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All Journal PROSIDING SEMINAR NASIONAL Indonesian Journal of Cancer Chemoprevention Indonesian Journal of Pharmaceutical Science and Technology Biomedika Pharmacon Jurnal Farmasi Indonesia PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Indonesian Community Journal Abdi Geomedisains Jurnal Farmasi Sains dan Praktis SWARNA Urecol Journal. Part C: Health Sciences Prosiding University Research Colloquium Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat Panacea Usadha Journal of Pharmacy SWARNA: Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Journal of Pharmascience
Arifah Sri Wahyuni
Universitas Muhammadiyah Surakarta
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Uji Aktivitas Antidiabetes Kombinasi Esktrak Daun Kelor (Moringa oleifera L.) dan Daun Jambu Biji (Psidium guajava) Pada Tikus Putih Jantan Galur Wistar Wahyuni, Arifah Sri; Haryati, Resti Dwi; Fadhilah , Arini
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1135

Abstract

Purpose: to test whether the combination of Moringa oleifera L. and guava (Psidium guajava) leaf extract has a better effect in reducing blood glucose levels compared to single extracts. Method: an experiment with a pre- and post-test with control group design. The samples were Moringa leaves, guava leaves with 30 Wistar rats divided into 6 groups. Normal control group, negative control group (Na CMC 1%), positive control group (glibenclamide 5 mg/kgBW), Moringa leaf extract group dose 100 mg/kgBW, guava leaf extract group dose 105 mg/kgBW, and a combination group of Moringa leaf extract with guava leaves. Data analysis used a computerized program using the Welch ANOVA and Post Hoc Games-Howell tests. Results: showed that all treatment groups significantly reduced blood glucose levels compared to negative controls (p<0.05), but the effect was not comparable to positive controls and was not significant with normal controls on day 21. The combination of EEDK and EEDJB did not provide a better effect than the single extract. Conclusion: This study shows that the single extract and the combination of moringa leaf and guava leaf extracts have antidiabetic activity, but the combination of moringa leaf and guava leaf extracts did not show a better effect.
Pengaruh Pemberian Ekstrak Etanol 50% Daun Matoa (Pometia pinnata J.R.Forst & G.Forst) Terhadap Kadar Glikogen Hati Tikus Putih Jantan Hiperglikemik Ningrum, Nur Faizah Setya; Wahyuni, Arifah Sri
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Mahasiswa (Student Paper)
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Penelitian ekstrak etanol 50% daun matoa atau EEDM (Pometiapinnata J.R.Forst & G.Forst) dengan kandungan berupa flavonoidyang memiliki aktivitas antioksidan mampu menetralkan radikalbebas dengan meregenerasi sel ? pankreas dalam memproduksihormon insulin. Penurunan kadar gula darah disebabkan karenakelebihan gula disimpan dalam bentuk glikogen dengan bantuanhormon insulin. Penelitian ini bertujuan untuk menetapkan pengaruhekstrak etanol 50% daun matoa atau EEDM (Pometia pinnataJ.R.Forst & G.Forst) terhadap kadar glikogen hati pada tikuspercobaan yang diinduksi aloksan 150 mg/kgBB. Penelitianeksperimental dilakukan dengan RAL (Rancangan Acak Lengkap)terhadap 6 kelompok perlakuan yang diberi perlakuan denganakuades tanpa induksi, akuades, glibenklamid 5 mg/kgBB, dan tigakelompok EEDM dengan dosis 50, 100, dan 200 mg/kgBB EEDMselama 14 hari. Kadar glikogen ditetapkan dengan metode antronmenggunakan hati tikus yang telah dikeringkan. Hasil dari penelitianmenunjukkan bahwa EEDM dosis 50 dan 100 mg/kgBB mampumeningkatkan kadar glikogen hati yang tidak berbeda signifikan(sama) dengan kelompok tikus kontrol positif yang diberikanglibenklamid dosis 5 mg/kgBB.
PENERAPAN TEKNOLOGI TEPAT GUNA PENGOLAHAN BAHAN BAKU CACING DAN STANDARDISASI KANDUNGANNYA Utami, Wahyu; Fauzi, Ahmad; Vitasari, Denny; Wahyuni, Arifah Sri
Prosiding University Research Colloquium Proceeding of The 19th University Research Colloquium 2024: Bidang Pengabdian Masyarakat
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Tim pengabdian Universitas Muhammadiyah Surakarta telah melakukan serangkaian kegiatan pengabdian melalui Program Pengabdian Masyarakat Penerapan Teknologi Tepat Guna (P2TTG) bekerja sama dengan CV Berkah Alam sebagai mitra pengabdian. Pengabdian ini bertujuan untuk alih teknologi dalam pengolahan bahan baku cacing dan standardisasi kandungannya untuk peningkatan kualitas produk. Program pengabdian ini dilaksanakan mulai Desember 2021 selama enam bulan. Tim melaksanakan serangkaian penelitian terkait pengolahan cacing tanah dan standardisasi kandungan proteinnya kemudian mengembangkan dan menerapkannya untuk meningkatkan efisiensi produksi dan kualitas produk. Penelitian dan pengembangan yang dilakukan meliputi optimasi ekstraksi protein dari sampel kapsul cacing, terkait dengan waktu dan suhu optimum untuk mendapatkan kandungan protein paling tinggi. Selanjutnya validasi metode analisis protein dalam sampel kapsul cacing untuk memastikan bahwa metode analisis yang digunakan valid, akurat dan teliti untuk mengukur kandungan protein dalam sampel. Selanjutnya pelatihan pengolahan bahan baku cacing yang efisien untuk mendapatkan kandungan protein yang maksimal serta standardisasi proses produksinya.
Application of Appropriate Technology for Processing Worm Raw Materials and Standardization of Their Content: Penerapan Teknologi Tepat Guna Pengolahan Bahan Baku Cacing dan Standardisasi Kandungannya Utami, Wahyu; Fauzi, Ahmad; Vitasari, Denny; Wahyuni, Arifah Sri
Prosiding University Research Colloquium Proceeding of The 18th University Research Colloquium 2023: Bidang Teknik dan Rekayasa
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

