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All Journal Jurnal Ilmiah Farmasi Jurnal Farmasi Klinik Indonesia MPI (Media Pharmaceutica Indonesiana) Jurnal Kimia Riset Jurnal Surya Medika JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Journal of Dedicators Community Jurnal Farmasi Indonesia Jurnal Mandala Pharmacon Indonesia Jurnal Biomedika Jurnal Ners Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Farmasi dan Sains Indonesia (JFSI) Natural Sciences Engineering and Technology Journal Open Access Indonesian Journal of Medical Reviews Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Pharmaceutical Education Jurnal Ilmiah Kesehatan (JIKA) Jurnal Multidisiplin Madani (MUDIMA) Medical Sains : Jurnal Ilmiah Kefarmasian Formosa Journal of Science and Technology (FJST) Jurnal Farmasi Sains dan Praktis Jurnal Permata Indonesia Proceeding of International Conference Health, Science And Technology (ICOHETECH) Eduvest - Journal of Universal Studies Journal of Advances in Medicine and Pharmaceutical Sciences Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Journal of Health Management and Pharmacy Exploration (JOHMPE) Medical Sains : Jurnal Ilmiah Kefarmasian International Journal of Contemporary Sciences (IJCS) Jurnal Ilmiah Multidisiplin Keilmuan Mandira Cendikia (JIMK-MC) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Jurnal Kesehatan Indonesian Journal of Global Health Research
Jason Merari Peranginangin
Department Of Pharmacy Sciences, Faculty Of Pharmacy, Universitas Setia Budi Surakarta, Surakarta, Indonesia
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Evaluation of Vaccine Stock Management at the Karanganyar Regency Health Service Indonesia Kurniawan, Andre; Jason Merari Peranginangin; Samuel Budi Harsono
Open Access Indonesian Journal of Medical Reviews Vol. 4 No. 1 (2024): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v4i1.506

Abstract

Vaccines are very susceptible to damage, so vaccine management requires special handling, this is done to maintain vaccine quality. The aim of this research is to find out the description and evaluate suitability vaccine management at the Karanganyar Regency Health Service (DKK) in 2022 based on Minister of Health Regulation No. 12 of 2017. This research is a qualitative descriptive non-experimental research. These research methods cross sectional by using approach, observation or data collection. The sampling technique uses accidental sampling by reviewing and evaluating vaccine management, which includes planning, procurement, receipt, storage, and distribution at the Karanganyar Health Service. The method used for data collection uses checklist suitability and in-depth interviews with the Head of Installation and pharmacy officers. Vaccine planning is adjusted to the usage index and needs in the previous year using a combined method system top to bottom and bottom up. Vaccine procurement is centralized at the Provincial Health Service, where requests are made by method bottom up. Receiving the vaccine is not immediate drop from the center/province, but the Karanganyar DKK takes the needed vaccines to the Provincial Health Service using the provisions for good drug distribution methods. Vaccine storage and distribution at DKK Karanganyar is in accordance with Minister of Health Regulation number 12 of 2017 and also in accordance with vaccine management guidelines from the Ministry of Health in 2021. Vaccines at DKK Karanganyar are in accordance with Minister of Health Regulation number 12 of 2017 and also in accordance with vaccine management guidelines from the Ministry of Health in 2021, both in planning, procurement, receipt, storage and distribution.
Effect of Ethanol Extract and Fractions of Saluang Balum Root Lavanga Sarmentosa (Blume) Kurz) on Aphrodisiac Activity and Spermatogenesis in Hyperglicemia Rats Dwiannur, Febriandi Ramadhan; Peranginangin, Jason Merari; Saptarini, Opstaria
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 2 (2024): Volume 6 Nomor 2 Agustus 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i2.848

Abstract

High blood glucose levels or hyperglycemia can increase reactive oxygen species (ROS). Complications of secondary diabetes mellitus in the form of sexual dysfunction and impaired fertility in men. This is one of the causes of decreased sexual desire and sperm count, which can cause infertility in men. Saluang balum root (Lavanga sarmentosa (Blume) Kurz) with flavonoid, steroid, and tannin compounds is a traditional medicine that has the potential as an aphrodisiac and spermatogenesis. The purpose of this study was to obtain a histological picture of the seminiferous tubules, a decrease in blood glucose levels, aphrodisiac activity, and spermatogenesis. This study used 35 male wistar rats which were divided into 7 groups, normal group, negative control (CMC Na 1%), positive control (pasak bumi), ethanol extract of saluang balum root at a dose of (225 mg/kgBW), n-hexane fraction. (19.81 mg/kgBW), ethyl acetate fraction (64.5 mg/kgBW) and water fraction (140.67 mg/kgBW). All of these groups were induced by alloxan (100 mg/kgBW), except the normal group. The extracts and fractions were given for 14 days, then observed a decrease in blood glucose levels, aphrodisiacs, spermatogenesis and histological features in the seminiferous tubules. The results showed that the extract and fractions of saluang balum root had reduced blood glucose levels, aphrodisiac and spermatogenesis in hyperglycemic rats.
Analysis of BPJS Drug Inventory Control Using ABC-VEN Methods at Dr. Moewardi Surakarta Hospital in 2023 Suhailah, Dhia; Peranginangin, Jason Merari; -, Iswandi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.99658

