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All Journal Jurnal Ilmiah Farmasi Jurnal Farmasi Klinik Indonesia MPI (Media Pharmaceutica Indonesiana) Jurnal Kimia Riset Jurnal Kesehatan Jurnal Surya Medika JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Journal of Dedicators Community JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Farmasi Indonesia Jurnal Mandala Pharmacon Indonesia Jurnal Biomedika Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ners Jurnal Aisyah : Jurnal Ilmu Kesehatan JURPIKAT (Jurnal Pengabdian Kepada Masyarakat) Jurnal Farmasi dan Sains Indonesia (JFSI) Natural Sciences Engineering and Technology Journal Open Access Indonesian Journal of Medical Reviews Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Pharmaceutical Education Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Jurnal Ilmiah Kesehatan (JIKA) Jurnal Multidisiplin Madani (MUDIMA) Medical Sains : Jurnal Ilmiah Kefarmasian Formosa Journal of Science and Technology (FJST) Jurnal Farmasi Sains dan Praktis Proceeding of International Conference Health, Science And Technology (ICOHETECH) Journal of Advances in Medicine and Pharmaceutical Sciences Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Journal of Health Management and Pharmacy Exploration (JOHMPE) Medical Sains : Jurnal Ilmiah Kefarmasian International Journal of Contemporary Sciences (IJCS) Jurnal Ilmiah Multidisiplin Keilmuan Mandira Cendikia (JIMK-MC) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Jason Merari Peranginangin
Department Of Pharmacy Sciences, Faculty Of Pharmacy, Universitas Setia Budi Surakarta, Surakarta, Indonesia
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Dagusibu, P3K (Pertolongan Pertama Pada Kecelakaan) di Rumah dan Penggunaan Antibiotik yang Rasional di Kelurahan Nusukan Ika Purwidyaningrum; Jason Merari Peranginangin; Mardiyono Mardiyono; Jamilah Sarimanah
Journal of Dedicators Community Vol 3, No 1 (2019)
Publisher : Universitas Islam Nahdlatul Ulama Jepara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.582 KB) | DOI: 10.34001/jdc.v3i1.782

Abstract

The purpose of the service activity is to provide information and education to the public about dagusibu, P3K at home and rational use of antibiotics. Health counseling is needed by the community because it is known that the community. The GKSO Movement (Conscious Family Movement) is a program launched by the Indonesian Pharmacists Association (IAI) which is an effort to improve public understanding of medicines through dissemination of medicines, Dagusibu (Get, Use, Save and Dispose) medical equipment, medicine first aid treatment, and knowledge of antibiotics. The service partner, a resident of RT 08 RW 14, lacks awareness in maintaining cleanliness and still does not know the symptoms caused by an illness. The results of dedication show that citizens gain new knowledge and understand the material provided as a purpose of service
Fenofibrate Characterization of Solid Lipid Nanoparticles Using the High Shear Homogenization Method Muhimmatul Khoiriyah; Jason Merari Perangirangin; Ilham Kuncahyo
Natural Sciences Engineering and Technology Journal Vol. 2 No. 2 (2022): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v2i2.21

Abstract

Fenofibrate is a drug that can be used to treat hyperlipidemia where the drug is included in the category of Biopharmaceutical classification system II with poor solubility and high permeability. This causes the need to improve the drug delivery system (DDS) made using the solid lipid nanoparticle (SLN) method. SLN fenofibrate can be made using the high shear homogenization method by determining the formula using Factorial 22 Design Expert 12. The formula is made with a concentration of 0.31-1.25% GMS and 1.25-2% Tween-40, then SLN fenofibrate is made by mixing all ingredients until an emulsion is formed and continued with the SLN critical parameter test. From the test results, the critical parameters of SLN fenofibrate for the particle size of 8 formulas 490; 561; 601; 697; 916; 1040; 1818, and 2410 nm. The results obtained for the polydispersity index, respectively, were 0.02; 0.04; 0.08; 0.30; 0.35; 0.48; 0.51, and 0.65. The zeta potential value of the 8 formulas obtained successive values of 2.8; 3.5; 4.2; 4.8; 5.5; 5.8; 8.1, and 8.8 mV. Calculation of the efficiency of the SLN fenofibrate drug obtained successive values of 77.23; 78.53; 79.51; 80.47; 81.17; 87.38; 87.39, and 87.82%. The SLN method can improve drugs that are included in the Biopharmaceutical classification system class II category with the distribution of test results in the particle size range, and the adsorbed drug is more than 70%.
Antibacterial Activity of Moringa Plants (Moringa oleifera Lam.) to Overcome Antibiotic Resistance: A Systematic Review Novitarini; Jason Merari P.; Dian Marlina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 10 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i10.591