The University of Muhammadiyah Surakarta community service team has carried out a series of service activities through the Community Service Program for the Application of Appropriate Technology (P2TTG) in collaboration with CV Berkah Alam as a service partner. This service aims to transfer technology in the processing of worm raw materials and standardization of their content to improve product quality. This service program will be carried out starting December 2021 for six months. The team carried out a series of studies related to earthworm processing and standardization of protein content then developed and applied it to improve production efficiency and product quality. Research and development carried out includes optimization of protein extraction from worm capsule samples, related to the optimum time and temperature to obtain the highest protein content. Furthermore, validate the protein analysis method in the worm capsule sample to ensure that the analysis method used is valid, accurate and presice to measure the protein content in the sample. Furthermore, training on efficient processing of worm raw materials to obtain maximum protein content and standardization of the production process.
Vol 20, No 2 (2023) Wahyuni, Arifah Sri
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 2 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i2.23493

Abstract

Uji Efektivitas Antihiperurisemia Ekstrak Etanol Kencur (Kaempferia galanga L.) dan Jahe Hitam (Kaempferia parviflora) terhadap Tikus yang Diinduksi Jus Hati Ayam dan Potassium Oxonate Wikantyasning, Erindyah Retno; Wahyuni, Arifah Sri; Julianti, Tri Budi; Putri, Nastity Zhahwa Amalia; Astuti, Devi Dwi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.497

Abstract

Hyperuricemia is caused by excessive production and/or poor elimination of uric acid. Kencur (Kaempferia galanga L.) and black ginger (Kaemperia parviflora) can be utilised as antihyperurisemic alternatives because their flavonoids block xanthin oxidase (XO). The study determine the efficacy of black ginger ethanol extract (EEJH) as an in vivo antihyperuricemic agent. This research was conducted to determine the effectiveness of kencur ethanol extract (EK) dan black ginger ethanol extract (EEJH) as an antihyperuricemia in vivo. A complete random design used involving 32 mice in 8 groups. Negative control (CMC Na 0.5%); positive control (Allopurinol 10 mg/kgBW); EK and EEJH respectively 12.5; 25; and 50 mg/kgBW. Hyperurisemia was induced by chicken liver juice 4 mL/200 gBB p.o. and potassium oxonate 250 mg/kgBB i.p. UA monitoring was carried out before induction, 0, 7, and 14 days after treatment. Tukey post hoc tests and ANOVA were used to evaluate the data. The results indicate that both of EK and EEJH can reduced UA (p<0.05) however the reduction is significant with Allopurinol (P<0.05). Thus, it can be inferred that the EK and EEJH have potential for enhanced antihyperurysemic in decreasing the UA.
NARRATIVE REVIEW: AKTIVITAS ANTIDIABETES DAN KANDUNGAN SENYAWA KIMIA DARI TANAMAN PEPAYA (Carica papaya Linn.) Khairani, Kafita Salma; Wahyuni, Arifah Sri
Usadha Journal of Pharmacy Vol. 2 No. 4 (2023): November
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v2i4.178