Abstract

Background: The implementation of JKN by BPJS Kesehatan, drug inventory management has become a crucial thing to ensure the efficiency and effectiveness of healthcare services. However, delays in BPJS claims these payments often disrupt drug procurement in hospitals. This study is aimed to prevent stock outs so that an effective inventory control method is needed at Dr. Moewardi Surakarta Hospital.Objectives: This study is aimed to analyze the management of BPJS drugs at the Pharmacy Installation of Dr. Moewardi Surakarta Hospital using the ABC-VEN, dan EOQ methods to optimize inventory control, ordering, and, storage.Methods: This descriptive-analytical study used retrospective data from pharmacy record documents, inventory systems, stock levels, usage, costs, and interview results. Data accuracy was ensured through triangulation, cross-checking records with financial documents, and respons of interviews in 2023. The inventory value was calculated by multiplying the quantity of drugs procured and remaining stock (on their own puchasing prices) at the end of the year. Inventory Turnover Ratio  was calculated by dividing the COGS by the average inventory value. The data were analyzed using Microsoft Excel software version 2021.Results: Findings showed that ABC-VEN methods were 8% of drugs which were classified as AV, 6% as BV, 43% as CV, 5% as AE, 5% as BE, and 57% as CE out of 288 items, with CE dominating. The final inventory value was Rp 6,947,818,985 with an ITOR of 7.53 times per year.Conclusion: The findings show that the ABC-VEN method can improve inventory control, reduce stockouts, and align drug procurement with finance.
Pendekatan Lean Hospital untuk Mengidentifikasi Waste Kritis di Pelayanan Instalasi Farmasi Rawat Jalan RSUD Soehadi Prijonegoro Sragen Krisdita Sundari Putri Prayitno; Jason Merari Peranginangin; Ismi Rahmawati
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.40982

Abstract

Pendekatan lean adalah metode pendekatan sistemik yang digunakan untuk menghilangkan waste yang terjadi dalam pelayanan dan meningkatkan efesiensi pelayanan di suatu instalasi. Proses pelayanan kesehatan disuatu rumah sakit terdapat banyak sekali pemborosan terjadi, contohnya mengulangi kegiatan untuk perbaikan diakibatkan adanya kesalahan, meminta pasien untuk menginformasikan data pasien secara berulangkali untuk memastikan ketetapan informasi, dan sebagainya. Tujuan penelitian ini untuk mengidentifikasi waste dan akar penyebab waste yang terjadi di dalam Instalasi Farmasi Rawat Jalan RSUD Soehadi Prijonegoro Sragen. Metode penelitian ini adalah penelitian studi kasus dengan pendekatan kualitatif. Penelitian ini dilakukan di RSUD Soehadi Prijonegoro Sragen pada bulan Juni-juli 2022 dengan tahapan penelitian yaitu observasi dibuat dalam bentuk VSM, penyebaran kuisioner value pasien dan waste, melakukan wawancara dengan metode 5 why untuk mengetahui akar penyebab dan waste kritis, serta usulan perbaikan. Hasil penelitian menunjukan waste defect 21,1%. Transportation 18,1%, overproduction 16,3%,. Akar penyebab dari waste defect adalah kurang fokusnya petugas dan kurangnya sumber daya manusia, waste transportation adalah kekosongan obat dan tata letak yang kurang rapi, waste waiting adalah pasien harus mengantri di kasir dan pengambilan obat. Usulan perbaikan waste defect adalah penambahan SDM, waste transportation adalah mengatur tata letak rak obat yang lebih rapi, waste overproduction adalah tidak membuat racikan sebelum resep masuk.
PENGEMBANGAN SKRINING RESEP DARI HASIL EVALUASI SISTEM INFORMASI MANAJEMEN PELAYANAN RESEP DENGAN METODE HOT-FIT DI RSAU DR. EFRAM HARSANA Yasa, Gede Trima; P, Jason Merari; Rahmawati, Ismi
Jurnal Kesehatan - STIKes Prima Nusantara Vol 13 No 3 (2022): Jurnal Kesehatan
Publisher : LPPM Universitas Prima Nusantara Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35730/jk.v13i3.728

