Article Per Year (5 Year)
p-Index From 2021 - 2026
3.743
P-Index
This Author published in this journals
All Journal Journal of Food and Pharmaceutical Science Jurnal Farmasi Klinik Indonesia Profesi Pendidikan Dasar INDONESIAN JOURNAL OF PHARMACY Jurnal Surya Medika JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmaseutik Edukasi : Jurnal Penelitian dan Artikel Pendidikan Jurnal Skala Kesehatan JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline UNTAG Law Review Jurnal Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) Proceedings Series on Social Sciences & Humanities Media Farmasi Indonesia Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Indonesia Journal of Food and Pharmaceutical Sciences Usadha Journal of Pharmacy Indonesian Journal of Pharmacology and Therapy EDUKASI : Jurnal Penelitian dan Artikel Pendidikan
Fita Rahmawati
Faculty of Pharmacy, Universitas Gajdah Mada. Yogyakarta, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 39 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 39 Documents
Search

 1   2   3   4 
Problem Kompatibilitas dan Stabilitas Pencampuran Sediaan Intravena Pada Pasien Anak di RSUP Dr. Sardjito Rahmawati, Reza; Rahmawati, Fita; Azhar Syed Sulaiman, Syed
Jurnal Farmasi (Journal of Pharmacy) Vol. 7 No. 1 (2018): Jurnal Farmasi (Journal of Pharmacy), October 2018
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Inappropriate preparation and administration intravenous drug may caused harm and therapeutic failure for the patient. In pediatric patient, intravenous drug administration is very critical because of poor venous access especially when simultaneously drug administration required which is can lead into incompatibilities occurence. Errors in intravenous drug administration can affect the drug stability also. Therefore, this research aims to investigate the prevalence of incompatibility and stability in pediatric hospitalized patient. This research was done with prospective study at RSUP Dr. Sardjito in Pediatric Intensive Care Unit (PICU) and pediatric ward from November-December 2017. Data collection was done with pediatric hospitalized patient that used at least 1 intravenous drug. Compatibility and stability were analyzed using standard reference Handbook of Injectable Drugs and other references. A total pediatric hospitalized patients are 75 patients, 34 patients are from PICU and 41 patients are from pediatric ward. Intravenous drugs used are 49.1% with the mean of intravenous drugs are 3.3 drugs/patient. Compatible drug combinations are 73.3% and unknown are 26.3%. There are no incompatible drug combination found in this research. Stability problems were found in 3 drug combination that administered by continuous infusion.
Problem Kompatibilitas Pemberian Obat secara Intravena pada Pasien di Intensive Care Unit Haqoiroh; Rahmawati, Fita; Azhar Syed Sulaiman, Syed
Jurnal Farmasi (Journal of Pharmacy) Vol. 7 No. 1 (2018): Jurnal Farmasi (Journal of Pharmacy), October 2018
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Intravenous administration of drugs is commonly used in hospitals patients who need rapid pharmacological effects or when patients can not take oral administration. Preparation for intravenous administration of drugs need special condition because there are some risks include incompatibilities. The aim of this study is to investigate the prevalence of intravenous drug incompatibilities such as drug incompatibilities in Intensive Care Units patients at RSUP Dr. Sardjito and UGM Hospital, and to find the risk factor that affect of drug incompatibilities such as length of hospital stay, number of drugs, and caused of hospitalization.This study was a cross-sectional, prospective, and multicenter in RSUP. Dr. Sardjito and Academic UGM Hospital, Yogyakarta. The location of this study were in ICU, ICCU, and HCU. The prevalence of potential drug incompatibility were analyzed with description statistics and the association between potential incompatibilities and risk factors will be investigated using student t test and ANOVA with 95% confidence interval. 65 patients were collected from this research. The prevalence of potential drug incompatibilities (PI) were found in 28 prescriptions with ratio PI 2.4 incompatibility/patient. The highest incompatibility type was precipitation of 42 (83,35%) and the most precipitating drug pairs are fentanyl and phenytoin; midazolam and phenytoin. The number of drugs were significantly related with PI.
Nurses' knowledge and management of incompatibility issues in intravenous pharmaceutical preparations Rahmawati, Fita; Erna Prasetya Ningrum; Marlyn Dian Laksitorini; Endang Lukitaningsih
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.312