Abstract

Pepaya (Carica papaya L.) merupakan salah satu tanaman tradisional di Indonesia yang telah banyak diteliti sebagai agen antidiabetes. Tujuan penulisan narrative review ini adalah untuk menganalisis efek antidiabetes yang dimiliki oleh tanaman pepaya (Carica papaya L.) beserta kandungan senyawa yang mempengaruhinya. Penulisan narrative review ini disusun berdasarkan artikel yang ditelusuri melalui database google scholar menggunakan kata kunci "(Carica papaya or Pepaya) and (antidiabetic or hypoglycemic) and (rat or mice)”. Kriteria inklusi yang digunakan meliputi literature primer dengan desain preclinical trial yang membahas mengenai aktivitas tanaman pepaya (Carica papaya L.) yang dapat menurunkan kadar glukosa pada hewan uji yang diinduksi aloksan atau streptozotosin, dan telah dipublikasikan dari rentang tahun 2015-2020. Berdasarkan penelusuran yang telah dilakukan, kemudian ditetapkan sebanyak 15 artikel yang telah memenuhi kriteria untuk ditinjau. Dari 15 artikel tersebut ditemukan bahwa pepaya mampu menurunkan kadar glukosa darah memalui penghambatan enzim α-glukosidase, merangsang sekresi insulin dan peningkatan sensitivitas insulin. Senyawa metabolik yang bertanggung jawab dalam mekanisme tersebut diduga termasuk dalam golongan fenolik, alkaloid, terpenoid dan saponin.
Edukasi Kesehatan tentang Penyakit Degeneratif dan Informasi Obat di Kampung Biru, Banjarmasin, Indonesia: Health Education on Degenerative Diseases and Medication Information in Kampung Biru, Banjarmasin, Indonesia Jihan, Jihan; Wahyuni, Arifah Sri; Rizakh, Faizah Siti; Lathif, Elmasrini; Safitri, Dewi; Amelia, Ratih
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 11 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i11.10319

Abstract

Degenerative diseases such as hypertension, diabetes mellitus, and hypercholesterolemia are major global health concerns with high prevalence in Indonesia, including in Kampung Biru, Banjarmasin. This community service initiative aimed to enhance public knowledge about the prevention and management of degenerative diseases, while also providing medication information through the Drug Information Service (DIS). The program involved 58 participants who underwent health screenings (blood pressure, blood glucose, cholesterol, and uric acid levels), disease-specific group education, and DIS sessions conducted by pharmacists. Results showed a 60.34% improvement in participants' knowledge, with a 98.27% satisfaction rate. Data analysis revealed a higher prevalence of these diseases among the elderly (aged 45 years and above), aligning with national epidemiological trends. The program demonstrated the effectiveness of a collaborative approach involving academics, healthcare professionals, and the community in promoting health literacy and preventive care.
Edukasi Kesehatan Kognitif dan Senam Otak Lansia Menuju Lansia Mandiri dan Bahagia pada Ibu-Ibu Penggerak PKK Desa Mliwis, Boyolali, Jawa Tengah Rahmawati, Juwita; Yulianti, Tri; Putri, Annisa Nur Lathifah Amanda; Windarti, Septiana; Fadhilah, Arini Fadhilah; Wahyuni, Arifah Sri; Sukmawati, Anita; Indrayudha, Peni; Setyadi, Gunawan; Wulandari, Febri; Imanto, Teguh; Santhyami, Santhyami
Abdi Geomedisains Vol. 6, No. 2, December 2025
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

