Cosphiadi Irawan
Divisi Hematologi Onkologi Medik, Departemen Ilmu Penyakit Dalam, RSUPN Dr. Cipto Mangunkusumo, Fakultas Kedokteran Universitas Indonesia, Jakarta, Indonesia

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Journal : Journal of Stem Cell Research and Tissue Engineering

ADIPOSE-DERIVED STEM CELL THERAPY ON NON-COMMUNICABLE DISEASE: A SYSTEMATIC REVIEW Tandarto, Kevin; Purwoko, Reza Yuridian; Oktarina, Caroline; Jonlean, Reganedgary; Irawan, Cosphiadi; Abdullah, Murdani; Pawitan , Jeanne Adiwinata
Journal of Stem Cell Research and Tissue Engineering Vol. 7 No. 1 (2023): JOURNAL OF STEM CELL RESEARCH AND TISSUE ENGINEERING
Publisher : Stem Cell Research and Development Center, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jscrte.v7i1.40636

Abstract

The increasing number of non-communicable diseases demands practical therapy innovations, including adipose-derived stem cell application. This study aimed to analyze the effectiveness of adipose stem cell therapy on non-communicable disease patients. The method used in this study was a systematic review according to PRISMA 2020 guidelines. The database search was done on PubMed, Google Scholar, Proquest, and the EBSCO host database between 2016 and 2021. ROBINS-I tool and RoB-2 were used to assess the risk of bias in the clinical trial study. The first literature search identified a total of 2615 articles. After exclusion for some reason, 6 articles were included in this systematic review study. A total of five studies were included in this study. Based on the risk of bias assessment of the included studies, it was found that all studies had a low risk of bias in all domains. This study showed that the efficacy of adipose-derived stem cell therapy was inconsistent; however, the results were promising. In addition, the results showed that adipose-derived stem cell therapy was safe without significant side effects. Further study was needed to identify therapeutic strategies based on Evidence-based Medicine (EBM).
Co-Authors -, Shelly Abdulmuthalib Abdulmuthalib Achmad Fauzi Aditya, Robby Nur Adli, Mizanul Agus Kosasih, Agus Agus Sudiro Waspodo Ahani, Ardhi Rahman Ahmad Aulia Aldrat, Hendri Aldrat, Hendri Alida Harahap Andhika Rachman Andy William Andy William Angraeni, Sri Ardian Saputra, Ardian Aru W Sudoyo Ary H Reksodiputro, Ary H Asrinda, Indria Atmakusumah, Tubagus Djumhana Auda Aziz, Auda Barasila, Atikah Chalida C. Martin Rumende, C. Martin Chyntia Olivia Maurine Jasirwan, Chyntia Olivia Maurine Deby Deby Djumhana Atmakusumah, Djumhana E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edy Rizal Wahyudi Em Yunir, Em Endang Hardjolukito Endang Hardjolukito Endang Susalit Endang Susalit Firsyada, Fajar Harahap, Agnes S. Harryanto Reksodiputro Harryanto Reksodiputro, Harryanto Hayatun Nufus Hayatun Nufus HENDRI ALDRAT Ibrahim, Febiansyah Idrus Alwi Ika Prasetya Wijaya Ikhwan Rinaldi Ilyas, Mohammad Imelda Maria Loho, Imelda Maria INDRAYANI, LENNY Irsan Hasan Jeanne Adiwinata Pawitan Jonlean, Reganedgary Leonard Nainggolan Lia Damayanti Lianda Siregar Lim Weng Kong, Lim Weng Linda Armelia Linda Armelia Linda Lison, Linda Luhuna, Muslimah Lutfiah, Evah Lyana Lyana, Lyana Maksum Radji Maksum Radji Margaluta, Ariansah Marthino Robinson Marthino Robinson Martin, Cleopas Maruhum B.H. Marbun Maruhum Bonar HM, Maruhum Bonar Merry Wintery, Merry Muchtaruddin Mansyur Muhadi Muhadi, Muhadi Murdani Abdullah Ni Ken Ritchie, Ni Ken Nikko Darnindro Noorwati Sutandyo Nur Aditya, Robby Nurjati Chaeranie Siregar, Nurjati Chaeranie Oktarina, Caroline Ong Choon Kiat, Ong Choon Purwoko, Reza Yuridian R.R., Aditia Radiana Dhewayani Antarianto Rahmat Cahyanur Rahmat Cahyanur Rahmat Cahyanur Ralph Girson Gunarsa Rianto Setiabudy Ricci Steven, Ricci Rooshoeroe, A. G. Rudi Putranto Saskia Aziza Nursyirwan, Saskia Aziza Shelly - Soejono, C. H. Sri Inggriani, Sri Sukamto Koesnoe Tanadi, Caroline Tandarto, Kevin Teguh Santoso Tenggara, Jeffry Bela The Bin Tean, The Bin Tubagus Djumhana Atmakusumah Victor, Hildebrand Hanoch Vito Filbert Jayalie, Vito Filbert Vivian Soetikno Wijaya, Indra YAHDIANA HARAHAP Yahdiana Harahap