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All Journal Farmaka Indonesian Journal of Pharmaceutical Science and Technology JURNAL PHARMASCIENCE IDJP (Indonesian Journal of Pharmaceutics) Jurnal Kesehatan Bakti Tunas Husada IKRA-ITH Teknologi Jurnal Sains dan Teknologi Journal of Pharmacopolium Majalah Farmasetika Pharmacoscript Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Riset Kefarmasian Indonesia Indonesia Natural Research Pharmaceutical Journal (INRPJ) Science Midwifery Karya Kesehatan Siwalima Jurnal Pengabdian Masyarakat (Jupemas) Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Jurnal Kesehatan Bakti Tunas Husada Jurnal Sains Farmasi dan Kesehatan Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Analit: Analytical And Environmental Chemistry Journal of Pharmascience
Garnadi Jafar, Garnadi
Fakultas Farmasi, Universitas Bhakti Kencana
Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other

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Formulation and Characterization of Tretinoin Nanostructured Lipid Carriers Using Apifil and Cremophore Jafar, Garnadi; Putriyanti, Al-fira; Muhsinin, Soni
Indonesian Journal of Pharmaceutics Vol 5, Issue 3, Sept - Dec 2023
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v5i3.54349

Abstract

The most widely used vitamin A derivative for mild to severe acne is tretinoin. However, it is lipophilic (LogP 6.3). Tretinoin must be transformed into liquid lipids and NLC (nanostructured lipid carriers) based on Apifil® and stabilized by surfactants to address permeability and stability concerns. Heat homogenization and sonication with a sonicator probe were used to formulate tretinoin into NLC. Apifil®, Myritol®, and Chremophore® RH 40 were the materials utilized. Particle size, polydispersity index, zeta potential, adsorption effectiveness, and morphological measurements were then used to describe NLC. The characterization results showed that NLC tretinoin has a particle size of <200 nm for 2 measurements over 30 days, a polydispersity index value of 0.5, a zeta potential range of -7 mV to -19.3 mV, and an efficiency entrapment value of >80% for all formulas. Spherical shape emerged from the morphology data. Conclusion: The findings demonstrate that tretinoin's nanostructured lipid carriers provide favorable characterization outcomes. Keywords: Diabetes, Metformin HCl, Extended release, Direct compressed,                     Hypromellose, Carboxymethylcellulose natrium.
PEMBENTUKAN NANOSTRUCTURED LIPID CARRIER TRETINOIN MENGGUNAKAN COMPRITOL® ATO DAN CREMOPHOR® RH 40 DENGAN METODE SONIKASI PROBE Jafar Garnadi; Buana Irviana Prita; Fatmawati Fenti
Pharmacoscript Vol. 7 No. 2 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i2.1646

Abstract

Tretinoin merupakan retinoid generasi pertama yang banyak digunakan dalam pengobatan jerawat yang memiliki karakteristik yaitu bersifat lipofilik (LogP 6,3) dan berpotensi sulit diformulasikan dan pengaplikasian dapat mengiritasi kulit. Salah satu alternatif sistem penghantaran tretinoin adalah Nanostructured Lipid Carrier (NLC) yang merupakan sistem penghantaran terdiri dari campuran lipid cair, lipid padat, dan surfaktan. Penelitian ini bertujuan untuk memformulasikan dan karakterisasi NLC tretinoin menggunakan lipid padat Compritol® ATO dan surfaktan Cremophor® RH 40. Metode yang digunakan dalam pembuatan NLC tretinoin dari lima formula dengan variasi konsentrasi lipid padat dan surfaktan, metode yang digunakan homogenisasi panas dan dilanjutkan dengan sonikator probe selanjutnya dilakukan karakterisasi meliputi ukuran partikel, indeks polidispersitas, dan potensial zeta serta penetapan efisiensi penjerapan. Hasil karakterisasi NLC tretinoin selama 30 hari memiliki karakterisasi yang baik yaitu ukuran partikel <600 nm, indeks polidispersitas <0,5, zeta pontensial + -19 mV dan efisiensi penjerapan >80% serta memiliki bentuk morfologi yang sferis.
PENDEKATAN SISTEM PENGHANTARAN NANOPARTIKEL BERBASIS LIPID SEBAGAI OBAT ANTIJERAWAT : REVIEW: Putriyanti Al-fira; Jafar Garnadi; Mulyani Yani
Pharmacoscript Vol. 7 No. 2 (2024): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v7i2.1761

