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Drug and cosmetic safety training for cadres of family welfare program Tristiana Erawati; Dewi Melani Hariyadi; Noorma Rosita; Widji Soeratri; Tutiek Purwanti; Hadi Poerwono; Marcellino Rudyanto; Helmy Yusuf; Djoko Agus Purwanto; I Nyoman Wijaya
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 9 No. 2 (2024): May 2024
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v9i2.11161

Abstract

In order to increase public understanding and awareness regarding the safety use of drugs and cosmetics, the Community Service Team of the Faculty of Pharmacy, Airlangga University has held community service in Jonggrangan Village, Klaten, Central Java. The community service was carried out on July 31, 2023, with approximately 60 family welfare programs or PKK cadres and health cadres participating through training, presentations, and discussions. The activity began with a pre-test, continued with training, a presentation of the material by three experts, and a discussion, then ended with giving a post-test to the participants. The results of the pre and post-test analysis showed that participants' understanding increased. The results of the analysis of the answers to the 15 questions given showed that the increase in participants' understanding ranged from  2.13-46.02 percent. The impact of these activities on society. The increase in participants' understanding of each topic is not the same depending on the initial understanding. However, the problem is that the level of public understanding after receiving training is still below 50 percent namely on topics about the stages of using cosmetic products and about drug classification. So it is necessary to deepen the material using other strategies (appropriate methods and media).
PEMBERDAYAAN MASYARAKAT KABUPATEN TANGGAMUS LAMPUNG DALAM EKSPLORASI POTENSI KOPI DAN HASIL SAMPINGNYA SEBAGAI PRODUK KESEHATAN Annuryanti, Febri; Wijaya, I Nyoman; Miatmoko, Andang; Rosita, Noorma; Purwanto, Djoko Agus
TRI DHARMA MANDIRI: Dissemination and Downstreaming of Research to the Community (Journal of Community Engagement) Vol 6 No 1 (2026)
Publisher : SMONAGENES Research Center, Univeritas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtridharma.2026.006.01.35

Abstract

Kelurahan Gisting Atas, Kecamatan Gisting, Kabupaten Tanggamus, Lampung, merupakan kawasan dataran tinggi yang dikenal memiliki potensi pertanian kopi yang subur. Meskipun produksi kopi di wilayah ini terus meningkat, namun pendapatan masyarakat belum mengalami peningkatan yang signifikan. Salah satu faktor penyebabnya adalah kurangnya kreativitas dalam mengolah limbah kulit ari kopi. Kegiatan pengabdian masyarakat yang dilaksanakan oleh Tim Pengmas Fakultas Farmasi Universitas Airlangga bertujuan untuk memberdayakan masyarakat setempat melalui pelatihan pembuatan produk berbasis kopi, seperti clay mask dan body scrub, yang dapat meningkatkan nilai jual kopi dan membuka peluang usaha baru. Selain itu, kegiatan ini juga meliputi penyuluhan tentang cara penyimpanan kopi yang benar guna menjaga kualitas dan daya jual kopi yang lebih tinggi. Pelatihan diikuti oleh 40 petani kopi dari Kelompok Tani Hutan Wira Karya Sejahtera 1, dengan evaluasi pemahaman peserta melalui pre-test dan post-test. Hasil dari kegiatan ini diharapkan dapat mengurangi ketergantungan pada penjualan kopi mentah, meningkatkan pendapatan masyarakat, serta mendorong diversifikasi produk kopi yang lebih inovatif. Program ini juga sejalan dengan upaya pemerintah Provinsi Lampung dalam meningkatkan perekonomian daerah dan mendukung pencapaian Tujuan Pembangunan Berkelanjutan (SDG), khususnya SDG 3 (Kesehatan yang Baik dan Kesejahteraan) dan SDG 8 (Pertumbuhan Ekonomi yang Inklusif dan Berkelanjutan).
The Effect of Thymoquinone on Progressive Brain Damage: An Experimental Study in a Wistar Rat Model of Intracerebral Hemorrhage Khamim Thohari; Asra Al Fauzi; Djoko Agus Purwanto
Borneo Journal of Pharmacy Vol. 9 No. 2 (2026): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v9i2.10849

