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Effects of Green Tea Extract (Camellia sinensis L.) on Blood Biochemical Parameters in Paracetamol-Induced Wistar Rats Galih, Damar; Indriyani, Indriyani; Septiningtyas, Sinta Dwi; Christijanti, Wulan; Susanti, R.; Marianti, Aditya
Jurnal Kebidanan dan Kesehatan Tradisional Jurnal Kebidanan dan Kesehatan Tradisional Volume 11 Number 1 Year 2026
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v11i1.650

Abstract

Background: Paracetamol is one of the analgesics and antipyretics that are widely traded freely, so it is possible that the use is not according to the recommended dose and consumption time. This can trigger liver damage and changes in blood biochemistry. Green tea has components such as antioxidants, anti-inflammatories, and hepatoprotectors. The study aimed to analyze the effect of green tea extract on the blood biochemistry of rats induced by paracetamol. Methods: Laboratory experimental research with the Post-Test Control Group Design method, using 25 male Wistar rats, applying random sampling. Twenty-five rats were divided into 5 groups: K- (control), K+ (positive control), and treatment groups with green tea extract, respectively 175 mg (T1), 350 mg (T2), and 700 mg/kg bw (T3) for 24 days. The treatment group and K+ received paracetamol 600 mg/kg bw on the 14th day for 10 days, and green tea extract was still given. Data, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglycerides (TG), total cholesterol, and leukocyte counts, were analysed using ANOVA and the Least Significant Difference (LSD) test. Results: GTE significantly (p-value <0.05) reduced leukocytes and AST, but inadequate paracetamol induction failed to elevate ALT and lipids, masking GTE’s measurable impact on those specific biochemical parameters. Conclusion: Providing green tea extract was effective in declining the number of leucocytes and AST levels. The study concluded that green tea extract has the potential to influence the biochemical profile of rats induced by paracetamol. Further research is needed regarding the dose and period of administration and exposure.
Menumbuhkan Spirit Toleransi Generasi Mileneal Dalam Mereduksi Isu Primordial Pada Pemilu Tahun 2024 Di Kabupaten Semarang Setiajid, Setiajid; Susanti, Martien Herna; Sumarto, Slamet; Pranoto, Rahel Gloria
Amaliah: Jurnal Pengabdian Kepada Masyarakat Vol 8 No 1 (2024): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPI UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v8i1.2977

