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HUBUNGAN ANTARA DERAJAT KEPARAHAN STROKE DENGAN KEJADIAN STROKE-ASSOCIATED PNEUMONIA Wandira, Rega Dwi; Amalia, Lisda; Fuadi, Iwan
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 35 No 2 (2018)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v35i2.20

Abstract

ASSOCIATION BETWEEN STROKE SEVERITY AND STROKE-ASSOCIATED PNEUMONIAABSTRACTIntroduction: Stroke-associated pneumonia (SAP) occurs in 5-26% and decreases the quality of life and clinical outcomes of stroke patients. One of the factors that affect the incidence of SAP is the stroke severity.Aims: To determine the association between the stroke severity and the incidence of stroke-associated pneumonia in the neurological ward of Dr. Hasan Sadikin Hospital, Bandung.Methods: This is an analytic retrospective (historical) cohort design study. The study population was stroke patients who were treated in the neurological ward of Dr. Hasan Sadikin Hospital, Bandung between 2014-2016. Exclusion criteria were patient with pneumonia other than SAP and using mechanical ventilation. Stroke severity was assessed using NIHSS (National Institute of Health Stroke Scale). Chi-square was used to determine inter-variable association.Results: Among 81 subjects, 24 were assessed as SAP (29.6%). The SAP prevalence were mostly male (58.3%), age group between 65-74 year old (41.7%) with hypertension risk (87.5%), stroke onset <48 hours, lesion location on left hemisphere, onset of SAP≥48 hours, and those with consciousness impairment. Those with high stroke severity tend to have higher risk of pneumonia 3.063 times compare to patients with low stroke severity.Discussion: There was a significant association between the severity of stroke and the incidence of SAP in the neu- rological ward of Dr. Hasan Sadikin Hospital, Bandung.Keywords: NIHSS, stroke-associated pneumonia, stroke severityABSTRAKPendahuluan: Stroke-associated pneumonia (SAP) cukup sering terjadi (5-26%) pada pasien stroke, sehingga menurunkan angka kualitas hidup dan luaran klinis. Salah satu faktor yang memengaruhi kejadian SAP adalah derajat keparahan stroke.Tujuan: Mengetahui hubungan antara derajat keparahan stroke dengan kejadian SAP di Ruang Rawat NeurologiRSUP Dr. Hasan Sadikin, Bandung.Metode: Penelitian analitik dengan desain kohort retrospektif (historikal) terhadap pasien stroke iskemik yang di rawat di Ruang Rawat Neurologi RSUP Dr. Hasan Sadikin, Bandung pada tahun 2014-2016. Kriteria eksklusi adalah pasien dengan pneumonia selain SAP dan menggunakan alat ventilasi mekanik. Derajat keparahan stroke dinilai menggu- nakan skor NIHSS (National Institutes of Health Stroke Scale). Uji korelasi Chi-square digunakan untuk melihat hubungan antar-variabel.Hasil: Didapatkan 81 subjek yang 24 orang di antaranya  mengalami SAP (29,6%). Prevalensi SAP tertinggi pada laki-laki (58,3%) kelompok usia 65-74 tahun (41,7%) dengan faktor risiko hipertensi (87,5%), onset stroke<48 jam, lokasi lesi di hemisfer kiri, onset SAP≥48 jam, serta pada subjek dengan penurunan kesadaran. Subjek dengan derajat keparahan stroke berat memiliki risiko terjadinya pneumonia 3,063 lebih tinggi dibandingkan dengan derajat keparahan ringan.Diskusi: Terdapat hubungan yang bermakna antara derajat keparahan stroke dengan kejadian SAP di Ruang Rawat Neurologi RSUP Dr. Hasan Sadikin, Bandung.Kata kunci: Derajat keparahan stroke, NIHSS, stroke-associated pneumonia
HUBUNGAN ANTARA DERAJAT KEPARAHAN STROKE DENGAN KEJADIAN STROKE-ASSOCIATED PNEUMONIA Wandira, Rega Dwi; Amalia, Lisda; Fuadi, Iwan
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 35 No 2 (2018)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v35i2.20

