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All Journal Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Jurnal Veteriner Majalah Kedokteran Bandung Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Buletin Farmatera ARSHI Veterinary Letters Vitek : Bidang Kedokteran Hewan Veterinary Biomedical and Clinical Journal Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Current Biomedicine Policy Brief Pertanian, Kelautan, dan Biosains Tropika Indonesian Journal of Jamu
Aulia Andi Mustika
Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary

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Wujudkan Kampus Berkelanjutan melalui Regenerative Waste Governance IPB, BPKB; Mardiana, Rina; Yuwono, Arief Sabdo; Putra, Heriansyah; Febrita, Joana; Amperanoto, Agus; Ekayani, Meti; Purwanto, Budi; Hudaya, Aang; Dwiyanti, Fifi Gus; Qayim, Ibnul; Utami, Annisa Dwi; Sita, Rai; Mustika, Aulia Andi; Abidin, Zaenal; Sari, Windi Mayang; Rifnadhi, Bayu; Rukmana, Adi
Policy Brief Pertanian, Kelautan, dan Biosains Tropika Vol 6 No 3 (2024): Policy Brief Pertanian, Kelautan dan Biosains Tropika
Publisher : Direktorat Kajian Strategis dan Reputasi Akademik IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agro-maritim.0603.959-966

Abstract

IPB University dalam mengimplementasikan visi sebagai perguruan tinggi inovatif dan berkelanjutan, mengadopsi pendekatan regenerative waste governance (tata kelola sampah regeneratif). Pendekatan ini tidak sekedar menitikberatkan pada pengelolaan sampah sebagai beban masalah, melainkan bertujuan menciptakan dampak positif yang bersifat regeneratif terhadap lingkungan dan masyarakat. Beberapa aspek kunci meliputi penerapan model tiga lini tata kelola, pengembalian bahan, desain berkelanjutan, restorasi ekosistem, pemberdayaan komunitas, inovasi teknologi berkelanjutan, siklus hidup produk, dan upaya edukasi peningkatan kesadaran. Tata kelola sampah IPB didukung oleh regulasi dan kebijakan yang telah diimplementasikan, mencakup larangan penggunaan kemasan styrofoam dan plastik, pengurangan sampah kertas, pemilahan sampah, dan program Green Campus. Analisis SWOT (Strengths, Weakness, Opportunities, and Threats) telah mengidentifikasi kekuatan, kelemahan, peluang, dan ancaman dalam pengelolaan sampah IPB. Rendahnya penegakan hukum dan kesadaran warga IPB terkait pemilahan sampah merupakan aspek kelemahan dalam tata kelola sampah IPB saat ini. Peluang peningkatan tata kelola sampah IPB melalui budidaya maggot dan pengembangan produk bernilai bisnis dari sampah anorganik memiliki potensi tinggi untuk dikembangkan. Sementara itu, ancaman terkait kesehatan, penurunan kualitas lingkungan, dan reputasi keberlanjutan IPB memerlukan perhatian khusus. Perbaikan pada pengelolaan limbah B3, pembaruan landasan hukum, dan peningkatan kesadaran warga IPB menjadi hal penting dalam upaya IPB meningkatkan tata kelola sampah regeneratif.
EFEKTIVITAS INFUSA LEMPUYANG GAJAH (Zingiber zerumbet) SEBAGAI ANTIDIARE PADA MENCIT (Mus musculus) Mustika, Aulia Andi
VITEK : Bidang Kedokteran Hewan Vol. 14 No. 2 (2024): VITEK-Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jv.v14i2.293

