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All Journal Jurnal SPEKTRUM Jurnal Mahasiswa Fakultas Hukum JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA J-EBIS (Jurnal Ekonomi dan Bisnis Islam) JURNAL PENGABDIAN KEPADA MASYARAKAT Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Jurnal Onoma: Pendidikan, Bahasa, dan Sastra JIKEM: Jurnal Ilmu Komputer, Ekonomi dan Manajemen Jurnal PkM (Pengabdian kepada Masyarakat) JUSTER: Jurnal Sains dan Terapan Media Ekonomi Sejahtera: Jurnal Inspirasi Mengabdi Untuk Negeri Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Jurnal Pendidikan Sosial dan Konseling Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Aspirasi : Publikasi Hasil Pengabdian dan Kegiatan Masyarakat Al-Zayn: Jurnal Ilmu Sosial & Hukum Jurnal Manajemen dan Pendidikan Agama Islam AS-SHIHA: JURNAL KESEHATAN JURNAL AKADEMIK EKONOMI DAN MANAJEMEN Aksi Nyata : Jurnal Pengabdian Sosial dan Kemanusiaan Jurnal Pengabdian Masyarakat Mandira Cendikia (JPKM-MC) Journal Of Pharmacy
Ayu Rahmawati
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Journal : Journal Of Pharmacy

 1 
Evaluasi Penggunaan Obat Anti Hipertensi Pada Pasien Stroke Iskemik Di Rsud Arifin Achmad Tahun 2022 Nawwar Irfan; Nursyafni; Ayu Rahmawati; Mestika, Diani
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Antihypertensive drugs are one of the drugs most commonly given to ischemic stroke patients. Ischemic stroke is a stroke resulting from thrombosis or embolism that occurs in the cerebral blood vessels and causes obstruction of cerebral blood flow to the cerebral blood vessels. The use of drugs is rational if the patient receives treatment according to his clinical needs. The aim of this study was to determine the appropriate use of antihypertensive drugs in ischemic stroke patients based on the right indication, selection of the right drug, right dose and determine the relationship between sociodemographics and the results of antihypertensive treatment in ischemic stroke patients at Arifin Achmad Regional Hospital. The method used in this research is a descriptive observational method using retrospective data which was carried out by recording medical record data of patients with a final diagnosis of ischemic stroke accompanied by hypertension with a sample size of 80 patients. people (52.5%), 45-64 years old 44 people (55%), working patients 53 people (66.3%), and the most widely used drug class was amlodipine as many as 67 people (56.8%). In the results of the chi-square test with a significance value of p value = 0.05 for the relationship between age and gender on risk factors, the age value was p = 0.004, while the gender value was p = 0.014. It was concluded that the evaluation of the use of antihypertensive drugs at Arifin Achmad Hospital was 100% correct and showed that age and risk factors were related, and gender and risk factors were related. Keywords: Hypertension, ischemic stroke, evaluation of drug use
Evaluasi Penggunaan Obat Antihipertensi Primer Pasien Lanjut Usia Periode Januari – Juni 2022 Di Puskesmas Minas Ayu Rahmawati; Dewi Gulyla Hari; nisa, Annisa Nurul Maharani
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Hipertensi adalah keadaan seseorang yang mengalami peningkatan tekanan darah di atas normal, yaitu tekanan darah sistolik ≥ 140 mmHg dan atau tekanan darah diastolik ≥ 90 mmHg. Tujuan penelitian ini adalah untuk mengetahui ketepatan penggunaan obat antihipertensi primer dan hubungan Sosiodemografi terhadap hasil pengobatan pasien di Puskesmas Minas periode januari – juni tahun 2022. Metode yang digunakan adalah metode deskriptif dengan rancangan non ekperimental. Data penelitian diperoleh dari berkas catatan medik yang dikumpulkan dengan teknik pengumpulan secara purposive sampling dengan jumlah sampel sebanyak 110 pasien yang berusia lanjut. Pada hasil penelitian ini menunjukkan data karakteristik pasien yang paling banyak yaitu jenis kelamin perempuan sebesar 69 orang (62,7%), kelompok usia 45-59 tahun 53 orang (48,2%), pasien yang tidak bekerja 81 orang (73,6), dan golongan obat yang banyak digunakan yaitu amblodipin sebesar 107 pasien (97,2%). Pada hasil uji chi-square dengan nilai kemaknaan p value = 0,05 terhadap hubungan umur dan jenis kelamin terhadap faktor resiko didapatkan nilai umur adalah p = 0,873 sedangkan jenis kelamin memiliki nilai p = 0,000. Disimpulkan bahwa evaluasi penggunaan obat antihipertensi di Puskesmas Minas sudah 100% tepat dan menunjukkan bahwa umur dengan faktor resiko tidak memeliki hubungan, sedangkan jenis kelamin dengan faktor resiko memeliki hubungan. Untuk penelitian lebih lanjut diharapkan dapat melakukan observasi terhadap 2 tempat atau lebih sebagai pembanding untuk hasil yang lebih bervariatif.
