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Edukasi Skrining COVID-19 pada Program Teknologi Reproduksi Berbantu di Era Pandemi COVID-19 Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; Darto, Darto; Ratnasari, Affi Angelia; Anggraeni, Asih
Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Vol 5, No 2 (2023): Juli-Desember
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/baktiku.v5i2.7064

Abstract

In the era of the coronavirus disease 2019 (COVID-19) pandemic, COVID-19 screening education is essential for the general public, especially for those who undergo assisted reproductive technology (ART) programs. Understanding the preventive measures and precautions of COVID-19 during the treatment process is necessary. Health care staff must also understand the importance of proper COVID-19 screening and control measures. This educational activity is in the form of a YouTube live streaming program that can be followed by the general public, including infertile couples who want to know about infertility, examination procedures, COVID-19 screening guidelines, and the TRB program. Education about COVID-19 screening can minimize stigma and enhance public confidence in the screening procedures. The results of this educational delivery make the general public, especially couples who will undergo the ART program, ready and have the ability to undergo COVID-19 testing, services, and screening. In addition, by providing education and implementing effective screening, we can work together to combat the COVID-19 pandemic and ensure that people receive quality and safe health services.
Kolaborasi Tenaga Medis dan Masyarakat dalam Mendukung Layanan Infertilitas Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; ., Darto; Ratnasari, Affi Angelia; Anggraeni, Asih; Wijayanti, Agung Sari
Jurnal Abdidas Vol. 5 No. 6 (2024): Desember
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v5i6.1066

Abstract

Kolaborasi antara tenaga medis dan masyarakat memiliki peran penting dalam mendukung penanganan infertilitas, sebuah kondisi yang sering menyebabkan kecemasan, stres, dan dampak negatif lainnya pada kesehatan mental. Tenaga medis berperan dalam diagnosis, perencanaan pengobatan, dan mendukung pasien mencapai tujuan mereka untuk memiliki anak, sementara masyarakat dapat memberikan dukungan emosional yang membantu mengurangi isolasi dan depresi pasien. Kegiatan pengabdian ini berfokus pada edukasi dan pemberdayaan tenaga medis serta masyarakat untuk meningkatkan pemahaman dan kapasitas mereka dalam mendukung individu dengan infertilitas. Evaluasi menggunakan pre-test dan post-test menunjukkan bahwa 25% peserta mengalami peningkatan pengetahuan setelah kegiatan, sementara 72% telah memiliki pemahaman yang memadai sebelumnya. Hasil ini menggambarkan efektivitas program dalam meningkatkan pemahaman terkait infertilitas. Selain itu, kegiatan ini berhasil menyebarkan informasi akurat dan memerangi mitos yang beredar di komunitas, sehingga meningkatkan kesadaran dan mengurangi stigma terhadap individu dengan infertilitas. Kesimpulannya, program ini efektif dalam meningkatkan dukungan sosial dan kapasitas tenaga medis untuk memberikan perawatan holistik yang lebih baik bagi pasien infertilitas, serta berkontribusi pada pengurangan dampak psikologis dan sosial yang dialami pasien.
Unraveling Of Urinary Disorders to Adenomyosis and Dysmenorrhea darto, darto; Anggraeni, Asih; Ngudi Insan Ksyatria, Yudhistira; Alifa, Rosita; Farras Wahdan, Arib; Retno Budihastuti, Uki; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; Angelia Ratnasari, Affi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 1 January 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i1.2203

Abstract

Objective : This study aims to explore the relationship between micturition disorders and adenomyosis and dysmenorrhea and provide insight into the factors associated with the severity of LUTS symptoms in these conditions. Methods : This study was a descriptive qualitative study. We retrospectively collected medical record data from the Obstetrics Gynecology Outpatient Ward of Dr. Moewardi Surakarta General Hospital in the period January 2021 to May 2023. The results of this study analyzed using Pearson correlation analysis if normally distributed and using Mann-Whitney if not normally distributed, thus, statistically analyzed. Results: There is a significant relationship between adenomyosis and dysmenorrhea on urinary disorders (p value of 0.016) where urinary disorders are found to be more severe in adenomyosis patients with dysmenorrhea. Conclusion : Lower urinary tract symptoms are common in symptomatic adenomyosis patients and greatly affect the patient's quality of life. Dysmenorrhea can be a potential risk factor that increases the occurrence of moderate to severe LUTS. Keywords: adenomyosis; dysmenorrhea; urinary disturbance.
Hyaluronic Acid for Sperm Selection in Patients Undergoing IVF with Teratozoospermia : a Bibliographic Analysis Zacky Arda, Mohammad; Melinawati, Eriana; Pertiwi, Kartika
GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Vol. 4 No. 4 (2025): GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh - Agustus 20
Publisher : Program Studi Kedokteran Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jkkmm.v4i4.23902