Abstract

Jerawat adalah gangguan kulit yang terjadi ketika folikel rambut tersumbat oleh minyak dan sel kulit mati. Bakteri gram positif propionibacterium acnes adalah akar dari jerawat. Propionibacterium acne tumbuh karena akumulasi sebum, yang menyebabkan jerawat. Untuk mengatasi jerawat, berbagai bahan aktif dan metode pengobatan telah dikembangkan. Penghantaran melalui nanoteknologi adalah metode terbaru yang digunakan. Ini dipilih karena kemampuan nanoteknologi untuk meningkatkan stabilitas bahan aktif, meningkatkan penetrasi bahan aktif ke dalam kulit, dan memungkinkan zat aktif dibawa ke area yang ditargetkan. Metode yang digunakan yaitu Artikel ilmiah dikumpulkan dari sumber nasional dan internasional 10 tahun terakhir (2014-2024). Hasil yang ditunjukkan bahwa metode nanopartikel menunjukkan potensi besar sebagai bahan aktif anti jerawat karena ukurannya yang kecil memungkinkan penetrasi kulit lebih baik, pelepasan bahan aktif secara terkendali, dan perlindungan dari degradasi lingkungan. Keberhasilannya terbukti dalam berbagai studi dan uji klinis, dengan penurunan signifikan jerawat dan peningkatan kondisi kulit. Pengembangan terbaru, seperti nanopartikel lipid, nanopartikel polimer, dan nanopartikel metal. Diskusi dalam review artikel ini melakukan pendalaman terhadap pengembangan obat dan sitem penghantaran obat baru, meliputi proses sintesis, karakterisasi, mekanisme kerja, dan hasil uji klinis yang relevan. Penggunaan nanopartikel lipid telah menunjukkan potensi besar sebagai penghantar obat yang efektif,  nanopartikel polimer menawarkan kontrol pelepasan obat yang lebih baik dan nanopartikel logam menawarkan sifat antimikroba intrinsik. dan Kesimpulannya review artikel ini akan mengulas secara menyeluruh berbagai penelitian mengenai penghantaran zat aktif terbarukan melalui nanoteknologi untuk terapi jerawat.
PENGARUH SONIKATOR PROBE TERHADAP FORMULASI NANOSTRUCTURED LIPID CARRIERS KURKUMIN MENGGUNAKAN LIPID PADAT PRECIROL®: EFFECT OF PROBE SONICATOR ON CURCUMIN NANOSTRUCTURED LIPID CARRIERS USING PRECIROL® SOLID LIPIDS Jafar, Garnadi; Pebriawati, Silpi; Latifah, Zahra Alfa; Pratama, Reza
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol. 25 No. 1 (2025): Jurnal Kesehatan Bakti Tunas Husada Volume 25 Nomor 1 Tahun 2025
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v25i1.1451

