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Journal : Jurnal EduHealth

Test The Activity Of Administering Ethanol Extract Cream From Gambier Leaves (Uncaria Gambir Raxb) To Accelerate The Healing Of Incision Wounds On The Surface Of The Skin Of Male Wistar Strain Rats (Rattus Norvegicus) Arif, Maria Nisaul; Amansyah , Adek; Suhartina, Suhartina
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Abstract

Wound healing, especially incisions, is still a problem in the health sector due to the many cases and treatment approaches used during globalization. This research tested whether ethanol extract cream from gambier leaves (Uncaria Gambir Raxb) could accelerate the healing of skin wounds in male Wistar rats. Pre-test and post-test with control group design were used in this laboratory experiment. In this study, the acceleration of healing was the dependent variable. Meanwhile, gambier leaf extract cream is an independent variable in the laboratory of the Faculty of Mathematics and Natural Sciences, University of North Sumatra. The research process has several stages: Rat acclimatization, Gambir Leaf Extract and Cream Formula, White Rat Incisions, Histopathological Observations, and Data Processing. SPSS 22 analyzes research data. Shapiro-Wilk determined data normality. One-way ANOVA calculated group mean differences for well-distributed data (P > 0.05). The Post Hockey (HSD) test detected significant treatment differences (P 0.05). The Kruskal-Walli test is used for irregular data. In white mice, 15% gambier leaf extract cream healed cuts better than 5% and 7.5%. However, gambier leaf extract cream 7.5% has a performance like 15%. At a concentration of 7.5%, secondary metabolite compounds from gambier leaf extract heal wounds, while low concentrations suppress bacteria, making them less effective. Thus, gambier leaf extract contains antioxidant phytochemicals that can be used as medicine.
Description of renal function in type 2 DM patients at RSU Royal Prima Medan in 2022 Anita Merry Cisca; Yosep Primus Tafonao; Suhartina, Suhartina
Jurnal EduHealth Vol. 15 No. 01 (2024): Jurnal eduHealt, Edition January - March, 2024
Publisher : Sean Institute

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Abstract

One of the chronic microvascular complications that occurs in type 2 DM patients is diabetic nephropathy, which is a condition where the kidneys experience decreased function and damage to the blood filter membrane is caused by high blood sugar levels. The aim of this study was to determine the description of kidney function in type 2 diabetes mellitus patients by looking at the glomerular filtration rate from medical record data of type 2 diabetes mellitus patients at RSU Royal Prima Medan. This type of research is descriptive observational research, the population in this study is the medical records of patients with type 2 diabetes mellitus who received treatment at RSU Royal Prima Medan in 2022 with a sample size of 34 medical records of patients with type 2 diabetes mellitus who received treatment at RSU Royal Prima Medan in 2022. 2022. Data analysis using univariate analysis. The results of the study showed that the frequency of Type 2 DM at RSU Royal Prima based on age was 5.9% of patients aged 35 - 45 years and 94.1% aged > 45 years. The frequency of Type 2 DM at RSU Royal Prima based on gender was found to be 52.9% for males and 47.1% for females. The frequency of Type 2 DM at RSU Royal Prima based on the duration of suffering from Type 2 DM was found to be 2.9% of patients with a duration of suffering < 1 year, 29.4% of patients with a duration of suffering of 1 - 5 years and patients with a duration of suffering > 5 years as many as 67.6%. Presentation of Type 2 DM Renal Function based on the age of 34 patients, the majority of GFR values were in the moderately declining GFR category for patients aged > 45 years as many as 19 (55.9%) patients. Presentation of Type 2 DM Kidney Function based on gender, the GFR value in patients based on gender of the 34 patients, the majority were in the moderately decreased GFR category in patients with female gender, 10 (29.5%) patients. Presentation of Kidney Function of Type 2 DM based on the length of time they have suffered from Type 2 DM, the GFR value in patients based on the length of time they have suffered from Type 2 DM out of 34 patients, the majority of them are in the GFR category of moderate decline in patients with a duration of suffering from DM > 5 years, 19 (55.9 %) patients.
Co-Authors A, Nita A. Sabambang, A. Sabambang Abd. Rahman Agustina Ali, Najmah Amansyah , Adek Ananda, Wahyu Anita Merry Cisca Arif, Maria Nisaul ARSYAD, Hasmita Dewi Eliyanti Astuti, Mia Puji Aswin Aswin Bahtiar Bahtiar Dahliana, Besse Dahniar Dahniar Dahniar, Daniar Deasy Siregar, Santy Dewi, Cindar DK, Taufik Eka Wati, Novi Elisabeth Elisabeth Elisabeth, Angela F. Najah, F. Najah Fahrodi, Deka U. Farida Juwita Faris Jumawan, Faris fitri setiyani dwiarti, fitri setiyani Girsang, Ermi Halifah, Syarifah Hamdanah Hamdanah Hasnani, Hasnani Herman, Arfian Alinda Hutagalung, Caroline Febrina Ibrahim, Syahrianti Ikram, Zul Indrawan Indrawan Intan Andrella Nalrirati Irma S Irma Susanti S irza Haicha Pratama Ismar, Elza Fahliza Johar Amir Kangga, Elizabeth Khatifah Khlaiq, Taufiq Dunialam Lestari Ramadhani Nasution , Sri Liena, Liena Lister, Clarissa Luwandi Suhartono M. Masdi, M. Masdi M. Mustari, M. Mustari M. Yogi Riyantama Isjoni Manalu, Angelia Tesalonika Mawarni Meldawati Artayani Meliala, Yose Marselius A.P. Misbar, Nurul Fadilah Morgan, Julian Muammar Muammar, Muammar Muhammad Erik Kurniawan Muhammad Ihsan Muhammad Irfan MUHAMMAD TAUFIK Mukhtar, Zulfikri Mulyani, Yuli Wahyu Tri Mutia, Maya Sari Napiah Nasution, Ali Nasir, Aco Nasution, Chairul Radjab Natali, Oliviti Novia Novia Nurzhafirah, Nurzhafirah Oculi Zaluchu, Sarah Oktavia, Silvin Pancarina Pardi Pardi, Pardi Purba, Amelia Salsabila Purba, Arna Fransisca Millyanti Putri, Nadya Nazimuddin Putri, Rizkiana Raisa, Daeva Mubarika Ratna Septiyanti Rauf, Eka Ubaya Taruna Renaldi, Muhammad Rizal Rezeki, Naomi Grace S, Irma Susanti Sabambang, Arif Said, Nur S. San, Kon Sari, Agustina Sari, Nini N. Sembiring , Intan Permata Sari br. Siti Nuraliah, Siti Sri Lestari Ramadhani Nasution Sri Rika Amriani. H Sujatmiko3, Cahya Sukoco, Hendro Sulistijanto, Eddy Susanti, Laila Syah, Setiawan Putra Syahputra, Ari Denggan Syarif, Nurbaiti Tamarin, Tamarin Taruna Rauf, Eka Ubaya Taufik Dunialam Khaliq Thomson Parluhutan Nadapdap, Thomson Parluhutan Todung Donald Aposan Silalahi Utami, Rahmawati Ning Widya Yanti Sihotang Wienaldi, Wienaldi Wisnaningsih, Wisnaningsih Yanti Sri Rejeki Yosep Primus Tafonao Yuli Evadianti, Yuli Zul Astri Zulkifli Zulkifli