Abstract

In the 2024 elections, the use of social media is often used by a number of elites to spread the issue of primordialism based on ethnic, religious, and regional sentiments as a strategy to gain support. Partner problems: (1) the millennial generation's low knowledge about elections; and (2) the high potential for utilization of the millennial generation by participants in the 2024 General Election. The objectives of the service activities are: (1) to provide knowledge about the importance of the intelligent millennial generation in using their right to vote in the 2024 General Election, and (2) to provide awareness of the importance of the spirit of tolerance in reducing primordial issues in the 2024 elections. The method for implementing community education is in the form of socialization. The results of the activity showed that, after participating in the socialization, participants were able to understand the urgency of voting rights and detect hoax news and black campaign information that misled voters. The spirit of tolerance needs to continue to be developed in order to minimize primordial issues that have the potential to cause national disintegration. In conclusion, tolerance is important to ward off issues of primordialism which have a disintegrating impact.
Co-Authors - Suprapti, - A Yuniastuti A.A. Ketut Agung Cahyawan W Adhi, Nino Aditya Marianti Aji Purwinarko, Aji Ali Rizqi, Nur Kholish Ali Rizqi, Nur Kholish Ana Fitria Ananda, Ananda Anandha Anandha, Anandha Andi Suhardiyanto Andreas Priyono Budi Prasetyo Angga Ari Wibowo Ani Rusilowati Ari Yuniastuti Ariesta, Putri Ariesta, Putri ARIF INDIARTO, ARIF Arlinda, Dyken Dwi Asri, Widi Aulia, Innarotul Aulia, Maliqa Azkiyah, Nimas Catur BAHRAIN DWI MASITHO, BAHRAIN DWI Bahtiar, Denny Herbianto Cahya Buana Cahyati, Widya Hari Cahyo, Reza Dwi Cahyo, Reza Dwi Chasnah Chasnah, Chasnah Chatarina Umbul Wahyuni Christijanti, W. Dafip, M. Dafip, Muchamad Dewi Mustikaningtyas Dewi, Nuriana Rahmani DIAN LESTARI Dimarti, Safira Chaerani Dimarti, Safira Chairani Dita Selviana, Dita Doni Saputro E Hidayat, E E.S.,, Sri Mulyani Endah Peniati ENDANG TRI MARGAWATI Enni Suwarsi Rahayu F Widhi Mahatmanti Fachry Abda El Rahman Falistina, Amna Farikhul Ulum Felintina Yuniarti, Felintina Fidia Fibriana Fifti Istiklaili, Fifti Firdausi, Aulya Della Fitri Arum Sasi, Fitri Arum Fitriya, Farikhatun Nur Galih, Damar Gita Ria Octafia, Gita Ria Hammam, Bagus Hardi Saputro, Iwan Hasani, Azharu Alfi I Gusti Ngurah K Mahardika I Gusti Ngurah Kade Mahardika I Wayan T Wibawan I-W.T Wibawan Ibnul Mubarok Indriawati, Indriawati Indriyani Indriyani Irna Kinayungan, Irna Isnaeni, Lili Astuti Isnaeni, Lili Astuti Isti Hidayah Iswari, R S Jaya, Adi Franata Kenarni, Naina Rizki Kristamtini, K Kusuma, Fitriana Dian Kusuma, Putri Patria Larasanti, Firna Larasanti, Firna Lina Herlina Listiaji, Prasetyo M.T Suhartono Maggy T Suhartono Mahardika Prasetya Aji Maman Rachman Margareta Rahayuningsih Nugroho Edi K Moh. Aris Munandar, Moh. Aris Mohamed, Mohd Salim Bin Mukaromah, Riska Laila Muyasaroh, Kun Maisarotun Na’ima, Mirtaati Nahar, Akhmad Lutfi Nahar, Akhmad Lutfi Naim, Fatchun Nezar, Muhammad Rofiq Ning Setiati Nisa, Farah Fitrotun Nissa, Ma’isyatun Nugrahaningsih Nugrahaningsih Nugrahaningsih WH, Nugrahaningsih Nur Halimah Nur Kusuma Dewi Nur Rahayu Utami Oktaviani, Esa Pauline, Maretha Putri Pramesti Dewi Pranoto, Rahel Gloria Pratiwi, Retno Herningrum Priyantini Widiyaningrum PUJI LESTARI Pukan, Krispinus Putri, Amalia Nurina Putri, Komala Amelia R, Rahmatika Saputri R.D Soejoedono RAHMA FERDIANA, RAHMA Rahmatih, Aisa Nikmah Rahmatih, Aisa Nikmah Rahmawati, Esa Mara Rahmawati, Sinta Kurnia Rakainsa, Senda Kartika Ratih Puspita Dewi, Ratih Puspita Retna Utami Retno D Soejoedono Retno Sri Iswari Rizki Puspita Dewi, Rizki Puspita Rohmah, Amalia Nor Romadhoni, Mar`atush Sholihah RS Iswari S.Pd. M Kes I Ketut Sudiana . Sa’adah, Siti Rofiatus Salfia, Mega Salwa, Khoerina Samsul Nizar Saputri, Aprilia Rizki Saraswati, Ifah Saraswati, Ifah Septiana Anggraini, Septiana Septiningtyas, Sinta Dwi Setiadi, Eka Setiajid Setiajid Setiajid Setiajid, Setiajid Shinta Widyastuti, Shinta Sigit Saptono Siti Harnina Bintari Slamet Sumarto Sri Sukaesih Sri Utami Sriyadi Sriyadi, Sriyadi Subagyo Subagyo Sulistyo, Danu Sumarno . Sunarto Sunarto Supriyanto Supriyanto Suryo Pratikwo Suryonegoro, Bayu Murti Sutikno Sutikno Tafrika Donita Talitha Widiatningrum Tijan Tijan, Tijan Tri Budi Kurniawan, Tri Budi Trisna, Mila Tuti Widianti Umi Isnaeni, Umi Utami, Anisa Dyah Utami, Melia Dwi Utomo, Didik Huswo Wahyuni, Desiy Ema Dwi Wardono, Hari Rudijanto Indro Widiyastuti, Karima Widya Hary Cahyati Widyaningrum, Kartika Wijaya, Ifan Badra Wijayanti , Yuni Wiwi Isnaeni Wulan Christijanti Wulandari K. E, Yenni Tyas Yohanes Nong Bunga Yuliana, Lusia Retno Yuliana, Lusia Retno Yuliantika, Atika Yuni Wijayanti Yuniastuti , Ari Yuniastuti, A. Yustinus Ulung Anggraito Zaenafree, Intan Zakyani, Nova N