Evaluasi Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Primer Rawat Jalan Lanjut Usia Periode Januari 2022 – Juli 2023 Di RSUD Arifin Achmad Provinsi Riau Nawwar Irfan; Ayu Rahmawati; Nurbaiti; Aulia Fitri, Windy
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Abstract

Hypertension is a condition where the increase in systolic blood is above the normal limit, which is more than 140 mmHg and diastolic blood pressure is more than 90 mmHg. The purpose of this study was to determine the sociodemographic relationship to the treatment outcomes of hypertensive patients and to examine patterns of antihypertensive drug use at Arifin Achmad Hospital, Riau Province. The method used in this study was an observational descriptive method using retrospective data which was carried out by recording medical record data and the research subjects used in this study were outpatients with a diagnosis of hypertension with a total sample of 90 elderly patients. The results of this study showed that the most data on patient characteristics, namely female sex, amounted to 66 people (73.3%) and the most widely used drug class, namely amlodipine, was 76 patients (62.3%). On the results of the chi-square test with a significance value of p value = 0.05 for the relationship between age and gender for risk factors, the age value was p = 0.123 while gender had a p value = 0.000. It was concluded that the evaluation of antihypertensive drugs was 100% correct and showed that age and risk factors had no relationship, while gender had a relationship with risk factors.
Potensi Aktivitas Ekstrak Etanol Daun Pucuk Merah (Syzygium myrtifolium Walp.) sebagai Antihiperurisemia pada Mencit Putih (Mus musculus) Lusi Indriani; Ayu Rahmawati; Nursyafni; Nawwar Irfan; Novita Sari
The Journal Of Pharmacy Vol. 1 No. 1 (2023): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Hyperuricemia is a condition where uric acid production increases or the kidneys cannot remove uric acid from the body so that uric acid levels in the blood exceed 7.0 mg/dL in men and 6.0 mg/dL in women. One of the secondary metabolites that have the potential to act as anti-hyperuricemia is flavonoids. Red shoots contain flavonoids, alkaloids, terpenoids, chalcones, and tannins. This study aimed to determine the anti-hyperuricemia activity of ethanol extract of red shoots (Syzygium myrtifolium Walp.) in white mice. This study used 16 male white mice which were randomly divided into 4 treatment groups. Group 1 was negative control (Na-CMC 0.5%), group 2 was positive control (allopurinol 300 mg/KgBW), group 3 was dose 1 (pucuk merah ethanol extract 10 mg/kgBW), and group 4 was dose 2 (pucuk merah ethanol extract 15 mg/KgBW). Before giving treatment, mice were first induced with KBrO3 at a dose of 148 mg/KgBW intraperitoneally and initial uric acid levels were measured. Then each group was given oral treatment. Uric acid levels were measured at 30, 60, and 90 minutes. The results showed that the pucuk merah ethanol extract 15 mg/KgBW (dose 2) had an anti-hyperuricemia activity of 62.42% compared to allopurinol 65.80%.
