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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Indonesian Journal of Tropical and Infectious Disease Jurnal Media Gizi Indonesia (MGI) The Indonesian Biomedical Journal PAEDAGOGIA Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) AcTion: Aceh Nutrition Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Indonesian Journal of Medicine Journal of Maternal and Child Health Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Journal of Community Empowerment for Health Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Abdidas Indonesian Journal of Global Health research JURNAL ETIKA KEDOKTERAN INDONESIA Nusantara Science and Technology Proceedings Jurnal Pengabdian Masyarakat Sasambo Proceedings of the International Conference on Nursing and Health Sciences Proceeding Muhammadiyah International Public Health and Medicine Conference The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Smart Society Empowerment Journal Media Dermato-Venereologica Indonesiana Media Penelitian dan Pengembangan Kesehatan Jurnal Epidemiologi Kesehatan Indonesia
Tri Nugraha Susilawati
Department Of Microbiology, Faculty Of Medicine, Sebelas Maret University, Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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EFFECT OF RED BEANS AND BLACK BEANS WITH A DIABETES MELLITUS: A SYSTEMATIC REVIEW Pratiwi; Adi Magna Patriadi Nuhriawangsa; Tri Nugraha Susilawati
Muhammadiyah International Public Health and Medicine Proceeding Vol. 3 No. 1 (2023): PROCEEDING MUHAMMADIYAH INTERNATIONAL PUBLIC HEALTH AND MEDICINE CONFERENCE - T
Publisher : Fakultas Kesehatan Masyarakat Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61811/miphmp.v3i1.411

Abstract

Diabetes mellitus is a chronic metabolic disease that requires dietary management. One of the diet strategies is a high consumption of antioxidants and fiber contained in red beans and black beans. The purpose of this article is to prove that red beans and black beans can treat diabetes mellitus. The method is a systematic review using the PRISMA protocol and JBI's Critical Appraisal Tools. The source of the article is experimental studies published in the last 10 years (2013-2023) in Google Scholar, Pubmed, and Science Direct databases. The results showed that red beans and black beans are rich in antioxidants and fiber. Antioxidants and fiber are known to reduce blood glucose levels and increase insulin levels. The conclusion of this article is red beans and black beans can treat diabetes mellitus. The suggestion of this review is that better to increase the daily dose of red beans and black beans consumption to treat diabetes.
The Relationship Between Education, Occupation, and Nutritional Status with Fasting Blood Glucose Levels in Type II Diabetes Mellitus Patients at Jasa Kartini Hospital Tasikmalaya City in 2023 Nurgajayanti, Cendi; Susilawati, Tri Nugraha; Wiboworini, Budiyanti
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4309

Abstract

The World Health Organization states that diabetes mellitus is caused by several contributing factors including age, gender, education, lifestyle, physical activity, obesity, and family history. This study aims to investigate the relationship between education, occupation, and nutritional status, with fasting blood glucose levels in type 2 diabetes mellitus patients at the outpatient department of Jasa Kartini Hospital in Tasikmalaya City in 2023. An analytical observational study with a cross-sectional design was conducted using secondary data from medical records of 210 samples of diabetes mellitus patients from January to December 2023. Simultaneous assessments were made for each variable, namely education, occupation, nutritional status, and fasting blood glucose levels. The analysis results indicate that the relationship between education and fasting blood glucose levels yielded a p-value of 0.032, while the relationship between occupation and fasting blood glucose levels yielded a p-value of 0.029. However, the relationship between nutritional status and fasting blood glucose levels resulted in a p-value of 0.450. There is a relationship between education and fasting blood glucose levels, there is a relationship between occupation and fasting blood glucose levels, and there is no relationship between nutritional status and fasting blood glucose levels.
The effects of raja banana (Musa acuminata) peel extract on body weight, body mass index, body fat percentage, and visceral fat mass in male rats with obesity Devina, Kezia Elian; Indarto, Dono; Susilawati, Tri Nugraha; Wiboworini, Budiyanti
Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) VOLUME 12 ISSUE 2, 2024
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/ijnd.2024.12(2).115-125

