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All Journal Biota Journal of Tropical Biodiversity and Biotechnology Indonesian Food and Nutrition Progress JMM (Jurnal Masyarakat Mandiri) Jurdimas (Jurnal Pengabdian Kepada Masyarakat) Royal Biota PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Community Empowerment Narra J Biological Environment and Pollution Jurnal Pengabdian Pada Masyarakat Quagga: Jurnal Pendidikan dan Biologi Rumphius Pattimura Biological Journal BIOTROPIC
Fajar Sofyantoro
Departemen Biologi Tropika, Fakultas Biologi, Universitas Gadjah Mada, Yogyakarta
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Histopathological Analysis of Liver Damage in Rasbora lateristriata Fish Induced by Extract Butterfly Pea Flower (Clitoria ternatea) Pertiwi, Anggita Endar; Illiyin, Sirayya; Sadewo, Imran; Rahayu, Sekar; Rumansara, Papuani Samparisna; Podhi, Felisitas Moli; Sularsah, Sais; Adelfiani, Adelfiani; Retnoaji, Bambang; Sofyantoro, Fajar; Nuriliani, Ardaning; Wijayanti, Nastiti; Saragih, Hendry T. S. S. G.; Rohmah, Zuliyati; Widiyanto, Slamet; Empra, Desi Eka Putri; Ariesti, Wiwin; Septriani, Nur Indah
RUMPHIUS Vol 8 No 1 (2026): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

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Abstract

Butterfly pea flower (Clitoria ternatea) is an Indonesian native plant known for its medicinal properties due to its rich content of anthocyanins, flavonoids, and ternatins. Although widely recognized for its health benefits, the long-term effects of its bioactive compounds require careful evaluation. This study aimed to investigate the potential hepatotoxic effects of butterfly pea flower extract on the liver of Rasbora lateristriata fish. Fish were exposed to 0 (control), 50, 75, and 100 ppm of butterfly pea extract for four days, with four fish allocated per group. Histological markers, including necrosis, vacuolization, pyknosis, and hemorrhage, were assessed in liver tissues. Data were analyzed using the Kruskal-Wallis test and Mann-Whitney U test at a 95% confidence level. Results indicated that butterfly pea flower extract caused significant hepatic damage, with increased severity at higher concentrations. The most pronounced damage was observed at 75 ppm, suggesting an optimal dose for inducing oxidative stress. This study highlights the potential hepatotoxicity of butterfly pea flower extract in aquatic species and underscores the need for further research to evaluate its safety for therapeutic use.
Comparative Analysis of Hematological Profiles in Diabetic Mice Treated with D-Allulose and Neoagaro-Oligosaccharides Salsabila Faradisa Nuris; Wiwin Ariesti; Tri Rini Nuringtyas; Budi Saksono; Rahadian Yudo Hartantyo; Fajar Sofyantoro; Nastiti Wijayanti
Quagga: Jurnal Pendidikan dan Biologi Vol 18 No 2 (2026): QUAGGA : Jurnal Pendidikan dan Biologi
Publisher : Program Studi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25134/quagga.v18i2.504

Abstract

Diabetes mellitus is characterized by chronic hyperglycemia that induces oxidative stress and inflammation, contributing to hematological dysfunction and increased systemic risk. This study comparatively evaluated the effects of D-allulose and neoagarooligosaccharides (NAOS) on hematological parameters in BALB/c mice with type 2 diabetes induced by streptozotocin. Experimental groups consisted of control, negative control, positive control (metformin), and treatment groups receiving D-allulose (0.05, 0.1, 0.2 g/kg BW) or NAOS (100, 200, 400 mg/kg BW) orally for 28 days. Hematological assessments included red blood cell (RBC) count, erythrocyte indices (hemoglobin, hematocrit, mean corpuscular hemoglobin), leukocyte count, and lymphocyte levels. Negative controls displayed decreased RBC parameters and lymphocytes, with elevated leukocytes, indicating hematological impairment associated with hyperglycemia. D-allulose improved RBC count, hemoglobin, and MCH, while reducing leukocyte count and elevating lymphocytes, especially at lower doses. NAOS primarily enhanced erythrocyte quality by improving hemoglobin, hematocrit, and MCH, while also modulating leukocyte and lymphocyte profiles. Overall, D-allulose was more effective in restoring erythrocyte quantity, whereas NAOS contributed more prominently to erythrocyte index improvement. Both agents show potential in reducing hematological disorders associated with inflammation in diabetes cases.
PEMANFAATAN DAUN KELOR UNTUK PENINGKATAN KESEJAHTERAAN MASYARAKAT DI KULON PROGO Ganies Riza Aristya; Sophia Salsabila; Fiqiha Risydah; Sovann Amadeus; Ananda Malik Akbar; Alya Tasyarofa; Khalid Abdillah Abdurahman Yuda; Anissa Cahyadevi Dyanita; Fajar Sofyantoro
JMM (Jurnal Masyarakat Mandiri) Vol 8, No 3 (2024): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v8i3.22884