Abstract

Background: ICH accounts for 20% of stroke cases, with a mortality rate of 40-50%. Despite available agents such as citicoline and piracetam, neuroprotective therapy for ICH remains unsatisfactory. TQ, the main active compound of Nigella sativa, has antioxidant and anti-inflammatory properties, but its role in ICH has not been studied. Objective: To evaluate the effect of thymoquinone on inhibiting the progression of brain damage in a Wistar rat model of ICH and to explore potential mechanisms Methods: Male Wistar rats (n=55, 200–220 g) were randomly assigned to five groups: control (no treatment), ICH without thymoquinone (terminated immediately), ICH with corn oil (terminated after 7 days), and ICH with thymoquinone at doses of 150 and 250 mg/kg body weight orally for 7 days (terminated after 7 days). ICH was induced by autologous blood injection (0.12 ml) into the brain parenchyma. Brain and serum samples were analyzed for NLRP3, TNF-α, IL-6, IL-1β, MMP-9, SOD, MDA, and necrotic cells using ELISA, immunohistochemistry, and histology. Statistical analyses included univariate analysis, Shapiro–Wilk, Kruskal–Wallis, and Mann–Whitney U tests. Results: TQ administration significantly altered MMP-9 levels (p=0.000), which increased compared with untreated ICH. TQ was associated with reductions in NLRP3, TNF-α, and IL-1β, while increasing SOD activityMDA levels remained elevated. These effects were dose-dependent, with the most consistent changes observed at 250 mg/kg. Conclusion: TQ modulated inflammatory and oxidative pathways in ICH and unexpectedly upregulated MMP-9, suggesting a dual role in early injury and later tissue remodeling. These findings support TQ as a potential natural neuroprotective agent.
Co-Authors A Fahmy Arif Tsani A. Toto Purnomo Abby Rahmat Kamaruzzaman Abdurahman Abdurrahman Achmad Fuad Hafid Achmad Toto Poernomo Achmad Toto Purnomo Adecha Ekalipta Primazafira Adi Utarini Afra, Fairuz Yaumil Agustina, Indri Alief Putriana Rahman Andang Miatmoko Anggita Mirzautika Anita Natalia Suryawijaya Annuryanti, Febri Asra Al Fauzi Asri Darmawati Asri Darmawati Aty Widyawaruyanti Audrey Gracelia Riwu Augustien, Nora Budi Suharjo Budi Wikeko Christina Destri Devanus lahardo Devi Eka Juniarti Dewi Isadiartuti Dewi Melani Hariyadi Erwin Astha Triyono Esti Hendradi Fairuz Yaumil Afra Fauziyah, Riska Salfa Firman Wicaksana Guniarti Guniarti Guniarti Hadi Poerwono Hadi Suhardjono Hanifah Ridha Rabbani Heny K Daryanto Herin Mawarti Hidayati, Agriana Rosmalina Hilkatul Ilmi I Nyoman Wijaya I NYOMAN WIJAYA Innisa, Deana Rohali Ira Widjiastuti Isnaeni Isnaeni Isnaeni Iswajuni, Iswajuni Joewono Soeroso Juni Ekowati Jusak Nugraha Khamim Thohari Kun Ismiyatin M. Rasjad Indra Mangestuti Agil Marcellino Rudyanto Masruratos Zahroh Maylisa Natalia Corry Melanny Ika Sulistyowaty Mirzautika, Anggita Muhammad Amin Muhammad Amir Hasan Muslihatin, Wirda Narendrani Sasmitaning Edhi Noorma Rosita Nora Augustien Pribadi, Didik Huswo Purwaningsih - Purwitasari, Neny Retno Pudji Rahayu Retno Widyowati Riesta Primaharinastiti Rufaidah Azzahrah Saribatiara, Saribatiara Setyabudi Setyabudi Soraya Aulia Sri Iswati Suciati Suciati Sukardiman Sukardiman Susetyowati Susilowati Susilowati Sutini Tiara Sukmawati Toto Sudargo Tri Widiandani Tristiana Erawati Munandar Tutiek Purwanti Ujang Sumarwan Wibowo, Nadya Khadijah Widiwurjani Widji Soeratri Widji Soeratri Yayuk Hartriyanti Yudianingtyas, Deanur Yusniasari, Putri Antika Yusuf, Helmy