Abstract

Androgenetic Alopecia (AGA) merupakan jenis kebotakan yang sering terjadi pada pria dan wanita yang dipengaruhi oleh hormon dihidrotestosteron (DHT). Minoksidil dan finasterid merupakan terapi umum untuk pengobatan AGA. Namun, minoksidil dan finasterid dapat menyebabkan efek samping dermatologis seperti iritasi kulit, ruam, dan dermatitis kontak alergi maka diperlukan pengobatan alternatif untuk mengurangi efek samping yang ditimbulkan. Kurkumin dipilih karena efek antiandrogeniknya yang dapat menghambat steroid 5-alpha reductase sehingga dapat menurunkan hormon DHT yang berlebih dalam tubuh. Namun, kurkumin ini memiliki banyak keterbatasan diantaranya sukar larut dalam air, bioavailabilitas yang rendah, log P 2,56-3,29 dan mudah terdegradasi sehingga efektivitas pengobatan tidak optimal. Oleh sebab itu, diperlukan suatu sistem penghantaran obat yang tepat seperti Nanostructured Lipid Carriers (NLC) sehingga dapat meningkatkan efektivitas biologisnya. NLC merupakan generasi kedua nanocarrier lipid yang memiliki keunggulan dalam meningkatkan solubilitas, stabilitas, dan kapasitas pemuatan obat dibandingkan dengan Solid Lipid Nanoparticle (SLN). Tujuan penelitian ini yaitu untuk memformulasikan NLC kurkumin menggunakan Glyceryl palmitostearate, Capric triglyceride dengan 2 jenis surfaktan yang berbeda yaitu PEG-40 hydrogenated castor oil dan Decyl Glucoside. Metode penelitian yang digunakan untuk pembuatan NLC kurkumin ini yaitu high shear homogenization/sonicator probe yang dapat menghasilkan gelombang suara yang tinggi menyebabkan kavitasi sehingga ukuran partikel menjadi lebih kecil dan menciptakan gerakan turbulen yang dapat mempercepat proses pencampuran. Hasil penelitian menunjukkan bahwa NLC kurkumin dengan menggunakan surfaktan PEG-40 hydrogenated castor oil dan Decyl Glucoside memiliki karakteristik yang sesuai dengan ukuran partikel <400 nm, potensial zeta > ±20 mV, efisiensi penjerapan >80%, dan morfologi sferis. Dengan demikian, diharapkan NLC kurkumin dapat meningkatkan stabilitas dan bioavailabilitas kurkumin untuk memaksimalkan efektivitas pengobatan AGA.
Formulation and characterization of bay leaf extract nanophytosomes (Syzgium polyanthum) and affinity study of interaction with alpha glucosidase enzyme as antidiabetic Septianti, Regina Dwi; Jafar, Garnadi; Dinayanti, Westi Nur; Dinata, Deden Indra
Science Midwifery Vol 13 No 1 (2025): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i1.1888

Abstract

Introduction: Diabetes Mellitus is a metabolic syndrome disease in which around 90-95% of all cases of adults aged 20-79 years suffer from type 2 Diabetes Mellitus, with long-term conventional treatment causing side effects of hypoglycemia. Bay leaves which contain quercetin and kaempferol compounds are able to lower blood glucose levels, but have challenges in drug delivery due to easy oxidation and low bioavailability. Therefore, an innovative drug delivery system is needed, such as nanophytosomes, to increase its bioavailability. Objective: This study aims to develop a thin film formula of bay leaf extract nanophytosomes that have antidiabetic affinity with in silico studies and evaluate the physical characteristics of nanophytosomes. Method: in silico using the molecular docking method to evaluate the interaction of active compounds of bay leaves with the alpha glucosidase enzyme. Bay leaf nanophytosomes are formulated using heat homogenization and probe sonicator techniques. Characterization is carried out by measuring particle size, polydispersity index, zeta potential, and particle morphology. Results: The nanophytosome formula of bay leaf extract showed a particle size of <1000 nm, a polydispersity index of <0.5, and a zeta potential of ±25 mV. In silico studies showed that quercetin and kaempferol have a strong affinity for the α-glucosidase enzyme, which plays an important role in inhibiting glucose absorption. Conclusion: Bay leaf extract can be formulated into a phytosome-based nanoparticle delivery system that shows stable physical characteristics, high adsorption efficiency, and potential antidiabetic activity through the interaction of inhibiting the α-glucosidase enzyme.
Formulation and characterization of nanoemulgel of ethanol extract of bay leaves (Syzygium polyanthum) as an anti-burn agent using the hot plate method using white wistar rats Ningrum, Windi Pratama; Jafar, Garnadi; Pramudiahwardani, Ananda Rota; Kusriani, Herni
Science Midwifery Vol 13 No 1 (2025): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i1.1890