A prevalent issue among the elderly is cognitive deterioration. Modifications in behavior and the adoption of a healthy lifestyle have been demonstrated to mitigate cognitive decline in the elderly. The objective of community service initiatives is to disseminate knowledge regarding cognitive health in the elderly and to offer brain workouts to the community, particularly targeting women who are PKK activists in Mliwis Village. This community service initiative employs an instructional methodology that incorporates PowerPoint presentations and leaflets, utilizing a one-group pre-test and post-test design. The event took place at the Posyandu Sidorejo in Mliwis Village, Boyolali. The target audience for this activity was PKK mothers in Mliwis Village, Boyolali Regency, Central Java. To measure the level of knowledge about cognitive health, a questionnaire developed by the community service team was used. This activity consisted of six stages, namely opening, pretest, education, group brain exercises, discussion, and post-test. 51 participants, comprising PKK mothers, attended this activity. The most extensive age range was 31-40 years old, with 16 (31.4%) participants, and the largest occupation was housewife, with 36 (70.6%) participants. The education and discussion activities went well. The enthusiasm of the participants also increased with the joint brain exercises. The average pretest and posttest scores were 90.26 ± 10.78 and 93.68 ± 7.50, respectively. There was a significant difference in knowledge between the pretest and post-test measurements (p = 0.034; < 0.05). It is hoped that this educational activity will help form independent and happy elderly people.
Optimasi Preparasi Sampel untuk Penetapan Kadar Protein Ekstrak Cacing Tanah (Lumbricus rubellus) Ahmad Fauzi; Wahyu Utami; Denny Vitasari; Arifah Sri Wahyuni
Journal of Pharmascience Vol. 9 No. 1 (2022): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i1.12961