Abstract

Sperm selection technique and Assisted Reproductive Technology (ART) often overlook patients with teratozoospermia, who are more likely to have Deoxyribonucleic Acid (DNA) fragmentation in their sperm, leading to reduced fertilization rates, poor embryo quality, and lower implantation rates during In Vitro Fertilization (IVF). Hyaluronic Acid (HA) binding sperm offers enhanced outcome in ART. This study aimed to obtain information from global scientific research related to HA and sperm selection during In Vitro Fertlization (IVF) procedure by identifying key research trends, influential studies, and emerging themes through bibliometric analysis. The Scopus database was employed to search articles published with keywords “HA,” “teratozoospermia,” and “IVF.” VOSviewer was used to visually represent the bibliometric data, revealing trends in research related to HA for IVF procedure in patients with teratozoospermia. There were 150 articles identified, of which terms like “fragmentation”, “teratozoospermia”, and “sperm abnormalities” are the highlight emerging topics to understand male infertility. Through the years, newer methodologies and techniques in sperm analysis and fertility treatments research had evolved, while research in HA and IVF had increased significantly in many publications and institutions. In conclusion, this bibliometric mapping study has identified key themes and emerging trends, including the critical roles of sperm morphology, motility, and selection in IVF. The growing interest in the relationship between HA and sperm selection techniques highlights the need for ongoing research into HA's application in sperm selection, particularly regarding DNA fragmentation and its effects on fertilization and embryo quality to improve reproductive outcomes.
Edukasi Menopause Sehat bersama Ikatan Istri Dokter Indonesia (IIDI) Menuju Kehidupan Berkualitas Budihastuti, Uki Retno; Melinawati, Eriana; Laqif, Abdurahman; Anggraeni, Asih; Ratnasari, Affi Angelia
Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Vol 7, No 1 (2025): Januari-Juni
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/baktiku.v7i1.13032

Abstract

Menopause is a natural phase that every woman must experience, but it is often accompanied by various physical and emotional complaints that can interfere with daily life and reduce the quality of life. The lack of understanding and access to information makes most women unprepared to face this phase. The purpose of community service activities is to increase the knowledge and awareness of women aged 40 years or older about the concept of healthy menopause. The activity was carried out in a hybrid manner at the Auditorium of the Faculty of Medicine, Sebelas Maret University, involving obstetrics and gynecology specialists, health workers, and members of the IIDI Solo Branch. The implementation method includes counseling, interactive discussions, and evaluation through a pretest and a posttest. The results of the activity showed an increase in the average knowledge score of participants from 82.43 to 85.59, accompanied by an increase in awareness of the importance of early detection and handling of menopausal complaints. These findings confirm that sustainable education is an effective strategy to improve the quality of life of women in the lead-up to old age, in line with the goals of SDG 3, which emphasizes the importance of ensuring healthy lives and well-being for all ages.
Peningkatan Kesadaran dan Deteksi Dini Kanker Serviks dan Kanker Payudara melalui Edukasi dan Skrining bagi Tenaga Kesehatan dan Masyarakat Budihastuti, Uki Retno; Melinawati, Eriana; Priyanto, Heru; Ratnasari, Affi Angelia; Susilawati, Tri Nugraha; Prastyoningsih, Aris; Septiana, Yesika Cahya; Mufidah, Amatullah
Jurnal Abdidas Vol. 6 No. 4 (2025): Agustus 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v6i4.1171

Abstract

Kanker serviks dan kanker payudara merupakan dua jenis kanker yang paling umum menyerang wanita di seluruh dunia. Kanker serviks disebabkan oleh infeksi human papillomavirus (HPV), sedangkan kanker payudara disebabkan oleh pertumbuhan sel abnormal pada jaringan payudara. Deteksi dini dan pengobatan yang tepat dapat meningkatkan kemungkinan kesembuhan dan mengurangi angka kematian. Oleh karena itu, edukasi dan deteksi dini kanker serviks dan kanker payudara sangat penting untuk meningkatkan kesadaran dan kesehatan masyarakat. Dalam pengabdian masyarakat ini, kami melakukan edukasi dan deteksi dini kanker serviks dan kanker payudara pada tenaga kesehatan dan masyarakat wanita yang berdomisili di area Solo Raya. Hasilnya menunjukkan bahwa edukasi dan deteksi dini dapat mengingatkan kembali kesadaran dan pengetahuan masyarakat tentang kanker serviks dan kanker payudara, serta meningkatkan kemungkinan deteksi dini dan pengobatan yang tepat.
Testosterone Levels And Dna Fragmentation Index In Male Undergoing Intrauterine Insemination After Vitamin D3 Supplementation Wijayanti, Agung Sari; Budihastuti, Uki Retno; Melinawati, Eriana; Laqif, Abdurahman; Fahsan, Fatmiyanti
Indonesian Basic and Experimental Health Sciences Vol. 13 No. 1 (2024): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol13iss1pp16-22

