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All Journal JURNAL KIMIA SAINS DAN APLIKASI AKADEMIKA JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Pemberdayaan Masyarakat Madani (JPMM) Jurnal Pendidikan Kimia (JPKim) Indonesian Journal of Chemistry Chemistry Indonesian Journal of Chemical Research Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia Jambura Journal of Health Sciences and Research Jambura Journal of Food Technology Jambura FIsh Processing Journal Jambura Journal of Educational Chemistry Jambura Journal of Chemistry Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Mattawang: Jurnal Pengabdian Masyarakat Lumbung Inovasi: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmaceutical Education Damhil: Jurnal Pengabdian kepada Masyarakat
Yuszda K Salimi
Universitas Negeri Gorontalo
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Screening of Secondary Metabolite Compounds of Gorontalo Traditional Medicinal Plants Using the In Silico Method as a Candidate for SARS-CoV-2 Antiviral Yuszda K. Salimi; La Ode Aman; Zaenul Wathoni; Netty Ino Ischak; Akram La Kilo; La Alio
Jurnal Kimia Sains dan Aplikasi Vol 25, No 10 (2022): Volume 25 Issue 10 Year 2022
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.25.10.382-393

Abstract

COVID-19 is a disease that caused a prolonged pandemic in many countries caused by the SARS-CoV-2 virus. This study aims to identify the antiviral potential of secondary metabolites in Gorontalo traditional medicinal plants, which are believed to have the ability to inhibit the main protease protein of this virus. The methods used in this research were molecular docking and molecular dynamic. The main protease proteins for SARS-CoV-2 used based on the homology modeling results were 3V3M and 7TE0. The results of the active compounds in the paxlovid drug were also compared to obtain accurate data comparisons. The validation of the docking method on the 3V3M protein using the natural ligand 0EN revealed an RMSD of 0.75 Å. The RMSD value for validating the 7TE0 protein and natural ligand 4WI was 1.65 Å. The best molecular docking results were obtained using physalin F with a binding affinity of −10.3 kcal/mol for the 3V3M protein and physalin J with a binding affinity of −8.9 kcal/mol for the 7TE0 protein. The outcomes of the molecular dynamic method on the best complexes were determined by examining the value of changes in system energy, changes in system temperature, changes in system pressure, RMSD, RMSF, and bond-free energy (ΔG) of the complex. The standard 0EN ligand had a ΔG of −26.53 kcal/mol, while the standard 4WI ligand had a ΔG of −47.16 kcal/mol. The ΔG of the 3V3M-physalin F and 3V3M-physalin J complexes were respectively −28.22 kcal/mol and −26.62 kcal/mol. The ΔG of the 7TE0-Vitexin 2”-O-gallate and 7TE0-physalin J complexes were found to be −28.08 kcal/mol and −26.62 kcal/mol, respectively. The ΔG produced in paxlovid with complexes 3V3M and 7TE0 was −19.38 kcal/mol and −25.44 kcal/mol, respectively. Physalin F, physalin J, and Vitexin 2”-O-gallate have great potential to become SARS-CoV-2 inhibitor agents. However, in terms of structural stability and binding-active residues, these three compounds do not outperform the active substance in paxlovid.
THE INFLUENCE OF NUTRITION SCIENCE LEARNING ON STUDENTS ON THE CONSUMPTION ATTITUDE OF TRADITIONAL GORONTALO FOOD (The Influence of Learnng Nutrition Sciences on Students to Attitudes of Gorontalo Tradisional Food Consumption) Arifasno Napu; Irwan Irwan; Hartati Inaku; Anna Y. Pomalingo; Yuszda K. Salimi; Alimuddin Alimuddin
Jambura Journal of Health Sciences and Research Vol 5, No 1 (2023): JANUARI: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v5i1.17347

