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All Journal Majalah Kedokteran Bandung Jurnal Kesehatan Andalas Jurnal Penelitian Kesehatan Suara Forikes Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Health and Medical Journal Human Care Journal Jurnal Ilmu Kesehatan Indonesia (JIKSI) Mandala of Health : A Scientific Journal Innovative: Journal Of Social Science Research Oftalmologi: Jurnal Kesehatan Mata Indonesia
Husnil Kadri
Universitas Andalas
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Public Health Veterinary Other

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Effect of High Fat and Cholesterol Diet on Total Blood Cholesterol Levels in Pregnant Wistar Rats Desmawati Desmawati; Annisa Yuda Mahdiyah; Husnil Kadri
Majalah Kedokteran Bandung Vol 55, No 1 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n1.2651

Abstract

Hypercholesterolemia during pregnancy is a physiological condition resulting from increased insulin resistance, lipoprotein synthesis, and lipolysis in adipose tissue, which mobilizes lipids as an energetic substrate for fetal growth. Consumption of foods high in fat and cholesterol may lead to an increase in total blood cholesterol levels during pregnancy due to saturated fat and cholesterol contents that will increases the synthesis of lipoproteins in the blood. The objectives of this study were to determine the effects of high fat and cholesterol diet on the total blood cholesterol levels in pregnant Wistar rats. This study was a true experimental research using a randomized post-test-only control group design  conducted from November 2020 to October 2021on fourteen female Wistar rats that were divided into control and intervention groups. Cow brain was provided as the high fat and cholesterol diet and after the rats gave birth, blood was drawn from the heart. The total blood serum cholesterol levels were assessed  using Micro Lab 300 with the CHOD-PAP method and the data were analyzed using an independent t-test. This study showed that the mean total blood cholesterol levels for the control and treatment groups were 80.43±18.512 mg/dL and  142.57±24.786 mg/dL, respectively, which reflected a significant differences in the mean total blood cholesterol level between the control and treatment groups (p-value <0.01). In conclusion, a high fat and cholesterol diet affects the total blood cholesterol level in pregnant Wistar rats.
ANALISIS FAKTOR RISIKO KEJADIAN DRY EYE DISEASE PADA TENAGA KEPENDIDIKAN FAKULTAS KEDOKTERAN UNIVERSITAS ANDALAS Febiyola Ratu Khairani; Hendriati Hendriati; Husnil Kadri; Kemala Sayuti; Tofrizal Tofrizal; Moestafa Nur
HUMAN CARE JOURNAL Vol 8, No 3 (2023): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v8i3.2691

Abstract

ABSTRAKDry eye disease (DED) atau penyakit mata kering merupakan penyakit multifaktorial pada mata yang memengaruhi penglihatan, aktivitas sehari-hari, produktivitas kerja, dan kualitas hidup secara umum sehingga penting untuk mengontrol faktor risiko yang dapat dimodifikasi. Penelitian ini bertujuan untuk mengetahui hubungan antara jenis kelamin, usia, penggunaan komputer, penggunaan ruangan ber-AC serta kebiasaan merokok dengan risiko kejadian dry eye disease pada tenaga kependidikan Fakultas Kedokteran Universitas Andalas. Metode yang digunakan adalah analitik observasional dengan desain penelitian cross sectional menggunakan kuesioner OSDI dengan uji korelasi Mann-Whitney dan Rank Spearman. Hasil penelitian menunjukkan bahwa terdapat hubungan yang signifikan antara usia (p=0,012) dan penggunaan komputer (p=0,000) dengan DED dimana dengan bertambahnya usia dan semakin lama durasi penggunaan komputer maka semakin tinggi risiko DED namun tidak terdapat hubungan yang signifikan antara jenis kelamin (p=0,877), penggunaan AC (p=0,463), dan kebiasaan merokok (p=0,206) dengan DED. ABSTRACTDry eye disease (DED) is a multifactorial disease that occurs on the eye. DED symptoms can affect vision, daily activities, productivity at work and general quality of life therefore the modifiable risk factors is important to control. This study was aimed to determined the relationship between gender, age, use of computers, use of air-conditioner rooms, and smoking habits to the risk of dry eye disease in educational staff at the Faculty of Medicine Universitas Andalas. The method used was an observational analytic with a cross sectional design was using the OSDI questionnaire with the Mann-Whitney correlation test and Spearman Rank correlation test. The results of the study showed that there was a significant relationship between age (p=0,012) and computer use (p=0,000) to DED, increasing age and the longer duration of computer use, the higher risk of suffer from dry eye disease but there was no significant relationship between gender (p=0,877), use of air-conditioner (p=0,463), dan smoking habits (p=0,206) to DED.
Correlation Between Visual Acuity and Severity Stages of Primary Angle-Clousure Glaucoma Nurul Syifa Kurnia; Husnil Kadri; Fitratul Ilahi
Oftalmologi : Jurnal Kesehatan Mata Indonesia Vol 6 No 1 (2024): Oftalmologi: Jurnal Kesehatan Mata Indonesia
Publisher : Pusat Mata Nasional Rumah Sakit Mata Cicendo Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ojkmi.v6i1.62