Abstract

Demam tifoid merupakan salah satu penyakit yang menjangkit masyarakat Indonesia dengan 500 kasus per 100.000 penduduk dengan angka kematian mencapai 5%. Pengobatan utama demam tifoid adalah menggunakan berbagai macam antibiotik. Namun masyarakat Indonesia cenderung lebih memilih pengobatan alternatif atau tradisional. Salah satu obat tradisional demam tifoid adalah ekstrak cacing (Lumbricus rubellus) yang mempunyai kandungan protein sampai 71%. Kandungan protein sangat tergantung pada proses produksinya. Untuk itu diperlukan metode preparasi dan analisis untuk menentukan kadar protein yang bisa digunakan untuk menjamin mutu produk ekstrak cacing. Metode preparasi yang optimum  adalah dengan pemanasan pada temperatur 50°C selama 5 menit kemudian dianalisis kadar proteinnya dengan metode Lowry menggunakan spektrofotometer UV-Vis pada panjang gelombang 650,8 nm. Metode linier, akurat dan teliti dengan batas deteksi sebesar 0,18 mg/mL dan batas kuantifikasi sebesar 0,58 mg/mL. Kata Kunci: Protein, Cacing Tanah, Spektrofotometri, Metode Lowry  Typhoid fever is a disease that affects Indonesian people with 500 cases per 100,000 population with a mortality rate of 5%. The main treatment for typhoid fever is the use of various antibiotics. However, Indonesian people prefer to use alternative or traditional medicine. One of the traditional medicines for typhoid fever is earthworm (Lumbricus rubellus) extract which has a protein content of up to 71%. Protein content is highly dependent on the production process. For this reason, preparation and analysis methods are needed to determine protein levels that can be used to guarantee the quality of the worm extract products. The optimum preparation method is by heating at 50°C for 5 minutes and then the protein is analyzed using the Lowry's method using a UV-Vis spectrophotometer at wavelength of 650.8 nm. The method is linear, accurat and presice with  detection limit of 0.18 mg/mL and quantification limit of 0.58 mg/mL.
Co-Authors AA Sudharmawan, AA Abdellah, Yousra Nait El Haj Adha, Dinda Caesaria Adha, Dinda Caesaria Adha Afny Al Fath Inaszahira Afrizal Maulana Agita Dyah Ayu Kusumaningtyas Ahmad Azka Mahasin Ahmad Fauzi Ahmad Fauzi Ainur Tri Hapsari Al Fawwaz, Zulfa Kamila Alida Rahmalia Damayanti Alifia Jasmina Putri Alvita Marshanda Purnama Puteri Amalia, Nastity Zhahwa Amani, Khalisa Dhiya Ana Riolina Andi Suhendi Anggun Dwi Ayu Fandirah Anisa Dwi Parwati Anita Sukmawati Anita Sukmawati Annisa Nur Lathifah Amanda Putri Annisa Nur Lathifah Amanda Putri Ar Rafi’ Kusuma Hardila Wardoyo Putri Aria Wirabima Aria Wirabima Assyifa Putri Saffira Asti Arum Sari Astrina Dewi Ratnaningrum Astrina Dewi Ratnaningrum, Astrina Dewi Astuti, Devi Dwi Audi Ahmad Rikardi Aulia Fitri Sabilla Azis Saifudin Azizah, Rauhillah Nurul Bakar, Fazleen Izzany Abu Bakhtiar, Muhammad Berlian Putri Nur Winda Candrika, Nasha Lulut Chandrika, Nasha Lulut Cita Hanif Muflihah Cita Primada Hari Anugrahini Damayanti, Alida Rahmalia Denny Vitasari DESY KURNIAWATI Desy Kurniawati Devana Inaja Arifin Devana Inaja Arifin Dewi Safitri Dinda Mentariningrum Diski Wahyu Wijayanto Eky Wahyu Novarista Elsya Bella Putri Em Sutrisna Erindyah Retno Wikantyasning Fadhilah , Arini Fadhilah, Arini Fadhilah, Arini Fadhilah Fahmi Alief Maulana Faiza Layyana Putri Farah Salsabila Fauzi Ahmad Muda Fawwaz, Zulfa Kamila Al Firda Ayu Fadila Rahmawati Firda Novia Aurum Ghossani, Qisti Fida Gunawan Setyadi Gunawan Setyadi, Gunawan Hamimatusalma Alkautsar Haryati, Resti Dwi Haya Nabilah Utama Heni Mirawati Hidayah Karuniawati Husna Amalia Halwa Ibrohim Hanif Abdulloh Ika Retno Wulandari Ika Trisharyanti Dian Kusumowati Jessica Rosalinda Jihan Jihan, Jihan Julianti, Tri Budi Juwita Rahmawati Kafita Salma Khairani Kamila, Rossy Destriana Katarina Lulu Widyanti Khairani, Kafita Salma Kharisma Aulia Husna Kholifatus Sa’diyah Lathif, Elmasrini Lilla Prapdhani Agni Hajma Lusi Nuryanti Maharani, Yasmin Nida Maulana, Fahmi Alief Muhammad Azmi Nur Asykaruddin Muhammad Da&#039;i Muhammad Da&#039;i Muhammad Haqqi Munajat Tri Nugroho Mursalina Nanda Aurum Mutiara Nurul Fatimah Nadya Putri Adisty Nadya Tiara Putri Nandifa Azzahra Salsabila Nasywa, Nabila Luthfiana Niam, Muhammad Labib Qotrun Nibrasa, Lauda Aurynava Nida’ Nur Jannah Niken Dyaharesti Ningrum, Nur Faizah Setya Nisrina Hanun Iftadi Novita Sari Novita Sari Nur Faizah Setya Ningrum Nur Muhammad Arrizky Nurazizah, Tazkia Nurul Tri Anggraini Oksaputra, Amar Khoiri Paramita, Heldiyana Ellisia Peni Indrayudha Permata Ashfi Raihana Persada, Tashila Zahra Putri, Annisa Nur Lathifah Amanda Putri, Nastity Zhahwa Amalia Putri, Vanessa Ardelia Indira Rahmadhani, Ajeng Rahmallia, Ega Ramadhan, Muhammad Reza Ramarohasina, Mika Notahiana Ranatri Puruhita Ratih Amelia Ratsimandresy, Neciah Fahombiazana Rima Munawaroh Riza Maulana Rizakh, Faizah Siti Rizky Ainun Fitriani Rosa Sayentina Amin Rosa Sayentina Amin Rosita Melannisa Rosita Melannisa, Rosita Sabar Narimo Santhyami Sari, Aisah Kensar Nawang Wulan Septyana Dewi Kumara Setyo Nurwaini Shinta Puti Aryanti Shinta Putri Aryanti Suhaimah, Insyiroh Sukamto, Dandi Febrian Sulistyarini, Sulistyarini Suryani - Tanti Azizah Sujono Teguh Imanto Tista Ayu Fortuna Tri Yulianti Tri Yulianti, Tri Ukhtufina, Naila Najwa Utama, Haya Nabilah Wahyu Utami Widagdo, Fathin Fadhilla Wijianto, Diski Wahyu Windarti, Septiana Wulandari, Febri Yeni Mulati Yola Rizky Amalia Yuniasti, Lainisah Purna Zahidah, Fairus