Abstract

Introduction: Wounds are tissue damage that can cause functional disorders and risk of infection. Effective wound management is essential to accelerate tissue regeneration and prevent complications. Bay leaf extract (Syzygium polyanthum) contains bioactive compounds such as flavonoids, tannins, and saponins that have anti-inflammatory, antibacterial, and wound healing activities. However, the limited bioavailability and skin penetration of these active compounds are challenges in topical therapy. Objective: This study aims to develop and evaluate a topical drug delivery system based on bay leaf extract nanoemulsion as an alternative therapy to accelerate wound healing. Method: Extraction was carried out using ethanol solvent, then formulated into a nanoemulsion with oil, surfactant, and co-surfactant components. Formulation characterization was carried out by measuring particle size, polydispersity index, zeta potential, and physical stability tests. Evaluation of effectiveness was carried out using a wound model in Wistar rats with the hot plate induction method. Wound healing observations were carried out clinically and histologically for a period of 14 days. Results: The formulation results showed that the nanoemulsion had a particle size of <200 nm, PDI <0.5, and zeta potential of ±25 mV, indicating good physical stability. Burn activity tests showed that topical administration of bay leaf extract nanoemulsion accelerated wound contraction, increased epithelialization, and improved tissue structure compared to the control group. Conclusion: Bay leaf extract can be formulated in a nanoemulsion-based nanoparticle delivery system that shows stable physical characteristics and is effective in accelerating wound healing.
Formulation and characterization of tretinoin nanosuspension and in silico testing as an anti-inflammatory Ramadhoni, M Ayodia; Jafar, Garnadi; Halizah, Arin Nur; Fatmawati, Fenti
Science Midwifery Vol 13 No 1 (2025): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i1.1892

Abstract

Introduction: Tretinoin is an effective retinoid derivative for acne therapy, but has formulation challenges due to its lipophilic nature and high crystallinity. An appropriate formulation strategy is needed to improve its stability and bioavailability. Objective: This study aims to evaluate the compatibility of tretinoin with excipients in nanosuspension formulations and their physicochemical characterization. Methods: Preliminary tests were carried out using Fourier Transform Infrared Spectroscopy (FTIR), crystallinity was analyzed by X-ray Diffraction (XRD), and thermal analysis by Differential Scanning Calorimetry (DSC). Nanosuspension characterization includes particle size, polydispersity index, zeta potential and entrapment efficiency. In silico test of the potential of tretinoin as a COX-2 inhibitor related to anti-inflammatory effects. Results: FTIR results showed no chemical interaction between tretinoin and excipients. XRD showed a decrease in tretinoin crystallinity after mixing with HPMC and PVP. DSC showed a shift in the melting point of tretinoin, indicating a physical interaction with excipients. Characterization of nanosuspension showed particle size <1000 nm, polydispersity index <0.5, zeta potential ±-20 mV, and entrapment efficiency >80%. In silico tests show that tretinoin has a binding energy of -9.57 kcal/mol against the Cyclooxygenase-2 (COX-2) enzyme with an inhibition constant of 96.03 nM. Conclusion: Tretinoin shows good compatibility and physicochemical characteristics in nanosuspension formulation, as well as potential as an anti-inflammatory agent through COX-2 inhibition.
REVIEW ARTIKEL: PENGEMBANGAN NANOSTRUCTURED LIPID CARRIERS UNTUK PENGOBATAN ALOPESIA Jafar, Garnadi; Pebriawati, Silpi; Latifah, Zahra Alfa; Pratama, Reza; Muhsinin, Soni
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.53560