Abstract

Introduction: Primary Angle Closure Glaucoma (PACG) is a major contributor to global irreversible blindness due to the closure of the angle and subsequent intraocular pressure elevation. Preventing permanent angle closure becomes pivotal in averting blindness linked to PACG. Visual impairment in PACG may occur acutely or chronically. This study aims to investigate the impact of PACG severity, assessed through cup-to-disc ratio (CDR), on the visual acuity of affected patients. Objective: The primary objective is to assess the correlation between PACG severity stages, measured by CDR indicative of glaucomatous cupping, and visual acuity in PACG patients. Methods: Conducted as a cross-sectional observational study, this research took place at the Ophthalmology Outpatient Clinic of RSUP Dr. M. Djamil Padang. The study enrolled 50 patients meeting clinical criteria, and data were subjected to Spearman's correlation test, with significance set at p<0.05. Results: The majority of PACG patients (54%) either did not experience or had not experienced visual impairment, and most were classified under moderate PACG (64%). Bivariate analysis revealed a significant positive correlation between visual acuity and PACG severity based on CDR (r=0.709). Conclusion: This study establishes a significant positive correlation, indicating that greater CDR, reflecting increased PACG severity, is associated with poorer visual acuity. Recognizing this association is crucial for developing targeted interventions and preventing irreversible visual loss in PACG patients.
Correlation Between Visual Acuity and Severity Stages of Primary Angle-Closure Glaucoma Nurul Syifa Kurnia; Kadri, Husnil; Ilahi, Fitratul
Oftalmologi : Jurnal Kesehatan Mata Indonesia Vol 6 No 1 (2024): Oftalmologi: Jurnal Kesehatan Mata Indonesia
Publisher : Pusat Mata Nasional Rumah Sakit Mata Cicendo Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ojkmi.v6i1.62

Abstract

Introduction: Primary Angle Closure Glaucoma (PACG) is a significant cause of irreversible blindness worldwide. It is caused by the closure of the drainage angle in the eye, leading to increased intraocular pressure. This study investigates the relationship between PACG severity, as measured by cup-to-disc ratio (CDR), and visual acuity in patients with PACG. Objective: The primary objective is to assess the correlation between PACG severity stages, measured by CDR indicative of glaucomatous cupping, and visual acuity in PACG patients. Methods: Conducted as a cross-sectional observational study, this research took place at the Ophthalmology Outpatient Clinic of RSUP Dr. M. Djamil Padang. The study enrolled 50 patients meeting clinical criteria, and data were subjected to Spearman's correlation test, with significance set at p<0.05. Results: The majority of PACG patients (54%) either did not experience or had not experienced visual impairment, and most were classified under moderate PACG (64%). Bivariate analysis revealed a significant positive correlation between visual acuity and PACG severity based on CDR (r=0.709). Conclusion: This study establishes a significant positive correlation, indicating that greater CDR, reflecting increased PACG severity, is associated with poorer visual acuity. Recognizing this association is crucial for developing targeted interventions and preventing irreversible visual loss in PACG patients.
Pengaruh Ekstrak Etanol Peronema canescens Jack terhadap Ekspresi Gen Tumor Necrosis Factor Alpha pada Sel HeLa Ansharina, Hafiznie; Revilla, Gusti; Kadri, Husnil; Desmawati, Desmawati; Yusri, Elfira; Ali, Hirowati
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1418