Abstract

Background: Obesity is a risk factor for metabolic syndrome which can increase mortality. Obese sufferers often fail to lose body weight (BW) through non-pharmacological therapy. Obesity synthetic drugs can cause side effects, so natural ingredients are needed as alternative therapies.Objectives: This study aims to determine the effect of raja banana peel extract (RBPE) on BW, body mass index (BMI), body fat percentage (BFP), and visceral fat mass in obese male rats.Methods: The research subjects were 30 male Wistar rats weighing 125-200 g, aged eight weeks. Obesity was induced by being given high-fat high fructose (HFHFr) feed for 28 days. Rats were randomized and divided into five groups: the negative control group (C-) was given standard feed and distilled water, the positive control (C+) was given standard feed and orlistat, treatment 1 (T1), treatment 2 (T2), and treatment 3 (T3). Which were given standard feed and RBPE doses of 200 mg/kgBW/day, 400 mg/kgBW/day, and 800 mg/kgBW/day. Data before and after the induction of obesity were analyzed using paired t-tests. BW, BMI, and visceral fat mass were analyzed using the One-Way Analysis of Variance (ANOVA) and Repeated Measure ANOVA tests. BFP was analyzed using the Kruskal-Wallis test and the Friedman test.Results: RBPE can significantly reduce BW (p=0.026), BMI (p<0.001), and BFP (p<0.001). However, all groups had no significant difference in visceral fat mass (p=0.187). T3 was the group with the lowest average BW, BMI, BFP, and visceral fat mass although the highest weight loss during the intervention period occurred in C+.Conclusions: RBPE has the potential as an alternative therapy for obesity because it can reduce BW, BMI, and BFP. Future studies can investigate the effect of RBPE on other obesity parameters such as lipid profiles.
Elevated Growol Flour Reduce Fasting Blood Glucose, HOMA-IR and Increase Insulin Level in Rat Model with Type 2 Diabetes Mellitus Nofia, Yasinta; Wasita, Brian; Susilawati, Tri Nugraha
Media Gizi Indonesia Vol. 17 No. 2 (2022): JURNAL MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v17i2.151-158

Abstract

The rise of glucose levels in the blood of patients with type-2 diabetes mellitus (T2DM) is attributed to the decrease of insulin secretion and the interruption of insulin activity. Growol is a fermented product made from cassava that has the potential to lower blood glucose levels in patients with T2DM. This study was aimed to evaluate the effects of oral administration of growol flour on the levels of blood glucose, insulin, and HOMA-IR. A total of 40 male Wistar rats were divided into 5 groups i.e., negative control group, positive control group taking metformin, and 3 treatment groups taking growol flour of 3.1, 6.2, and 9.3 (g/200gBW), respectively, for 2 weeks. Blood glucose levels were measured using Enzymatic Photometric Method GOD-PAP, insulin using the ELISA kit, and HOMA-IR using the formula. The Shapiro Wilk test was used to determine the normality of the data followed by the One-Way ANOVA test and Posthoc Tukey HSD test. The Paired T-test was used to see the difference of pre- and post-treatment levels of blood glucose, insulin, and HOMA-IR. There was a decrease (p<0.05) in blood glucose levels and HOMA-IR after the administration of low, moderate, and high doses of growol flour. In contrast, the levels of insulin increased (p<0.05) after the administration of low, moderate, and high doses. In conclusion, growol flour contributes to the maintenance of T2DM by lowering the levels of fasting blood glucose levels, as well as HOMA-IR, and increasing the levels of insulin in rats.
KOMBINASI KACANG MERAH DAN KULIT KACANG HITAM PADA TIKUS WISTAR MODEL DIABETES MELITUS TIPE 2 Wulandari, Pratiwi; Nuhriawangsa, Adi Magna Patriadi; Susilawati, Tri Nugraha
Media Penelitian dan Pengembangan Kesehatan Vol. 34 No. 1 (2024): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v34i1.1846

