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All Journal Medula Jurnal Ilmu Kedokteran dan Kesehatan Media Pendidikan Matematika JK Unila (Jurnal Kedokteran Universitas Lampung) E-JRM Organisms: Journal of Biosciences AMMA : Jurnal Pengabdian Masyarakat JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Media Pendidikan Matematika
Septiani, Linda
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Diare adalah kondisi yang ditand Ecoli Penyabab Diare Akut : Ecoli Penyabab Diare Akut: Patogenesis, Diagnosis dan Tatalaksana Shinta Dewi, Brigitta; Soleha, Tri Umiana; Septiani, Linda; Apriliana, Ety
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.903

Abstract

The presence of Escherichia coli bacteria or what is often called E.coli is an indicator of contaminated food and water which shows that there is contamination in human feces. 16 Research results show that consuming food contaminated with Escherichia coli bacteria can cause symptoms of diarrhea, pain, fever, and vomiting6. Escherichia coli bacteria can be transmitted through contact with infected food handlers when processing food16. Escherichia coli can be transmitted from feces through contact with human fingers, flies, soil and water that comes into direct contact with food and eating utensils19. Diarrhea in Indonesia is an endemic disease and a potential disease that is associated with a significant mortality rate. In that year, there were 21 extraordinary events (KLB) which spread across 12 provinces and 17 districts/cities. 12. An increase in diarrhea occurred in 2018 with the number of cases reaching 4,504,524 people. In 2019, diarrhea cases decreased slightly to 4,485,513 people. The national incidence rate of diarrhea is 270 per 1,000 population12. In 2020, diarrhea in Bandar Lampung City reached 16,989, in 2021 there was an increase with the number of cases 22,371 (Central Statistics Agency for Bandar Lampung City, 2023) 4. Knowledge and updates regarding E. Coli as a cause of diarrhea are important for medical personnel.
Literature Review: Helminthiasis pada Kehamilan Cahyani, Faradhila Azqiah; Septiani, Linda; Mutiara, Hanna; Suwandi, Jhons Fatriyadi
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.944

Abstract

Helminthiasis is a disease caused by intestinal nematode worms that are transmitted through soil orSoil Transmitted Helminth (STH). The types of STH are:Ascaris lumbricoides, Trichuris trichiura, Ancylostoma duodenale, and Necator americanus. Helminthiasis has infected as many as 1.5 billion of the world's population. Helminthiasis is often found in countries with tropical, subtropical climates and countries that are still categorized as poor. Helminthiasis falls into the categoryNeglected Tropical Disease (NTD) which if left untreated can cause health problems. Purpose ofliterature review This provides a review of the epidemiology, clinical manifestations, necessary examinations, and management of helminthiasis, especially in pregnant women. This research uses a literature study method from 2016-2023. The results of this literature study show that clinical manifestations are influenced by the severity or lightness of the infection, gold standardTo find out the incidence of helminthiasis is to do a stool examination, and helminthiasis can be treated by providing care servicesantenatal care. The conclusion is that helminthiasis in pregnant women can affect the condition of the mother and fetus in the womb.
Faktor-Faktor yang Mempengaruhi Keparahan Derajat Infeksi Dengue pada Pasien Anak Rahel, Clara Arta Uli; Apriliana, Ety; Septiani, Linda; Soleha, Tri Umiana
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.954

Abstract

Dengue infection is an infectious disease transmitted by mosquitoes, especially Aedes species which have been infected to humans. Dengue virus (DENV) consists of four serotypes, namely DEN-1, DEN-2, DEN-3, and DEN-4. Dengue virus infection in humans, especially in pediatric patients, can cause different symptoms from one patient to another. To make it easier to classify the patient's condition, WHO has classified the clinical severity of dengue infection, namely dengue fever, dengue hemorrhagic fever which consists of four levels, and dengue shock syndrome. The varying progression of dengue infection is the basis for knowing the factors that can influence the severity of the degree of dengue infection in terms of the patient's characteristics, clinical symptoms and laboratory results.
Literature Review : Tatalaksana Mioma Uteri Fatahillah, Fatahillah; Hanriko, Rizki; Septiani, Linda; Sari, Ratna Dewi Puspita
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.996