Abstract

Administering multiple intravenous (IV) preparations through a single catheter line can lead to incompatibility issues, such as precipitation. Precipitation can be avoided with sufficient knowledge by nurses during the administration of IV preparations to patients. This research aims to assess nurses' knowledge and management of incompatibility issues in IV pharmaceutical preparations. This non-experimental research collected data through interviews with healthcare professionals (nurses). The research was conducted at Sultan Agung Islamic Hospital, Semarang. A total of 14 healthcare professionals (nurses) who reconstituted and administered IV pharmaceutical preparations to patients in the Intensive Care Unit (ICU) participated in the research. The results revealed that 13 nurses (92.9%) encountered incompatibility incidents with seven types of drugs. Five nurses (29.4%) reported incompatibility issues with cefoperazone. The most frequently observed incompatibility was color change, reported by seven nurses (53.8%), such as white spots appearing during phenytoin reconstitution and discoloration in IV pharmaceutical preparations of cefoperazone and ceftriaxone. The most common approach to addressing incompatibility was replacing the preparation, reported by six nurses (46.2%). The management of incompatibility issues varied among nurses, even when dealing with the same pharmaceutical preparation. Therefore, training on sterile preparation incompatibility should be provided to all healthcare professionals to establish a standardized operational procedure (SOP) for handling incompatibility in IV pharmaceutical preparations.
Treatment of the cytokine storm in COVID-19: review of clinical pharmacology Sapriati, Aisyah Nur; Rahmawati, Fita; Nuryastuti, Titik
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 2 (2023): J Sains Farm Klin 10(2), Agustus 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.2.162-183.2023

Abstract

The cause of the COVID-19 pandemic can be attributed to the Acute Respiratory Syndrome Virus-2 (SARS-CoV-2). COVID-19 manifests with severe symptoms in the upper respiratory tract and can progress to a critical condition due to an acute hyperinflammatory response that triggers a cytokine storm. The cytokine storm refers to an excessive or impaired production of proinflammatory cytokines, resulting in immune dysregulation and uncontrolled inflammatory activity. To effectively address the hyperinflammatory state induced by SARS-CoV-2 infection, it is imperative to explore promising strategies aimed at overcoming the cytokine storm, such as the prompt initiation of anti-inflammatory therapy. Several classes of drugs can potentially prevent the deterioration of COVID-19 patients by mitigating immune system dysregulation and suppressing uncontrolled inflammatory responses. These drug classes encompass corticosteroids, chloroquine and hydroxychloroquine, inhibitors of interleukin-1 (IL-1), inhibitors of interleukin-6 (IL-6), inhibitors of tumor necrosis factor (TNF), and anti-inflammatory drugs. Additionally, tumor necrosis factor alpha (TNF-α) inhibitors, as well as inhibitors targeting the Janus kinase signaling pathway and activator of transcription (JAK/STAT), have exhibited efficacy in treating COVID-19. This efficacy is evident when considering the drug's mechanism of action and pharmacokinetics, while also taking into account the tolerable side effects associated with their usage
Efek Samping Obat Gefitinib pada Pasien Kanker Paru dengan Epidermal Growth Factor Receptor (EGFR) Mutasi Positif Parwatininghati, Ni Putu; Rahmawati, Fita; Sajinadiyasa, I Gede Ketut
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 2 (2023): J Sains Farm Klin 10(2), Agustus 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.2.238-247.2023

Abstract

Deteksi mutasi Epidermal Growth Factor Receptor (EGFR) pada pasien kanker paru akan membantu dalam pemilihan targeted therapy yaitu gefitinib. Studi mengenai evaluasi profil keamanan gefitinib di Indonesia sangat terbatas sehingga penelitian ini bertujuan untuk mengetahui efek samping obat hematologi dan non hematologi dari gefitinib pada pasien kanker paru dengan EGFR mutasi positif. Rancangan penelitian adalah observasional cross sectional. Data sekunder diambil melalui rekam medis tahun 2020 sampai 2022 pada 44 pasien. Probabilitas efek samping obat diukur dengan Naranjo Adverse Drug Reaction Probability Scale dan tingkat keparahan efek samping obat dinilai menggunakan Common Terminology Criteria for Adverse Events (CTCAE). Hasil penelitian menunjukkan efek samping hematologi yang paling sering muncul adalah anemia grade 1 pada 18 pasien (40.91%). Pada efek samping non hematologi, rash grade 2 mendominasi pada 20 pasien (45.46%), 14 pasien (31.82%) mengalami peningkatan serum transaminase grade 1, diare grade 1 terjadi pada 5 pasien (11.36%) dan mual muntah grade 2 dialami oleh 3 pasien (6.82%). Total 36 pasien (81.82%) mengalami efek samping dengan 19 kejadian termasuk kategori possible dan 17 kejadian termasuk kategori probable. Efek samping yang muncul bersifat ringan, dapat ditangani dan tidak kumulatif. Tidak didapatkan penyesuaian dosis atau penghentian penggunaan obat yang disebabkan oleh efek samping obat.
Badai Sitokin pada Covid-19: Ulasan Naratif: Cytokine Storm in Covid-19: Narative Review Sapriati, Aisyah Nur; Rahmawati, Fita; Nuryastuti, Titik
Jurnal Surya Medika (JSM) Vol. 10 No. 1 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i1.7243

