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All Journal Jurnal Manajemen Terapan dan Keuangan Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Jurnal Farmasi Klinik Indonesia Indonesian Journal of Biotechnology WARTA Tajdida Biomedika Pharmacon INDONESIAN JOURNAL OF PHARMACY Jurnal SOLMA Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Al Qalam: Jurnal Ilmiah Keagamaan dan Kemasyarakatan Journal of Nutraceuticals and Herbal Medicine Indonesian Journal of Medicine MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Science Midwifery Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Ekonomi Indonesia Sasambo Journal of Pharmacy International Journal of Science and Society (IJSOC) Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Management and Digital Business Jurnal Farmasi Sains dan Praktis Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika Proceeding of International Conference Health, Science And Technology (ICOHETECH) Warta LPM JMMR (Jurnal Medicoeticolegal dan Manajemen Rumah Sakit) International Journal of Community Service Implementation Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Manajemen Dayasaing Journal of Tropical Pharmacy and Chemistry
Em Sutrisna
Universitas Muhammadiyah Surakarta
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Journal : Lumbung Farmasi : Jurnal Ilmu Kefarmasian

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Evaluasi Ketepatan Pemberian Antibiotik Empirik Pada Pasien Demam Neutropenia Akibat Kemoterapi Di RSUP Dr Kariadi Semarang Pratiwi, Mida; Sutrisna, EM
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 2, No 2 (2021): JULI
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v2i2.4873