Abstract

Antibiotic resistance This causes the performance of synthetic antibiotics to decrease, so it is necessary to search for natural antibiotics. Moringa plant (Moringa oleifera Lam.) has antibacterial activity proven to inhibit and kill pathogenic bacteria and Multi-Drug Resistance (MDR)article review aims to collect data related to testing the antibacterial activity of Moringa plants as an effort to overcome antibiotic resistance. The method follows the PRISMA-2020 protocol by searching data on PubMed and ScienceDirect media using the keywords: "Antibacterial activity" and "Moringa oleifera". The data selection uses the Rayyan application by considering the inclusion and exclusion criteria that have been set. The final results obtained are 95 data which are experimental journals of the Randomized Control Trial (RCT) type published in 1981-2021. Moringa plants began to be investigated for their activity against MDR bacteria in 2012 and became a sign that research was already in the direction of finding solutions. Antibacterial testing was carried out in vitro (10 studies) and in vivo (1 study). The leaves have been thoroughly tested for their activity against Methicillin-Resistant Staphylococcus aureus (MRSA). The results of in vitro study obtained the range of zone of inhibition, minimum inhibitory concentration, and minimum kill concentration, respectively: 8.3-12 mm; 0.25-20 mg/ml; 0.50-20 mg/ml study in vivo showed that there was the healing of MRSA infection wounds in test animals.
Antibacterial Activity of Moringa Plants (Moringa oleifera Lam.) to Overcome Antibiotic Resistance: A Systematic Review Novitarini; Jason Merari P.; Dian Marlina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 10 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i10.591

Abstract

Antibiotic resistance This causes the performance of synthetic antibiotics to decrease, so it is necessary to search for natural antibiotics. Moringa plant (Moringa oleifera Lam.) has antibacterial activity proven to inhibit and kill pathogenic bacteria and Multi-Drug Resistance (MDR)article review aims to collect data related to testing the antibacterial activity of Moringa plants as an effort to overcome antibiotic resistance. The method follows the PRISMA-2020 protocol by searching data on PubMed and ScienceDirect media using the keywords: "Antibacterial activity" and "Moringa oleifera". The data selection uses the Rayyan application by considering the inclusion and exclusion criteria that have been set. The final results obtained are 95 data which are experimental journals of the Randomized Control Trial (RCT) type published in 1981-2021. Moringa plants began to be investigated for their activity against MDR bacteria in 2012 and became a sign that research was already in the direction of finding solutions. Antibacterial testing was carried out in vitro (10 studies) and in vivo (1 study). The leaves have been thoroughly tested for their activity against Methicillin-Resistant Staphylococcus aureus (MRSA). The results of in vitro study obtained the range of zone of inhibition, minimum inhibitory concentration, and minimum kill concentration, respectively: 8.3-12 mm; 0.25-20 mg/ml; 0.50-20 mg/ml study in vivo showed that there was the healing of MRSA infection wounds in test animals.
Analisis Proses Pengelolaan Obat Dengan Pendekatan Lean Hospital Di RSUD X Kabupaten Jombang Muhamad Aulia Putra Tawakal; Jason Merari Peranginangin; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i2.1032

