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Journal : Journal of Issues in Midwifery

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The Effect of Giving Soursop Fruit Juice (Annona muricata, L.) on Hemoglobin Levels in Wistar Bunting Strain Rats Exposed to Cigarette Smoke Prastanti, Ryan Hani; Nurdiana; Dewi, Mustika
Journal of Issues in Midwifery Vol. 8 No. 2 (2024)
Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.JOIM.2024.008.02.4

Abstract

Background: Anemia in pregnancy can be caused by exposure to cigarette. A large number of free radicals can cause the number of erythrocytes to decrease. It takes a component to neutralize free radicals, namely antioxidants obtained from various fruits. Soursop contains sources of antioxidants such as flavonoid compounds, polyphenols, and vitamin C. Researchers want to know whether soursop juice can be used as an alternative antioxidant to prevent the decrease in hemoglobin levels of pregnant women. Objective: To determine the effect of giving soursop juice on hemoglobin levels of pregnant white rats with exposure to cigarette smoke. Methods: The experimental laboratory research was designed using the Randomized Post Test Only Control Group Design method. The experimental animal samples were 20 pregnant female Wistar (Rattus norvegicus) rats composed of two control and three treatment groups. Rats were given soursop fruit juice from the first day of rearing until the 18th day of gestation and exposed to cigarette smoke from the 6th day until the 18th. Then blood samples were taken from the mother's heart to measure the hemoglobin level. Results: The results of the hemoglobin level test showed that there was difference between the treatment group and control group. There is an increasing trend from the postitive control group to treatment group. Conclusion: Giving soursop fruit juice can prevent the decrease in hemoglobin levels of pregnant rats exposed to cigarette smoke. Keywords: anemia, free radicals, antioxidants, vitamin C.
Co-Authors Abbas Mahmud Adillah Imansari Adisty Permatasari Afriyadi Ahmad Murajid Ahmad Salim, Ahmad Akmaliza, Anggi Aldiansyah Alem Fawwaz Akbar Alfira Natalia Winda Rahasia Alwi, M. Rasdul AMELIA, NUR Andi Indra Andi Indriani Ibrahim Annisa Arhama Putri Annisatul Syaida Armawati Arsella Indra Lestari Ashriady, Ashriady Aslam Astari, Pocut Astuti, Yayuk Dwi Bakran Budi Rahayu, Budi Bunga Ayu maulida Cut Nurliza Danda Saputra Darmawan, Mhd. Rendi Debi Setiawan Dewi Kartika Dinar, Muhammad Doni Ramadhan, Doni Erdi Fadhilla Marwa Farah Dina, Sari Fikroh Afifi Firly Adistia Fitri Yunita Batubara, Fitri Yunita Fitriani Gunawan Santoso Hadi Sumarsono Hakim, Baihaqy Handayani, Herri Harahap, Nurhidayah Hasibuan, Nur Laila Hayani, Aida hayati , Yati sri Herrin, Paquita Jafier I Wayan Arsana Wiayasa Imansari, Adillah INANNA Iqbal Kartini, Apriyanah KORNELIUS, YOBERTH Kusuma Andriana Listiyani, Ayu M. Zulkarnain Maharani, Dea Mahyunis Mardiana, Ainun Masruroh Rahayu Mauliza, Suci Mohammad Ega Nugraha MUHAMMAD DINAR Muhammad Hasan Muhammad Hasan Muhammad Hasan Muhammad Riswandi Palawa MULYADI MUSTARI Mustika Dewi Muzakkir Muzakkir Muzakkir Nabila Takhira Nabila, Saufi Nadiyatul Haq Lukman Nazirmansyah Nehe, Annisa Shakira Nensy Florence Damanik Nik Mohamad Shakir Bin Nik Yusof Nur Risky Islianti Nurdin Nurdin Nurhaliza Nurjannah Pane, Efi Irwansyah Paulina, Melda Permatasari, Adisti Prastanti, Ryan Hani Praswadi, Hari Purmadana, Eka Putri Ramadhani, Putri Putri Welda Utami Rahma, Indah Rahmadani, Nurul Ramida Raziq, Maulidin Rezeki, R Sri Riswandi Palawa Sabina, Sahnia Sagala, Mahendra Saut Parlindungan Sahara, Aulia Ilma Sandra devi Sandy Kurniawan Saputri, Yuni Sari, Putri Permata Sartika Sari Satriani G Selvi Sulistiani Serly Mustika Sihotang, Azron Muqsitin Sodikin Subandi Subandi Subandi Suhada, Reza Suryani, Linda Susmitra Muhammad Efendi Syafriadi Syamsiatul Akhyar Riyadz Syamsu Rijal Tasya, Puja Islami Telaumbanua, Sadieli Thamrin Thamrin Tahir Titi Rapini, Titi Tondang, Rika sinta Tuti Supatminingsih Vuja Pratiwi Wahyu Agustina, Wahyu Warneri . Wilda Hafny Lubis, Wilda Hafny Windu Baktiyani, Siti Candra Wisnu Barlianto Wito Pirmansyah, Ahmad Yalmi Darma Sela Yohanes Bahari Zulfikar Habibullah, Ahmad