Abstract

Abstrak: Sebagian besar masyarakat Kulon Progo bekerja sebagai petani dan peternak. Padukuhan Gegunung di Kulon Progo memiliki tanah yang subur. Tanaman kelor kaya akan nutrisi, memiliki akar yang kuat, dan dapat dimanfaatkan sebagai alternatif pakan ternak. Program pengabdian masyarakat ini bertujuan untuk meningkatkan pemahaman masyarakat terkait budidaya kelor serta pemanfaatannya dalam kehidupan sehari-hari. Kelompok sasaran dan lembaga yang menjadi mitra adalah kelompok ibu-ibu PKK. Jumlah peserta yang menjadi sasaran dari program ini berjumlah sekitar 50 orang. Kegiatan pengabdian masyarakat terbagi dalam tiga tahap, yakni survei awal dan perizinan, sosialisasi dan pelatihan, serta monitoring dan evaluasi. Sosialisasi dan pelatihan dilakukan dengan pemberian materi, diskusi, dan praktek langsung serta ditutup dengan pembagian bibit tanaman kelor. Evaluasi dilakukan melalui observasi peserta, wawancara, dan pengisian angket. Melalui program pengabdian ini, masyarakat berhasil memahami manfaat penggunaan tanaman kelor dalam kehidupan sehari-hari dan sanggup untuk menanam kelor di lingkungan sekitar dengan bibit yang telah dibagikan. Abstract: The community of Kulon Progo primarily engages in farming and livestock breeding. Gegunung Village, with its fertile soil, is ideal for cultivating moringa plants, which are nutrient-rich and can serve as alternative livestock feed. Our community service team conducted an educational outreach on the cultivation and benefits of moringa to enhance local understanding and usage. The program targeted the PKK women's group, involving approximately 50 participants. It was divided into three phases: initial survey, socialization and training, and monitoring and evaluation. The socialization and training phase included educational materials, discussions, and hands-on practice, concluding with the distribution of moringa seeds. Evaluation was conducted through participant observation, interviews, and questionnaires. Through this community service program, participants gained a comprehensive understanding of the benefits of moringa plants in daily life and demonstrated the ability to cultivate moringa in their local environment using the distributed seeds.
PENCEGAHAN PERNIKAHAN DINI DAN PENINGKATAN MOTIVASI UNTUK MELANJUTKAN PENDIDIKAN KE PERGURUAN TINGGI DI MAMUJU TENGAH Ganies Riza Aristya; Habib Fadhil Assidiq; Bianca Geraldine Inez; Choerunnisa Fadila Bangun; Derryl Carmenita Evelynne Winarto; Laudza Fadlil Huda; Melani Putri Pratama; Muharahmah Afiffi; Fajar Sofyantoro
JMM (Jurnal Masyarakat Mandiri) Vol 10, No 4 (2026): Agustus
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v10i4.39709