Abstract

ABSTRAKDemam neutropenia merupakan keadaan yang ditandai dengan suhu dan angka neutrofil meningkat. Neutropenia  dapat terjadi akibat kemoterapi dan merupakan keadaan darurat yang dapat mengakibatkan infeksi serius dan harus mendapatkan terapi antibiotik empirik. Penelitian ini bertujuan untuk mengevaluasi ketepatan antibiotik empirik dengan metode gyssens pada pasien kanker yang mengalami demam neutropenia. Penelitian ini menggunakan desain penelitian cross sectional dan diambil secara prospektif di RSUP Dr Kariadi Semarang periode Juli-Oktober 2019. Kriteria inklusi pada penelitian adalah seluruh pasien kanker yang mengalami demam neutropenia dan mendapatkan antibiotik empirik. Data pasien yang diperoleh dari penelitian ini dianalisis dan akan dibandingkan dengan literatur. Hasil penelitian ini mendapatkan sebanyak 101 pasien dengan 57,4% adalah perempuan dan 42,6% laki-laki. Sedangkan untuk jenis kanker yang mengalami demam neutropenia dalam penelitian ini adalah 81,2% pasien kanker non solid dan 18,8% kanker solid. Berdasarkan diagram alir  gyssens penggunaan antibiotik empirik pada pasien demam neutropenia yang tepat pada penelitian ini adalah sebesar 74,3% dan tidak tepat sebesar 25,7%.Kata kunci : Kanker; Kemoterapi; Demam; Neutropenia; Antibiotik.ABSTRACTFebrile neutropenia is a state of apprehension with increased temperature and neutrophil count. Neutropenia can occur due to chemotherapy and emergencies that can lead to serious infections and should receive antibiotic therapy. Yhis study aims to achieve antibiotic accuracy with the gyssens method in cancer patients with febrile neutropenia. The study used a cross-sectional study design and was taken prospectively at the Hospital RSUP Dr Kariadi period July-October 2019. The inclusion criteria in the study were all patients who had febrile neutropenia and received empirical antibiotics. Patient data obtained from this study were analyzed and compared with the literature and then performed statistical analysis. The result of the study were 101 patient with 57,4% being female and 42,6% male. Meanwhile, the types of cancer that had febrile neutropenia in this study were 81,2% of non solid cancer patients and 18,8% of solid cancers. Based on the gyssens flow chart the use of empiric antibiotic in patient febrile neutropenia was 74,3% and 25,&% incorrect.Keywords : Cancer; Chemotheraphy; Febrile; Neutropenia; Antibiotic.
Co-Authors . Muhtadi . MUHTADI Abdussalam, Arrizqi Hafidh Amalinda Ayu Faroska Andi Suhendi Andi Suhendi Andi, Andi Suhendi Andriani, Betty Anika Candrasari Annissa, Yanis Nur Arifah Sri Wahyuni Aris Fitriyani Ashshiddiiq, Zaid Ziyaadatulhuda Aulia, Qurrotu A’yuni Awal Prasetyo Ayustine Winarta, Selly Baiq Nova Fajriyatun Baiq Nova Fajriyatun, Baiq Nova Darnoto , Sri Dedi Hanwar DESY KURNIAWATI Desy Kurniawati Devi Usdiana Rosyidah Diana Risanti, Erika Dodik Nursanto Dona Dewi Nirlawati Dwiariawan Tauchid Rahman Dwiariawan Tauchid Rahman, Dwiariawan Tauchid Erna Kristin Esti Dwi Widayanti Faradisa, Nida Fardhiyanti, Fardhiyanti Faroska, Amalinda Ayu Fauziana , Eni Fauziana, Eni Flora Ramona Sigit Prakoeswa Frans Saputra Gunawan, Ryan Budi Hadi, Cahyono Happy Kurnia Permatasari Hasna Zahro Iftikhonsa Ihwan Susila Iin Novita Nurhidayati Mahmuda Ika Trisharyanti Dian Kusumowati Imronudin Imronudin, Imronudin Indra Nuroso Indwiani Astuti Iwan Dwiprahasto Iwan Dwiprahasto Kelik Wardiono Khaeditama Purnama Anwar Khusnul Khotimah Kurnia Retnowati Kurnia Retnowati, Kurnia Listiana Masyita Dewi Mada Sukma Dytho Maimun, Muhammad Halim Maisje Marlyn Kuhu Maryati Maryati Maryati Maryati Masyita Dewi, Listiana Maulindar, Joni Mida Pratiwi Muchlison Anis Mufidah, Fathin Muhammad Ibrahim Muhtadi Muhtadi Muhtadi MULYOTO PANGESTU Muzakar Isa N Nurhayani Noer Safita Noer Safita Nur Mahmudah Nurcahyanti . Nurcahyanti Wahyuningtyas Nurcahyanti Wahyuningtyas, Nurcahyanti Nurfauzia, Elita Nadia Nurhaliza, Alfida Aulia Rahma Firdauzy Nurhayani Nurhayani Nurhayani nurhayani Nurhayani, N Nurjanah, Adha Nuroso, Indra Peni Indrayudha Pranesti, Rahma Pratiwi, Betty Intan Purwani Rahmi , Anggraita Nur Rahmi, Anggraita Nur Ratih Pramuningtyas Ratnaningrum, Anna Retno Sintowati - Riandini Aisyah Rima Munawaroh Rini Kuswati Rochmadina Suci Bestari Ryan Budi Gunawan Safari Wahyu Jatmiko Safita, Noer Saputra, Frans Selly Ayustine Winarta Setyowatiningsih, Lilik Siti Zulaekah Sri Darnoto Studiviani Dwi Binuko, Raafika Sukma Dytho, Mada Suprapto . Suprapto . Surati Surati Tanti Azizah Sujono Usdiana Rosyidah, Devi Vianti, Melita Febry Wahyu Jatmiko, Safari Wardiono , Kelik Wasifah, Wasifah Werdany, Kusuma Estu Widananda , Clarisa Widananda, Clarisa Widiyanto, Santo Yoseph Didik Yanis Nur Annissa Yuli Kusumawati Yuni Prastyo Kurniati Yuniar, Siska Yusuf Alam Romadhon Zahro Iftikhonsa, Hasna Zaid Ziyaadatulhuda Ashshiddiiq