Abstract

SARS-Cov-2 adalah virus yang dapat menyebabkan terjadinya penyakit COVID-19 yang parah yang terkait dengan peningkatan produksi sitokin/kemokin proinflamasi. Badai sitokin adalah pelepasan sitokin proinflamasi yang berlebihan atau tidak terkendali yang menyebabkan kekacauan pada sistem kekebalan tubuh dan respon inflamasi yang tidak terkendali. Artikel ini dibuat dengan tujuan untuk memberikan pemahaman terkait badai sitokin, patofisiologi yang menyertainya, manifestasi klinis, pengukuran laboratorium, dan faktor-faktor yang memicu terjadinya badai sitokin. Badai sitokin pada COVID-19 ini menyebabkan terjadinya kegagalan multi-organ bahkan kematian. Faktor-faktor yang menyebabkan terjadinya badai sitokin pada pasien COVID-19 ini bukan saja disebabkan oleh adanya SARS-CoV-2 tetapi adanya factor pendukung lain seperti usia yang lebih tua, jenis kelamin laki-laki, golongan darah A serta adanya gangguan metabolisme pada pasien seperti peningkatan tekanan darah, obesitas maupun diabetes.
Development of the smartphone application for patients with dementia: a literature review Utami, Pinasti; Rahmawati, Fita; Astuti; Zullies Ikawati
Indonesian Journal of Pharmacology and Therapy Vol 5 No 1 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.9596

Abstract

Primary technological developments are advancing rapidly, and dementia patients and caregivers are becoming more open to online interactions for enhancing dementia care. However, most existing applications only focus on patients, and there is a need to expand their scope to include caregivers. Ideally, the application should be designed with the caregiver in mind, and considering the impact they experience while caring for dementia patients. Families are specifically targeting caregivers who are at the highest risk of experiencing caregiver burnout, such as those caring for patients. This literature review described the necessary functions and content for dementia caregivers, serving as a reference for designing, developing, and implementing smartphone solutions that meet user needs. This review utilized articles from three databases i.e. PubMed NCBI, ScienceDirect, and Tandfonline. The Boolean approach method was used to generate the exact keywords. The inclusion criteria for this study encompassed smartphone applications for dementia patients, focusing on function and content, published in English-language journals within five last years, with an emphasis on original research and free full access. In this review, six articles were obtained. From these six articles, four findings related to functions and content were identified i.e. education, interactive health promotion, interaction stakeholder, and referencing information sources. These four aspects could serve as references for developing comprehensive smartphone applications for caregivers, and facilitating integrated health care.
EFEKTIVITAS PAIKEM GEMBROT MELALUI MEDIA WAYANG UNTUK MENINGKATKAN HASIL BELAJAR SISWA Rahmawati, Fita; Mashar, Riana; Mahardika, Astuti
Edukasi: Jurnal Penelitian dan Artikel Pendidikan Vol 6 No 12 (2014): Vol. 6 No. 12, Juni 2014
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The research is supposed toknow applying Paikem Gembrot Approach using wayang to improve student’s ability in sains’learning in Ar Risalah Islamic Elementary School Secang. Type of this research is Classroom Action Research (CAR) that was adapted from Kemmis and Mc Taggart model with two cycle. Every cycle consisted of planning, acting, observation and reflection. Subject of the reseacrh are students of Ar Risalah Islamic Elementary School in grade III about 29 students.Technique of collecting data are test, observation and documentation. Result of the research had shown that Paikem Gembrot Approach using wayang gave positif effect for increasing score and ability in Sains’Learning. That was prove from the averrage of Sains score, it was increasing in every cycle. Score of the students before treatment about 62, 93 with the percentage 24,13%. In cycle I it was increasing became 74,48 with the percentage 58, 62%. In cycle II there was significant increasing became 89, 65%. Based on result of the research, it was concluded that with applying Paikem Gembrot Approach using Wayang can increase result in Sains’Learning with the discussion about the way to conserve the natural environment in grade III Ar Risalah Islamic Elementary School Secang.
Review artikel: Gambaran Penggunaan Pompa Proton Inhibitor (PPI) Sebagai Profilaksis Stress Ulcer Di Unit Perawatan Intensif Wulandari, Dewi; Nugroho, Agung Endro; Rahmawati, Fita
Majalah Farmaseutik Vol 21, No 4 (2025): in press
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v21i2.98109