Abstract

Latar Belakang: Evaluasi sistem informasi manajemen merupakan suatu usaha nyata untuk mengetahui seberapa baik sistem tersebut telah diterapkan pada sebuah organisasi. Evaluasi sistem informasi manajemen skrining perlu dilakukan mengingat sistem skrining resep yang terdapat di RSAU dr. Efram Harsana masih dilakukan dengan cara manual.Tujuan: Penelitian ini bertujuan untuk mengevaluasi dan mengembangkan sistem informasi manajemen skrining resep di RSAU dr. Efram Harsana.Metode: Penelitian ini menggunakan rancangan deskriptif kuantitatif dan kualitatif dengan metode HOT-Fit di mana variabel bebas yang terdiri dari Human, Organization dan Technology, sedangkan variabel tergantung Net-benefit.  Evaluasi SIM meliputi penyebaran kuesioner, wawancara kepada responden pengguna dan pengelola SIMFRS. Pengembangan SIM skrining resep dilakukan dengan bantuan diagram DFD dan ERD. Uji T-Paired dengan aplikasi SPSS versi 24 dilakukan untuk membandingkan perbedaan sebelum dan sesudah penerapan pengembangan sistem informasi manajemen skrining resep.Hasil: Hasil dari evaluasi yang telah dilakukan, secara umum sistem informasi manajemen farmasi rumah sakit di RSAU dr. Efram Harsana sudah berjalan dengan baik, dilihat dari persentase responden yang memberikan pendapat setuju dengan skor 3 terhadap faktor yang mempengaruhi berjalannya SIM..Kesimpulan: Hasil pengembangan SIM skrining resep dapat diterima dengan baik, ini dilihat dari hasil uji T-paired pada aspek Human, Organization, Technology dan Net-benefit dengan tingkat signifikansi yaitu 0,001; 0,000; 0,001; 0,008 dan persentase peningkatan secara berturut-turut sebesar 13,85; 20,70; 20,24 dan 15,34%.
ANALISIS PENERAPAN SISTEM INFORMASI DALAM MENDUKUNG PENGELOLAAN OBAT DI INSTALASI FARMASI RSU RAJAWALI CITRA BANTUL MENGGUNAKAN MODEL TASK TECHNOLOGY FIT Ricky Romadhon; Jason Merari Peranginangin; Jamilah Sarimanah
Jurnal Permata Indonesia Vol 17 No 1 (2026): Volume 17 Nomor 1, Mei 2026
Publisher : Politeknik Kesehatan Permata Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59737/jpi.v17i1.396

Abstract

Sistem Informasi Farmasi (SIF) merupakan komponen integral dari Sistem Informasi Manajemen Rumah Sakit yang berfungsi mendukung pengelolaan obat secara terintegrasi dan efisien. Namun dalam praktiknya, masih ditemukan sejumlah kendala, di antaranya ketidaksesuaian fitur sistem dengan kebutuhan tugas, kesalahan perhitungan stok saat beban akses tinggi, serta downtime jaringan yang menghambat validasi resep secara real-time. Penelitian ini bertujuan menganalisis sistem informasi farmasi dalam mendukung pengelolaan obat di Instalasi Farmasi RSU Rajawali Citra Bantul menggunakan model Task-Technology Fit (TTF). Pendekatan kualitatif deskriptif diterapkan melalui wawancara mendalam, observasi lapangan, dan studi dokumentasi terhadap tenaga farmasi yang secara langsung menggunakan sistem informasi. Data dianalisis menggunakan metode Open Coding untuk mengidentifikasi karakteristik tugas, karakteristik teknologi, kesesuaian tugas-teknologi, tingkat pemanfaatan sistem, dan dampak kinerja. Hasil penelitian menunjukkan bahwa SIF telah digunakan untuk mendukung berbagai kegiatan pengelolaan obat mulai dari perencanaan hingga pelaporan, serta mampu meningkatkan efisiensi kerja, kecepatan pelayanan, dan ketepatan pengelolaan data. Kesesuaian antara tugas dan teknologi belum optimal karena masih terdapat proses manual, keterbatasan fitur, serta kendala teknis berupa error sistem, downtime, dan ketidakstabilan jaringan. Pemanfaatan sistem memberikan dampak positif terhadap kinerja tenaga farmasi, namun belum maksimal akibat adanya double entry sistem, keterbatasan sumber daya manusia, dan infrastruktur yang belum sepenuhnya mendukung. Pengembangan sistem yang lebih terintegrasi, peningkatan stabilitas, dan penguatan sumber daya manusia diperlukan agar SIF dapat mendukung pengelolaan obat secara lebih optimal dan berkelanjutan.
The Potential Of Superoxide Dismutase Enzyme From Tomato Fruit (Solanum Lycopersicum) To Repair Collagen Damage In 3t3 Fibroblast Cells Exposed To Ultraviolet A Radiation Rosliana Patandung; Ana Indrayati; Jason Merari P
Eduvest - Journal of Universal Studies Vol. 4 No. 6 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i6.1471