Abstract

AbstrakMakanan tradisional sudah mulai kurang dikenal dan bahkan ditinggalkan oleh generasi muda termasuk di Gorontalo. Mengantisipasinya, di Gorontalo telah dilaksanakan kebijakan pelestarian dan pengembangannya melalui mata pelajaran muatan lokal (mulok) ilmu gizi berbasis makanan tradisional Gorontalo (MTG) pada pendidikan dasar (SD,SMP) dan menengah (SMA/SMK). Kebaruan dalam penelitian ini karena meneliti tentang pembelajaran Ilmu Gizi terhadap sikap konsumsi makanan traditional Gorontalo. Tujuan penelitian ini adalah  menganalisis pengaruh pembelajaran Ilmu Gizi terhadap sikap konsumsi MTG pada siswa yang menerima mata pelajaran mulok dan tidak mulok. Metode penelitian dilakukan secara purposive ditentukan contoh SMP di kabupaten/kota yang punya kesamaan letak geografi dan tingkat akreditasi. Provinsi Gorontalo punya 6 daerah kabupaten/kota sehingga contoh sekolah berjumlah 24 SMP (12 sekolah mulok dan 12 tidak mulok) dan setiap sekolah diwakili oleh 13 contoh siswa. Penentuan contoh siswa ini secara stratified random sampling karena populasi terdiri dari siswa yang mendapat mulok dan tidak mulok.Total contoh siswa dalam penelitian ini ada 305. Hasil penelitian bahwa sikap konsumsi MTG meliputi suka dengan alasan karena penampilan, tekstur, aroma khas, cita rasa, menyehatkan dan mudah diperoleh pada siswa mulok berbeda nyata dengan tidak mulok (p0,05). Kesimpulan bahwa pembelajaran mulok ilmu gizi berbasis MTG berpengaruh pada perubahan sikap contoh siswa. Kata kunci: Pembelajaran ilmu gizi; Makanan tradisional Gorontalo; Sikap konsumsi.AbstractTraditional food has begun to be less known and even abandoned by the younger generation, including in Gorontalo. Anticipating this, in Gorontalo a policy of preservation and development has been implemented through the subject of local content (mulok) of Gorontalo traditional food-based nutrition science (MTG) in primary (SD, SMP) and secondary (SMA / SMK) education. The novelty in this study is because it examines the learning of Nutrition Science towards the attitude of traditional Gorontalo food consumption. The purpose of this study was to analyze the effect of Nutrition Science learning on the attitude of MTG consumption in students who received mulok and non-mulok subjects. The research method was carried out purposively, determining the example of junior high schools in districts/cities that have similar geographical locations and accreditation levels. Gorontalo Province has 6 districts/cities so that the example schools are 24 junior high schools (12 mulok schools and 12 non-mulok) and each school is represented by 13 examples of students. The determination of this student example is stratified random sampling because the population consists of students who get mulok and not mulok. The total number of examples of students in the study was 305. The results of the study that the attitude of MTG consumption includes liking with the reason because the appearance, texture, distinctive aroma, taste, healthy and easy to obtain in mulok students are significantly different from not mulok (p0.05). The conclusion that mtg-based nutrition science mulok learning has an effect on changing the attitudes of student examples.Keywords: Nutrition science learning; Gorontalo traditional food; Consumption attitude.
Evaluation of the Antiplasmodial Properties of Andrographis paniculata (Burm.f.) and Peperomia pellucida (L.) Kunth Nurhayati Bialangi; Mohamad Adam Mustapa; Yuszda Salimi; Weny Musa; Ari Widiyantoro; Agus Malik Ibrahim; Boima Situmeang; Julinton Sianturi
Indonesian Journal of Chemistry Vol 23, No 1 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.74481

Abstract

Plasmodium species are the infectious agents that are responsible for malaria, a disease that claims the lives of approximately 400,000 people annually. The fact that drug resistance against malaria is on the rise suggests that new antimalarial compounds need to be discovered. It is well known that medicinal plants present the best opportunity for the identification of novel antimalaria chemicals. Both the Andrographis paniculata (Burm.f.) and Peperomia pellucida (L. Kunth) species have been tested for their antiplasmodial ability against the Plasmodium falciparum strain. The P. pellucida (L. Kunth) species has also been subjected to in vitro and in vivo biological research. P. pellucida was used to isolate the steroid known as 3-hydroxy-24-ethyl-5,22-cholestadiene (1) and the triterpenoid known as 3-hydroxy-9-lanosta-7,24E-dien-26-oic acid (2). Both compounds were then tested for their activity in vitro. In the mice model, triterpenoid 2 had a substantial chemo-suppressive impact.
Identifikasi Kemampuan Kognitif Siswa pada Materi Koloid Opir Rumape; Sasmita Pomuato; Erni Mohamad; Netty Ino Ischak; Yuszda K. Salimi; Haris Munandar; Najmah Najmah
Jambura Journal of Educational Chemistry Vol 5, No 1 (2023): Februari
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jjec.v5i1.13215