Abstract

Type 2 Diabetes Mellitus (T2DM) is a metabolic disease that require pharmacological and non-pharmacological therapies. Comsuming functional foods that are high in antioxidants and fiber such as red beans and black beans beneficial to patients with T2DM. The study aimed to examine the effect of the combination of red beans (Phaseolus vulgaris L.) flour and black beans (Phaseolus vulgaris) coat extract on body weight, blood glucose, insulin level and pancreatic tissue of T2DM model rats. This randomized controlled trial involved 36 male Wistar rats divided into 6 groups consisted of non-diabetic rats (Group I) and nicotinamide-streptozotocin induced diabetic rats (Group II-VI). Group II was negative control; Group III-V were given a combination with the proportion of flavonoid/ fiber in each kgBW as follows: 22.5 mg/0.25 g; 45 mg/0.5 g; and 90 mg/1 g. Group VI was the positive control. Data on body weight, fasting blood glucose levels and insulin levels were analyzed using Two-Way Anova, while pancreatic histopathology scoring data used Kruskal-Wallis.There was a significant difference between the dose and duration of intervention on body weight, fasting blood glucose and insulin levels (p=0.001). The intervention groups showed there were no pancreatic histopathology change as good as the positive control (p>0.05). The combination of flavonoids and fiber at a dose of 45 mg/0.5 g per kgBW was proven to gain weight, reduce fasting blood glucose levels, increase insulin levels and no pancreatic histopathology change in T2DM rats models as well as the postive control group.
ANALISIS FAKTOR-FAKTOR YANG MENGHAMBAT KAJI ETIK PROTOKOL PENELITIAN: STUDI PADA KOMITE ETIK PENELITIAN FAKULTAS KEDOKTERAN UNIVERSITAS SEBELAS MARET, SURAKARTA Susilawati, Tri Nugraha; Putri, Noviyati Rahardjo; Ardhi, Tunggul
Media Penelitian dan Pengembangan Kesehatan Vol. 34 No. 3 (2024): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v34i3.2084

Abstract

Ethics review is essential prior to conducting research involving humans and animals. This study aimed to evaluate the effectiveness of ethics review procedures and identify the causes of delayed ethical approval of the protocols submitted to Research Ethics Committee of the Faculty of Medicine, Universitas Sebelas Maret during 2022-2023. Retrospective data collected include protocol identity number, institution and educational level of the proposer, research type, date of protocol submission, completion of initial ethics review, and issuance of the ethical clearance certificate. A total of 458 protocols were received over 2 years period but the processing of 8 protocols were discontinued so that those 8 protocols were excluded from further analysis. Of the 450 protocols analysed, most involved human subjects (331; 73.6%). The majority of proposers were from UNS (309; 68.7%), were students (353; 78.4%), and had undergraduate education (166; 36.9%). The duration of the initial ethics review was generally <2 weeks (90.4%). Most (92.7%) protocols needed revision. The majority (66.4%) of proposers needed <2 weeks to revise the protocol. The total time for the entire ethics review process was 22.9 ± 14 days. Further evaluation found that the average duration needed for protocol revision was longer than that for reviewing (16 vs 9 days). It can be concluded that the ethics review process ran effectively so that almost all protocols submitted could undergo initial reviews in a relatively short time. The delayed ethical approval was due to the slow protocol revision process by the proposers.
DURASI MENDERITA DM MEMENGARUHI KONTROL GLIKEMIK JANGKA PANJANG YANG DIUKUR MELALUI HbA1c PADA PASIEN DIABETES MELITUS TIPE 2 Nurgajayanti, Cendi; Susilawati, Tri Nugraha; Wiboworini, Budiyanti
Media Penelitian dan Pengembangan Kesehatan Vol. 34 No. 3 (2024): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v34i3.2085

Abstract

Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia due to abnormalities in insulin secretion or action. In West Java, the prevalence of DM reached 1.9%, with a significant increase in Tasikmalaya City, which recorded 7,436 cases in 2022. This study aimed to explore the relationship between individual characteristics, nutritional status, comorbidities, and duration of DM with HbA1c levels in type 2 diabetes patients at one of the private hospitals in Tasikmalaya City.This study evaluated medical records of 210 patients with type 2 DM. The Spearman's rank correlation test was used to analyse the relationships between variables and a p<0.05 was considered as statistically significant. The research design used is cross sectional with purposive sampling technique.The result showed there was a statistically significant relationship between the duration of illness and HbA1c levels (p = 0.001 and r = 0,072). However, the relationship  between nutritional status or comorbidities and HbA1c levels were not statistically significant (p = 0.471 and 0.187, respectively), indicating no relationship between nutritional status and HbA1c levels. The study concluded there was no significant relationship between nutritional status and comorbidities with HbA1c levels. Namun, ada hubungan antara durasi penyakit dengan kadar HbA1c
VITILIGO SEGMENTAL PADA ANAK YANG DITERAPI DENGAN REGIMEN MOMETASONE FUROATE 0,1%, SOLANUM LYCOPERSICUM L 3%, DAN CERAMIDE (MSC) Suhartono, Suhartono; Ridha Setiawati; Rahmat Sugianto; Radityastuti; Armita Asri Apsari; Tri Nugraha Susilawati
Media Dermato-Venereologica Indonesiana Vol 52 No 1 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i1.517

