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All Journal Jurnal Kedokteran Brawijaya e-Journal Pustaka Kesehatan EQUILIBRIUM Majalah Kedokteran Gigi Indonesia Journal of Agromedicine and Medical Sciences UNEJ e-Proceeding Jurnal Ilmiah Kedokteran Wijaya Kusuma Health Notions Multidiciplinary Journal Medical Technology and Public Health Journal Jurnal Mekanova : Mekanikal, Inovasi dan Teknologi Jurnal MID-Z (Midwivery Zigot) Jurnal Ilmiah Kebidanan Indonesian Journal of electronics, electromedical engineering, and medical informatics Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Journal of Telenursing (JOTING) Jurnal Surya Muda: Ilmu Keperawatan dan Ilmu Kesehatan AloHA International Journal of Health Advancement (AIJHA) GANESHA MEDICINA Hang Tuah Medical Journal Jurnal Pengabdian Pada Masyarakat Journal for Quality in Public Health Jurnal Manajemen dan Pendidikan Agama Islam Neurona
Al Munawir
Department Of Pathology, Faculty Of Medicine, University Of Jember, Jember, 68121 Indonesia
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Pengaruh Pemberian Gel Doksisiklin terhadap Jumlah Makrofag pada Proses Penyembuhan Dermatitis Paederus akibat Racun Tomcat (Paederus sp.) pada Mencit (The Effect of Doxycycline Gel Application toward the Number of Macrophage in Dermatitis Paederus He Bagus Indra Kusuma; Al Munawir; Septa Surya Wahyudi
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Paederus dermatitis is an acute skin irritation caused by skin contact with toxins in the rove beetle (Paederus sp). Pederin poison was previously thought derived from the rove beetle's body. Based on other studies, poison pederin obtain from the symbiotic rove beetles and Pseudomonas aeruginosa which is able to secrete the matrix metalloprotease (MMP). Doxycycline is an antibiotic act as an inhibitor of MMP. This study aimed to verify the effect of Doxycycline gel to the number of macrophages in healing process Paederus dermatitis due to poison of rove beetle (Paederus sp.). The study design was a quasy experimental design using 40 mice (Mus musculus), were divided into 4 groups. Normal control group, negative control group, P1 group was given doxycycline 1%, and P2 group was given doxycycline 5%. Experimental animals were terminated on day 1, 3, 5, 7, and 15. The result of One Way Annova test on the number of macrophages on day 1, 3 and 5 showed a significance of 0.00 (p<0.05). This study showed that there was a significant difference in the effect of doxycycline gel to the number of macrophages in healing process of Paederus dermatitis. Keywords: dermatitis paederus, doxycycline gel, macrophages
EFFECT OF POMELO (CITRUS GRANDIS) ETHANOLIC EXTRACT ON ATHEROSCLEROTIC PLAQUE FORMATION Mudzakkir Taufiqurrahman; Kiky Martha Ariesaka; Hilda Khairinnisa; Wahyu Dian Puspita; Azka Darajat; Al Munawir
UNEJ e-Proceeding 2016: Proceeding The 1st International Basic Science Conference
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Cardiovascular disease is a major health problem in developed and developing countries and still be the first rank causing death in the world, including Indonesia. Most of cardiovascular disease caused by atherosclerosis. Macrophage apoptosis can reduce the size of atherogenic lesions and the progression of atherosclerotic plaque formation. Proapopstosis effects on macrophages owned by flavonoids. This study aims to know the potential of flavonoids found in Citrus grandis extract which works by suppressing the phosphorylation of AKT Ser473 so that the formation of foam cells (foam call) can be minimized. The research sample is 38 male Wistar rats weighing 90-150 grams. Samples were divided into 5 groups. All groups except normal control group were induced atherosclerosis by utilizing the shear stress mechanism at the branch of the abdominal aorta. Shear stress created by injecting adrenaline i.v. followed by hyperlipidemic diet (egg yolk) for 3 weeks. Then, during the next two weeks, the positive control group treated with simvastatin, while the treatment group were treated with extracts of C. grandis (ECG) known to contains flavonoids. Macroscopic showed that ECG could reduce atherosclerotic lesions. of citrus grandis. The sample data captured in the form of mouse blood and abdominal aortic tissues. Based on the results of the TLC screening, Ethanolic Extrxct Meanwhile, the group given simvastatin as a positive control also showed fewer atherosclerotic lesions. ECG proven to lower cholesterol and triglyceride levels of rats that had been induced atherosclerosis. Award ECG doses of 500 and 1000 mg/kg showed a significant decrease in cholesterol (p <0.01) compared to the negative control group. ECG is proven to reduce atherosclerotic lesions, so that ECG can be used as an adjuvant for simvastatin to achieve maximal therapeutic effect against atherosclerosis.
Potential of Cocoa Extract (Theobroma cacao) in Inhibiting Erythrocyte Damage Induced by Physalia utriculus Venom Adinningtyas Intansari; Al Munawir; Laksmi Indreswari
Journal of Agromedicine and Medical Sciences Vol 6 No 3 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i3.9661

