Article Per Year (5 Year)
p-Index From 2021 - 2026
2.447
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Microbiology Indonesia Health Science Journal of Indonesia Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Prosiding Seminar Biologi Jurnal Sumberdaya Hayati Indonesian Journal of Cancer The Indonesian Biomedical Journal Molecular and Cellular Biomedical Sciences (MCBS) Acta Biochimica Indonesiana Jurnal Ilmu Kefarmasian Indonesia The New Ropanasuri Journal of Surgery Muhammadiyah Journal of Geriatric Indonesian Journal of Cancer eJournal Kedokteran Indonesia Makara Journal of Science Nanggroe: Journal Of Scholarly Service Molekul: Jurnal Ilmiah Kimia Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Biomedika Jurnal Info Kesehatan
Mohamad Sadikin
Department Of Biochemistry And Molecular Biology, Center Of Hypoxia And Oxidative Stress Studies, Faculty Of Medicine, Universitas Indonesia, Jakarta
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 41 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 41 Documents
Search

 1   2   3   4   5 
Detection of latent tuberculosis infection in household contacts of drug-resistant tuberculosis patients using interferon-gamma release assay: a study at Universitas Indonesia Hospital Muhammad Faris Indratmo; Diah Handayani; Ardiana Kusumaningrum; Febriana Catur Iswanti; Mohamad Sadikin
Acta Biochimica Indonesiana Vol. 8 No. 2 (2025): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.214

Abstract

Background: Drug-resistant tuberculosis (DR-TB) poses significant public health challenges in Indonesia. Household contacts of DR-TB patients face elevated risk of Mycobacterium tuberculosis infection, which may remain latent and asymptomatic. Objective: This study aimed to assess the prevalence of latent tuberculosis infection (LTBI) among household contacts of DR-TB patients using interferon-gamma release assay (IGRA). Methods: This cross-sectional study was conducted at Universitas Indonesia Hospital from February to May 2023. Eighteen asymptomatic household contacts from six confirmed DR-TB index cases were enrolled. Participants underwent clinical evaluation, chest radiography, and LTBI screening using the QuantiFERON-TB Gold Plus (QFT-Plus) assay. Results: Among 18 participants (mean age 33.3 years; 55.6% female), 8 (44.4%) tested positive for LTBI, while 10 (55.6%) tested negative. The highest IGRA positivity rates were observed in adolescents aged 12–16 years (66.7%) and young adults aged 17–25 years (60.0%). All participants were clinically asymptomatic with normal chest radiographs. Conclusion: This study demonstrates substantial LTBI prevalence among household contacts of DR-TB patients. The findings underscore the importance of systematic contact tracing, IGRA-based screening, and timely tuberculosis preventive therapy to reduce disease transmission and progression in high-risk populations.
Co-Authors . RUSDI . Rusdi Ahmad A. Jusuf Ahmad Aulia Ahmad Aulia Jusuf Ahmad R. Utomo Aldri Frinaldi Amarila Malik Andi N.K. Syarifin, Andi N.K. ANDREW ROBERT COSSINS Angelina Stevany Regina Masengi Ani R. Prijanti Ani Retno Prijanti Ardiana Kusumaningrum Arfat Lusinanto Arief Budi Witarto Aryenti . Asri Rasad Astutiati Nurhasanah ASTUTIATI NURHASANAH Bethy S. Hernowo Caroline T. Sardjono CAROLINE TAN SARDJONO Cicia Firakania, Cicia DARYL ROBERT WILLIAMS Dewi Sukmawati Diah Handayani Diah Iskandriati Dian R. Laksmitawati Dian Ratih Laksmitawati Dwirini Retno Gunarti Dwirini Retno Gunarti Ekawati, Maria Evy Ayu Arida Fanny Septiani Farhan Febriana C. Iswanti Febriana Catur Iswanti Franciscus D. Suyatna Frans Ferdinal Frans Ferdinal HANIFAH RAHMI Hans -Joachim Freisleben Hans Joachim Freisleben HANS-JOACHIM FREISLEBEN Heri Wibowo Hermansyah Hermansyah Ichramsyah A. Rahman Ika Superti Daruningrum Indra G. Mansur Indra Gusti Mansur Irawan Satriotomo Jeanne A. Pawitan Jeanne Adiwinata Pawitan Juniarti . KURNIA NUZTIR MANTOLINI Lailan Safina Nasution Lindi G Haritsyah M, Mentari Mohamad Saekhu Muchlis Ramli Muhamad Arif Budiman Muhamad Yusup Muhammad Faris Indratmo Nani Dharmasetiawani Nani Sari Murni Ni Ken Ritchie Nina Fitriana, Nina Ninik Mudjihartini Noorwati Sutandyo Novi S. Hardiany Novi Silvia Hardiany Novianti, Titta Nurhadi Ibrahim Nurhadi Ibrahim Nurjati C. Siregar Oentoeng Soeradi Pamungkas, Joko Panjaitan, Paris Praditi, Citra Radiana D. Antarianto Rahmawati Ridwan Rahmawati Ridwan Ranti Dwi Astriani Reni Paramita Resda Akhra Syahrani Ria Syafitri Evi Gantini Rini Puspitaningrum RONDANG ROEMIATI SOEGIANTO RONDANG ROEMIATI SOEGIANTO RONDANG ROEMIATI SOEGIANTO Rostika Flora Sadikin, Abdul Halim Saleh, Mgs. M. Irsan Samsuridjal Djauzi Sari, Dewi H. SARI, MIKE PERMATA Sarmoko Sarsanti, Pungguri Ayu Nega Sekar Arumsari Septelia I. Wanandi SEPTELIA INAWATI WANANDI Siregar, Nurjati Siti Rahmawati Achyat Sitorus, Novandrik Yeriko Siufui Hendrawan Sri S. Ningsih, Sri S. Sri W.A. Jusman Sri Widia A.Jusman Subandrate Suryani, N. Lilis Syarifah Dewi Syazili Mustofa Tiara Mayang Pratiwi Lio Tiwuk Susantiningsih Tomohiko Yamazaki Trismilah Margono Trismilah Trismilah TRISMILAH TRISMILAH Trismilah, Uly A. Nikmah, Uly A. Vetnizah Juniantito Wahono Sumaryono Wardaya Wardaya Wawan Mulyawan Wawan Mulyawan Wawan Mulyawan Wawan Mulyawan Wawan Mulyawan Wawan Mulyawan Wiwoho, Yudi Yuwono Yalista Fatia Nadia Yefta Moenadjat Yudianita Kesuma, Yudianita Yuhernita . Zen Hafy