Abstract

UV A radiation can cause photoaging to the skin which is show by a decrease in the amount of collagen and death of fibroblast cell. This study aimed to determine the SOD enzyme activity of tomatoes (Solanum lycopersycum Mill.) influences the increase of viability of fibroblast cell and deposition of collagen. The study design used a completely randomized design (CRD) with 11 treatments and 3 repetitions. The procedures of this study include: (1) extracting SOD enzymes (2) making bradford reagents (3) making standard protein solutions (4) measuring total protein content (5) testing the antioxidant activity of SOD enzymes (6) preparing 3T3 fibroblast cells (7) Cell exposure 3T3 fibroblasts with UV A rays (8) preparation of tomato SOD enzyme stock solutions (9) determination of cell viability and collagen deposition. Data analized by normality test, homogeneity test, one way ANOVA test, tuckey test and dunnet test. The results of SOD enzyme activity showed the highest percent inhibition was 77.83%. Highest value of percent viability of fibroblast cells that were exposed to UV A rays after given 90% SOD enzyme treatment was 233.00% and collagen deposition was 157.67%. The results showed that variations in the SOD enzyme concentration of tomatoes had a significant effect on cell viability and collagen deposition in fibroblast cells. with a value of sig = 0,000 (p <α). Based on the result, we can concluded that SOD enzyme from tomatoe fruit show significant activity as anti-photoaging.
Gastroprotective Activity of Inhaled Curcuma Rhizome Essential Oil on Male Mice Induced by Acute Stress Jeni Mistya Intan Awani; Jason Merari Peranginangin; Tri Wijayanti
Indonesian Journal of Global Health Research Vol. 8 No. 1 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i1.375

Abstract

Stress is the body's response to physical, emotional, or psychological stress. One of the causes of stress is sound. This study aims to determine the gastroprotective activity of the stomach of male mice given inhalation of curcuma rhizome essential oil and induced acute stress using an ultrasonic modification method. The study was conducted experimentally using male mice divided into 6 groups, namely group 1 as a normal control that was not induced by anything. Group 2 was induced by stress with ultrasonic, group 3 was a positive control given ranitidine 0.8 mg/20 grams of mouse body weight which was given orally and induced stress with ultrasonic. Group 4 was induced by stress and given inhalation of curcuma rhizome essential oil at a concentration of 0.5%, Group 5, was induced by stress and given inhalation of curcuma rhizome essential oil at a concentration of 1% and Group 6, was induced by stress and given inhalation of curcuma rhizome essential oil at a concentration of 2%. Stress was induced using an ultrasonic method, and the parameters measured were the pH of gastric fluid. The results of the study showed that inhalation of curcuma rhizome essential oil provided a gastroprotective effect, indicated by a decrease in the number of gastric ulcers and the severity of gastric ulcers.
Needs Analysis and Development of Pharmacy Management Information Systems Nurul Huda; Jason Merari Peranginangin; Tri Wijayanti
Indonesian Journal of Global Health Research Vol. 8 No. 3 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i3.1300

Abstract

Pharmacy management in Blora Regency, Central Java, is dominated by manual systems such as stock recording in ledgers, causing inventory errors, transaction delays, and the risk of expired drugs. With 300 pharmacies serving 1 million people in rural areas, the problem is exacerbated by limited digital infrastructure and real-time BPOM-JKN regulatory requirements, as well as the impact of the COVID-19 pandemic. As many as 65% of pharmacies in Central Java are not yet computerized, resulting in 15-25% of stock wastage. This study aims to: (1) analyze the needs of pharmacy management information systems (SIM); (2) design and develop SIM based on UML and the DeLone-McLean model; (3) compare the satisfaction of respondents with existing SIM versus new SIM. The quantitative positivism approach involved 22 pharmacists who own pharmacies in Blora (systematic sampling), a 1-5 Likert questionnaire, observation, a 7-day prototype test, and SPSS 25 analysis (validity, reliability, Kolmogorov-Smirnov, paired t-test/Wilcoxon). Feature priorities included purchase/return reports (77.3%) and user access (77.3%). The post-test showed significant improvements: system quality (31.8%→86.4%), information (36.4%→81.8%), service (45.5%→86.4%), usage (50%→90%), satisfaction (45.5%→86.4%); temporary benefits decreased (45.4%→31.8%). The new SIM increases efficiency by 40-50%, accuracy by 95%, saves 50% of time, and supports compliance with Minister of Health Regulation No. 73/2016. Recommendations include training for the Health Office, BPJS integration, and AI stock prediction for rural replication.
Activity Test of Matoa Leaves on Angiotensin II as an Increasing SOD and GPx Octaviana Dyah Oentari; Jason Merari Peranginangin; Ika Purwidyaningrum
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 3 No 2: November 2024
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0302.752