Abstract

Physalia utriculus is one of the invertebrate marine biota that is often found in Indonesia. Some symptoms of venoming due to jellyfish stings cause pain, itching, and hemolysis. In Indonesia, 13 cases of jellyfish stings were reported in 2005-2009 with three people dying in Java, Bali, and Bangka. Cocoa beans (Theobroma cacao L.) contain fat, carbohydrates, proteins, and polyphenol compounds that are useful as antioxidants. Polyphenols in the form of epicathechins, catechins, and procyanidins serve to provide protection to hemolysis. The purpose of this study was to determine the potential of ethanol extract of cacao (Theobroma cacao L.) in inhibiting the damage of erythrocyte induced by Physalia utriculus in vitro. This study used 28 samples of erythrocytes divided into seven groups, namely the normal control group, negative controls, and treatment with cocoa ethanol extract 0.2%, 0.1%, 0.04%, and 0.02%. Each subsequent group induced venom Physalia utriculus. The results showed that the average speed of erythrocyte lysis in the treatment group by giving cocoa ethanol extract 0.2%, 0.1%, 0.04%, and 0.02% respectively (seconds ± standard deviation) was 858,25 ± 94,44; 1.000,5 ± 159,93; 678,5 ± 19,71; and 1.006 ± 159,50. The mean speed of erythrocyte lysis in the negative control group was 1,025 ± 164.63 and the positive control group with the administration of N-Acetylcystein can last up to one hour after administration of venoms. Test for normality and homogeneity shows that data is normally distributed and homogeneous. One Way Annova analysis shows the significance value of p <0.05, then a post hoc analysis test was performed with the Bonferoni method to find out the differences in significance in each group. In this study it can be concluded that the administration of cocoa ethanol extract has no potential to inhibit erythrocyte damage that has been venomed by Physalia utriculus in vitro. Keywords: Physalia utriculus, cacao, erythrocyte damage
The Effect Of Folic On Different Dosage Level Against Retina Destruction Level Of Mice With Peroral Methanol 50% I Gusti Ngurah Agung Darma Putra; Al Munawir; Sugiyanta sugiyanta
Journal of Agromedicine and Medical Sciences Vol 3 No 2 (2017)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v3i2.5066

Abstract

In recent years, there are many methanol poisoned cases. Methanol poisoned cause of blindness, CNS problem, and metabolic acidosis. Folic acid is the one of many medicinal treatment for methanol poisoned. Folic acid has important role on methanol metabolism in our body. The aim of the study was to known the effect of addition folic acid on retina damage level of methanol poisoned. The method is experimental laboratories (true experiment design) with post test only control group design. The study included 5 separate test. The subject were mice which in 2 - 3 months age and had weight about 25 - 35 gr. There were 5 groups subject in the study. There were control group which given usual meals for mice and aquadest, negative control group which given methanol 7gr/ kgBW, treatment group 1,2, and 3 were given methanol 7gr/kgBW and folic acid 1 mg/kg BW, 3mg/kgBW, and 5 mg/kgBW. The treatment was given about 24 hours, then the eyes of the mice were taken to made blood smear. Damage of eyes were evaluated based score determined before. It can be concluded that addition folic acid can reduce retina damage level of metanol poisoned.
Potential of Cocoa Ethanol Extract Toward Nematocyst Tubul Firing Inhibition of Physalia Utriculus Toxin In Vitro Sarwendah Siswi Winasis; Al Munawir; Adelia Handoko
Journal of Agromedicine and Medical Sciences Vol 5 No 2 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i2.9623