Abstract

Myoma or uterine fibroids are benign tumors that often occur in the uterine wall. Myomas can be asymptomatic or cause symptoms such as abnormal bleeding, pelvic pain, and disorders of the urinary tract. Risk factors include age, race, age of menarche, parity, family history, hormonal contraceptive use, and obesity. Diagnostic examination involves pelvic examination, ultrasound, hysteroscopy, and MRI. Medical therapies used such as NSAIDs, oral contraceptives, Levonorgestrel-releasing intrauterine system (Mirena), tranexamic acid (cyclocapron), GnRH agonists and SPRMs and surgeries such as myomectomy, hysterectomy, uterine artery embolization, and MRgFUS. Management of Myoma must consider various factors, namely tumor size, patient age, symptom and the desire to maintain fertility in order to provide optimal treatment according to the patient's needs and preferences.
Gangguan Siklus Menstruasi Alghani, Sulthan Rafi; Sari, Ratna Dewi Puspita; Septiani, Linda; Utama, Winda Trijayanthi
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.1048

Abstract

The female reproductive system undergoes regular cycles in preparation for pregnancy and fertilization, known as the menstrual cycle. This cycle involves hormonal changes and complex physiological processes, with the follicular phase dominated by estrogen and the luteal phase dominated by progesterone. Menstrual cycle disorders, such as amenorrhea, polymenorrhea, and oligomenorrhea, can be caused by various factors including hormonal imbalances, unhealthy lifestyles, and certain medical conditions. Management of menstrual disorders varies depending on their causes, which may require a holistic and individualized approach. A good understanding of the menstrual cycle and its disorders is crucial for accurate diagnosis and appropriate treatment. It is also important to promote overall women's reproductive health.
Characteristics of Thyroid Carcinoma Patients at Dr. H. Abdul Moeloek Hospital for the Period of January 2023 – August 2024 Qurani, Istiqomatul; Septiani, Linda; Kurniati, Intanri; Windarti, Indri
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1333

Abstract

Thyroid carcinoma is the most common cancer found in the endocrine system that arises from thyroid parenchymal cells.  Its prevalence has increased over the past few decades with a mortality rate of 0.5% per 100,000 cases. The incidence of thyroid carcinoma in 2020 ranks 7th in the world as the 9th most frequent incidence occurs from all types of cancer. Objective: This study aims to determine the characteristics of thyroid carcinoma patients at Dr. H. Abdul Moeloek Regional General Hospital for the period of January 2023 – August 2024. Method: This study used a descriptive observational design and Total Sampling technique with a data source in the form of secondary data on medical records from 82 thyroid carcinoma patients at the Dr. H. Abdul Moeloek Regional General Hospital for the period January 2023 to August 2024.  Results: In this study, thyroid carcinoma patients were mostly female, with an age group in the range of 41-60 years. The most common type of thyroid carcinoma is papillary carcinoma and the least common type is anaplastic carcinoma. Conclusion: In this study, the characteristics of thyroid carcinoma patients were obtained based on gender, age group, and type of histopathological diagnosis.
Infeksi Protozoa Usus dan Anemia Sebagai Ancaman Kesehatan Global: Literature Review Rahmah, Nisrina Nur; Mutiara, Hanna; Septiani, Linda; Himayani, Rani
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1291

Abstract

Intestinal protozoan infections are a global health issue that needs to be monitored due to the high morbidity and mortality rates, particularly in areas with poor hygiene and sanitation. Intestinal protozoan infections are diseases caused by protozoan parasites, which are single-celled eukaryotic microorganisms generally classified under the Kingdom Protista. The most frequently reported intestinal protozoa species responsible for human infections are Blastocystis hominis, Cryptosporidium parvum, and Giardia lamblia. There are two key factors contributing to the occurrence of intestinal protozoan infections: individual and environmental factors. Intestinal protozoan infections are known to cause various harmful consequences, particularly regarding the nutritional status of the affected individuals. As a result, intestinal protozoan infections are often associated with iron deficiency anemia, which can ultimately disrupt growth and development in children and decrease productivity in adults. This study aims to identify the pathways through which intestinal protozoan infections cause iron deficiency anemia. The study method involved a literature review and problem analysis. The results indicate that there are three main pathways through which intestinal protozoan infections lead to iron deficiency anemia: the metabolism of pathogenic microorganisms within the human body, the activation of the immune response to pathogenic microorganisms, and the reduction in micronutrient levels. To prevent these infections, the public is advised to improve personal hygiene, such as regularly washing hands, and to enhance environmental sanitation by treating water through filtration or disinfection.
Diagnosis dan Penatalaksanaan Trigeminal Neuralgia Zefanya, Ezekial; Berawi, Khairun Nisa; Septiani, Linda; Wardani, Dyah Wulan Sumekar Rengganis
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1411