Abstract

Penelitian ini bertujuan untuk mengetahui bagaiman kemampuan kongnitif siswa pada koloid di MAN I Kota Gorontalo. Penelitian/; yang dilakukan adalah kualitatif dengan jenis penelitian deskriftif. Instrumen penelitian yang digunakan dalah pilihan ganda tidak beralasan. Subjek penlitian yang digunakan adalah kelas XI IPA MAN I Kota Gorontalo dengan jumlah sampel sebanyak 31 siswa. Data dipoeroleh dari jawaban siswa pada soal pilihan ganda tidak beralasan. Data tersebut diolah berdasarkan jawaban yang kemudian dikelompokkan berdasarkan 4 indikator, setiap indikator1-3 terdiri dari 4 nomor soal dan indikator 4 terdiri dari 3 nomor soal. Hasil penelitian yang diperoleh yaitu kemampuan kongnitif siswa pada “sangat baik” dengan nilai presentasi keseluruhan 83,76% dilihat berdasarkan tabel presentasi kemampuan kongnitif. Pada indikator satu kemampuan kongniti siswa 94,35% kategori “sangat baik”, indikator 2 kemampuan kongnitif siswa 79,84% kategori “baik”, indikator 3 kemampuan kongnitif siwa 78,23% kategori “baik” dan terakhir indikator 4 kemampuan kongnitif siswa 82, 80% kategori “sangat baik”.
Identifikasi Miskonsepsi Ikatan Kimia Menggunakan Diagnostic Test Multiple Choice Berbantuan Certainty of Response Index Fadila Karim; Netty Ino Ischak; Erni Mohamad; La Ode Aman; Yuszda K. Salimi
Jambura Journal of Educational Chemistry Vol 4, No 1 (2022): Februari
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jjec.v4i1.13239

Abstract

Penelitian ini bertujuan untuk mengidentifikasi miskonsepsi siswa SMA Negeri 1 Kabila pada materi ikatan kimia dengan menggunakan instrumen Diagnostic test multiple choice berbantuan Certainty of response index. Metode penelitian yang dilakukan adalah kualitatif dengan jenis penelitian deskriptif. Instrumen yang digunakan adalah Three-tier multiple choice. Subjek penelitian yang digunakan adalah kelas XI IPA SMA Negeri 1 Kabila dengan jumlah sampel sebanyak 58 siswa. Data penelitian ini di peroleh dari jawaban siswa pada soal three-tier multiple choice dan diolah berdasarkan pola jawaban siswa yang kemudian di kelompokan ke dalam kategori paham konsep , miskonsepsi error 1, miskonsepsi error 2, miskonsepsi error 3 dan tidak paham konsep. Hasil penelitian menunjukan bahwa kategori miskonsepsi error 1 (MK1) 3,22%, miskonsepsi error 2 (MK2) 8,55%, dan kategori miskonsepsi error 3 (MK3) 19,34%. Sedangkan paham konsep 12,55% dan tidak paham konsep 56,32%.
Deskripsi Kemampuan Kognitif Siswa pada Materi Struktur Atom Netty Ino Ischak; Siti Afdianti Domu; Deasy Natalia Botutihe; Yuszda K. Salimi; Opir Rumape; La Ode Aman; Najmah Najmah
Jambura Journal of Educational Chemistry Vol 5, No 2 (2023): Agustus
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jjec.v5i2.12832

Abstract

This research aims to determine the cognitive abilities of students in atomic structure material at SMA Negeri 1 Kabila. This research is descriptive qualitative research. This research was conducted at SMA Negeri 1 Kabila with a research sample of 66 students. Data collection uses instruments in the form of a two-tier multiple choice test. Research describing the cognitive abilities of students at SMA Negeri 1 Kabila on atomic structure material. The percentage of students' cognitive aspect abilities in the high category was (36%), in the medium category was (39%), and in the low category was (31%).
Sociotechnopreneurship As An Alternative For Community Empowerment In Improving The Economy Of Sugar Palm Farmers In Lonuo Village Gorontalo Province Hasanuddin; Herinda Mardin; Hapsawati Taan; Yuszda K. Salimi; Rahmatia
Mattawang: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023)
Publisher : Yayasan Ahmar Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35877/454RI.mattawang2084