Abstract

There was estimated 150 million envenomation cases due to jellyfish stings occur globally every year. 100 from 10,000 jellyfish species in the world known to be dangerous, one them is Physalia utriculus. The aim of this study was to determine the potential of cocoa (Theobroma cacao L.) ethanol extract toward nematocyst tubul firing inhibition of jellyfish (Physalia utriculus) toxin in vitro. The method was true experimental design with post test only control group design. The study divided into 8 groups: 1 normal control, 1 positive control, 1 negative control, and 5 treatments grups by giving cocoa ethanol extract with concentration 20%, 2%, 0.2%, 0.02%, 0.002%. The observation was made by calculating the percentage number of firing nematocysts. The result showed average percentage of firing nematocyst in the normal control group was 42.50 ± 3.18, positive control group was 37.97 ± 5.57, negative control group was 52.44 ± 2.98, and treatment group which given with cocoa ethanol extract 20%, 2%, 0.2%, 0.02%, 0.002% were 48.24 ± 5.37; 40.62 ± 7.10; 29.45 ± 5.39; 37.60 ± 9.78; 41.11 ± 3.92, respectively. The One Way Annova statistical results test show significance value 0.001 (p≤0.05). The conclusion of this study was the cocoa ethanol extract with concentration 0.2% has most potential to inhibit the jellyfish (P. utriculus) nematocyst tubule firing in vitro. Keywords: Physalia utriculus, cocoa, toxin, jellyfish
Efektivitas Bina Keluarga Lansia (BKL) terhadap Kualitas Hidup Lansia Desy Tariustanti; Zarah Puspitaningtyas; Al Munawir
Multidisciplinary Journal Vol 4 No 2 (2021): Desember 2021
Publisher : Pascasarjana Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/multijournal.v4i2.30492

Abstract

Elderly family development is a group of family activities including the elderly and the elderly themselves which aims to improve knowledge, attitudes and behavior or family skills in order to improve the quality of life. the lives of the elderly. Elderly Family Development is a forum for the elderly to live healthy, active, productive and independent lives through group activities. The CoE Aging Family Development Program integrates a number of cross-sectoral activities, especially by coordinating with relevant agencies representing the government. Improving the quality of life as the goal of implementing health control programs is influenced by several factors, including physical, psychological, social and environmental. This research is a descriptive study with a qualitative approach which was carried out in the Drupadi Elderly Family Development group in Mimbaan Village. Research informants are the main informants for the elderly and their families, who provide additional information, namely midwives, curative practitioners and health service providers. family development for the elderly. The main informant is the Head of the Population and Family Planning Agency. The results showed that the Elderly Family Development program had an effect on the quality of life of the elderly. This was obtained from the results of in-depth interviews with key informants, additional informants and key informants. According to the informant, the activities of the health service program are very diverse so that the elderly are very enthusiastic to participate with the total number of participants for each activity is 70%. The results of in-depth interviews show that BKL has succeeded in improving the quality of life of the elderly. This can be seen from the narratives of informants and the daily activities of the elderly who are increasingly productive.
Pengaruh Faktor Risiko Terjadinya Katarak Terhadap Katarak Senil Pada Petani di Wilayah Kerja Puskesmas Tempurejo Kabupaten Jember Agung Sudrajat; Al Munawir; Supangat Supangat
Multidisciplinary Journal Vol 4 No 2 (2021): Desember 2021
Publisher : Pascasarjana Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/multijournal.v4i2.30475