Abstract

Latar Belakang: Kanker serviks merupakan kanker yang menduduki peringkat keempat pada wanita di seluruh dunia. Kanker ini disebabkan oleh Human Papillomavirus (HPV) tipe resiko tinggi yang menyerang sel-sel leher rahim. Sel kanker akan mensekresi Tumor Necrosis Factor Alpha (TNF-α) untuk menjadikan lingkungan mikrotumor mendukung bagi kelangsungan hidup sel kanker. Terapi kanker serviks yang umum digunakan adalah pembedahan, radioterapi, dan kemoterapi. Terapi lain yang juga digunakan adalah tanaman herbal, contohnya sungkai. Ekstrak etanol daun sungkai (Peronema canescens J) mengandung senyawa yang berperan sebagai antiinflamasi dan antioksidan. Tujuan: Penelitian ini bertujuan untuk mengetahui pemberian ekstrak etanol daun sungkai dalam menurunkan ekspresi gen TNF-α pada sel HeLa. Metode: Penelitian ini merupakan penelitian true experimental dengan post test only control group design yang menggunakan 24 well plate kultur sel HeLa yang tumbuh secara konfluens. Sampel dibagi menjadi empat kelompok (K, P1, P2, dan P3). Kelompok perlakuan diberikan ekstrak etanol daun sungkai dengan konsentrasi inhibition concentration (IC)25, IC50, dan IC75 yang diinkubasi selama 24 jam. Sel yang telah diberi perlakuan akan dipanen untuk dilakukan isolasi RNA. Pemeriksaan gen TNF-α dilakukan menggunakan PCR Konvensional, kemudian band elektroforesis berukuran 47 bp dianalisis menggunakan ImageJ. Hasil: Data didapatkan dari analisis ketebalan band elektroforesis yang diukur menggunakan ImageJ. Analisis data dilakukan menggunakan uji One Way ANOVA dan Post Hoc Bonferroni, didapatkan rerata ekspresi gen TNF-α pada kelompok K, P1, P2, dan P3 secara berturut-turut adalah 0,32; 0,29; 0,23; dan 0,14. Terdapat perbedaan yang bermakna antara kelompok K terhadap P2 dan P3 dengan nilai p=0,000 (p<0,05), sedangkan kelompok K dengan P1 perbedaannya tidak bermakna (p>0,05). Kesimpulan: Pemberian ekstrak etanol daun sungkai pada konsentrasi IC50 dan IC75 mampu menurunkan ekspresi gen TNF-α pada kelompok sel HeLa.
Correlation Of Neutrophil Lymphocyte Ratio And Platelet Lymphocyte Ratio With Severity Of COVID-19 Warman, Fadil Ahmadhia; Yulia, Dwi; Kadri, Husnil; Mulyana, Roza; Yusri, Elfira; Putra, Syandrez Prima
Majalah Kedokteran Andalas Vol 46, No 9 (2024): Supplementary Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i9.p1361-1375.2024

Abstract

The neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) tests are simple tests can be done before a COVID-19 patient hospitalized. This examination is useful for determining the diagnosis and prognostic of the patient. The aim of the study was to determine the correlation between NLR and PLR with the severity of COVID-19. This research was an analytical study with a cross-sectional approach using secondary data from 289 medical records of patients with confirmed COVID-19 for the period June-August 2021. The total sampling technique was used and processed with the chi-square test. Most of the research subjects were in the range of 26-45 years (28.4%). More than half of the subjects were female (61.6%). There were 99 patients (34.3%) with severe conditions. Less than half of the patients had abnormal leukocyte and platelet examination results, namely 64 (22.1%) and 56 (19.4%). Patients with abnormal NLR and PLR examinations were 135 (46.7%) and 123 (42.6%). There was a significant correlation between NLR and the severity of COVID-19 inpatients (p<0.001, OR=9.452). There is a significant correlation between PLR and the severity of COVID-19 inpatients (p<0.001, OR=7.268). This study concludes a significant correlation between NLR and PLR with the severity of COVID-19.
Perbedaan Prestasi belajar Pada Siswa dengan Adiksi, Adiksi Ringan, dan Non-Adiksi Game online di SMAN 15 Padang Astuti, Bunga; Liza, Rini Gusya; Kadri, Husnil
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1279

