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Effects of Green Tea Extract (Camellia sinensis L.) on Blood Biochemical Parameters in Paracetamol-Induced Wistar Rats Galih, Damar; Indriyani, Indriyani; Septiningtyas, Sinta Dwi; Christijanti, Wulan; Susanti, R.; Marianti, Aditya
Jurnal Kebidanan dan Kesehatan Tradisional Jurnal Kebidanan dan Kesehatan Tradisional Volume 11 Number 1 Year 2026
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v11i1.650

Abstract

Background: Paracetamol is one of the analgesics and antipyretics that are widely traded freely, so it is possible that the use is not according to the recommended dose and consumption time. This can trigger liver damage and changes in blood biochemistry. Green tea has components such as antioxidants, anti-inflammatories, and hepatoprotectors. The study aimed to analyze the effect of green tea extract on the blood biochemistry of rats induced by paracetamol. Methods: Laboratory experimental research with the Post-Test Control Group Design method, using 25 male Wistar rats, applying random sampling. Twenty-five rats were divided into 5 groups: K- (control), K+ (positive control), and treatment groups with green tea extract, respectively 175 mg (T1), 350 mg (T2), and 700 mg/kg bw (T3) for 24 days. The treatment group and K+ received paracetamol 600 mg/kg bw on the 14th day for 10 days, and green tea extract was still given. Data, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglycerides (TG), total cholesterol, and leukocyte counts, were analysed using ANOVA and the Least Significant Difference (LSD) test. Results: GTE significantly (p-value <0.05) reduced leukocytes and AST, but inadequate paracetamol induction failed to elevate ALT and lipids, masking GTE’s measurable impact on those specific biochemical parameters. Conclusion: Providing green tea extract was effective in declining the number of leucocytes and AST levels. The study concluded that green tea extract has the potential to influence the biochemical profile of rats induced by paracetamol. Further research is needed regarding the dose and period of administration and exposure.
Menumbuhkan Spirit Toleransi Generasi Mileneal Dalam Mereduksi Isu Primordial Pada Pemilu Tahun 2024 Di Kabupaten Semarang Setiajid, Setiajid; Susanti, Martien Herna; Sumarto, Slamet; Pranoto, Rahel Gloria
Amaliah: Jurnal Pengabdian Kepada Masyarakat Vol 8 No 1 (2024): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPI UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v8i1.2977

Abstract

In the 2024 elections, the use of social media is often used by a number of elites to spread the issue of primordialism based on ethnic, religious, and regional sentiments as a strategy to gain support. Partner problems: (1) the millennial generation's low knowledge about elections; and (2) the high potential for utilization of the millennial generation by participants in the 2024 General Election. The objectives of the service activities are: (1) to provide knowledge about the importance of the intelligent millennial generation in using their right to vote in the 2024 General Election, and (2) to provide awareness of the importance of the spirit of tolerance in reducing primordial issues in the 2024 elections. The method for implementing community education is in the form of socialization. The results of the activity showed that, after participating in the socialization, participants were able to understand the urgency of voting rights and detect hoax news and black campaign information that misled voters. The spirit of tolerance needs to continue to be developed in order to minimize primordial issues that have the potential to cause national disintegration. In conclusion, tolerance is important to ward off issues of primordialism which have a disintegrating impact.
Metagenomic Analysis of Bacterial Communities in Batik Wastewater from Zie Semarang Safitri, Diah Rahma; Susanti, R.
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 2 (2026): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i2.20180

Abstract

This study aims to analyze the abundance profile, diversity of bacterial communities, and their potential as bioremediation agents in batik wastewater. The research method includes analysis of heavy metal levels (Cr, Pb, Cd, and Cu) using the Atomic Absorption Spectrophotometer (AAS) method and metagenomic analysis based on Next Generation Sequencing (NGS) in the target region V3-V4 of the 16S rRNA gene. The AAS test results showed a chromium (Cr) concentration of 0.035 ppm. The metagenomic analysis results produced alpha diversity, namely the Shannon index of 2.749 and Simpson of 0.865, which means that bacterial diversity is in the moderate category with the dominance of certain groups. The bacterial community was dominated by the phyla Pseudomonadota (62.38%) and Actinomycetota (28.61%), which are known to have high adaptation and tolerance to Cr in degrading organic compounds. At the genus level, the highest percentages were found in Rickettsia (30.2%) and Xanthobacter (24.58%). Xanthobacter has potential as a bioremediation agent, but the presence of Rickettsia needs further study because the sample was mixed with other sources containing Rickettsia vectors. This study provides a basis for optimizing bioremediation by utilizing bacteria that have potential as pollutant degraders based on analysis of previous studies.
Dinasti Politik dalam Pilkada di Indonesia Martien Herna Susanti
Journal of Government and Civil Society Vol 1 No 2 (2017): Journal of Government and Civil Society (October)
Publisher : Universitas Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31000/jgcs.v1i2.440