Abstract

Abstrak: Pernikahan dini masih menjadi permasalahan sosial di Desa Tobadak, Mamuju Tengah, karena berdampak pada keberlanjutan pendidikan, kesehatan remaja, dan kualitas sumber daya manusia. Kegiatan ini bertujuan meningkatkan pemahaman siswa mengenai risiko pernikahan dini serta memotivasi siswa untuk melanjutkan pendidikan ke perguruan tinggi. Sosialisasi edukatif dilaksanakan di SMA Negeri 1 Tobadak dengan melibatkan 60 siswa kelas 10, 11, dan 12. Tahapan kegiatan meliputi observasi dan koordinasi dengan pihak sekolah, penyusunan materi, ceramah interaktif, diskusi, penggunaan media visual, serta evaluasi melalui pre-test dan post-test. Sebanyak 48 siswa mengisi instrumen evaluasi secara lengkap. Pemahaman siswa dinilai berdasarkan jumlah jawaban benar, dengan rentang skor 0–3, yaitu rendah (0–1), sedang (2), dan tinggi (3). Hasil evaluasi menunjukkan peningkatan rata-rata skor dari 1,94 menjadi 2,71, atau sekitar 40%. Peningkatan ini menunjukkan adanya pergeseran pemahaman siswa dari kategori sedang menuju tinggi setelah sosialisasi.Abstract: Early marriage remains a social problem in Tobadak Village, Central Mamuju, as it affects educational continuity, adolescent health, and human resource quality. This activity aimed to improve students’ understanding of the risks of early marriage and motivate students to pursue higher education. The educational socialization program was conducted at SMA Negeri 1 Tobadak, involving 60 students from grades 10, 11, and 12. The program included initial observation and coordination with the school, material preparation, interactive lectures, discussions, visual media, and evaluation using pre-test and post-test instruments. A total of 48 students completed both evaluation instruments. Students’ understanding was assessed based on the number of correct answers, with a score range of 0–3: low (0–1), moderate (2), and high (3). The score increased from 1.94 to 2.71, representing an improvement of approximately 40%. This increase indicates a shift in students’ understanding from the moderate category toward the high category after the socialization activity.
Co-Authors Abiyyi, Muhammad Hawi Qabus Adania, Baik Aisyah Adelfiani, Adelfiani Aeniah, Siti Allimi, Hayu Swari Almunawar, Muhammad Fikri Alya Tasyarofa Ammaru Bisandyaloka Ananda Malik Akbar Andri Frediansyah Andri Frediansyah, Andri Anissa Cahyadevi Dyanita Aphrodita, Adiva Aprilia Sufi Subiastuti Apriliyani, Tia Ardaning Nuriliani Arief Maulana Sabilillah Ariel Hananya Ariesti, Wiwin Ashfiya Hanif Hasnadewi Athira Nur Rahma Azmatun Fildzah Azzahira, Faiha Azka Bambang Retnoaji Bianca Geraldine Inez Budi Saksono Choerunnisa Fadila Bangun Chusnul Azhar Cinta Alivia Atha Dafa, Maula Haqul Derryl Carmenita Evelynne Winarto Dewi, Umi Rosita Dimas, Abimanyu Dwi Eny Djoko Setyono Dwi Sendi Priyono Empra, Desi Eka Putri Erinda Putri Dewiyanti Fadhlurrohman, Galih Dzaky Fiqiha Risydah Ganies Riza Aristya Ganies Riza Aristya Ganies Riza Aristya Gizela Aulia Agustin Habib Fadhil Assidiq Halim, Shuha Ma’muriyah Hendrix I. Kusuma Hendry Tri Sakti Saragih Hidayat, Rheina Faticha Asyamsa Himarosa, Rela Adi Illiyin, Sirayya Ishana, Aurelia Araya Isra Wahid Joko Nugroho Wahyu Karyadi Karlina, Ina Khairul Anam Khalid Abdillah Abdurahman Yuda Khoiruddin Anshori Krisdiyanto Krisdiyanto Krisdiyanto, Krisdiyanto Kusuma, Hendrix I. Lathief Al Umami Laudza Fadlil Huda Lisna Hidayati, Lisna Maharesi, Chesa Ekani Marius Rademaker Mataram, Made Bagus Auriva Mayani, Olvita Melani Putri Pratama Muhammad Ardillah Rusydan Muhammad Baihaqi Muhammad Budi Nur Rahman Muhammad Hafid Dinata Muhammada, Khusnus Syifa Muharahmah Afiffi Muliawati, Adina Mulyati Mulyati Nareta Defiani Nastiti Wijayanti Nasution, Nurlita Putri Bela Nata Dwi Annisa Nizma Nur Rachman Maulana Nurhidayah, Septika Nuringtyas, Tri R. Oktaviana, Shintia Pertiwi, Anggita Endar Podhi, Felisitas Moli Pradnya Paramita Primadian Adhi Wardana Primahesa, Alfian Prissandi, Anthera Al Firdaus Purwestri, Yekti A. Pusparini, Nur Ainun Oktavia Rademaker, Marius Rahadian Yudo Hartantyo Rahayu, Sekar Rahmi, Sri N. Ramadhani, Gilang Afif Setya Rarastoeti Pratiwi Rela Adi Himarosa Rela Adi Himarosa Rizky Nuryani Rohmah, Zuliyati Rumansara, Papuani Samparisna Sadewo, Imran Saeed, Faisal Safitri, Della Thasya Liona Salsabila Faradisa Nuris Sandro Vento Saragih, Hendry T. S. S. G. Sari, Ria Vinola Septhya Saribu, Ruth Liananda Citra Dolok Senny Helmiati Sentono, Diva N. Septriani, Nur Indah Septriani, Nur Indah Simanungkalit, Eben Ezer Slamet Raharjo Slamet Widiyanto Sophia Salsabila Sovann Amadeus Sritanjung, Opi Sudarisman Sudarisman Sukirno Sukirno Sularsah, Sais Supraitno, Murtiadi Erlan Syafei, Dio Rachmaputra Syam, Adi Mazdi Tri Rini Nuringtyas Ulfa, Siti Zakia Utami, Mia Vento, Sandro Wahyu Aristyaning Putri Wahyu Aristyaning Putri Wahyu Nursehan Wahyudi, Setyanto T. Wiwin Ariesti Woro Anindito Sri Tunjung Wulandari, Mutiara Tri Yekti Asih Purwestri Yudha, Donan S. Zusrina, Laili Mufli