Abstract

economic perspective which can become the main livelihood of the Lonuo village community so that the bioethanol center is a solution to this problem, because the production results can be used to make alcohol which is used for the cosmetics industry. , medicines The method of implementing this program is mentoring through social education activities aimed at providing social strengthening for the sugar palm farming community by providing social motivation Sociotechnopreneurship. Sociotechnopreneurship social motivation activities provide knowledge and insight to the people of Lonuo village to carry out entrepreneurship in turning palm sap into bioethanol products with the awareness that challenges need to be faced by developing ideas, having the ability to create something new, and even being able to escape from the habit of making palm sap into minimum illegal products are prohibited. Through this activity, there was an increase in the insight of the palm farmer participants regarding socio-technopreneurship in managing palm sap.
Ekstraksi, Analisis Kuantitatif dan Bioaktivitas Virgin Coconut Oil (VCO) Salimi, Yuszda K; Syarbin, Ruslun A. R.; Yusuf, Novalita; Paputungan, Mardjan; Mohamad, Erni
Jambura Journal of Chemistry Vol 5, No 1 (2023): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jambchem.v5i1.21713

Abstract

Penelitian ini bertujuan untuk mengekstraksi Virgin Coconut Oil (VCO) dengan metode CEVCO (Cold Extaction Virgin Coconut Oil), FEVCO (Fermentation Extraction Virgin Coconut Oil), IEVCO (Inducement Extraction Virgin Coconut Oil), PEVCO (Papaya Extraction Virgin Cococnut Oil) dan NEVCO (Nanas Extraction Virgin Cococnut Oil). Pengujian kualitas berbagai metode ekstraksi VCO secara kuantitatif dianalisis sifat fisikokimia, analisis komposisi asam lemak dengan Kromatografi gas – spektrofotometri Massa (GC-MS), bioaktivitas daya hambat bakteri dengan metode difusi sumuran dan bioaktivitas antioksidan dengan metode diphenil pikril hidrazil (DPPH). Hasil penelitian ini menunjukkan bahwa perlakuan terbaik pada uji fisikokimia dengan metode CEVCO (kadar air 0,0044, asam lemak bebas 0,0029, bilangan peroksida 0,0012, bilangan iod 6,4719, bilangan penyabunan 255,25 dan pH 6) dan metode FEVCO, IEVCO memenuhi syarat standar nasional Indonesia (SNI). Hasil analisis komposisi asam lemak yang terbaik pada metode IEVCO yaitu terdapat asam laurat, asam palmitat, asam kaproat, asam kaprilat dan asam kaprat. Hasil pengujian organoleptik pada metode CEVCO memiliki kualitas yang terbaik dari segi warna, rasa dan aroma. Hasil pengujian daya hambat terhadap bakteri S. aureus sebesar (15,64) dan bakteri E. coli (15,90) pada metode IEVCO dengan konsentrasi 33,33% dan lama waktu 3 jam. Hasil pengujian bioaktivitas antioksidan metode NEVCO memiliki nilai IC50 45 dengan kategori aktivitas antioksidan sangat kuat.
Identifikasi Senyawa Metabolit Sekunder Ekstrak Metanol Batang Katang-katang (Ipomoea Pes-Caprae) dan Uji Aktivitas Antioksidan Salimi, Yuszda K; R Tulie, Wina Zulviana; Bialangi, Nurhayati; Ischak, Netty Ino
Jambura Journal of Chemistry Vol 6, No 1 (2024): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jambchem.v6i1.17493