Abstract

ASSOCIATION BETWEEN STROKE SEVERITY AND STROKE-ASSOCIATED PNEUMONIAABSTRACTIntroduction: Stroke-associated pneumonia (SAP) occurs in 5-26% and decreases the quality of life and clinical outcomes of stroke patients. One of the factors that affect the incidence of SAP is the stroke severity.Aims: To determine the association between the stroke severity and the incidence of stroke-associated pneumonia in the neurological ward of Dr. Hasan Sadikin Hospital, Bandung.Methods: This is an analytic retrospective (historical) cohort design study. The study population was stroke patients who were treated in the neurological ward of Dr. Hasan Sadikin Hospital, Bandung between 2014-2016. Exclusion criteria were patient with pneumonia other than SAP and using mechanical ventilation. Stroke severity was assessed using NIHSS (National Institute of Health Stroke Scale). Chi-square was used to determine inter-variable association.Results: Among 81 subjects, 24 were assessed as SAP (29.6%). The SAP prevalence were mostly male (58.3%), age group between 65-74 year old (41.7%) with hypertension risk (87.5%), stroke onset <48 hours, lesion location on left hemisphere, onset of SAP≥48 hours, and those with consciousness impairment. Those with high stroke severity tend to have higher risk of pneumonia 3.063 times compare to patients with low stroke severity.Discussion: There was a significant association between the severity of stroke and the incidence of SAP in the neu- rological ward of Dr. Hasan Sadikin Hospital, Bandung.Keywords: NIHSS, stroke-associated pneumonia, stroke severityABSTRAKPendahuluan: Stroke-associated pneumonia (SAP) cukup sering terjadi (5-26%) pada pasien stroke, sehingga menurunkan angka kualitas hidup dan luaran klinis. Salah satu faktor yang memengaruhi kejadian SAP adalah derajat keparahan stroke.Tujuan: Mengetahui hubungan antara derajat keparahan stroke dengan kejadian SAP di Ruang Rawat NeurologiRSUP Dr. Hasan Sadikin, Bandung.Metode: Penelitian analitik dengan desain kohort retrospektif (historikal) terhadap pasien stroke iskemik yang di rawat di Ruang Rawat Neurologi RSUP Dr. Hasan Sadikin, Bandung pada tahun 2014-2016. Kriteria eksklusi adalah pasien dengan pneumonia selain SAP dan menggunakan alat ventilasi mekanik. Derajat keparahan stroke dinilai menggu- nakan skor NIHSS (National Institutes of Health Stroke Scale). Uji korelasi Chi-square digunakan untuk melihat hubungan antar-variabel.Hasil: Didapatkan 81 subjek yang 24 orang di antaranya  mengalami SAP (29,6%). Prevalensi SAP tertinggi pada laki-laki (58,3%) kelompok usia 65-74 tahun (41,7%) dengan faktor risiko hipertensi (87,5%), onset stroke<48 jam, lokasi lesi di hemisfer kiri, onset SAP≥48 jam, serta pada subjek dengan penurunan kesadaran. Subjek dengan derajat keparahan stroke berat memiliki risiko terjadinya pneumonia 3,063 lebih tinggi dibandingkan dengan derajat keparahan ringan.Diskusi: Terdapat hubungan yang bermakna antara derajat keparahan stroke dengan kejadian SAP di Ruang Rawat Neurologi RSUP Dr. Hasan Sadikin, Bandung.Kata kunci: Derajat keparahan stroke, NIHSS, stroke-associated pneumonia
Inactivated SARSCoV2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report Amalia, Lisda
Jurnal Neuroanestesi Indonesia Vol 14, No 1 (2025)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v14i1.631