Abstract

Pendahuluan: Vitiligo adalah penyakit depigmentasi (hipomelanosis) didapat pada kulit, membran mukosa, dan rambut yang berbatas tegas, disebabkan oleh hilangnya melanosit secara progresif. Vitiligo biasanya muncul pertama kali saat masa anak-anak atau dewasa muda. Kasus: Seorang anak perempuan berusia 21 bulan 3 minggu timbul bercak putih di pantat sejak usia 5 bulan. Pemeriksaan fisik ditemukan makula depigmentasi, simetris, berbatas tegas, bentuk menyerupai popok ukuran ± 15 cm x 16 cm. Pemeriksaan dengan lampu Wood didapatkan makula berwarna putih seperti kapur dan berbatas tegas. Terapi yang diberikan adalah regimen MSC selama 5 bulan yang terdiri dari mometasone furoate 0,1%, Solanum lycopersicum L 3 % dan ceramide. Diskusi: Faktor- faktor yang berperan dalam proses terjadinya vitiligo antara lain genetik, autoimun, stress oksidatif dan pajanan bahan kimia. Sel T CD8+ berperan penting dalam proses terjadinya vitiligo dengan cara menyerang melanosit dan menghancurkannya. Peningkatan Reactive Oxygen Species (ROS) dapat menyebabkan kerusakan pada melanosit. Pasien ini diberikan steroid topikal mometason furoate 0,1% sebagai terapi lini pertama, dikombinasikan dengan antioksidan dari Solanum lycopersicum L 3% untuk mengurangi kerusakan melanosit akibat ROS, dan ceramide diberikan untuk memperbaiki sawar kulit sehingga progres perjalanan penyakit tidak menjadi lebih buruk. Kesimpulan: Regimen MSC efektif untuk mengobati vitiligo luas pada kasus ini dan dapat ditoleransi dengan baik tanpa menimbulkan efek samping. 
Aplikasi Antimicrobial Susceptibility Test (AST) dalam Mendeteksi Carbapenem-Resistant Enterobacteriaceae (CRE): Sebuah Tinjauan Sistematis Yasmin, Thania; Mashuri, Yusuf Ari; Maryani, Maryani; Susilawati, Tri Nugraha
Majalah Kedokteran Indonesia Vol 73 No 3 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.3-2023-991

Abstract

Introduction: Indonesia has the highest prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in Asia. This shows the importance of early detection and treatment of CRE cases. This systematic review presents recent studies on the global pravelence of CRE, the use of antimicrobial susceptibility test (AST) for detecting CRE, and detection methods of carbapenemase-producing CRE (CP-CRE). Method: A systematic review was conducted on English scientific articles published in PubMed, Science Direct, and Scopus from January 2018 to February 2022. Inclusion criteria were studies that performed CRE examination on human samples and the keywords were ‘antimicrobial susceptibility test’ OR ‘microbial sensitivity test’ OR ‘antimicrobial susceptibility breakpoint determination’ AND ‘carbapenem-resistant Enterobactericeae’ OR ‘carbapenemase-producing Enterobacteriaceae’. The study selection was carried out according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Result: The literature search and study selection method resulted in a total of 11 articles for data extraction and analysis. The prevalence of CRE was 9.6% in the study that aimed for CRE screening. CRE is detected mostly by Vitek-2® in urine and blood samples showing imipenem and meropenem-resistant bacteria. Conclusion: The prevalence of CRE was high in the CRE case screening study. The most common CRE detection method is Vitek-2® that could be replaced with disk diffusion method in limited resources settings. CRE detection can be followed by the detection of carbapenemase-producing CRE (CP-CRE) by using genotypic, phenotypic, and fluorogenic assays.
Identification of nutrients and phytochemicals of raja banana (Musa acuminata) peels extracted with ethanol and acetone solvents and its potential as an anti-obesity agent Susilawati, Eva; Indarto, Dono; Susilawati, Tri Nugraha
AcTion: Aceh Nutrition Journal Vol 10, No 2 (2025): June
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i2.2483

