Furi, Mustika Ginta Rio Maranti Gressy Novita Gustina &#039; Haiyul Fadhli Hanifa, Elvi Hasmalina - Hasmalina Nasution Husnawati Ihsan Ikhtiarudin Intan Putri Utami Irwan Irwan Jannah, Ninuk Rodhiatul Ladiona, Maria Yella Lamun Bathara Manik, Dhea Putri Bertuah Br Maria Yella Ladiona Martina Br Manullang Masnun, Lidiatil Meiriza Djohari, Meiriza Melati, Putri Melzi Octaviani Milianty, Jesy Muthmainnah, Nurillah Nabilah, Clara Nabilla, Vivi Gita Nanang Nasution, Tio Afandi Neni Frimayanti Ningrum, Tilar Eka Widia Ningsih, Yozi Fiedya Nur Rahmadani Fitri Nurhapipah, Nurhapipah Pardede, Depa Gloria Kristin Peng, Wei-Ching Peng-Wei, Ching Putri Lestari, Putri Putri Putri, Putri Rabiatul Adawiyah Rahayu Utami Rahayu Utami Utami Rahma Dona Rahman, Sumiati Rajeb Fadillah ramadhan, alfitrah Ramadhani, Elsha Fadhika Dwi Ratna Sari Dewi Reza Abdifi Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti Ronapadua Sahara Ruska, Shinta Liana S.Farm., M.Farm., Apt, Sondang Khairani Safitri, Ramanda Sahara, Ronapadua Sakinah, Norma Septi Muharni Silvera Devi Simanjuntak, Asnika Putri Sri Hardianti Sudarsi, Yulisma Suhelmi - Suhelmi - Sumiati Rahman Syahbandi, Ilham Syahril Nedi Syamira Tri Budhi Murdiati Tri Budhi Murdiati Tria Halianti Triani, Leni Winda Sri Wahyuni Wira Noviana, Wira Noviana Wulan Desmar Utari Yuharmen - Yulisma Sudarsi Yunelva, Rinda