Abstract

Introduction: Global pandemic of Coronavirus disease 2019 (COVID-19) have been developed with a respiratory infection as main symptom and vaccines had been proven against SARS-CoV-2 infection. We would like to present acute transverse myelitis with hypercoagulable condition case, after receiving the inactive SARS-CoV-2 vaccine (SinoVac). Case Presentation: This is a case from a 20-year-old male with acute onset of flaccid paraplegia, hyporeflexia, loss of sensation below 5th thoracic level, loss of autonomic function, and a positive Babinski sign bilaterally on 7 days after receiving SARS-CoV-2 vaccine. From lumbar puncture examination, we found elevated liquor cerebrospinal protein with mononuclear cell predominantly and elevated d-dimer and also decreased fibrinogen levels from laboratory examination. From Magnetic Resonance Imaging (MRI) showed hyperintensity at the 5th until 9th thoracal level. He improved motoric strength of the lower limb (walking without assistance), numbness and pain, urine and fecal retention after receiving methylprednisolone for 3 days. Conclusion: Acute transverse myelitis with hypercoagulable state was a rare case associated with COVID-19 vaccination, but clinician should be aware for early detection and giving proper treatment.
Characteristics of Cardioembolic Stroke Patient in Neurologic Ward Dr. Hasan Sadikin General Hospital Bandung Adriana Damayanti; Lisda Amalia; Reza W. Sudjud
Journal of Medicine and Health Vol 2 No 1 (2018)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v2i1.740

Abstract

Stroke is the second most common cause of death worldwide after heart disease. About80% stroke cases are ischemic stroke. One of 4 people with ischemic stroke had cardioembolicstroke. Ninety percent of cardiac emboli obstruct cerebral blood vessels and causedneurological deficit. Cardioembolic stroke may be due to abnormalities in cardiac walls,rhythm, valve, or function. Stroke patients with cardiac abnormalities have poor prognosis. Thisretrospective descriptive study was done in May-June 2017. We collected 103 medical recordsof stroke patients from Department of Neurology, Dr. Hasan Sadikin General Hospital duringJanuary 2015- March 2016. Data regarding sex, age, education level, economic status, andcardiac abnormalities were recorded. Majority of subjects were female (53.4%). The mostfrequent age group was 45-65 years old (49.51%). Most subjects had low educational level(76.7%) and low economic status (77.67%). Among subjects, 41.75% had cardiac rhythmabnormalities, 29.13% had cardiac wall abnormalities, 14.56% had cardiac valveabnormalities, and 14.56% had cardiac function abnormalities. The most common cause ofcardioembolic stroke was atrial fibrillation.Keywords: cardioembolic stroke epidemiology, patient characteristics, cardiac disease
Clinical Profile of Stroke Patients with Vertigo in Hasan Sadikin General Hospital Bandung Neurology Ward Amany Khansa; Aih Cahyani; Lisda Amalia
Journal of Medicine and Health Vol 2 No 3 (2019)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v2i3.1225

Abstract

Vertigo often occurs from the ages of 18 to 79 years with a prevalence of 7.4%. Central vertigo is less common than peripheral vertigo, but it can worsen disability in stroke patients. This study aims to determine the profile of stroke patients with vertigo in Hasan Sadikin General Hospital Bandung Neurology Ward. This is a retrospective descriptive study, using medical record data from 2013 to 2017, and collected 173 medical record data. The results showed that most stroke patients with vertigo were women (59%), the most age group was 55-64 years (34.1%), the most common type of stroke was ischemic stroke (75.7%), the most disturbance regarding the vertebrobasilar system was (72.8%), the most patients got the first stroke was (52.6%), 60.7% of patients suffered from hypertension, 23.1% of patients suffered from hyperlipidemia 40 (23.1%), and 22% of patients suffered from diabetes mellitus type 2. This study concludes that stroke patients who experience vertigo are more common in women, and in the 55-64 year age group. The most common stroke is ischemic in the vertebrobasilar system. Most symptoms in stroke patients with vertigo are dizziness not affected by position, vomiting and nystagmus. Hypertension, hyperlipidemia and diabetes mellitus play an important role in the incidence of stroke in patients. Keywords: vertigo, risk factor, stroke, vertebrobasilar
Dexmedetomidine as an Adjunct in Anesthesia for Adolescent Idiopathic Scoliosis (AIS) Surgery: A Case Series Nofiyanto, Eko; Halimi, Radian Ahmad; Fuadi, Iwan; Abdul rachman, Iwan
Jurnal Neuroanestesi Indonesia Vol 14, No 2 (2025)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v14i2.682