Abstract

Banana peel is a waste that has the potential as an anti-obesity agent due to its nutritional and phytochemical content. This study aims to analyze and compare the content of macronutrients, micronutrients, and phytochemical compounds in raja banana peel extracts. The maceration method was performed during the preparation of extracts by using ethanol and acetone solvents. The nutritional and phytochemical contents of the extracts were compared to determine which solvent produced the optimum anti-obesity properties. The ethanol extract consists of water (17,68%), minerals (22,76%), protein (3,50%), carbohydrates (47,98%), and vitamin C (0,82%). The phytochemical content includes flavonoids (73,38 mgQE/g), tannins (0,32%), and chrysin (1,16 mg/L). In conclusion, the ethanol extract of Raja banana peel contains higher nutrients and phytochemicals than the acetone extract, showing greater potential as an anti-obesity agent. Further research is needed to test its bioactivity in vivo or in vitro.
Co-Authors 'Ulwiyah, Nuuriyah Adi Magna Patriadi Nuhriawangsa Adiby, Zulfi Azam Adisetya Wicaksono Ainor Rohmah Ardhi, Tunggul Armita Asri Apsari Atik Susianto Basaria, Kevyn Benedictus Aditya Satya Laksana Adji Bernarda, Clarisca Calcafiorentina Bhisma Murti Billah, Muhammad Muayyad Brian wasita Brian Wasita Brian Wasita Buamona, Nur Sitra Budiyanti Wiboworini Cahyaningrum, Nabilla Fitria Cahyanto, Erindra Budi Darmayanti, Aquartuti Tri Defitaria Permatasari Dewi Pratiwi Diana Nurrohima Dono Indarto Dono Indarto Dono Indarto Eriana Melinawati Erindra Budi Cahyanto Erindra Budi Cahyanto Fahmi, Muhammad Izzul Widad Grhasta Dian Perestroika Hasibuan, Wahyu Aulia Heru Priyanto HERU SULASTOMO Heru Sulastomo Hilmy, Farhan Indallah, Nabila Wajihan Ismanta, Anestasia Darmastuti Jusup, Sinu Andhi Kezia Elian Devina Kusmadewi Eka Damayanti Kusmadewi Eka Damayanti Kusumastuti, Wijayanti Larasati, Riska Leli Saptawati Leli Saptawati Lutfinayati, Sofia Marisa Rizqiana Maryani Maryani Mashuri, Yusuf Ari Mufidah, Amatullah Nandyantami, Farah Fauziah Nazili, Muhammad Haqin Niniek Purwaningtyas Niniek Purwaningtyas Nofia, Yasinta Nugraha, Yanika Tiara Nurgajayanti, Cendi Prastyoningsih, Aris Pratiwi Pratiwi Wulandari Puspitasari, Reni Nur Putra, Wahyu Pratama Putri, Noviyati Rahardjo Radityastuti Rahmat Sugianto Ratna Dwi Restuti Ratna Kusumawati Ratna Kusumawati Ratnasari, Affi Angelia Rauf, Muhammad Abdul Ridha Setiawati Riska Larasati Saputri, Nurul Aini Suria Satria, Yohanes Aditya Adhi Satria, Yohanes Aditya Adhi Septiana, Yesika Cahya Setyo Sri Rahardjo Setyo Sri Rahardjo Sigit Setyawan Sri Wulandari Sri Wulandari Suhartono Susianto, Atik Susilawati, Eva Sutarno Sutarno Syaputri, Dwi Triyanta Yuli Pramana Triyanta Yuli Pramana Uki Retno Budihastuti Usman Sudarmaji Usman Sudarmaji Vitri Widyaningsih Widiasih, Ghina Widyaningrum, Sherly Asri Wijiwinarsih, Amallia Winda Rahayuningtyas Winda Rizki Pebrina Batubara Yasmin, Thania Yuliana Heri Suselo Zahida, Sarah