Abstract

The lean approach can make hospitals become more organized so they can improve the quality of services to patients by reducing waste, including the occurrence of errors, movements, transportation and poor service flow that leads to long service waits which certainly is not expected by patient. The purpose of this study was to identify the waste and the root causes of waste that occurred in the Pharmacy Installation at RSUD X Jombang. This research method is a qualitative descriptive study. The stages of the research are the observation of the drug management process flow which is made in the form of value stream mapping, focus group dicussion, and fishbone diagrams to determine the root cause of the problem. The results showed that the waste in the procurement process of 96.07% included in the category of necessary but non-value added, the acceptance process amounted to 62,59% of activities included in the category of necessary but non-value added, in the storage process there was a waste of 53, 39% included in the category of non value added, and in the process of using waste by 36.22% included in the category of non value added. The root cause of the problem of procurement is the length of time it takes to request the approval of PPK and PPTK, at the reception there is no specific place for receipt of goods, in storing all records and reporting is still manual and in use there is only one prescription receipt and delivery of drugs. In the future state mapping it is known to save time by 45.60% on procurement, 58% on revenue, 53.39% on storage, and 69% on usage.
STUDI LITERATUR: JENIS SEDIAAN, SIFAT FORMULASI, DAN NILAI ANTIOKSIDAN TERBAIK LIP CREAM EKSTRAK BIJI COKLAT (Theobroma cacao L) METODE UJI DPPH: LITERATURE STUDY: TYPES OF FORM, FORMULATION PROPERTIES, AND BEST ANTIOXIDANT VALUE OF LIP COCOA BEEN EXTRACT (Theobroma cacao L) DPPH TEST METHOD Mohammad Fauzy R. Syahruddin; Jason Merari; Endang Diyah Ikasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 4 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i4.531

Abstract

Biji coklat (Theobroma cacao L,) memiliki kandungan antosianin yang berpotensi sebagai antioksidan alami untuk diformulasikan dalam sediaan lip cream. Antioksidan merupakan molekul penghambat oksidasi yang dapat melindungi kulit dari kerusakan karna radiasi dan UV. Penelitian ini bertujuan ntuk mengetahui hasil uji aktivitas antioksidan tertinggi formulasi kakao pada berbagai jenis bentuk sediaan menggunakan metode uji DPPH serta sifat formulasi fisik yang dihasilkan secara review literatur. Metode penelitian ini adalah literatur review atau tinjauan pustaka. Jurnal penelitian yang sesuai dengan kriteria inklusi (hasil uji aktivitas antioksidan dengan metode uji antioksidan (DPPH) pada cacao) kemudian dikumpulkan dan dibuat ringkasan jurnal. Ringkasan jurnal penelitian tersebut dimasukan ke dalam tabel diurutkan sesuai alphabet dan tahun terbit jurnal. Berdasarkan hasil review literatur yang dilakukan oleh peneliti menghasilkan berbagai jenis formulasi, bentuk sediaan, sifat fisik yang dihasilkan dan nilai uji aktivitas antioksidan. Pada literatur review yang diperoleh dapat disimpulkan bahwa penelitian internasional yang dilakukan oleh Kasparaviciene et al, (2016) dalam mengevaluasi aktivitas antioksidan lipstik menghasilkan % inhibisi DPPH sebesar 59,8% ± 1,15 (diperoleh aktifitas antioksidan yang sangat kuat) dengan menggunakan formulasi Sea buckthorn oil (11.66) dan Grapeseed oil (6.00), sedangkan penelitian dengan nilai uji antioksidan terendah adalah pada penelitian Marlina (2019) yaitu senilai IC 50 0,008 mg/ml dengan formulasi krim menggunakan setil alkohol 16%. Sifat fisik yang dihasilkan pada penelitian Kasparaviciene et al, (2016) adalah baik dan homogen.
Potensi Enzim Superoksida Dismutase dari Biji Jagung (Zea Mays L.) untuk Perbaikan Sel Fibroblas 3t3 Yang Dipaparkan Sinar Ultraviolet A Mustika Endah Pratiwi; Jason Merari Peranginangin; Isna Jati Asiya; Ana Indrayati
Jurnal Ilmiah Farmasi Vol. 18 No. 2 (2022): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol18.iss2.art16

Abstract

Background: UV-A radiation induct disorder to the skin called photoaging. It requires treatment with antioxidant agent. Superoxide dismutase (SOD) is the first line antioxidant in the treatment of free radicals.  Objective: This study aimed to find out anti-photoaging activities of SOD extract of corn (Zea mays L.) kernels on radiated UV-A rays 3T3 fibroblast cells. Method: SOD extraction of corn kernels was done by centrifugation, precipitation and dialysis method. The activity of SOD extract in corn kernels was measured by WST-1 method. Anti-photoaging activity test of SOD extract in corn kernels was done on radiated UV-A rays 3T3 fibroblast cells with parameters of cell viability. Anti-photoaging activity test using cell control, negative, sample and positive control.   Results: SOD activity showed that the highest percent inhibition value was SOD extract of corn kernels in precipitation of ammonium sulphate concentration was 60-90% with inhibition percentage was 65.50%. The result of anti-photoaging activity SOD extract of corn kernels showed significant difference in the value of percent cell viability in fibroblast cells between the extract group and the negative control group with the highest percent cell viability in SOD extract corn kernels with the concentration was 100 mg/mL, namely 142.31%. Conclusion: SOD extract from corn kernels has proven had antioxidant activity that could be used as anti-photoaging through fibroblast cell reparation mechanism.
Ethnomedicin Studies and Antimicrobial Activity Tests of Plants Used in The Tengger Tribal Community Yaya Sulthon Aziz; Jason Merari Peranginangin; Titik Sunarni
Proceeding of International Conference on Science, Health, And Technology Proceeding of the 1st International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.893 KB) | DOI: 10.47701/icohetech.v1i1.792