Abstract

Scoliosis is a spinal curvature deformity 10, with Adolescent Idiopathic Scoliosis (AIS) affecting those aged 10-18 years. The global prevalence of AIS is between 1%-2%, while in Indonesia, it stands at 2,93%, with a female-to-male ratio of 4.7:1. Perioperative challenges include nerve damage, bleeding, and postoperative pain. Neuromonitoring (MEP and SSEP) helps prevent injury, while careful drug selection supports spinal protection. Three female patients scoliosis reconstructions were performed under general anesthesia. All received target- controlled infusion (TCI) propofol, dexmedetomidine, and fentanyl, with stable hemodynamics and no neurological changes post-surgery. Epidemiological data showed that AIS predominantly affects females. The study included patients with curve progression impacting activity, with no motor or sensory abnormalities observed. Anesthesia was induced with propofol TCI (4 ?g/mL) and dexmedetomidine (0.3-0.7 mcg/kg/hr), reducing propofol and opioid use. Dexmedetomidine targets ?2-adrenergic receptors, reducing sympathetic outflow, stabilizing hemodynamics, blocking pain transmission, and improving recovery by reducing blood loss and inflammation. Dexmedetomidine provides sedation, analgesia, and stable hemodynamics in scoliosis surgery, minimizing blood loss and transfusion needs. It supports neurophysiological monitoring, reduces postoperative pain, and enhances recovery.
Correlation between Acute Phase Symptoms with Neurological Long Covid Symptoms on COVID-19 Survivors Ganiem, Ahmad Rizal; Siuliyanty, Siuliyanty; Ong, Anam; Gamayani, Uni; Amalia, Lisda; Wibisono, Yusuf
International Journal of Integrated Health Sciences Vol 11, No 2 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v11n2.3215

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Objective: To investigate prolonged neurological impacts of COVID-19 and establish a connection between initial COVID-19 symptom severity and chronic fatigue syndrome (CFS) development, poor sleep quality (PSQ), and cognitive impairment (CI) in individuals recovered from COVID-19.Methods:  This cross-sectional study recruited COVID-19 survivors at Dr. Hasan Sadikin General Hospital Bandung, Indonesia, between June and December 2021. All participants gave informed consent and underwent interviews on demography, clinical features, long-COVID questionnaire, and neurological examination. Participants underwent cognitive examination (MOCA-INA), Chalder Fatigue Scale and Pittsburgh Sleep Quality Index (PSQI) to assess CI, CFS, and PSQ variables. Chi-Square analysis was performed to determine the probability of neurological long COVID-19 syndrome manifestations using SPSS 24.0.Results: Of the 127 participants recruited, 67.7% were women, median (IQR) age of 33 (21-65) years, and time from hospitalization to examination of nine months (1-13). The most common neurological Long COVID symptoms were PSQ (59.8. %), CFS (51.2%), and CI (33.9%). Participants with more than five acute phase COVID-19 symptoms had a higher probability of CFS and CI (OR 2.38 (1, 16-4.9, CI 95%); OR 2.20 (1.01-4.79, CI 95%)) than those with less than five symptoms. The study did not find a significant correlation between sleep quality and number of acute-phase COVID-19 symptoms (OR 1.56 (0.76-3.20, CI 95%)).Conclusion: Almost two-thirds of the COVID-19 survivors experienced PSQ, more than half had CFS, and almost one-third had CI. The study revealed an increasing likelihood of CFS and CI in COVID-19 survivors as the number of acute COVID-19 symptoms increases.
Tatalaksana Anestesi pada Pasien Anak dengan Cystic Craniopharyngioma yang Menjalani Gamma Knife Radiosurgery Widiastuti, Monika -; Halimi, Radian Ahmad; Fuadi, Iwan; Rahardjo, Sri; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 10, No 2 (2021)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3082.611 KB) | DOI: 10.24244/jni.v10i2.353

