Article Per Year (5 Year)
p-Index From 2021 - 2026
5.109
P-Index
This Author published in this journals
All Journal Argipa (Arsip gizi dan Pangan) Jurnal Biologi Tropis JURNAL PENDIDIKAN TAMBUSAI Hearty : Jurnal Kesehatan Masyarakat UMI Medical Journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Ners Borneo Journal of Medical Laboratory Technology Indonesian Journal of Global Health research Jurnal Kesehatan Tambusai AKSELERASI: Jurnal Ilmiah Nasional JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Wal'afiat Hospital Journal Journal of Aafiyah Health Research (JAHR) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Innovative: Journal Of Social Science Research WAL'AFIAT HOSPITAL JOURNAL Jurnal Kesehatan Journal Of Medicine And Health Sciences (Medisci) Jurnal Balireso: Jurnal Pengabdian pada Masyarakat
Safitri, Asrini
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 41 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : JOURNAL LA MEDIHEALTICO

 1 
The Effect of Resveratrol on Fasting Blood Glucose Levels as a Parameter of Type 2 Diabetes Mellitus Rahman, Dinda Briliani; Syamsu, Rachmat Faisal; Safitri, Asrini
Journal La Medihealtico Vol. 6 No. 5 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i5.2714

Abstract

characterized by chronic hyperglycemia, insulin resistance, and increased oxidative stress. Resveratrol, a naturally occurring polyphenolic compound, has been widely investigated for its potential antidiabetic effects in preclinical studies, although findings across animal models remain inconsistent and require systematic synthesis. This study aimed to review and synthesize evidence on the effects of resveratrol on glycemic regulation, insulin signaling, lipid metabolism, and oxidative stress in animal models of T2DM. The review followed PRISMA 2020 guidelines. Electronic searches were conducted in PubMed, Scopus, Sinta, and Google Scholar for articles published between 2019 and 2024. Eligible studies were original experimental investigations employing animal models of T2DM with resveratrol as the primary intervention. Owing to heterogeneity in study designs and outcome measures, data were synthesized using a qualitative narrative approach. Seven studies met the inclusion criteria. Overall, resveratrol administration was associated with reductions in fasting blood glucose, improvements in insulin sensitivity, and modulation of key insulin signaling pathways, particularly the PI3K Akt FOXO1 axis. Most studies also reported favorable effects on lipid profiles and reductions in oxidative stress markers. Although one study reported no significant improvement in glycemic indices, the overall pattern indicated consistent positive metabolic effects. This systematic review suggests that resveratrol exerts antidiabetic effects in animal models of T2DM by improving glycemic control, insulin signaling, lipid metabolism, and oxidative stress regulation. However, further well designed studies are needed to clarify dose response relationships and facilitate clinical translation.
Co-Authors Abdi, Dian Amelia Abdullah, Rezky Putri Indarwati Adriana, Delvi Ahmad Ardhani Pratama Ahyar, Farah Firjatillah Aisyah, Windy Nurul Al Qindy, Syech Muh. Ali Aspar Mappahya Alwi, Sitti Rafiqah Amalia D, Nurul Tasya Andi Tenri Sanna Ardiansyah Paputungan, Muhammad Arfah, Arni Isnaini Arifin, Arina Fathiyyah Arifuddin, Andi Tenri Sanna Aryanti R. Bamahry Azikin, Wildana Badruddin, Kartini Bamahry , Aryanti R Bamahry, Aryanti R. Basir, Hasmawati Bima, Irmayanti Haidir Churiani Darariani Iskandar Darussalam, Andi Husni Esa Dedi, Muh.Khaidir Dirgahayu, A. Millaty Halifah Dwi Pratiwi Esa Darussalam, Andi Husni Fattah, Nurfachanti Fendy Dwimartyono Fitriah Fitriah Gayatri B., Sri Wahyuni Gayatri, Sri Wahyuni Guraci, Vaya Gaby Haeriyanty, Haeriyanty Hamzah, Pratiwi Nasir Ida Royani Irmayanti Irmayanti, Irmayanti Irna Diyana Kartika Irsandy, Febie J, Muhammad Akbar Jumaide, Nurul Isnaeni Kamaluddin, Irna Diyana Kartika Karim, Abdul Mubdi Ardiansar Arifuddin Karim, Marzelina Khair, Yaumil Khairunnisa, Siti Fayka Laddo, Nirwana Lantara, A. Millaty Halifah Dirgahayu Loddo, Nirwana M. Yogi Riyantama Isjoni M., Andi Nurdina Maharani, A.Putri Salwa Dita Maharani, Ratih Natasha Mangarengi, Yusriani Mochammad Erwin Rachman, Mochammad Erwin Muchsin, Achmad Harun Mulyadi, Farah Ekawati Muthalib, Iqra Muhamad Zulmadhani Z. N, Hermiaty Namirah, Hanna Aulia Natasha, Ratih Natsir, Pratiwi Nirwan, Siti Fauziyyah Novriansyah, Zulfikri Khalil Nurhikmawati, Nurhikmawati Nurmadilla, Nesyana Nurul Aisyah, Windy Pramono, Sigit Dwi Prema Hapsari Putry, Resti Anisha Rachmat Faisal Syamsu, Rachmat Faisal Rahman, Dinda Briliani Rahmawati, Rahmawati Ratnawati, Wahida Razak, Kaisar Rizki Amalia Rizqi, Ain Tajriani Sani, Resky Mutiara Sjakir, Muh Febri Ananda Sri Julyani Sri Wahyu Suhestin, Cristy Wanti Syahril, Erlin Tahir, Akina Maulidhany Taufik, Muhammad Akram Umar, Uni Numero Risky Usri, Nur Afifah Utami, Dian Fahmi Widyadhana, Narlhiandini Mitresna Wiriansya, Edward Pandu Wisudawan, Wisudawan Wulandari, Nurul Ismi Yudistira, Amanda Tasya Reghinaa Putri Yuniati, Lisa ZA, M. Abrar Naufal Hidayatullah Zulfahmida Zulkifli, Andi Aldita Nitamapia