Abstract

Based on the medicinal plants used by the Tengger tribe and their vulnerability to antibiotic resistance, it is necessary to develop new antimicrobial drugs that are sourced from natural ingredients. This study is to determine the use of plants as a traditional medicine in the Tengger tribe which has the potential as an antimicrobial. Determination of informants in the Tengger Tribe with snowball sampling. Antimicrobial plants that have UV and ICF values close to 1 macerated with 96% ethanol. Ethanol extract, water fraction, ethyl acetate fraction and n-hexane fraction were made at concentrations of 40, 20, 10, 5, and 2.5%. Antimicrobial test by dilution method, each concentration was tested on Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, and Candida albicans. The results showed 31 types of disease, 47 medicinal plants and 60 traditional ingredients in the Tengger tribe. Based on UV and ICF values 9 types of antimicrobial diseases and 4 potential medicinal plants were obtained. Antimicrobial medicinal plants used are Radicula armoracia, Artemisia vulgaris, Prunus persia, and Rapanus raphanistrum. Antimicrobial activity is best shown in the fraction n-hexane in all test plants. The four medicinal plants used by the Tengger tribe have the potential to be new antimicrobials
PENDEKATAN LEAN HOSPITAL UNTUK MENINGKATKAN EFISIENSI PELAYANAN INSTALASI FARMASI RAWAT JALAN DI RSUD TOBELO: LEAN HOSPITAL APPROACH IN IMPROVING SERVICE EFFICIENCY IN AMBULATORY PATIENT PHARMACEUTICAL INSTALLATION IN RSUD TOBELO Sisca Latue; Jason Merari Peranginangin; Tri Wijayanti
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.608

Abstract

Pendekatan lean adalah metode pendekatan sistemik yang digunakan untuk menghilangkanatau meminimalkan waste yang terjadi dalam pelayanan dan meningkatkan efesiensipelayanan di suatu instalasi. Tujuan penelitian ini untuk mengidentifikasi waste dan akarpenyebab waste yang terjadi pada Instalasi Farmasi Rawat Jalan (IFRJ) RSUD Tobelo. Metodepenelitian ini adalah penelitian non-esperimental dengan pendekatan kualitatif secaradeskriptif eksploratif melalui kuesioner, observasi dan wawancara mendalam pada responden.Prosedur penelitian yaitu observasi alur proses pelayanan yang dibuat dalam bentuk valuestream mapping, penyebaran kuisioner value pasien dan waste, melakukan wawancara denganmetode 5 why untuk mengetahui akar penyebab dan waste kritis, serta usulan terhadappemecahan masalah. Hasil penelitian menunjukan bahwa waste kritis berupa waste waitingyang diperoleh nilai sebesar 25%. Akar penyebab dari waste waiting adalah kekurangansumber daya manusia, serta pembagian kerja bagi tenaga kefarmasian belum maksimal,sehingga menyebabkan penumpukan resep obat. Usulan perbaikan waste waiting adalahpenambahan sumber daya manusia serta penerapan SOP dalam pelayanan, selain itu jugamenambah unit computer dan printer. Kata kunci : Lean hospital, Instalasi Farmasi, RSUD Tobelo, Waste kritis, perbaikanpelayanan
Uji Aktivitas Antihipertensi Ekstrak Dan Fraksi-Fraksi Daun Matoa Pada Tikus Jantan yang Diinduksi Angiotensin II dengan Parameter Kadar Renin dan Angiotensin II Iyem Shahira; Jason Merari; Ika Purwidyaningrum
Jurnal Farmasi Indonesia Vol 20 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v20i1.926