Abstract

Lempuyang gajah (Zingiber zerumbet) rhizomes have long been consumed as food and treatment of diseases in humans. Lempuyang gajah rhizomes have potential as antidiarrheal that is cheap and easy to find, but there has been no research related to the benefits of lempuyang gajah rhizomes as antidiarrheal. The purpose of this study is to determine the effectivity of lempuyang gajah infusion as an antidiarrheal and the concentration that has the most effective antidiarrheal effect with intestinal protection method. This research also determine the content of secondary metabolites in lempuyang gajah through phytochemical tests. This study used 30 mices divided into five groups consisting of negative control group (Tween 80 [1%]), a positive control group (loperamid HCl suspension), and three groups of treatment with a lempuyang gajah infusion concentration of 25%, 50%, and 100% given orally. The parameters observed were the frequency of defecation, the consistency of faeces, and the duration of diarrhea. The conclusion of this research shows that lempuyang gajah infusion has antidiarrheal effect, lempuyang gajah infusion at a concentration of 50% showed the most effective antidiarrheal effect. Phytochemical test results show lempuyang gajah contains alkaloids and saponins
Efektivitas Infusa Jintan Putih (Cuminum cyminum) sebagai Antidiare pada Mencit (Mus musculus) Fadiela Salima Putri; Aulia Andi Mustika; Rini Madyastuti Purwono; Lina Novianti Sutardi
Jurnal Veteriner dan Biomedis Vol. 3 No. 1 (2025): Maret
Publisher : Sekolah Kedokteran Hewan dan Biomedis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jvetbiomed.3.1.44-50.

Abstract

Jintan putih (Cuminum cyminum) merupakan tanaman yang sudah sejak lama dikonsumsi sebagai bahan masakan dan obat, namun belum terdapat penelitian terkait manfaat jintan putih sebagai antidiare. Penelitian ini bertujuan mengetahui efektivitas infusa jintan putih sebagai antidiare dan menentukan konsentrasi yang memiliki efek antidiare paling efektif. Penelitian ini juga bertujuan mengetahui kandungan metabolit sekunder pada jintan putih melalui penapisan fitokimia. Pengujian antidiare dilakukan dengan menggunakan metode proteksi intestinal dengan pemberian sediaan secara peroral. Parameter yang diamati pada metode proteksi intestinal yaitu frekuensi defekasi, konsistensi feses, dan durasi diare. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok terdiri dari kelompok kontrol negatif (Tween-80 [1%]), kontrol positif (Loperamide HCl), dan tiga kelompok perlakuan infusa jintan putih dengan konsentrasi 25%, 50%, dan 100%. Konsentrasi 25% merupakan konsentrasi jintan putih yang paling efektif, karena menghasilkan durasi diare paling pendek dibandingkan kelompok perlakuan lainnya. Penapisan fitokimia infusa jintan putih menunjukkan bahwa terdapat senyawa metabolit sekunder meliputi alkaloid, saponin, flavonoid, tanin, dengan tanin sebagai senyawa yang paling berpotensi sebagai antidiare.
Efficacy of tamarind leaf infusion (Tamarindus indica L.) as an antidiarrheal agent in mice Nababan, Ratna Kristiani; Sutardi, Lina Noviyanti; Rahma, Anisa; Mustika, Aulia Andi
Current Biomedicine Vol. 3 No. 2 (2025): July
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.3.2.53

Abstract

Asam jawa merupakan tanaman herbal yang memiliki khasiat untuk mengobati berbagai penyakit, namun belum ada penelitian ilmiah mengenai aktivitas infusa daun asam jawa sebagai antidiare. Penelitian ini bertujuan untuk menentukan konsentrasi infusa daun asam jawa yang efektif dalam memberikan efek antidiare pada mencit. Penelitian ini juga bertujuan untuk menganalisis kandungan senyawa metabolit sekunder. Penelitian ini menggunakan 30 ekor mencit yang dibagi menjadi 5 kelompok yang terdiri dari kontrol negatif (Tween 80 [1%]), kontrol positif (Loperamid HCl), dan tiga kelompok yang diberi perlakuan infusa daun asam jawa dengan konsentrasi bertingkat (25%, 50 %, dan 100%). Parameter yang digunakan dalam metode proteksi usus adalah frekuensi buang air besar, konsistensi feses, waktu awal terjadinya diare, durasi, dan waktu penyembuhan diare. Hasil yang diperoleh menunjukkan ekstrak infusa daun asam jawa sebagai antidiare memiliki kemampuan menurunkan frekuensi defekasi, meningkatkan konsistensi feses, mencegah terjadinya diare, dan memperlama waktu penyembuhan diare. Hasil uji fitokimia dari infusa daun asam jawa mengandung flavonoid, steroid, dan terpenoid. Semua kelompok ekstrak infusa daun asam jawa memberikan hasil yang efektif sebagai antidiare.
Effectiveness of Sambiloto Leaf Infusion (Andrographis paniculata Nees.) as an Antidiarrheal in Mice (Mus musculus) Anggraini, Lutvi; Mustika, Aulia Andi; Priosoeryanto, Bambang Pontjo; Sutardi, Lina Noviyanti
Jurnal Jamu Indonesia Vol. 10 No. 2 (2025): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v10i2.350