Abstract

Kehadiran dinasti politik yang melingkupi perebutan kekuasaan di level regional hingga nasional tidak terlepas dari peran partai politik dan regulasi tentang Pilkada. Oligarki di tubuh partai politik dapat dilihat dari kecenderungan pencalonan kandidat oleh partai politik lebih didasarkan atas keinginan elit partai, bukan melalui mekanisme yang demokratis dengan mempertimbangkan kemampuan dan integritas calon. Secara bersamaan, dinasti politik terus membangun jejaring kekuasaannya dengan kuat hingga mampu menguasai dan mematikan demokrasi dalam partai politik. Dalam konteks masyarakat juga terdapat upaya menjaga status quo di daerahnya dengan mendorong kalangan keluarga atau orang dekat kepala daerah menggantikan petahana. Regulasi yang lemah untuk memangkas dinasti politik turut menjadi penyebab meluasnya dinasti politik dalam Pilkada. Praktik politik dinasti juga ditengarai menjadikan lemahnya fungsi checks and balances hingga berdampak pada tindakan korupsi yang dilakukan oleh kepala daerah beserta kerabatnya. Tahun 2017 ini merupakan paruh kedua babak baru pemilihan kepala daerah, setelah paruh pertama pada tahun 2015. Sistem Pemilukada memang baru, namun wajah-wajah lama yang tidak lain merupakan keberlanjutan dari dinasti politik mewarnai perhelatan Pilkada ini yang dikhawatirkan dapat mengancam fase transisi demokrasi menuju konsolidasi demokrasi. The presence of political dynasties in power struggles from regional to national level is inseparable from the role of political parties and the regulation of the regional head elections. Oligarchy on the body of a political party can be seen from the tendency of candidates nominating by political parties based more on the wishes of party elites, not through democratic mechanisms by considering the ability and integrity of the candidates. Simultaneously, political dynasties continue to establish solid networks of power so they can dominate and kill democracy within political parties. In the context of society, there is also an effort to maintain the status quo in the region by encouraging families or people close to the head of the region to replace the incumbent. Weak regulation to trim political dynasties has contributed to the widespread political dynasty in the regional head elections. The practice of dynastic politics is also suspected to make the weakness of checks and balances function to the effect of corruption acts committed by the head of the region and their relatives. In the year 2017 is the second half of a new round of regional head elections, after the first half in 2015. The regional head elections system is new, but the old faces that are nothing but the continuity of the political dynasty characterize this Pilkada event which is feared could threaten the phase of democratic transition towards consolidation of democracy.