Abstract

Ipomoea pes-caprae merupakan obat tradisional yang termasuk dalam family Convollvulaceae. Tujuan penelitian ini adalah untuk mengetahui kandungan senyawa metabolit sekunder dan aktivitas antioksidan pada ekstrak Ipomoea pes-caprae. Batang Ipomoea pes-caprae diekstraksi menggunakan metode maserasi dan dilakukan uji fitokimia. Hasil fitokimia ekstrak metanol menunjukkan adanya senyawa flavonoid, tanin, dan steroid. Hasil penelitian menunjukkan bahwa isolat yang diperoleh dari Ipomoea pes-caprae berupa kristal amorf. Hasil fitokimia isolat positif mengandung senyawa flavonoid hal ini didukung dengan hasil identifikasi senyawa menggunakan spektrofotometri UV-Vis menghasilkan pita I dan II masing-masing dengan panjang gelombang 257 nm 274 nm. Spektrum IR menghasilkan gugus fungsi ulur O-H pada daerah bilangan gelombang 3195 cm-1. Uluran C-H pada daerah bilangan gelombang 2922 cm-1 dan 2851 cm-1. Uluran C=O muncul pada daerah bilangan gelombang 1716 cm-1. Tekuk C-C streching pada daerah bilangan gelombang 1459 cm-1. Hasil UV-Vis dan IR diduga isolat adalah senyawa flavonoid. Aktivitas antioksidan dengan menggunakan metode DPPH (1,1-difenil-2-pikrilhidrazil) menunjukkan bahwa ekstrak metanol menunjukkan nilai IC50 sebesar 302,85 ppm yang tergolong dalam kategori lemah.
Education to Strengthen the Economy of the Utilization of Aren Nira Producing Bioetanol in Lonuo Village, Bone Bolango District Hasanuddin; Taan, Hapsawati; Mardin, Herinda; Salimi, Yuszda K.; Rahmatia; Arafat, Muhammad Yasser; Larosa, Esta; Rasyid, Abdul; Ashari, Sri Ayu
Jurnal Pemberdayaan Masyarakat Madani (JPMM) Vol. 8 No. 1 (2024): Jurnal Pemberdayaan Masyarakat Madani (JPMM) (DOAJ & SINTA 3 Indexed)
Publisher : Fakultas Ekonomi dan Bisnis Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JPMM.008.1.03

Abstract

This economic education activity for palm sap farmers aims to provide economic strengthening and build awareness among the public, especially palm sap farmers, that palm sap water can be utilized and made into several products with high economic value, for example bioethanol products. Apart from that, it can also minimize the negative impact of the production of alcoholic drinks made from palm sap in Lonuo village. This activity uses educational methods, socialization and community assistance for sugar palm sap farmers. Empowering sugar palm farmers through product diversification is the key to increasing the quality and quantity of sugar palm sap products into various marketable products such as bioethanol. This economic education activity for palm sap farmers has had a positive impact and response from the Lonuo village community. This can be seen from the enthusiasm of the community in participating in activities at the village office. The community received education well and smoothly and increased public understanding regarding the use of palm sap into products of high economic value such as bioethanol.
Co-Authors Abdul Rasyid Abidin, Khoirul Agus Malik Ibrahim Ahmad, Halid S. Akram La Kilo Alimuddin Alimuddin Alwi S. Hasan Anna Y. Pomalingo Arafat, Muhammad Yasser Ari Widiantoro Ari Widiyantoro Arifasno Napu Arviani Arviani Astin Lukum Astin Lukum Boima Ramses Situmeang Boima Situmeang Bumulo, Nuraini Citron S Payu Deasy N Botutihe Deasy Natalia Botutihe Delvi Suleman Djalil, Jhodi Pratama Erni Mohamad Fadila Karim Hapsawati Taan Haris Munandar Hartati Inaku Hasanuddin Hasanuddin Hendri Iyabu Herinda Mardin Ibrahim, Yusni Irwan irwan Ishak Isa Jafar La Kilo Jhodi Pratama Djalil Julhim S Tangio Julinton Sianturi Jumarni Kamarudin La Alio La Ode Aman Lanto Ningrayati Amali Larosa, Esta Lisna Ahmad Lukman A. R. Laliyo Mangara Sihaloho Mardjan Paputungan Masrid Pikoli Melizubaida Mahmud Moh Adam Mustapa Moh Izwarto Piyohu Moh. Karmin Baruadi Mohamad Adam Mustapa Mohammad Zubair Hippy Murniati . Muti, Nurfadila Najmah Najmah Najmah Najmah Netty I Ischak Netty Ino Ischak Nita Suleman Novianti, Rani Nurhayati Bialangi Nurkhaliq, Nurkhaliq Opir Rumape Opir Rumape Parulian, Boima Ramses Podungge, Muhamad Ramdhan R Tulie, Wina Zulviana Rahmatia Rahmatia Rahmiyati Kasim Saiman Saiman Sasmita Pomuato Siti Afdianti Domu Siti Aisa Liputo Siti Rahmatia Machieu Sri Ayu Ashari Sriwanda Van Solang Sriyanti S Said Suleman Duengo Sunarty Suly Eraku Suryanto Suryanto Syarbin, Ruslun A. R. Tahir, Wawan Umar Sako, Umar Weny J.A Musa Weny Musa Widy Susanti Abdulkadir Wisna Taniyo Wiwin Rewini Kunusa Yayurulia Hadju Yoyanda Bait Yuliyanti Kadir Yusni Ibrahim Yusuf, Novalita Zaenul Wathoni