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Kraniofaringioma merupakan tumor otak jinak dengan karakteristik kistik dan kalsifikasi, yang letaknya dikeliingi oleh stuktur vital sehingga sulit untuk dilakukan reseksi total. Terapi kombinasi dengan Gamma knife radiosurgery (GKRS) merupakan pilihan terapi paling tepat. Prosedur GKRS yang kompleks meliputi banyak tahap dengan durasi 6-10 jam, memerlukan pemberian anestesi pada pasien yang tidak kooperatif. Kasus ini mengenai pasien anak perempuan berusia 4 tahun dengan cystic craniopharyngioma. Pasien dengan keluhan pandangan mata buram, dari pemeriksaan fisik didapatkan papil atrofi bilateral. Hasil magnetic resonance imaging (MRI) menunjukkan massa tumor yang menekan kelenjar hipofise inferior. Pasien menjalani prosedur GKRS selama 6 jam dengan anestesi sedasi sedang menggunakan Propofol 75 mcg/kg/menit. Hemodinamika selama prosedur stabil, tidak terjadi komplikasi. Pemilihan teknik anestesi dapat berupa anestesi umum atau sedasi, tergantung pada kondisi pasien, dokter anestesi, operator, dan fasilitas. Pertimbangan anestesi pada GKRS antara lain prosedur dilakukan di luar kamar operasi, durasi panjang, transportasi ke beberapa tempat seperti radiologi dan cathlab, imobilisasi kepala untuk mencegah pergeseran frame stereotaktik, pasien sendiri di dalam ruang radiasi, prinsip neuroanestesi pediatrik.Anesthetic Management of Pediatric Patient with Cystic Craniopharyngioma Underwent Gamma Knife RadiosurgeryAbstractCraniopharyngioma is a benign tumor characterized by cystic and calcification, surrounded by vital structures therefor it is difficult to perform total tumor resection. Combination with Gamma knife radiosurgery (GKRS) is the best treatment option. The complexities of GKRS consisting of several phases lasts for 6-10 hours. Anesthesia is needed for uncooperative patients. This is a case of a 4-year-old girl with cystic craniopharyngioma. The patient had chief complaint of blurry vision, physical examinations revealed bilateral papil atrophy. Result of MRI showed tumor mass compressing inferior hypophyse. Patient underwent the procedure under moderate sedation with Propofol at 75 mcg/kg/min for 6 hours. Intraoperative hemodynamic condition was stable without adverse events. Choice of anesthesia either general anesthesia or sedation, depends on the condition of patient, considerations from anesthesiologist dan neurosurgeon, dan availability of facilities. Unique considerations for GKRS are; a non-operating room anesthesia, long duration, transportation to other units such as radiology and cathlab, head of the patients need to be immobilized to prevent frame displacement, the patient will be alone in the treatment room, and principles of pediatric anesthesia and neuroanesthesia.
Peran Ferritin pada Stroke Iskemik Akut Amalia, Lisda
Jurnal Neuroanestesi Indonesia Vol 10, No 2 (2021)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3270.047 KB) | DOI: 10.24244/jni.v10i2.302

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Stroke merupakan defisit neurologis yang terjadi karena jejas fokal akut pada sistem saraf pusat yang semata-mata terjadi karena gangguan vaskuler, termasuk infark serebri maupun perdarahan. Ferritin adalah protein intraselular dan ekstraselular penyimpan zat besi yang penting bagi homeostasis besi dalam tubuh. Ferritin diekspresikan di mikroglia dan makrofag, namun ada juga di dalam neuron. Pada saat terjadi kerusakan sel akibat stroke iskemik, ferritin akan keluar dari sel dan masuk ke dalam serum. Keadaan hipoksia-iskemia pada stroke menginduksi ekspresi dari ferritin pada oligodendrosit dan mikroglia. Saat terjadi stres oksidatif, pembentukan ferritin akan meningkat. Fungsi ferritin pada saat stres oksidatif terjadi, masih kontroversial. Ferritin dalam kondisi tersebut dapat berperan sebagai pembersih (scavenger) dan sebagai donor untuk ion besi bebas. Pasien stroke iskemik dengan lesi yang lebih besar dan defisit neurologis yang lebih berat menunjukkan peningkatan kadar serum ferritin yang lebih tinggi dan kecenderungan terjadinya komplikasi trasformasi perdarahan akan semakin tinggi pula.Role Of Ferritin in Acute Ischemic Stroke: A Literature ReviewAbstractStroke is a neurological deficit that occurs due to acute focal injury to the central nervous system that occurs solely due to vascular disorders, including cerebral infarction or bleeding. Ferritin is an intracellular and extracellular iron storage protein which is essential for iron homeostasis in the body. Ferritin is expressed in microglia and macrophages, and also in neurons. If there is cell damage due to ischemic stroke, ferritin will leave the cells and enter the serum. The hypoxia-ischemic state in stroke induces the expression of ferritin in oligodendrocytes and microglia. When there is oxidative stress, ferritin formation will increase. The function of ferritin in times of oxidative stress is still controversial. Ferritin in this condition can act as a scavenger and as a donor for free iron ions. Ischemic stroke patients with larger lesions and more severe neurological deficits showed higher serum ferritin levels and a higher likelihood of complications of bleeding transformation.
Perbedaan Nilai The Clinic GBS Severity Evaluation Scale (CGSES) dan Skala Disabilitas Sindroma Guillain-Barre (SDSGB) pada Pasien Sindroma Guillian Barre dengan dan tanpa Imunoterapi Sidabutar, Berliana; Ganiem, Ahmad Rizal; Lailiyya, Nushrotul; Kurniani, Nani; Amalia, Lisda; Sobaryati, Sobaryati
Jurnal Neuroanestesi Indonesia Vol 10, No 2 (2021)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2999.551 KB) | DOI: 10.24244/jni.v10i2.328