Co-Authors - Suprapti, - A Yuniastuti A.A. Ketut Agung Cahyawan W Adhi, Nino Aditya Marianti Aji Purwinarko, Aji Ali Rizqi, Nur Kholish Ali Rizqi, Nur Kholish Ana Fitria Ananda, Ananda Anandha Anandha, Anandha Andi Suhardiyanto Andreas Priyono Budi Prasetyo Angga Ari Wibowo Ani Rusilowati Ari Yuniastuti Ariesta, Putri Ariesta, Putri ARIF INDIARTO, ARIF Arlinda, Dyken Dwi Asri, Widi Aulia, Innarotul Aulia, Maliqa Azkiyah, Nimas Catur BAHRAIN DWI MASITHO, BAHRAIN DWI Bahtiar, Denny Herbianto Cahya Buana Cahyati, Widya Hari Cahyo, Reza Dwi Cahyo, Reza Dwi Chasnah Chasnah, Chasnah Chatarina Umbul Wahyuni Christijanti, W. Dafip, M. Dafip, Muchamad Dewi Mustikaningtyas Dewi, Nuriana Rahmani DIAN LESTARI Dimarti, Safira Chaerani Dimarti, Safira Chairani Dita Selviana, Dita Doni Saputro E Hidayat, E E.S.,, Sri Mulyani Endah Peniati ENDANG TRI MARGAWATI Enni Suwarsi Rahayu F Widhi Mahatmanti Fachry Abda El Rahman Falistina, Amna Farikhul Ulum Felintina Yuniarti, Felintina Fidia Fibriana Fifti Istiklaili, Fifti Firdausi, Aulya Della Fitri Arum Sasi, Fitri Arum Fitriya, Farikhatun Nur Galih, Damar Gita Ria Octafia, Gita Ria Hammam, Bagus Hardi Saputro, Iwan Hasani, Azharu Alfi I Gusti Ngurah K Mahardika I Gusti Ngurah Kade Mahardika I Wayan T Wibawan I-W.T Wibawan Ibnul Mubarok Indriawati, Indriawati Indriyani Indriyani Irna Kinayungan, Irna Isnaeni, Lili Astuti Isnaeni, Lili Astuti Isti Hidayah Iswari, R S Jaya, Adi Franata Kenarni, Naina Rizki Kristamtini, K Kusuma, Fitriana Dian Kusuma, Putri Patria Larasanti, Firna Larasanti, Firna Lina Herlina Listiaji, Prasetyo M.T Suhartono Maggy T Suhartono Mahardika Prasetya Aji Maman Rachman Margareta Rahayuningsih Nugroho Edi K Mega Fatimah Rosana Moh. Aris Munandar, Moh. Aris Mohamed, Mohd Salim Bin Mukaromah, Riska Laila Muyasaroh, Kun Maisarotun Na’ima, Mirtaati Nahar, Akhmad Lutfi Nahar, Akhmad Lutfi Naim, Fatchun Nezar, Muhammad Rofiq Ning Setiati Nisa, Farah Fitrotun Nissa, Ma’isyatun Nugrahaningsih Nugrahaningsih Nugrahaningsih WH, Nugrahaningsih Nur Halimah Nur Kusuma Dewi Nur Rahayu Utami Oktaviani, Esa Pauline, Maretha Putri Pramesti Dewi Pranoto, Rahel Gloria Pratiwi, Retno Herningrum Priyantini Widiyaningrum PUJI LESTARI Pukan, Krispinus Putri, Amalia Nurina Putri, Komala Amelia R, Rahmatika Saputri R.D Soejoedono RAHMA FERDIANA, RAHMA Rahmatih, Aisa Nikmah Rahmatih, Aisa Nikmah Rahmawati, Esa Mara Rahmawati, Sinta Kurnia Rakainsa, Senda Kartika Ratih Puspita Dewi, Ratih Puspita Retna Utami Retno D Soejoedono Retno Sri Iswari Rizki Puspita Dewi, Rizki Puspita Rohmah, Amalia Nor Romadhoni, Mar`atush Sholihah RS Iswari S.Pd. M Kes I Ketut Sudiana . Sa’adah, Siti Rofiatus Safitri, Diah Rahma Salfia, Mega Salwa, Khoerina Samsul Nizar Saputri, Aprilia Rizki Saraswati, Ifah Saraswati, Ifah Septiana Anggraini, Septiana Septiningtyas, Sinta Dwi Setiadi, Eka Setiajid Setiajid Setiajid Setiajid, Setiajid Shinta Widyastuti, Shinta Sigit Saptono Siti Harnina Bintari Slamet Sumarto Sri Sukaesih Sri Utami Sriyadi Sriyadi, Sriyadi Sulistyo, Danu Sumarno . Sunarto Sunarto Suryo Pratikwo Suryonegoro, Bayu Murti Sutikno Sutikno Tafrika Donita Talitha Widiatningrum Tijan Tijan, Tijan Tri Budi Kurniawan, Tri Budi Trisna, Mila Tuti Widianti Umi Isnaeni, Umi Utami, Anisa Dyah Utami, Melia Dwi Utomo, Didik Huswo Wahyuni, Desiy Ema Dwi Wardono, Hari Rudijanto Indro Widiyastuti, Karima Widya Hary Cahyati Widyaningrum, Kartika Wijaya, Ifan Badra Wijayanti , Yuni Wiwi Isnaeni Wulan Christijanti Wulandari K. E, Yenni Tyas Yohanes Nong Bunga Yuliana, Lusia Retno Yuliana, Lusia Retno Yuliantika, Atika Yuni Wijayanti Yuniastuti , Ari Yuniastuti, A. Yustinus Ulung Anggraito Zaenafree, Intan Zakyani, Nova N