Abstract

Stress ulcer merupakan cidera mukosa lambung mulai dari erosi hingga ulkus yang biasanya terlihat pada pasien kritis di intensive care unit (ICU).  Untuk mencegah perdarahan saluran cerna (stress ulcer) maka membutuhkan agen profilaksis stress ulcer. Agen terapi yang banyak digunakan sebagai profilaksis stress ulcer pada pasien perawatan intensif adalah pompa proton inhibitor contohnya omeprazole, pantoprazole, lansoprazole, dan esomeprazole. Kajian ini bertujuan untuk melihat efektivitas antara golongan PPI  sebagai profilaksis stress ulcer. Kajian ini merupakan tinjauan naratif (narrative review) yang dilakukan dalam empat tahapan berbeda diantaranya identifikasi kata kunci, penetapan kriteria inklusi dan eksklusi, pemilihan literatur yang relevan, dan analisis hasil. Pencarian informasi yang dilakukan dengan mengumpulkan database elektronik seperti Google Scholar, Pubmed, dan Scopus dari tahun 2014 hingga 2024. Efektivitas penggunaan PPI sebagai profilaksis stress ulcer yang diamati dengan melihat tidak adanya kejadian perdarahan pada saluran cerna.
Co-Authors Abdullah, Ramez Agung Endro Nugroho Almira, Deta Anggriani, A. Anna Wahyuni Widayanti Annafiatuzakiah Annafiatuzakiah Arief Nurrochmad Arini, Yovita Dwi Astri Herawati, Astri Astuti Astuti Mahardika Astuti, Surya Yuli Aulia Fitri, Aulia Azhar Syed Sulaiman, Syed Azni, Meicella Bathari, Anggraini Citra Ryshang Chairun Wiedyaningsih Dewi Wulandari Djoko Wahyono Dwiningrum, Arissa Ejaz, Sundas Ejaz Ellykusuma, Nany Yusuf Ellykusuma, Nany Yusuf Endang Lukitaningsih Endang Yuniarti Erna Prasetya Ningrum Fitri Wulandari Fortuna, Tista Ayu Gunarsih, Vidiya Haqoiroh Hidayah, Astika Nurul I Dewa Putu Pramantara I Gede Ketut Sajinadiyasa Ihsan, Mawardi Ika Puspita Sari Irnayanti, Irnayanti Ismayati, Dwi Jatiningsih, Setiyati Kartika Widayati Taroeno Hariadi Kurniawati, Fivy Lily Annisa, Lily Lukman Hakim Lupitaningrum, Dita Marina Mahmuda, Hartati Marlyn Dian Laksitorini Marlyn Dian Laksitorini, Marlyn Dian Maya Arfania Mayasari, Gita Medisusyanti, Amalia Suci Megawati, Sefi Mpila, Deby Afriani Mukrinin, Walit Uhkri Mulyani, Tuty Mustafidah, Nasikhatul Nanang Munif Yasin Neneng Ratnasari NSH, Maria Caecilia Nurcahya, Bekti Meilani Nurcahya, Bekti Meilani Nurlena Ikawati, Nurlena Oktasari, Sholikhah Rosvita PALUPI, Poppy Diah Parwatininghati, Ni Putu Pinasti Utami, Pinasti Presticasari, Hardiyani Probosuseno Probosuseno, Probosuseno Purwaningsih, Avianti Eka Dewi Aditya Puspitasari, Winda Dwi Putra, Aditya Maulana Perdana R.A. Oetari, R.A. Radiyanti, Radiyanti Rahayu, Asri Rahmawati, Reza Retno Murwanti Riana Mashar Rina Mutiara, Rina Robosuseno, Robosuseno Rukminingsih, Fef Salamah, Ardhanarishwari Umi Sammulia, Suci Fitriani Sapriati, Aisyah Nur Sari, Ernika Sari, Laras Ratna Sari, Ratih Pratiwi Septiani, Ana Maulida Siradjuddin, Ammar Syed Azhar Syed Sulaiman, Syed Azhar Syed Titik Nuryastuti Tri Murti Andayani Triananingsih, Novi Udhiyati, Aida Wahab, Izyan Abdul Willi Wahyu Timur Yoga, Bambang Hastha Yulia Maftuhah Hidayati