Tingkat Pengetahuan Dan Perilaku Swamedikasi Penggunaan Obat Bebas Pada Masyarakat Di Kecamatan Simpang Kanan Kabupaten Rokan Hilir Ayu Rahmawati; Nursyafni; Novtafia Endri; Muhammad Arif; Nawwar Irfan; Wulandari, Tri Ayu; Fitratul Wahyuni
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Self-medication is an act of self-medication carried out by the community to maintain health or manage disease based on personal diagnosis, using drugs repeatedly. This study aims to analyze the relationship between knowledge level and self-medication behavior using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency. The research was conducted observational with a cross-sectional approach, using quota sampling technique and questionnaires as instruments. The results showed that out of 90 respondents, 77.8% had good knowledge, 21.1% had sufficient knowledge, and 1.1% had poor knowledge. In terms of behavior, 81.1% had good behavior, while 18.9% had moderate behavior in self-medication. Analysis using the Chi-Square test resulted in a p-value of 0.002 (p<0.05), indicating a significant relationship between the level of knowledge and behavior of self-medication using over-the-counter drugs in the community in Simpang Kanan District, Rokan Hilir Regency.
Uji Aktivitas Antioksidan Ekstrak Etanol 70% Daun Pandan Wangi (Pandanus amaryllifolius Roxb) Dengan Metode DPPH Muhammad Arif; Ayu Rahmawati; Noveri Rahmawati; Nursyafni; Indah, Indah Kurniawati
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Antioxidants and free radicals are topics that are increasingly discussed in the field of health and lifestyle. Free radicals, which result from oxidative stress, are known to play a role in the development of many serious diseases, such as cancer, cardiovascular disorders and premature aging. Antioxidants are able to neutralize free radicals, thus having the potential to prevent or reduce the impact of these diseases. This study aims to evaluate the antioxidant activity of ethanol extract of pandan wangi leaves (Pandanus amaryllifolius Roxb) using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method and determine the IC50 value as an indicator of effectiveness. Experimental methods were used to analyze antioxidant activity, with DPPH assays performed using a UV-Vis spectrophotometer. The results showed that the ethanol extract of pandan leaves had an IC50 value of 180.21 µg/mL, which was slightly lower than vitamin C as a positive control with an IC50 value of 136.03 µg/mL. Nevertheless, the antioxidant activity of pandan leaf extract is still in the moderate category, indicating its potential as a source of natural antioxidants. This study also emphasizes the importance of technical factors, such as temperature, incubation duration, and solvent quality, in influencing the test results. This study opens up opportunities for further development in the optimization of extraction and utilization of pandan wangi leaves as a natural ingredient to fight oxidative stress.
Hubungan Tingkat Pengetahuan, Sikap Siswa SMAN Se- Kota Pekanbaru Terhadap Praktik Penggunaan Obat Analgetik Yang Dijual Bebas Di Pasaran Ayu Rahmawati; Nursyafni; Nurhasanah; Efilia Meirita
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Analgesics are drugs that are often used to relieve pain without affecting a person's consciousness. This study aims to determine the relationship between the level of knowledge, attitudes of SMAN students in Pekanbaru City towards the practice of using analgesic drugs sold over the counter on the market. This study uses a descriptive survey method with a sampling technique, namely the simple random sampling technique using a questionnaire instrument. Where there were 367 respondents involved in this study, dominated by 204 females and 163 male respondents. The age range is 15-18 years, the majority of whom are 16 years old. Data analysis using bivariate using chi square test and multivariate using F test. The results showed that the level ofknowledge was sufficient 251 respondents (68.4%), positive attitude 311 (84.7%) and lack of practice as many as 276 (75.2%). In bivariate analysis there was a significant relationship between knowledge of the practice of using analgesic drugs with (p value = 0.000 <0.05). There was no significant relationship between attitudes towards the practice of using analgesic drugs with (p value = 0.0716 > 0.05). This study emphasizes the importance of education about the use of analgesic drugs among high school students to prevent drug abuse