Abstract

Abstrak Latar Belakang: Adiksi game online adalah kecanduan dalam memainkan game online dan paling banyak terjadi pada usia remaja, serta dapat mempengaruhi prestasi belajar. Objektif: Penelitian ini bertujuan untuk mengetahui adanya perbedaan prestasi belajar pada siswa dengan adiksi, adiksi ringan, dan non-adiksi game online di SMAN 15 Padang. Metode: Penelitian ini merupakan penelitian analitik komparatif kategorik tidak berpasangan dengan pendekatan cross sectional. Teknik yang digunakan dalam pengambilan sampel adalah total sampling. Hasil: Hasil penelitian menunjukkan 28,1% siswa mengalami adiksi game online dengan rerata prestasi belajar siswa pada kategori cukup. Hasil uji Kruskal-Wallis menunjukkan terdapat perbedaan yang bermakna pada prestasi belajar antara siswa adiksi, adiksi ringan, dan non-adiksi game online. Hasil Mann-Whitney U Test menunjukkan terdapat perbedaan bermakna pada prestasi belajar antara siswa adiksi ringan dengan non-adiksi game online, serta tidak terdapat perbedaan bermakna pada prestasi belajar antara siswa adiksi dengan adiksi ringan game online dan adiksi dengan non-adiksi game online. Kesimpulan: Kesimpulan penelitian ini adalah terdapat perbedaan yang bermakna pada prestasi belajar antara siswa adiksi, adiksi ringan, dan non-adiksi game online, terutama pada prestasi belajar antara siswa adiksi ringan dengan non-adiksi game online. Kata kunci: Adiksi, game online, prestasi belajar Abstract Background: Online game addiction is an addiction to playing online games and most often occurs at the age of teenagers, and can affect learning achievement. Objective: This study aims to determined the differences in learning achievement in students with addiction, mild addiction, and non-addiction to online games at SMAN 15 Padang. Methods: This research is an unpaired categorical comparative analytic with cross sectional approach. The technique used in sampling was total sampling. Results: The results showed that 28.1% of students were addicted to online games with an average student achievement in the moderate category. The results of the Kruskal-Wallis test showed a significant difference in learning achievement between students with addiction, mild addiction, and non-addiction to online games. The results of the Mann-Whitney U test showed a significant difference in learning achievement between students with mild addiction to online games and non-addicted to online games, and there was no significant difference in learning achievement between students with mild addiction to online games and addiction to non-addiction to online games. Conclusion: The conclusion of this study is that there are significant differences in learning achievement between students with addiction, mild addiction, and non-addiction to online games, especially on learning achievement between students with mild addiction to online games and non- addicted to online games. Keyword: Addiction, online games, learning achievement
Korelasi Skor Aktivitas Fisik dengan Jarak 6-Minute Walking Test pada Mahasiswa yang Tidak Aktif Berolahraga Septi, Annisa; Hamdani, Rita; Kadri, Husnil
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 1 (2025): Maret 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i1.1384

Abstract

Latar Belakang: Kemajuan teknologi modern memberikan dampak positif berupa efisiensi waktu, namun juga berisiko negatif dengan meningkatkan gaya hidup sedentary, terutama pada generasi muda yang kurang bergerak, yang dapat menyebabkan peningkatan risiko Penyakit Tidak Menular (PTM) seperti hipertensi, obesitas, dan gangguan jantung, serta meningkatkan angka ketidakaktifan fisik di Indonesia dari 26,1% pada 2013 menjadi 33,5% pada 2018. Dalam sepuluh tahun terakhir, 6-minute walking test (6MWT) semakin populer digunakan untuk menilai kapasitas fungsional karena kesederhanaannya, tidak memerlukan peralatan canggih, mudah dilakukan, murah, tidak invasif, serta lebih mencerminkan aktivitas kehidupan sehari-hari dibandingkan tes berjalan lainnya. Objektif: Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik dengan jarak 6-minute walking test pada mahasiswa yang tidak aktif berolahraga. Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional. Teknik pengambilan sampel menggunakan teknik consecutive sampling dengan jumlah sampel sebanyak 51 sampel. Populasi penelitian ini adalah mahasiswa aktif program studi kedokteran Universitas Andalas. Hasil: Hasil penelitian diperoleh rerata skor aktivitas fisik mahasiswa yang tidak aktif berolahraga sebesar 1119,50 ± 936,9 MET-menit/minggu dan jarak 6-minute walking test sebesar 376,16 ± 55,08 meter. Hasil analisis bivariat menunjukkan bahwa terdapat korelasi positif antara skor aktivitas fisik dengan jarak 6-minute walking test dengan nilai p=0,000. Kesimpulan: Kesimpulan penelitian ini terdapat hubungan aktivitas fisik dengan jarak 6-minute walking test pada mahasiswa yang tidak aktif berolahraga. Mahasiswa dengan aktivitas fisik yang kurang mendapat hasil 6-minute walking test yang lebih rendah.  
UPAYA PENINGKATAN PENGETAHUAN TENTANG MAKANAN JAJANAN DAN PEMERIKSAAN GOLONGAN DARAH PADA MURID SD NEGERI 11 LOLONG BELANTI DI KECAMATAN PADANG UTARA Yustini Alioes; Husnil Kadri
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 3 No. 1 (2020)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v3i1.168