Abstract

Alopesia androgenetik adalah bentuk kebotakan yang umum terjadi pada pria dan wanita, dipicu oleh faktor genetik dan hormonal, terutama dihidrotestosteron (DHT). Minoksidil dan finasterid adalah terapi yang paling sering direkomendasikan untuk mengatasi alopecia androgenetik; namun, pengobatan ini sering kali menghasilkan efek samping dermatologis, termasuk iritasi kulit, ruam, dan dermatitis kontak. Selain itu, metode pengobatan konvensional memiliki keterbatasan dalam penetrasi kulit dan efektivitas optimal. Oleh karena itu, dibutuhkan sistem penghantaran obat yang lebih efektif, seperti Nanostructured Lipid Carriers (NLC). Penelitian ini bertujuan untuk mengeksplorasi potensi NLC sebagai sistem penghantaran obat inovatif untuk alopecia androgenetik. Metode yang digunakan melibatkan literatur yang diperoleh dari platform seperti Google Scholar, ScienceDirect, dan PubMed. Data yang dikumpulkan dianalisis dan dikelola menggunakan Mendeley® untuk tujuan referensi. Temuan dari literatur menunjukkan bahwa NLC dapat meningkatkan penetrasi obat ke dalam folikel rambut, meningkatkan retensi obat di kulit, dan mengurangi efek samping. Temuan ini menegaskan potensi NLC sebagai sistem penghantaran obat yang menjanjikan untuk meningkatkan respons terapeutik dalam mengobati alopecia dan berbagai kondisi kulit lainnya.
Article review: Gastroretentive drug delivery system (GRDDS) in captopril Sutiyah, Siti; Jafar, Garnadi
Science Midwifery Vol 13 No 2 (2025): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i2.1920

Abstract

Captopril is an antihypertensive drug that belongs to the Angiotensin Converting Enzyme Inhibitor (ACE-Inhibitor) class and is widely applied for first-line therapy. This drug has a pharmacokinetic profile with a short half-life of about 2-3 hours, is easily soluble in water, and is stable under acidic conditions (pH 1.2). However, its stability decreases as the pH increases, making it susceptible to degradation. Absorption of captopril in the stomach does not take place completely due to the low gastro retention time (GTR), causing its bioavailability to be low (around 65%). To increase drug effectiveness, reduce degradation, and improve patient compliance, various drug delivery systems have been developed. One promising approach is the Gastroretentive Drug Delivery System (GRDDS), which is a sustained release drug delivery system deliberately designed to maintain the drug longer in the stomach. This review article aims to examine GRDDS methods that can be applied to captopril, including modification of the matrix and polymer used, in order to obtain a better drug release profile and improve drug characteristics. The literature review was searched using databases namely PubMed, Google Scholar, and Science Direct, with publication year coverage from 2014 to 2024. The keywords used included: “Gastroretentive Drug Delivery System (GRDDS)”.
Formulation and evaluation of thin film nanoemultion from rose flower ethanol extract (rosa hybrida hort.) and antidiabetes mellitus type 2 activity test using in vitro enzyme Gustana, Erick Kurniawan; Jafar, Garnadi; Aligita, Widhya; Nurfaiza, Putri; Hanaya, Cicia Rosa; Salsabilla, Syifa
Science Midwifery Vol 13 No 2 (2025): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i2.1969