Abstract

ABSTRACT Matoa leaves (Pometia pinnata) is a plant thought to have hypertensive activity because it contains kuersetin. Research conducted by (Purwidyaningrum, 2017) extracts and fractions of matoa leaves has antihypertensive activity with an effective dose of 150 mg/kg. Other studies conducted by (Elisa, 2019) effects that can reduce blood pressure are extract doses of 300 mg and 30 mg of ethyl acetate fraction induced by angiotensin II can reduce systolic and diastolic blood pressure. This study aims to determine extracts and fractions of matoa leaves in decreasing renin levels and angiotensin II levels. The extraction method was maseration with 96% ethanol solvent and fractionated by liquids method using n-hexane solvent, ethyl acetate water. In this study used 21 male wistar strain rats divided into 7 groups, namely group I (normal), group II as negative control (CMC 1%), group III as positive control (Irbesartan), group IV (matoa leaves extract 60 mg/200g), Group V (fraction n-hexane 2,34 mg/200g), Group VI (ethyl acetate fraction 9,54 mg/200g), Group VII (water fraction 7,98 mg/200g). The results showed ethanol extract and matoa leaves fractions were not significantly difference in meaning with the positive control group different in reducing blood pressure, renin levels and angiotensin II induced by angiotensin II and were significantly from the normal and negative group. The water fraction (7,98 mg/200g) showed a decrease in systolic blood pressure of 9.0% and diastolic 7.1%, the ethyl acetate fraction showed a decrease in renin level 0f 23.6 %. EDM showed a decrease in 17.2% angiotensin II levels. Keyword : Pometia pinnata; renin levels; angiotensin II levels; induced angiotensin II
Co-Authors Ahmad Nuzulul Abid Aljufri Mahmud Aminudin Ana Indrayati Andre Kurniawan Antoro, Sutopo Edy Argo Widianto arikha ayu susilowati Aryani, Norsarida Astuty, Meilinda Windy Atalia Tamo Ina Bulu Boedirahardja, Partana Chairun Darmawan, Nopandi Wisnu Desi Alviona Dewi Ekowati Dewi, Lucia VIta Inandha Dewi, Lucia Vita Inandha Dewi, Lutfiana Aswindra Diah Kartika Putri Dian Marlina Dwiannur, Febriandi Ramadhan Endang Diyah Ikasari Felix Imanuel Rachman Fitriarahmah, Giyan Gede Trima Yasa Gede Trima Yasa Gunawan Pamudji Widodo Harsono, Samuel Budi Ika Purwidyaningrum Ilham Kuncahyo Ismi Rahmawati Isna Jati Asiya Iswandi Iswandi Iyem Shahira Julia Megawati Djamal Keswara, Yane Dila Khofifah Maharani Lutfi Nofitasari Magdalena Retnoningsih Mardiyono Marlina, Dian Melviani Meyvie Belinda Kendage Mohammad Fauzy R. Syahruddin Muhamad Aulia Putra Tawakal Muhimmatul Khoiriyah Munawarah Munawarah Muslihatin, Muslihatin Mustika Endah Pratiwi Najmah Salsabila Narimo Nia Azzahra Nofika Dwi Anitasari Novitarini Novitarini Nur Anggreini Dwi Sasangka Oentari, Octaviana Dyah Onny Ziasti Fricilia Opstaria saptarini Prasojo Pribadi Prayitno, Krisdita Sundari Putri Pudiastuti RSP R.F.X Premihadi Putra Rahmawati, Ismi Reslely Harjanti Riskayanti Rizal Maarif Rukmana, Rizal Maarif Sabda Wahab Sarimanah, Jamilah Sawal, Rizky Ardian Hartanto Sholehah, Faza Putri Farihatus Sisca Latue Sofia, Anna Sri Rejeki Handayani Sudarwati, Vivid Latri Sulaiman, Teuku Nanda Saifullah Susanti, Kharisma Dewi Fadia Syamsul Ma'arif Titik Sunarni Titik Sunarni Tri Murti Andayani Tri Wijayanti Tri Wijayanti Widhoretno Puspandari Windi Antika Wiratantri, Fitra Indah Wiwin Herdwiani Wiwin Herdwiani Yaya Sulthon Aziz Yurita Werdiningsih Hutami