Abstract

Latar Belakang dan Tujuan: The Clinical GBS Severity Evaluation Scale (CGSES) dikembangkan untuk penentuan imunoterapi pasien Sindroma Guillian Barre (SGB) secara lebih obyektif. Skala Disabilitas SGB (SDSGB) menggambarkan tingkat keparahan SGB dan dapat digunakan menilai efektifitas pemberian imunoterapi. Tujuan penelitian untuk mengetahui perbedaan penilaian CGSES dan SDSGB pasien SGB dengan dan tanpa imunoterapi dan membandingkan kesesuaian keputusan subyektif dengan CGSES. Subjek dan Metode: Penelitian observasional analitik potong lintang komparatif secara retrospektif pada pasien rawat SGB periode Januari 2015 Maret 2020 di RSUP Dr Hasan Sadikin Bandung. Hasil: Terdapat 92 subjek (35 dengan dan 57 tanpa imunoterapi). Rerata usia 41,5 tahun, dengan pria:wanita (57,6%:42,4%). Tidak didapatkan perbedaan demografi dan pemeriksaan fisik kedua kelompok, kecuali paresis saraf kranial (62,9% vs. 33,3%; p=0,006). Terdapat perbedaan rerata lama perawatan dengan dan tanpa imunoterapi (29,534,4 vs. 11,44,1 hari, p=0,0001). Hasil penilaian CGSES pasien SGB dengan dan tanpa imunoterapi memiliki perbedaan bermakna (p=0,035). Terdapat perbedaan signifikan SDSGB saat masuk dan pulang pasien dengan imunoterapi (p=0,007) dan tanpa imunoterapi (p=0,025). Terdapat ketidaksesuaian keputusan subyektif dengan nilai CGSES (nilai Kappa 0,117; CI95% 0,021-0,213)Simpulan: Terdapat perbedaan skor CGSES dan SDSGB pada kelompok pasien SGB dengan dan tanpa imunoterapi. Terdapat ketidaksesuaian penilaian subyektif keputusan pemberian imunoterapi dengan skoring CGSESDifferences in Value of The Clinic GBS Severity Evaluation Scale (CGSES) and Guillain-Barre Syndrome Disability Scale (GBSDS) in Guillian Barre Syndrome (GBS) Patients with and without ImmunotherapyAbstractBackground and objective: The Clinical GBS Severity Evaluation Scale (CGSES) was developed to determine immunotherapy of GBS patients more objectively. GBS Disability Scale (SDSGB) describes severity of GBS and assesses effectiveness of immunotherapy. Purpose of this study was to measure difference of CGSES and GBSDS in GBS patients with and without immunotherapy and to compare the suitability of subjective decisions with CGSES. Subject and Methods: This is a comparative cross-sectional analytic observational study retrospectively in GBS patients from January 2015-March 2020 hospitalized at Dr Hasan Sadikin Hospital, Bandung. Results: There were 92 subjects (35 with and 57 without immunotherapy). Mean age was 41.5 years, and male:female ratio was 57.6%:42.4%. There were no differences in demographics and physical examination between two groups, except for cranial nerve paresis (62.9% vs. 33.3%; p=0.006). There was a difference in mean length of stay with and without immunotherapy (29.5 34.4 vs. 11.4 4.1 days, p=0.0001). Results of the CGSES assessment with