Abstract

Eye health is important in achieving the quality of human resources in order to improve the quality of human life in the context of realizing a healthy, productive, and physically and mentally prosperous Indonesian society. Cataract is a disorder of the eye in which the lens of the eye becomes cloudy due to hydration of the lens (addition of fluid), denaturation of lens proteins or occurs due to both. The purpose of this study was to analyse the effect of cataract risk factors on the occurrence of senile cataracts in farmers in the Tempurejo Community Health Center, Jember Regency. The type of research used is observational analytic with case control research design. The population in this study was cataract cases based on the sensory health record files at the Tempurejo Health Center and farmers living in the working area of the Tempurejo Health Center with a simple number of 98 farmers, with a case sample of 48 farmers and a control sample of 48 farmers. Determination of the research sample using purposive sampling technique. The results of the study on farmers showed that female farmers 2.8 times (95%C1 1,221-6,423), farmers with low education and knowledge 2.7 times (95%C1 1,163-6,552) and 2.7 times (95%C1 1,217-6,366), farmers with socioeconomic less than 3.2 times (95%C1 1.309-7.898). Farmers have a history of hypertension 1.9 times (95%C1 0.764-5.081), farmers with ex-smoker/smoker status 1.6 times (95%C1 0.740-3.805) farmers work outside >4 hours per day 2.8 times (95%C1 1.189-6.866). The conclusion of this study, there is an effect of gender on senile cataract, there is an effect of education level and level of knowledge on senile cataract, there is a socio-economic effect on senile cataract, there is no effect of a history of hypertension on senile cataract, there is no effect of smoking habits on senile cataract, and There is an effect of working outside the building on senile cataract. Women farmers are advised to reduce the intensity of exposure to ultraviolet light. In addition, farmers should prioritize the use of PPE when working.
Analisis Pelayanan Obstetri Neonatal Emergensi Dasar Berdasarkan Program QA di Puskesmas PONED X Kabupaten Bondowoso Asti Nuris; Al- Munawir; Dewi Rokhmah
Multidisciplinary Journal Vol 3 No 2 (2020): Desember 2020
Publisher : Pascasarjana Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (769.542 KB) | DOI: 10.19184/multijournal.v3i2.24048

Abstract

As health service provider, primary health care should provide qualified and satisfied service among patients. The PONED is government’s program to reduce the maternal mortality rate. On the other hand, QA is a program used to preserve the quality of primary health care. The aim of this study is to analyze basic emergency neonatal obstetric by using QA program. This is qualitative study, where there were four informants in this study, consist of key-, main-, and additional- informant. Furthermore, the data was collected by in-depth interview. This study found that the variable of input of QA has not fulfilled and supported the implementation of PONED. The variable of process has not performed in accordance with the procedure yet. On the other hand, the variable of output showed that the performance has not been optimal yet. Keyword: PONED, QA, Quality
Satisfaction of Pregnant Women Toward Integrated Antenatal Care Service in Senduro Health Center, Lumajang in Decreasing MMR and IMR Based on Pregnant Mother’s Characteristics Aini Hidayati; Al Munawir; Ancah Caesarina Novi Marchianti
Aloha International Journal of Health Advancement (AIJHA) Vol 3, No 2 (2020): February
Publisher : Alliance oh Health Activists (AloHA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/aijha30201

Abstract

Maternal Mortality Rate becomes a global issue because it is an important indicator in determining public health degree, so each country has responsibility to avoid maternal death. An effort in accelerating the decrease of MMR with pregnancy checkup program is well known as Integrated ANC service program. Integrated ANC service is a comprehensive and quality antenatal provided to all pregnant mothers temporally during pregnancy. This research was aimed to analyze the satisfaction level on pregnant mothers on Integration of ANC service decreasing MMR and IMR based on characteristic of pregnant mothers in Senduro Health Center of Lumajang Regency on 2019. Type of this research was descriptive analysis using quantitative approach. Questionnaire about satisfaction level of ANC service in Senduro Health Center of Lumajang Regency on September to October in 2019 was applied. It also took 670 populations of pregnant mothers coming to Senduro Health Center of Lumajang Regency. Samples were taken by using systematic random sampling. Samples taken were 109 respondents based on specified criteria. Data collection results were processed by employing Chi Square statistical test with a significant level of 0.05. The result of this research showed that most patients about 58 pregnant mothers (53.2%) were quite satisfied, 45 pregnant mothers or about 41.3% were very satisfied and 6 pregnant mothers or about 5.4% were still unsatisfied on the service provided. It could be concluded that 53.2% patients were quite satisfied to the Integrated ANC service in Senduro Health Center of Lumajang Regency. Keywords: satisfaction; pregnant mother; ANC service
Work Load Evaluation for Determining Human Resources Needs (Study of Emergency Room and General Clinic “Dokterku Taman Gading Clinic” Jember) Edy Kurniawan; Al Munawir; Zarah Puspitaningtyas
Aloha International Journal of Health Advancement (AIJHA) Vol 3, No 7 (2020): July
Publisher : Alliance oh Health Activists (AloHA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/aijha30701