Abstract

Community service on the decision-making process in foreign policy aims to improve awareness of high school students in Padang on the importance of foreign policy. Foreign policy is often identified with complexity and far from public sphere. The community service team expects this activity could help high school students understand the decision making process in foreign policy. The community service is conducted with lecture and role-play method of formulating foreign policy. The approach used in this program is Graham Allison’s concept regarding process of foreign policy- making. This activity is designed in several stages. In the initial stages, the team prepares working plans. The second stage is socialization and the last stage is program implementation. It can be concluded that this community service has increased the student’s understanding in regards to the importance of foreign policy. Result of this activity indicates that students’ knowledge on foreign policy is improving. This is calculated based on several indicators i.e understanding on the role of actors in formulating foreign policy, factors affecting foreign policy and impact on the state’s strategy to pursue its national interest.
EDUKASI KESEHATAN DAN PEMERIKSAAN GOLONGAN DARAH PADA MURID SD NEGERI 13 DI DESA TUNGKAL SELATAN KECAMATAN PARIAMAN UTARA Yustini Alioes; Husnil Kadri; Eti Yerizel; Hirowati Ali; Rauza Sukma Rita; Desy Arisanti
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 4 No. 2 (2021)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v4i2.289

Abstract

Elementary school students are consumers who are among those who consume the most food and beverages. Food and drinks sold around the school contain many hazardous substances such as dyes that have been banned from circulating (Rhodamine B in iced drinks, jelly drinks, and so on) and other additives such as formalin which is used as a chewy substance in meatballs sold in carts and restaurants that can cause acute poisonings such as allergies, coughs and chronic poisonings such as cancer of the liver, kidneys and other organs. The purpose of this activity is to increase knowledge about substances in food and an introduction to blood group examination. This activity was carried out at SD Negeri 13 Tungkal Selatan Village in North Pariaman District. The method of activity is in the form of counseling and demonstration. According to the survey before the blood group examination, it turned out that most of the elementary school students did not know their blood type. Before the blood group examination, the students were also given knowledge about determining a person's blood type. After this counseling was carried out, respondents became more aware of the impact of food/snacks on health, and respondents knew their respective blood types. Of the 64 students, there are 22 A, 17 B, 12 AB, 13 O. To avoid problems related to food and blood type. There is a need for continuous health education for elementary school students.
Co-Authors Addina Fitri Islami Afifah Alfyanita Afifah Aqilatul Faridah Putri Wirza Afriwardi Afriwardi Almurdi Almurdi Anggy Afriani Annisa Yuda Mahdiyah Ansharina, Hafiznie Aristya Rahadiyan Budi Astuti, Bunga Aswiyanti Asri Azzahra Velia Delmi Sulastri Desmawati Desmawati Desmiwarti Desmiwarti Desrida Desrida Dessy Arisanty Desy Arisanti Desy Arisanti Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Dina Arfiani Rusjdi Efrida Efrida Elmatris Elmatris Elmatris Sy Endrinaldi Erlina Rustam Eti Yerizel Ezy Julianx Jarit Fathiyyatul Khaira, Fathiyyatul Fauzan Arisyi Koto Febiyola Ratu Khairani Febria Prima Utari Gusti Revilla Hadi Oktafiano Harris Putra Reza Hendriati, Hendriati Heri Fitrianto Hildya Kusmi Hirowati Ali Hirowati Ali, Hirowati Husna Yetti Ilahi, Fitratul Indah Lisfi Julizar Julizar Kemala Sayuti Kencana, Gita Kirbi Vira Akesa Mahata, Liganda Endo Mayetti Mayetti Mazara, Fitria Merisca Gayatri Ryosa Miftah Irramah Miftah Nur Andamsari Millah Fithriyah Zindany Moestafa Nur Muhammad Fadli Mulfa Satria Asnel Nadhira Isza Qushoyyi Noverial, Noverial Nur Indrawati Lipoeto Nursal Asbiran Nurul Syifa Kurnia Nurul Syifa Kurnia Nuzulia Irawati Pratiwi Dian Pramana Putri, Biomechy Oktomalio Rahmani Welan Rahmat Feryadi Rana Zara Athaya Ranti Verdiana Rauza Sukma Rita Rini Gusya Liza, Rini Gusya Rita Hamdani Rose Dinda Martini Rosfita Rasyid Roza Mulyana Saptino Miro, Saptino Septi, Annisa Susila Sastri Syahrul, Muhammad Zulfadli Syaiful Azmi Syandrez Prima Putra Tofrizal Tofrizal Tofrizal Tofrizal Warman, Fadil Ahmadhia Yulia, Dwi Yusri, Elfira Yustini Alioes Yustini Alioes