and without immunotherapy had a significant difference (p=0.035). There were significant differences in GBSDS at admission and discharge with (p=0.007) and without immunotherapy (p=0.025). There was a discrepancy between subjective decisions and CGSES value (Kappa value 0.117; 95% CI 0.021-0.213).Conclusion: There were differences in CGSES and GBSDS in group of GBS patients with and without immunotherapy. There was a discrepancy between subjective assessment of decision to give immunotherapy with CGSES scoring.
Co-Authors - Elvidiansyah - Elvidiansyah A Himendra Wargahadibrata A Himendra Wargahadibrata A. Muthalib Nawawi A.A. Ketut Agung Cahyawan W Abdul Muthalib Nawawi Abdul Muthalib Nawawi Abdul rachman, Iwan Abdul Rahman Adnin Nugroho Adriana Damayanti Afdi Arahim Putra Agnes Rengga Indrati Agus Susanto Agusti Setiabudi Pramata Ahmad Doni ahmad doni Ahmad Rizal Ahmad Rizal ahmad rizal Ahmad Rizal Ahmad Rizal Ganiem Ahmad Rizal Ganiem, Ahmad Rizal Aih Cahyani Aisyah Ummu Fahma Al Rasyid Amanda Diannisa Azzahra Amany Khansa Amaylia Oehadian Aminuyati Anam Ong Anam Ong Ananda Pratama Kesumaningtyas Gunawan Andi Basuki Prima Birawa Andi Basuki Prima Birawa Andi Basuki Prima Birawa Andre Aditya Andre Tanuwijaya, Andre Andy Hutariyus Anindyta Murfia Khairunnisa Ardhana Risworo Anom Yuswono Ardhana Risworo Anom Yuswono Ardi Zulfariansyah Ardi Zulfariansyah Ardi Zulfariansyah Ardiana Ari Saptadi Ari Saptadi Aries Saifudin Ariestian, Erick Army Zaka Anwary, Army Zaka Arna Fransisca Arsy Felisita Dausawati Arsy Felisita Dausawati Arviana Adamantina Putri Asep Nugraha Hermawan Asep Nugraha Hermawan Asep Nugraha Hermawan Asyer Asyer Ayu, Auliya Putri Badriyah, Nur’aini Jamilatul Berliana, Sobaryati Biben, Vitriana Bisri, Tatang https://scholar.google.co.id/citations?u Bramantyo Pamugar Calista, Chandra Cep Juli Chandra Calista Citra Windani Mambang Sari Dedi Fitri Yadi Defri Aryu Dinata Defri Aryu Dinata, Defri Aryu Dessy Sutoyo Dewi Ramadani Dewi Ramadani Dewi Yulianti Bisri Dian Novitasari Doddy Tavianto Dzulfikar D. L. Hakim Eka Damayanti Eko Nofiyanto Eppy Buchori Eppy Buchori Aristiady Eri Surahman Eri Surahman Erick Ariestian Erwin Pradian Eva Srigita Tari Ezra Oktaliansah Fadila Arsanti Fahma, Aisyah Ummu Fauzan Musyaffa Fifi Veronica Firdaus, Riyadh Fithrah, Bona Akhmad Fithrah, Bona Akhmad Fitri Sepviyanti Sumardi Fitri Yanti Gaga Irawan Nugraha Galuh Saputri Ginna Megawati Glenn Mark Togu Gloria Kartika Gunadharma, Suryani Guntur Darmawan Hamzah Hamzah Hanna Goenawan Hanna Goenawan Hansen Wangsa Herman Haqun Baitika Harahap, M Sofyan Harry Galuh Nugraha Hartiah Haroen Hermawan, Asep Nugraha Hidayat, Dede A Hidayat, Faqih Hidayat, Shaffana Hilman Hilman Hunter D. Nainggolan Hunter D. Nainggolan Ida Parwati Ike Sri Redjeki Ike Sri Redjeki Indra Wijaya Indriasari Indriasari Islami, Aditya Iwan Abdul