Abstract

Sambiloto is one of the most diverse herbal plants. The active content found in sambiloto is believed to fight diseases, one of which is diarrhea. This study aimed to determine the content of secondary metabolite compounds with phytochemical tests, the antidiarrheal effectiveness of sambiloto leaf infusa using the intestinal protection method, and the effective concentration of antidiarrheal in mice. This study used 25 mice, which were divided into five groups: control (+), control (-), and three treatment groups of sambiloto leaf infusa with concentrations of 25%, 50%, and 100% given orally. The results of phytochemical tests of sambiloto that have the potential to be antidiarrheal compounds are alkaloids, flavonoids, steroids, terpenoids, saponins, and tannins. The parameters observed were the frequency of defecation and consistency of mice's feces every 30 minutes for 9 hours. The results of this study showed that bitter melon leaf infuse preparations at concentrations of 25%, 50%, and 100% had antidiarrheal activity, with the best antidiarrheal activity shown at a concentration of 25%.
COMBINATION OF BASIL, TURMERIC AND BEAN SPROUTS TO HEMATOLOGY AND BIOCHEMISTRY OF FEMALE RAT BLOOD BEFORE PREGNANCY Andriyanto, Andriyanto; Mustika, Aulia Andi; Manalu, Wasmen; Subangkit, Mawar; Aurelia, Sharon; Widi, Leliana Nugrahaning; Putra, Hamdika Yendri; Tarigan, Elpita; Irarang, Yusa
Jurnal Kedokteran Hewan Vol 17, No 4 (2023): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v17i4.33189

Abstract

The purpose of the study was to examine the safety of combination of basil, turmeric and bean sprouts extract solution on the hematological parameters and blood biochemistry profile of rats. The combined ingredients used in the study were obtained from different places. A total of 15 rats were divided into 3 groups based on the treatment dose. Each group consisted of 5 rats. The rats in control group (K) did not given extract combination, while the rats in group KKT 1 % and KKT 5% received combination of basil, turmeric and bean sprouts extract at dose of 1% and 5%, respectively. Effectiveness and safety tests were carried out by evaluating the hematological and blood biochemical profiles of female rats. The data were analyzed using one-way analysis of variance (ANOVA). The results showed that the rats given combination of basil, turmeric and bean sprouts extract at a dose of 1% and, dose of 5% did not had significant different compared to control (P0.05), but tend to have positive effects in increasing several blood components that play an important role in maintaining immunity during pregnancy. It can be concluded that the combination of basil, turmeric and bean sprouts at dose of 1% and 5% do not adversely affect hematology profile and blood biochemistry of rats. This indicates that the extract combination does not cause any toxicity effects on the rats.
THE EFFICACY OF AVOCADO, MUNG BEAN SPROUTS, AND HOLY BASIL HERB COMBINATION (JAMU ATOKE) ON THE HEALTH AND REPRODUCTIVITY OF ADULT FEMALE RATS Andriyanto, Andriyanto Andriyanto; Widi, Leliana Nugrahaning; Yendri, Hamdika; Mardathilah, Kharisma; Yuliansah, Diky; Agustin, Firda; Mustika, Aulia Andi; Manalu, Wasmen
Jurnal Kedokteran Hewan Vol 16, No 4 (2022): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v16i4.24037