Abstract

Nutrition is one of the factors that contribute to male infertility. Vitamin D3 are known to affect spermatozoa and usually served in fertility supplementation in doses of 400 and 1000 IU. Low levels of vitamin D3 have been linked to decreased sperm quality and quantity. This research would like to know the effect of Vitamin D3 to the DNA Fragmentation Index (DFI) and Testosterone blood level in men undergoing intrauterine insemination (IUI). This was an analytical observational study with two groups and a pretest-posttest design. Seventeen men aged 20 to 45 who were undergoing the IUI program and did not have diabetes or hypertension are participate in this study. Sperm DFI was determined by using an ELISA method with a DNA Kit. Blood testosterone levels in ng/mL units was measure using ELISA. IBM-SPSS version 22 was used to perform univariate and bivariate analysis on the collected data. The blood level of Vitamin D3 was significantly increased after the intervention of six week Vitamin D3. Meanwhile, this study shows there are no differences in the level of blood testosterone before and after treatment. The DFI was significantly increased in the 400 IU groups.
Mosaic Form of Turner Syndrome Laqif, Abdurahman; Wijayanti, Agung Sari; Moelyo, Annang Giri; Budihastuti, Uki Retno; Melinawati, Eriana
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 1 January 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i1.1826

Abstract

Objective: To report a case of breast growth disorder in a mosaic form of Turner Syndrome. Turner syndrome is a chromosomal condition characterized by small height and primary ovarian insufficiency that affects one in every 2500 female births. Mosaicism is likely to occur when monosomy X develops in only a few cells during development. The clinical presentation of Turner syndrome mosaicism is atypical, with symptom severity varying based on the number of affected cells. This case discusses issues with secondary sex development, including mild hyperandrogenism, and explores how combination hormonal treatment can aid in enhancing secondary sex development. Method: Case Report. Case: A 21-year-old woman presented with chief complaint of the lack of breast enlargement. She exhibited normal genitalia internally and externally and had a regular menstrual cycle. Karyotyping revealed a mosaic pattern of 45, X/46, XX (1 percent/99%) with normal estradiol levels and elevated testosterone levels (indicating mild hyperandrogenism). The patient underwent two cycles of hormone therapy using Ethinyl Estradiol and Drospirenone, resulting in breast growth progression from Tanner stage 1 to Tanner stage 2. Conclusion: Mosaicism in Turner syndrome is plausible, and the severity of clinical symptoms correlates with the number of defective chromosomes. The presentation of Turner syndrome mosaicism varies, and therapy should be tailored to address specific symptoms. While breast development is observed in some girls with Turner Syndrome, instances of breast growth disorder may occur, involving estrogen activity and estrogen receptor sensitivity. Although the exact cause of impaired breast growth remains unknown, administering estrogen in such cases can improve secondary sexual characteristics. Keywords: mild hyperandrogenism, mosaicism, turner syndrome
Rontgen Toraks, Nilai Cycle Threshold dan Hubungannya dengan Tingkat Keparahan Klinis pada Ibu Hamil dengan COVID-19 di RSUD Dr. Moewardi Regita, Immanuela Maria; Melinawati, Eriana; Prabowo, Wisnu; Budihastuti, Uki Retno
Plexus Medical Journal Vol. 2 No. 6 (2023): Desember
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v2i6.634