Abstract

The leaves of the matoa are plants that can be used for hypertension. Matoa leaves were assume to have thought to have hypertensive activity because they contain flavonoids (quercetin-3-O-rhamnosida). Flavonoids can lower blood pressure which is modulated by the Renin-Angiotensin-Aldosterone System (SRAA). Was to fine out about the giving process of matoa leaf extract and fractions in increasing levels of SOD and GPx. This research used the maceration method with 96% ethanol solvent and fractionated by liquid-liquid method using n-hexane fraction solvent, ethyl acetate fraction, and water fraction. In this study, 21 male white rats with Wistar strain were divided into 7 groups, group I named as normal control, group II as negative control (CMC-Na 1%), group III as positive control (Irbesartan), and Group IV. (matoa leaf extract), Group V (n-hexane fraction group VI (ethyl acetate fraction) group VII (water fraction). The data obtained were analyzed with the Shapiro Wilk test, Levene's test and ANOVA. The results showed that the matoa leaf extract a dose 300mg/kg BB lower blood pressure in angiotensin II induced rats incrase SOD and GPx levels in the liver induced by Angiotensin II.
Co-Authors Ahmad Nuzulul Abid Aminudin Ana Indrayati Andre Kurniawan Antoro, Sutopo Edy arikha ayu susilowati Aryani, Norsarida Astuty, Meilinda Windy Atalia Tamo Ina Bulu Boedirahardja, Partana Chairun Darmawan, Nopandi Wisnu Desi Alviona Dewi Ekowati Dewi, Lucia Vita Inandha Dewi, Lucia VIta Inandha Dewi, Lutfiana Aswindra Diah Kartika Putri Dian Marlina Dwiannur, Febriandi Ramadhan Endang Diyah Ikasari Felix Imanuel Rachman Fitriarahmah, Giyan Gede Trima Yasa Gede Trima Yasa Gunawan Pamudji Widodo Harsono, Samuel Budi Ika Purwidyaningrum Ilham Kuncahyo Ismi Rahmawati Isna Jati Asiya Iswandi -, Iswandi Iswandi Iswandi Iyem Shahira Jamilah Sarimanah Jeni Mistya Intan Awani Julia Megawati Djamal Keswara, Yane Dila Krisdita Sundari Putri Prayitno Lutfi Nofitasari Magdalena Retnoningsih Mardiyono Marlina, Dian Melviani Mohammad Fauzy R. Syahruddin Muhamad Aulia Putra Tawakal Muhimmatul Khoiriyah Munawarah Munawarah Muslihatin, Muslihatin Mustika Endah Pratiwi Najmah Salsabila Nia Azzahra Nofika Dwi Anitasari Novitarini Nur Anggreini Dwi Sasangka Nurul Huda Octaviana Dyah Oentari Onny Ziasti Fricilia Opstaria saptarini Prasojo Pribadi Pudiastuti RSP R.F.X Premihadi Putra Rahmawati, Ismi Reslely Harjanti Ricky Romadhon Riskayanti Rizal Maarif Rukmana, Rizal Maarif Rosliana Patandung Sabda Wahab Sarimanah, Jamilah Sawal, Rizky Ardian Hartanto Sholehah, Faza Putri Farihatus Sisca Latue Sofia, Anna Sri Rejeki Handayani Sudarwati, Vivid Latri Suhailah, Dhia Sulaiman, Teuku Nanda Saifullah Susanti, Kharisma Dewi Fadia Syamsul Ma'arif Titik Sunarni Titik Sunarni Tri Murti Andayani Tri Wijayanti Tri Wijayanti Widhoretno Puspandari Windi Antika Wiratantri, Fitra Indah Wiwin Herdwiani Wiwin Herdwiani Yasa, Gede Trima Yaya Sulthon Aziz