Rachman Jerico Franciscus Pardosi Jimmy Setiadinata Jimmy Setiadinata, Jimmy Jonathan Jeremi Siagian Kartapraja, Roni D. Kartika, Gloria Khairunnisa, Shafa Ayu Khofifah Nurfaisah Lailiyya, Nushrotul Laniyati Hamijoyo, Laniyati Lee Shok Chen Lee Shok Chen, Lee Shok Leni Lismayanti Liunardo Bintang Pratama Lukman Hidayat Lulu Eva Rakhmilla, Lulu Eva M Andy Prihartono M. Erias Erlangga M. Erias Erlangga, M. Erias Maharani, Nurmala Dewi Mariko Gunadi Mariko Gunadi Marina A. Moeliono Marina A. Moeliono, Marina A. Martaria, Nency Martinus, Fardian Martinus, Fardian Maulana Muhammad Maulana Muhammad, Maulana Mayasari, Ferra Mayasari, Ferra Millata Azma Basmala Muhammad Adjie Pratama Muhammad Mustofa Ramadhan Nadya, Siti Fairuz Nandina Oktavia Nani Kurniani Nesyia Tara Restikasari Neti Juniarti Nur Atiik Nurmin, Rahmawati Nurohman Nushrotul Lailiyya Nushrotul Lailiyya Nushrotul Lailiyya Dahlan Oktivia, Wenny Ong, Paulus Anam Pamugar, Bramantyo Pandji Irani Fianza Paranita Utama Paulus Anam Ong Paulus Anam Ong Paulus Anam Ong Pison, Osmond Muvtilof Pramodana, Bintang Prihatno, M. Mukhlis Rudi Putri, Dini Handayani R, Tubagus Yuli R, Tubagus Yuli Radian Ahmad Halimi Rahmadsyah, Teuku Rahmatisa, Dimas Rahordjo, Sri Ramdan Panigoro Reihan Achmad Reza Reza W. Sudjud Ria Bandiara Richard Pahala Sitorus Rico Defryantho,* Lisda Amalia,* Ahmad Rizal,** Suryani Gunadharma,* Siti Aminah,* Nushrotul Lailiyya* Rini Rustini Rita Arsika Fauziah Riyadh Firdaus Rizkia, Fildza Intan Rizky Gimnastiar Roni D. Kartapraja Rudi Kurniadi Kadarsah Ruli Herman Sitanggang S, Achmad Afif Saleh, Siti Chasnak Saleh, Siti Chasnak Saprudin Saprudin Saputra, Gilang Nispu Sari, Kartika Indah Setiawan Setiawan Shenny Dianathasari Santoso Sidabutar, Berliana Sitanggang, Ruli H. Siti Aminah Siti Aminah Siti Aminah Siti Aminah Siti Aminah Siti Aminah Sobana Siti Nur Fatimah Sitorus, Richard Pahala Siuliyanty, Siuliyanty Sobaryati Sobaryati Sobaryati Sobaryati Sobaryati, Sobaryati Sofiati Dian Sri Rahardjo Sri Rahardjo Sudadi Sudadi Sukmawati, Rani Suryadi Suryadi Suryani Gunadharma Suryani Gunadharma Suryani Gunadharma Sutoyo, Dessy Suwarman, S Suwarman, S Syifa, Nadia Syifa, Nadia Tantarto, Tamara Tatang Bisri Tatang Bisri Theresia C. Sipahutar Theresia C. Sipahutar Theresia Monica Rahardjo Thomas Thomas Tiara Pramaesya Tiene Rostini, Tiene Tinni T. Maskoen Tinni T. Maskoen Tinni T. Maskoen Trislawati, Cristina Trully Deti Rose Sitorus Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani, Uni Vania Angeline Bachtiar Verolia Yunita Putri Wandira, Rega Dwi Wardhani, Ildzamar Haifa Wardoyo, Chandra Calista Wargahadibrata, A. Hmendra Wargahadibrata, A. Hmendra Widiastuti, Monika - Wildan Firdaus Wirayuga Rizkia Suwahyo Yovita Stevina Yunita Susanto Putri Yunita Susanto Putri Yusuf Wibisono Yusuf Wibisono Zamzami, Nyiemas Moya Zamzami, Nyiemas Moya