Abstract

Diabetes mellitus is a chronic disease with a rising global prevalence. Natural antidiabetic agents derived from plant bioactive compounds offer a promising therapeutic alternative. Rose flowers (*Rosa hybrida Hort*) contain flavonoids such as kaempferol, known for their antidiabetic activity. However, poor solubility and bioavailability limit their therapeutic potential. This study aimed to develop and characterize a nanoemulsion of rose flower extract to enhance the stability and bioavailability of its active compounds. The extract was obtained by maceration using 96% ethanol and analyzed using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS). Nanoemulsion formulations were developed using various types and concentrations of nonionic surfactants. Characterization included particle size, polydispersity index (PDI), zeta potential, and morphology. The optimal nanoemulsion showed a particle size <300 nm, PDI <0.5, and zeta potential around ±20 mV, indicating good stability. Transmission Electron Microscopy (TEM) revealed uniformly distributed spherical globules. LC-MS/MS confirmed the presence of kaempferol as the main active compound. The formulated nanoemulsion was successfully incorporated into an oral thin film, exhibiting favorable characteristics such as appropriate particle size, PDI, zeta potential, morphology, and satisfactory evaluation results including organoleptic properties, moisture content, pH, weight uniformity, film thickness, folding endurance, and disintegration time.
Co-Authors Abdul Mulki Irpani Agung Laksono S, Moch Agus Sulaeman Agus Sulaeman Aligita, Widhya Aliyya Kurniasih Agustiani Aliza, Rieztya Amalia Putri, Amalia Anggraeni, Vina Juliana Ani Anggriani Arif Rubianto Ariqa Hidayatun Nisa Avianningsih, Reformia Bachrudin, Panji Buana Irviana Prita Choerrunisa, Choerrunisa Dadih Supriadi Damayanti, Hilda Deden I Dinata Deden Indra Dinata Deden Indra Dinata, Deden Indra Deny Puryani Devianti Sagita, Novaliana Dila Anggraeni Dinayanti, Westi Nur Dini Auliya Azmi Dwi C, Alya Elis Susilawati Elisabeth Weya Elsa Yunita Septiani Elvano, Deki Rifa Embas Saraswati, Dewa Ayu Emma Emawati, Emma ERISKA AGUSTIN Faisha Farras Kartanagara Fatmawati Fenti Fatmawati Karim Fatmawati, Fenti Fenti Fatmawati Fenti Fatmawati Fitriani, Ranti Ghea Nadira Shinta Gustana, Erick Kurniawan Halizah, Arin Nur Hanaya, Cicia Rosa Hasimun, Patonah Helen Fitri Novianti Herni Kusriani, R. Hidayat, Dudy Agustian Iceu Mulyati Iin Siti Aminah, Iin Siti Ira Adiyati Jajang Japar Sodik Karim, Fatmawati Khiong, Tjia Khie Kusriani, R Herni Latifah, Zahra Alfa Lia Marliani Mahran A, Ghani Maisyah, Aini Marita Kaniawati Meilani, Intan Mindiarto, Ahmad Bagus Muhamad Reza Pahlevi Muthmainah, Siti Saidah Ningrum, Windi Pratama Novaliana Devianti Sagita Novianti, Tamia Rizqi Nurfadillah, Rizal Nurfaiza, Putri Nurul Rahmalia Olivia Eka Putri Pahlevi, Muhamad Reza Pasha, ED Yunisa Mega Patonah, Patonah Pebriawati, Silpi Pramudiahwardani, Ananda Rota Pratama, Reza Priana, Eka Putriyanti Al-fira Putriyanti, Al-fira R. Awaludin Nazal N Rachmat Mauludin Rachmawati, Winasih Rahmat Santoso Raisya Salsabila Ramadhoni, M Ayodia Ratmoko, Sulthan Abdul Basith Ratu Fania Aprilyanti Reza Pahlevi, Muhamad Ria Riantini Riantini, Ria Rismawanti, Rusi Roganda Situmorang Rosyana, Nasywa Rusi Rismawanti Sagita, Novaliana Devianti Saifurrohman, Arip Saleh Wikarsa, Saleh Salsabilla, Syifa Sasanti Tarini Darijanto, Sasanti Tarini Senjaya, Fathurahman Ari Septianti, Regina Dwi Shelvy E Suherman Siti Jamilah Siti Raeyuni Maulidia Belina Siti Saidah Muthmainah Situmorang, Roganda Sofian, Ryan Soni Muhsinin Sukmawati, ika kurnia Susilawati, Elis Sutiyah, Siti Sutrisno, Entis Sutrisno, Entris Syarfa, Ahmad Syerliana Syerliana Tambunan, Irisanna Wahyu Wijayanti Wijaya, Teguh Pradinata Winasih Rachmawati Yani Mulyani Yani Mulyani Yolanda Putri Aloenida Yuyun Yuyun Zakaria, Hasballah Zakiyah, Nadhira Zalfa Dary Pernadi Ziska, Rahma