Evaluasi Tingkat Pengetahuan dan Perilaku Terhadap Penggunaan dan Resistensi Antibiotik Di Kalangan Mahasiswa Farmasi Universitas Muhammadiyah Riau Nursyafni; Ayu Rahmawati; Shakynna Suandha
The Journal Of Pharmacy Vol. 2 No. 1 (2024): Journal Of Pharmacy UMRI
Publisher : LPPM, Universitas Muhammadiyah Riau

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Antibiotik adalah obat yang digunakan untuk mencegah dan mengobati infeksi bakteri, yang merupakan salah satu jenis obat yang paling umum dan banyak digunakan di masyarakat. Penelitian ini bertujuan untuk mengidentifikasi distribusi karakteristik responden dan hubungan antara ingkat pengetahuan serta perilaku terhadap penggunaan antibiotik di kalangan mahasiswa farmasi Universitas Muhammadiyah Riau. Sampel penelitian terdiri dari 86 orang yang didominasi oleh perempuan (87,2%), sementara laki-laki hanya berjumlah 12,8%. Rentang usia responden berkisar antara 18 hingga 22 tahun, dengan mayoritas berada pada usia 19 dan 21 tahun, yang bersama-sama mencakup 59,3% dari total sampel. Hasil penelitian menunjukkan bahwa sebagian besar responden memiliki tingkat pengetahuan yang baik mengenai penggunaan antibiotik, dengan 94,2% responden berada dalam kategori ini. Selain itu, perilaku penggunaan antibiotik di kalangan responden juga tergolong baik, dengan 100% responden menunjukkan perilaku yang positif. Analisis statistik lebih lanjut mengungkapkan adanya hubungan yang signifikan antara tingkat pengetahuan dan perilaku penggunaan antibiotik, dengan nilai p sebesar 0,000 (p<0,05). Hasil ini menunjukkan bahwa tingkat pengetahuan yang lebih tinggi berkorelasi positif dengan perilaku yang lebih baik dalam penggunaan antibiotik. Temuan ini menggarisbawahi pentingnya pendidikan yang memadai dalam meningkatkan pengetahuan tentang penggunaan antibiotik yang tepat, yang pada gilirannya dapat mempengaruhi perilaku penggunaan yang lebih bertanggung jawab di kalangan mahasiswa.
Co-Authors Abdul Azis Ade Rizki Nurmayadi Afifah Avilani Afrah Hasna Fadhilah Agus Supriatman Aisyah Yaumul Furqan Alpin Maulana Amiruddin Yahya Apriyana Triwulan Arvyndho Derra Aulia Fitri, Windy Binti Nuriyatul Muthi’ah Cepi Rahmat Hidayat Chandra Rizky Noviandi Dede Syahrul Anwar Devi Sri Agustin Dewi Nurhaliza Diana Santi Edi Suhardiana Efilia Meirita Elysa Eka Endang Lestari Ermira Nilansari Putri Esa Mahesa Evi Dewi Sri Mulyani Fauziah Tazkia Nur Fitratul Wahyuni Fitri Pujiyanti Fitria, Sarah Galih Pambayun Gya Tri Lestari Hafizhah Nur Istiqomah Hanif Nur Fauzan Hari, Dewi Gulyla Hyasintha Aryanti I Made Suartika Ida Bagus Gede Manuaba Indah, Indah Kurniawati Jannah, Nurul Kamiel Roesman Bachtiar Lusi Indriani Maulida Nur Maya Rida Us Alifah Mestika, Diani Miftakhul Huda Muhammad Arif Muhammad Nur Zakia Mutiara Harkit Kamilatul Pu’adah N. Nurjanah Nabila Destiana Naufal Anasyi Nawwar Irfan Nevi Susianty Nggulam Zakia Nilama Wadnaty nisa, Annisa Nurul Maharani Nitya Nurul Fadilah Nofriyaldi, Ali Nola Fitri Noveri Rahmawati Novita Sari Novtafia Endri Nurbaiti Nurhasanah Nurjannah Nursyafni Nurul Fahida Oktavianus Sarno Prasiska Kholidya Prembayun Miji Lestari Rahmat Permana Reja Firman Saputra Rizky Nurul Melyani Rizky Subagya Rizva Alvina Rudi Hartono Shakynna Suandha Shinta Siti Sundari Siti Nabilah Hasna Sri Purnama Sari Srie Rezeki Nur Endah Sukarni Sunanih Teguh Ikhlas Ramadhan Teuku Mufizar Tsalitsatul Maulidah Ulfa Lailatul Vincent O. Imieje Wida Purwidianti Widhi Wicaksono Widya Nurul Aini Wilda Prasetya Winarti Wulandari, Tri Ayu YANTO Yulika Wati Zahra Aulia Nugraha