Abstract

Pendahuluan: Penggunaan pemeriksaan penunjang dalam mendiagnosis COVID-19 pada ibu hamil merupakan sebuah tantangan karena perubahan fisiologis yang unik pada ibu hamil menyebabkan variasi hasil. Kerentanan ibu terhadap patogen mungkin dapat berisiko menjadi perkembangan ke arah penyakit yang lebih parah. Namun terdapat kesimpangsiuran data pada hubungan pemeriksaan laboratorium seperti radiologi dan RT-PCR terhadap keparahan klinis ibu hamil. Oleh karena itu, penelitian ini bertujuan untuk mempelajari nilai CT, gambaran rontgen toraks dan hubungannya dengan tingkat keparahan klinis pasien ibu hamil dengan COVID-19. Metode: Data diperoleh dari rekam medis di rumah sakit tingkat tersier di Surakarta, Indonesia. Ibu hamil yang menjalani tes RT-PCR dan foto rontgen dada selama rawat inap pada periode Januari sampai Desember 2021 diperiksa. Nilai CT dari hasil RT-PCR positif dimasukkan dalam data penelitian. Keparahan ibu hamil berdasarkan presentasi klinis dibagi menjadi tiga kelompok: ringan, sedang dan berat. Data yang diperoleh kemudian dianalisis. Hasil: Terdapat enam puluh tujuh data ibu hamil pada penelitian ini. Rerata usia kehamilan saat admisi adalah 38 minggu. Karakteristik seperti usia, usia kehamilan, komorbid tidak mempengaruhi keparahan klinis. Nilai CT gen ORF1ab dan gen E tidak berhubungan dengan tingkat keparahan klinis. Namun korelasi signifikan ditemukan antara gambaran rontgen dada dan keparahan klinis penyakit (p=0.000, r=0.486). Kesimpulan: Tidak ada hubungan yang signifikan secara statistik antara nilai CT dan tingkat keparahan klinis ibu hamil. Namun, terdapat hubungan signifikan secara statistik antara rontgen toraks dan tingkat keparahan klinis ibu hamil.
Sexual Function Disorders after Hormonal Therapy or Surgery for Endometriosis in Moewardi General Hospital, Surakarta Anggraeni, Asih; Budihastuti, Uki Retno; Darto, Darto; Laqif, Abdurrahman; Melinawati, Eriana; Ksatriya, Yudhistya Ngudi Insan; Wijayanti, Agung Sari; Nuur, Aliffudin
Jurnal Kedokteran Brawijaya Vol. 34 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Endometriosis significantly affects women’s sexual health, manifesting as pain and dyspareunia, which reduces quality of life. In Indonesia, hormonal and surgical interventions are both used to manage endometriosis. However, the study of their effect on sexual function among Indonesia’s population is still unclear. This quasi-experimental study included 60 women, divided into two groups based on the type of therapy. This study was conducted from June to September 2024 at the Department of Obstetrics and Gynecology, Dr. Moewardi General Hospital. Outcomes were assessed with the Female Sexual Function Index (FSFI) questionnaire, before and after treatment. The analysis showed the mean rank of the surgical intervention (44.97) is higher than the hormonal intervention (16.03). The Mann-Whitney U test revealed a significant difference between the two groups of intervention (p=0.000). These findings indicate that surgical intervention is superior to hormonal therapy in improving the FSFI score that reflects sexual function among women.  
Co-Authors ., Darto Abd. Rasyid Syamsuri Abdurahman Laqif Abdurahman Laqif Abida Zuhra Jatiningtyas Agung Sari Wijayanti Alfi Marita Tristiarti Alfi Marita Tristiarti Alfi Marita Tristiarti Alifa, Rosita Amira Masiah Syahvira Andreas Peter Sitorus Andreas Peter Sitorus Angelia Ratnasari, Affi Anggraeni, Asih Annang Giri Moelyo Asih Anggraeni Besar, Dwi Sakti Berlian Cahyono Hadi Darto Darto Darto - Darto - Darto . Darto . Darto Darto Dewi Kartika DJ Anwar Dwi Septiadi Badri Dyah Ratna Budiani Ediningtyas, Atifa Nadira Elita Rahmi Eric Edwin Yuliantara Fahsan, Fatmiyanti Farras Wahdan, Arib Hadi, Cahyono Hafiizha, Attahira Amalia Hanifah Karim Hapsari Nur Primastuti Hapsari Nur Primastuti Hermawan Udiyanto Heru Priyanto Heru Priyanto Ida Nurwati Jatiningtyas, Abida Zuhra Kartika Pertiwi Ksatriya, Yudhistya Ngudi Insan Laqif, Abdurahman Laqif, Abdurrahman Lukman Aryoseto Lukman Aryoseto Lunardhi Susanto Marbun, Yohan Pamuji Mashuri, Yusuf Ari Metanolia Sukmawati Mufidah, Amatullah Mulyoto Pangestu Ngudi Insan Ksyatria, Yudhistira Nutria Widya Purna Anggraini Nuur, Aliffudin Octavia, Dhamayanti Eka Prastyoningsih, Aris Prisasanti, Dympna Prameilita Raden Rara Pandhan Budi Larasati Rakano Kautsar Dwiyana Rantasari, Affi Angelia Ratnasari, Affi Angelia Regita, Immanuela Maria Saputra, Ricky Bernadi Sari, Arum Dessy Rahma Septiana, Yesika Cahya Sri Sulistyowati Sri Sulistyowati Supriyadi Hari Respati Supriyadi Hari Respati Tanti Arianti Teguh Prakosa, Teguh Tri Nugraha Susilawati Uki Retno Budihastuti Vicky Eko N.H Vicky Eko N.H Wasyanto, Trisulo Wesliaprilius, Todung Antony Wijayanti, Agung Sari WISNU PRABOWO Yulyanti, Yulyanti Zacky Arda, Mohammad