Abstract

The purpose of this study was to examine the efficacy of a herbal combination of avocado, mung bean sprouts, and holy basil (Jamu ATOKE) in optimizing the reproductive health of adult female rats. Eighteen female Sprague Dawley rats aged 9-10 weeks old weighing around 180-250 g, and had not been pregnant previously were equally and randomly divided into 3 groups: one control group and two treatment groups (n= 6 rats per group). The treatment groups received Jamu ATOKE with a concentration of 2.5 and 5%, respectively. Jamu ATOKE was added to the drinking water and consumed by the rats for 30 days prior to pregnancy. Reproductivity (pregnancy success, estrogen and progesterone hormone concentrations), and health performance (body weight gain, food, and water consumption, motor activity, red blood cell (RBC) count, white blood cell (WBC) count and differentials, SGPT, SGOT, ureum, and creatinine) of rats were observed. The results showed that groups receiving the Jamu ATOKE had better reproductive and health performance compared to those of the control group. The administration of Jamu ATOKE can significantly increase the concentration of estrogen and progesterone in rats (P0.05). It can also improve the fertility and health of the female rats prior to pregnancy.
Hepatoprotective Potentials of Dates Extract (Phoenix dactylifera) in Acetaminophen-Induced Mice Andriyanto, Andriyanto; Putra, Hamdika Yendri; Aurelia, Sharon; Mustika, Aulia Andi; Manalu, Wasmen; Subangkit, Mawar; Tarigan, Elpita; Irarang, Yusa
Majalah Kedokteran Bandung Vol 55, No 3 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n3.3155

Abstract

Dates (Phoenix dactylifera) are considered as a well-known fruit consumed by many people in various countries. This study aimed to examine potential effects of dates as a hepatoprotective agent in mice. This study was conducted at the Iratco Group’s eLRosa Laboratory Research Facility, Indonesia, starting from June 2022 to July 2022. Mice from ddY strain were randomly divided into 5 groups (n=5 per group) of positive and negative control groups, and treatment groups 1, 2, and 3. The negative control group as the normal baseline did not receive acetaminophen and date extract. In treatment groups, 30 µL/30 gr BW, 60 µL/30 gr BW,  and 100 µL/30 gr BW extract was given per oral to Treatment Group 1, Group 2, and Group 3, respectively for 20 days. On day 21, all  treatment groups were induced with 300mg/KgBW acetaminophen for 3 days via the intraperitoneal route. Blood tests were performed on day 24 to measure the serum transaminase level as the parameter of liver damage. The lowest level of transaminase serum was found in group 3 with the highest volume of dates extract, which was 100 µL, followed by group 2 (60 µL), and group 1 (30 µL). There was a significant difference between the positive control group and treatment groups with  no significant difference was seen between negative and the treatment groups. This study concludes that dates extract has the potential of being a hepatoprotective agent.
The In Silico Toxicity of Serai Wangi (Cymbopogon nardus) and Mimba (Azadirachta indica anggraeni, Henny endah; Purwono, Rini Madyastuti; Sutardi, Lina Noviyanti; Mustika, Aulia Andi; Manalu, Wasmen; Andriyanto, Andriyanto
Acta VETERINARIA Indonesiana Vol. 13 No. 3 (2025): November 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.3.278-285

