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The Role of Body Mass Index, Hemogblobin Levels in Women Giving Birth to Neonatal Weight Linda Yanuana Fanida Tantowi; Dita Pratiwi Kusuma Wardani; Kurniawan; Dewi Ambarwati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 17 No 1 (2023): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v17i1.5774

Abstract

Maternal nutritional status is monitored with BMI and is also one of the factors that have an impact during pregnancy. Poor nutrition before and during pregnancy leads to decreasing hemoglobin levels and low birth weight infants. This study aims to determine the correlation between hemoglobin levels and BMI of mothers giving birth to the weight of newborns at the Puskesmas Kebumen II, Kebumen District. This research used a retrospective study with medical record data collected from January to April 2022. This research involved 50 patient mothers giving birth at Puskesmas Kebumen II, Kebumen District. The data were analyzed by the Pearson correlation coefficient test. The results are BMI and newborn weight (p = 0.061, r = 0.367), hemoglobin levels, and newborn weight (p=0.852; r= -0.025). There was no correlation between BMI and hemoglobin levels to newborn weight at Puskemas Kebumen II, Kebumen District.
Toxoplasma gondii-Driven Cytokine Dysregulation as a Differentiating Biomarker Between Schizophrenia and Depression Lathifatul Azka Nurul Aini; Dita Pratiwi Kusuma Wardani; Isna Hikmawati; Ikhsan Mujahid
Journal of Education Technology Information Social Sciences and Health Vol. 5 No. 2 (2026): September 2026
Publisher : CV. Rayyan Dwi Bharata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57235/jetish.v5i2.9011

Abstract

Schizophrenia and depression are among the most prevalent psychiatric disorders, and both have been mechanistically linked to systemic and neuroinflammatory processes. Infection with the protozoan parasite Toxoplasma gondii has been proposed as a potential trigger of these inflammatory pathways, yet direct comparisons of proinflammatory cytokine profiles between the two disorders in the context of T. gondii infection remain scarce. Consequently, it is still unclear whether schizophrenia and depression share a common toxoplasmosis-associated inflammatory signature or instead display distinct immunological fingerprints. This systematic review aimed to characterize the proinflammatory cytokine biomarker patterns—particularly IL-6, IFN-γ, and TNF-α—among T. gondii-infected patients with schizophrenia and depression. Conducted in accordance with the PRISMA 2020 guidelines and the PICO framework, the review searched PubMed Central, PubMed, ScienceDirect, and Scopus for original English-language studies published between 2021 and 2025. Of 454 records initially retrieved and screened for eligibility using Mendeley Reference Manager, five studies satisfied all inclusion criteria. The synthesis revealed that toxoplasmosis-associated schizophrenia was characterized by elevated MCP-1, RANTES, GRO-α, IP-10, and IL-8, along with reduced MIP-1α, MIP-1β, and IL-8, whereas toxoplasmosis-associated depression was primarily characterized by increased IL-6 and TNF-α. These divergent cytokine patterns suggest that chronic T. gondii infection induces disorder-specific immune dysregulation rather than a uniform inflammatory response. Such distinct profiles may hold promise as biomarkers for differentiating infection-related psychiatric subtypes and could inform the development of more targeted, immunomodulatory therapeutic strategies for affected patients
Co-Authors Agesti, Eka Fauzia Almanfaluthi, Muhammad Lutfhi ALMANFALUTHI, MUHAMMAD LUTHFI Amalia Ovi Mustika Seno Ambarwati, Dewi Annisa Nur Chaeni ANNISA SHOFIA FAJRO Aprianto . Arif Mulyanto Arif Mulyanto Arif Mulyanto, Arif Atika Nur Azizah ATIKA NUR AZIZAH Azizah, Atika Nur Cahyaningrum, Winda Rahma Chaeni, Annisa Nur Citra Nadia Salsabila Defi Nurul Hayati Dewi Ambarwati Dewi Kristiya Nugra Heny Dhanti, Kurnia Ritma Dhanti, Kurnia Ritma Dina Aristya Purdiani EKANIASARI, MEVIANA DEA Farida Dwi Handayani Faza, Thariqi Mushthafa Firman Jaelani HAMNA FATHIA ZAHRA Handayani Narendo Putri handayani, Farida Hanny Dwi Indah Nurcahyani Heny, Dewi Kristiya Nugra Hikam Mika'il Ika Wulan Nuri Anggreani Ikhsan Mujahid Ikhsan Mujahid IKHSAN MUJAHID Ikhsan Mujahid Indah Mulyani Ismi Andina Pertiwi Isna Hikmawati Isna Hikmawati ISNA HIKMAWATI Janatin Nur Aripin JANG JAYA, NABELA PUTRI Ketut Tirtayasa Kurnia Rhitma Dhanti Kurnia Ritma Dhanti Kurniawan Kurniawan Kurniawan Lathifatul Azka Nurul Aini Linda Wijayanti Linda Yanuana Fanida Tantowi Listiyowati, Tanti M Luthfi Almanfaluthi M. Luthfi Almanfaluthi Minto Rahaju Minto Rahaju Muhammad Lutfhi Almanfaluthi Muhammad Luthfi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi MUJIONO, TIMBUL Nadia Ega Haliza NADIA RIZQI AULIA Nuri Anggreani, Ika Wulan Nurul Badriyah Nurul Badriyah Nurul Qomariyah Oei Stefani Yuanita Widodo OEI STEFANI YUANITA WIDODO Oktafian Diyas Tamtama Olivia Alfitri Qo'imah, Alamanda Nurul Qo’imah, Alamanda Nurul Rahaju, Minto RETNO SULISTIYOWATI Retno Sulistiyowati Retno Sulistyowati Retno Sulistyowati RETNO SULISTYOWATI RINA MAULINA Ristiyanto Ristiyanto Ristiyanto ROHMAH, JAZILATUR Santi Safitri Shely Ayu Lestari SUDARSONO, TANTRI ANALISAWATI Sudarsono, Tantri Analisawati Supriyadi Supriyadi Supriyadi Supriyadi Syafira Dian Ergiana Syifa Arrachmah Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono ULI MAS'ULIYAH INDARWATI Uli Masuliyah Indarwati VIRGINIA ULAFA ANNIDA Widodo, Oei Stefani Yuanita Wijayanti, Linda Yunita Nurmalasari