Abstract

The role of humans as a resource in an organization is increasingly believed to be of importance. Human resource planning is deemed necessary in order to improve employee efficiency, effectiveness and productivity. An evaluation of workload is deemed necessary in order to determine effective and efficient work productivity without ignoring the physical and psychological conditions of employees. Workload evaluation is also needed to determine the needs of Human Resources for relevant agencies. Clinic “Dokterku Taman Gading” experiences an increase in visit of patiens from year to year. This can affect employee work productivity so research is needed to evaluate employee workload with the Work Sampling method. This research method used direct observation of work activities on employees. This type of research was used analytic observational research. From a total sample of 4.800 observations, it knew that the productive activity of employees was 3825 (79.7%). The total standard time of each employee of “Dokterku Taman Gading”Clinic ± 1 minute per activity. The standard time per activity will be accumulated to determine the minimum standard service time given to each patient. Keywords: workload evaluation; HR planning; work sampling
Co-Authors . Zulfan Abd, Misswar Abd, Miswar Achmad, Fariz Ade Ananta Pratiwi Adelia Handoko Adinningtyas Intansari Agung Sudrajat Agung_Sudrajat Agung Aini Hidayati Ali Santoso Alimas Jonsa Alloysius Vendhi Prasmoro, Alloysius Vendhi Anang Dwi Atmoko Ancah Caesarina Novi Marchianti Anhar Fazri Asti Nuris ASTUTI, IDA SRI SURANI WIJI Ayik Nikmatul Laili Azka Darajat Bachtiar, Dandi Bagus Indra Kusuma Dear F Sielma Desi Maulida Desy Tariustanti Desy Tariustanti Dewi Rokhmah dian febrianti Edy Kurniawan Elfian Zulkarnain Elfian Zulkarnain, Elfian Erfan Efendi Erma Sulistyaningsih Farida Wahyu Ningtyias, Farida Wahyu Farida Wahyuningtiyas Farizal, Teuku Futri Syam Ghiza J.K. Barqly Hadi Prayitno Hartati, Rita Hasdi, Syaiful Hazmi Dwinanda Nurqistan Hendri, Afrizal Herdi Susanto Herri Darsan Hilda Khairinnisa I Gusti Ngurah Agung Darma Putra Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Ikmala, Riskita Isa Marufi ISLAMI, SHOFI IQDA Jayadi, Farid Jumanto Jumanto Kamarullah Kamarullah Kiky Martha Ariesaka kustin uds Laili, Ayik Nikmatul laili, Ayik Nikmatul Laksmi Indreswari Luluk Faridatul Mukaromah Mahmuddin Marbun Maidi Saputra Masykur, Masykur Meylis Safriani Mirza Adia Nova Muazar, Muazar Mudzakkir Taufiqurrahman Muflikhatun, Khanif Muhammad Abrar Muhammad Aqib Husni Fadhli Muhammad Arif Nasution Muhammad Herizal Ihza Muhendra, Rifki Mulkan, Andi Murhaban Murhaban Murtadho Ridwan Muzakkir Muzakkir N. Nazaruddin Nadia Putri Yurianto Nafolion Nur Rahmat, Nafolion Nur Nanda Prima Natasya Febrilia Yulianti Novan K. Adji Pandan, Pandan wangi Pipiet Wulandari Putri Erlinda Kusumaningarum Putri Kemala Sari Putri, Gusfita Trisna Ayu Raudhatun Nafisah Retno Widyastuti Riskita Ikmala Rita Fazlina Rizka N Wardani Rizki, Julia Roat Yeti Mustafida Romadhon, Nadia Jean Rosita Dewi Rudy Gunawan Sabrina M Pratama Safrirullah Safrirullah Saiful Bukhori Saiful Bukhori, Saiful Bukhori Salman Al Farisi Sarwendah Siswi Winasis Sayyidah Auliany Aminy Sekar Arum Srigati septa surya wahyudi, septa surya SHOFI IQDA ISLAMI Sihaan, Josua Cornel Roni Silvi Ahmada Chasya Solihin Solihin Solihin, Solihin Solihin Sri Wahyu Handayani Sugiyanta Sugiyanta Sukhairi, Teuku Ariessa Supangat Supangat Supangat Supangat Supangat Syahrul Fathi Syari, Zammiq Utami, Nastiti Bekti Vita Alfiatul Hasanah Wahyu Dian Puspita Widyantoro, Murwan Wiqodatul Ummah Yasrizal Zahrah Febianti Zakir Husin Zarah Puspita Zarah Puspitaningtyas Zuhrizal Fadhly Zulfadhli Zulfadhli Zulfan Adi Putra