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All Journal Majalah Kedokteran Bandung ODONTO Dental Journal E-Dimas: Jurnal Pengabdian kepada Masyarakat Sriwijaya University Learning and Education International Conference HIGEIA (Journal of Public Health Research and Development) Titian Ilmu: Jurnal Ilmiah Multi Sciences UICELL Conference Proceeding AFEBI Economic and Finance Review JURNAL PENDIDIKAN TAMBUSAI Journal of Health Sciences Jurnal Review Pendidikan dan Pengajaran (JRPP) El-Mujtama: Jurnal Pengabdian Masyarakat JURNAL MANAJEMEN AKUNTANSI (JUMSI) Nurse and Holistic Care Journal Of Human And Education (JAHE) ENJEL: English Journal of Education and Literature TELL - US JOURNAL Odonto dental journal Jurnal Pengabdian Masyarakat Bangsa JPMP El-Mujtama: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Nasional (JPN) Indonesia Indonesian Journal of Community Empowerment Journal of Learning Technology Jurnal Indonesia Mengabdi
Dwi Andriani, Dwi
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Journal : ODONTO Dental Journal

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Diagnosing an Acute Leukemia From a Necrotizing Ulcerative Gingivitis in The Oral Cavity: a Case Report Andriani, Dwi; Hermawan, Panky
Odonto : Dental Journal Vol 10, No 2 (2023): December 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.2.299-305

Abstract

Background: Necrotizing ulcerative gingivitis (NUG) is an acute onset of gingival disease, that presents as an acute, painful, and destructive ulceration and inflammation of gingival tissue. This condition is one of the oral manifestations of leukemia in addition to gingival enlargement and spontaneous bleeding, oral ulceration, petechiae, hematoma, and pale mucosa. Case Report: We reported A 50-year-old woman presented with gum swelling, pain, and easy bleeding in the lower jaw gums. The patient often experiences fatigue, spontaneous bruising, dry skin, and hair loss. Extraoral examination revealed bruises on the hand. Intraoral examination revealed swelling, erythematous and ulcerative lesion, tartar, bleeding on probing in the lingual gingiva of lower central incisor teeth, mucosa pallor, and minor petechiae were observed at the buccal mucosa region 47-48. The provisional diagnosis was NUG with suspicion of systemic disorder. Result: A complete blood count was performed which showed anemia, leukopenia, neutropenia, lymphocytosis, and thrombocytopenia. We diagnosed NUG in acute leukemia patients. Conclusion: This case demonstrates the detection of leukemia and its oral manifestations in acute leukemia patient. The patient was referred to the hematologist oncology.
Effect of hyperbaric oxygen treatment on liver hepatocyte damage in oral candidiasis immunosuppressed rats Pargaputri, Agni Febrina; Andriani, Dwi; Hartono, Mardiyanto Riski; Widowati, Kharinna
Odonto : Dental Journal Vol 9, No 2 (2022): December 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.2.319-326

Abstract

Background: Liver is an organ that performs a role in metabolism and detoxification of chemical substances. The use of immunosuppressive drugs excessively not only become predisposing factor for oral candidiasis, but also can cause damage and affect liver’s function. Hyperbaric oxygen treatment was known to preserve hepatocytes and prevent liver damage. This study was aimed to investigate the effect of hyperbaric oxygen treatment on liver hepatocyte damage in oral candidiasis immunosuppressed rats.Method: We divided fifteen Wistar rats randomly into three groups: G1 (healthy rats), G2 (immunosuppressed rats with oral candidiasis), and G3 (immunosuppressed rats with oral candidiasis given hyperbaric oxygen). The immunosuppressed condition was made by giving dexamethasone and tetracycline orally for 14 days. Induction of Candida albicans 0.1 cc was conducted on the fourth day. Hyperbaric oxygen treatment was given for five days continuously. The histopathological changes in the liver were measured by counting the amount of normal hepatocytes, pycnotic, karyolysis, karyorrhexis, and score of necrosis area using light microscope with 400x magnification.Result: The amount of pycnotic, karyolysis, and karyorrhexis hepatocytes increased in G2 and decreased significantly in G3, likewise the score of necrosis area. The statistical test using oneway Anova and LSD test showed significant differences (p<0,05) in pycnotic, karyolysis, and karyorrhexis hepatocytes between G1, G2, and G3.Conclusion: The hyperbaric oxygen treatment effect on liver hepatocyte damage in oral candidiasis immunosuppressed rats.
Co-Authors Afas, Muhammad Zainuddin Afifah, Siti Amsir, Rojani Anisatur Rofiqah, Siti Aprilia Ariestania, Vivin Arifzan Razak Arifzan Razak, Arifzan Artsiana, Sweeta Arya Brahmanta Arya Brahmanta, Arya Bambang Sucahyo Basyir, Turmudzi Bunayya, Haikal Wafi Cecep Darmawan, Cecep Damaiyanti, Ade Dian Mulawarmanti, Dian Difran Nobel Bistara Dina Yeni Martia Dwi Setianingtyas Effendi Effendi Eka Agustina, Eka Elidasari, Monika Endah Wahjuningsih, Endah Eram Tunggul Pawenang Fatimatuzzahro, Naila Fatria, Mega Fauzia, Bunga Firman, Dody Fiska Marina Fitria Rahmitasari Fitriano, Yufita Haidorizal, Rifkan Hartono, Mardiyanto Riski Henu Sumekar Hermawan, Panky Indra Irawan Indra Irawan Irmawati, Ari Rosita Kenneth Pinandhito Kharinna Widowati, Kharinna Khoironi, Emy Kristanti Parisihni Kurniawan, Hansen Kusumawardani, Chaterina Diyah Nanik Laihad, Fanny M. Lelyana, Nora Lestari, Siti Lilik Muklas, M Mustofa, M.Iqbal Muzakki, Haris Nafi'ah Nafi?ah, Nafi?ah Nafiah Ningsih, Nurtia Nora Lelyana Oktaviani, Paramita Devi Pargaputri, Agni Febrina Pargaputri, Agni Febrina Prabowo, Aviyuda Priambodo, Nur Tsurayya Puspita, Sinta Rahman, Dea Lupita Rambe, Riris Nurkholidah Ratna Ariesta Dwi Andriani Riki Renaldo, Riki Rima Parwati Sari, Rima Parwati Rinawati Rinawati Ritonga, Susi Febriani Salim Salim Saptaswari, Dianty Saptaswari, Dianty Sari, Epita Shintya Rizki Ayu Agitha Sodikin, Ahmad Sularsih Susanti Susanti Syahdinda, Meralda Rossy Syamsulina Revianti TATI NURHAYATI Thoriq, Ziqri Tsurayya, Nur Twi Agnita Cevanti Vivin Ariestania Wahjuningsih, Endah Widyasri Prananingrum Yufita Fitriani