Abstract

Natural active-ingredient-based shampoos offer an effective and eco-friendly solution for maintaining the skin and hair health of companion animals. This study aimed to predict the toxicity of phytochemical compounds from citronella oil (Cymbopogon nardus) and neem oil (Azadirachta indica) using an in silico approach with the ProTox-II platform. The analyzed compounds included limonene, farnesene, eucalyptol, menthol, oleic acid, p-cymene, indole, (9Z)-9- octadecenamide, amylbenzene, p-cresol, camphor, and dieugenol, selected based on LC-MS/MS analysis. The evaluated toxicological parameters comprised oral acute toxicity (LD50), hepatotoxicity, immunotoxicity, genotoxicity (cytotoxicity, mutagenicity, carcinogenicity), as well as nuclear receptor signaling and stress response pathways. The results revealed that p-cymene exhibited the highest toxicity (LD50 = 3 mg/kg, class I), followed by oleic acid (LD50 = 48 mg/kg, class II), whereas amylbenzene was classified as non-toxic (LD50 = 6430 mg/kg, class VI). All compounds were predicted to be non-hepatotoxic and non-immunotoxic; however, p-cymene, indole, and amylbenzene showed potential carcinogenicity. Limonene was predicted to be active against AhR, ER, MMP, and ATAD5 receptors, while dieugenol was active against nrf2/ARE, HSE, and MMP. These predictions suggest that most compounds are safe for shampoo applications, except for p-cymene, which requires further evaluation. This study provides preliminary insights for the development of safe and effective natural-based shampoos.
Co-Authors . andriyanto . Soeripto Adi Winarto Afiff , Usamah Aisyah Nurfitria Ayumi Alifiana Fitrianingrum Alifin Wisnu Ananta Alpayet, Rahmat Amaq Fadholly Amperanoto, Agus Amrozi Andriyanto Andriyanto . Andriyanto . Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto, Andriyanto Andriyanto Anggia Murni Wijiati Anggraeni, Henny Endah Anggraini, Lutvi Anisa Rahma, Anisa April Hari Wardhana April Hari Wardhana April Hari Wardhana Arief Sabdo Yuwono Aurelia, Sharon Bambang Pontjo Priosoeryanto Bondan Achmadi Budi Purwanto Diah Nugrahani Pristihadi Diky Yuliansah Diky Yuliansah Dodi Darmakusuma Dodi Darmakusumah Edwin Ligia Sastra Ekowati Handharyani Elpita Tarigan Elpita Tarigan Erli Chandra Esti Dhamayanti Fadiela Salima Putri Febrita, Joana Fedik Abdul Rantam Fifi Gus Dwiyanti Firda Agustin Firda Agustin Firda Agustin, Firda Hamdika Yendri Hamdika Yendri Hamdika Yendri Hamdika Yendri Putra Hudaya, Aang IBNUL QAYIM IETJE WIENTARSIH IPB, BPKB Irarang, Yusa Jusuf, Elena Adjani Kharisma Mardathilah Kharisma Mardathilah Khonsa Khonsa Kusdiantoro Muhamad Lailan Safina Nasution Leliana Nugrahaning Widi Leliana Nugrahaning Widi Leliana Nugrahaning Widi Leliana Widi Leo Sapelani Soinbala Lina Novianti Sutardi Lina Novianti Sutardi, Lina Novianti Lina Noviyanti Sutardi M. Agung Zaim Adzkiya Madyastuti, Rini Mardathilah, Kharisma Meilisa Lidya Margarita Meti Ekayani Michella Hoseana Wijaya Mohammad Miftahurrohman Muhammad Bintang Nababan, Ratna Kristiani Nabilah, Avida Shahnaz Ni Made Ria Isriyanthi Purohita, Adwisto Saktika Putra, Hamdika Yendri Putra, Heriansyah Putri, Fadiela Salima Rahmawati Januar Rahminiwati, Min Rai Sita Rendi Pratama Mukti Ridi Arif Rifnadhi, Bayu Rina Mardiana Rindy Fazni Nengsih Rindy Fazni Nengsih Risna Anggraeni Rukmana, Adi Safitri, Nadiya Santosa, Alfian Sari, Windi Mayang Silmy Kamila Widyanti Siti Saadah SM Leluala Subangkit, Mawar Sultania A Suleman Sus Derthi Widhyari Trioso Purnawarman Unang P. Upik Kesumawati Hadi Utami, Annisa Dwi Wasmen Manalu Widi, Leliana Nugrahaning Yayuk Sri Rahayu Yendri, Hamdika Yuliansah, Diky Yusa Irarang Zaenal Abidin