Abstract

Trigeminal Neuralgia (TN) is a sudden pain in the facial area, short duration for about one second to two minutes, being-stabbed feels like, and occurs repeatedly in one or more branches of the trigeminal nerve. Type 1 (one) as intermittent pain and type 2 (two) as constant pain with different clinical, pathological, and prognostic complaints. The causes of Trigeminal Neuralgia involve peripheral pathology in the roots (compression or traction), brainstem dysfunction, basal ganglia, and cortical pain modulation mechanisms, but the most common is due to neurovascular factors. The diagnosis of Trigeminal Neuralgia is basically clinical, to rule out secondary causes, detect pathological changes in the affected roots and neurovascular compression (NPC), Magnetic Resonance Imaging (MRI) may be used. The choice of first-line drug therapy is carbamazepine, and for the second line patient may use oxcarbazepine, baclofen, lamotrigine, phenytoin, and topiramate. Microvascular decompression (MVD) is the surgical treatment of choice for TN that is resistant to medical management. Patients with significant medical comorbidities, without neurovascular compression and multiple sclerosis are generally advised to undergo gamma knife radiosurgery, percutaneous balloon compression, glycerol rhizotomy, and radiofrequency thermocoagulation procedures. The most effective medical therapy is with carbamazepine with a reported reduction in facial pain after taking it as much as 47 percent. For patients who do not respond to medical treatment, microvascular decompression surgery is performed with an effectiveness rate in patients as much as 90 percent.
Glasgow Coma Scale: Tinjauan terhadap Kegunaan, Keterbatasan, dan Perkembangannya Aquila Graham; Setiorini, Anggi; Septiani, Linda; Perdani, Roro Rukmi Windi
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1396

Abstract

The Glasgow Coma Scale (GCS) is a widely used neurological assessment tool for evaluating the level of consciousness in patients with brain injury. Introduced in 1974 by Teasdale and Jennett, it has become a standard in emergency departments, intensive care units, and neurosurgical wards worldwide. The GCS assesses patient responses in three domains: eye opening, verbal response, and motor response, with scores ranging from 3 (deep coma) to 15 (fully conscious). The GCS score is used to classify the severity of Traumatic Brain Injury (TBI) and predict clinical outcomes. However, several studies have highlighted limitations of the GCS, particularly in predicting patient outcomes and its application in specific populations. This article provides a critical review of the GCS, including its utility, limitations, and ongoing modifications and developments.
Tinjauan Pustaka : Kebiasaan Merokok dan Paparan Ultraviolet Sebagai Faktor Risiko Katarak Senilis Ghaitsa Lulua; Himayani, Rani; Septiani, Linda; Berawi, Khairunnisa
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1419

Abstract

Cataract ranks second as the most common visual impairment and first as a cause of blindness, as the lens hardens and causes a decrease in sharp vision. Based on age, cataracts are divided into several types: congenital cataract, juvenile cataract and senile cataract. Senile cataract is a cataract that often occurs in older people. The classification of senile cataracts is based on the progression of the cataract's opacity, namely, incipient, immature, mature, and hypermature. Some of the risk factors for senile cataracts include a history of diabetes mellitus, family history, smoking, and exposure to ultraviolet light. Smokers have a higher risk of developing senile cataracts than non-smokers. Ingredients in cigarettes such as cyanate, nicotine and tar can cause changes and denaturation of proteins in the lens of the eye. Meanwhile, sunlight absorbed by the eye produces free radicals and affects the tissues in the lens of the eye, triggering oxidative reactions, causing changes in amino acid reactions and leading to senile cataracts.
Co-Authors Adisa, Mutiara Putri Afriyani, Afriyani Alghani, Sulthan Rafi Ambarwati, Yuli Ananta, Yoga Andrifianie, Femmy Angga Wijaya, Angga Annasya, Benazhir Saninah Aquila Graham Ari Wahyuni Aslina, Enna Cahyani, Faradhila Azqiah Damayanti, Ervina Dwi Budi Santoso Dyah Wulan Sumekar Rengganis Wardani Endah Setyaningrum, Endah Ety Apriliana Fatahillah, Fatahillah Ghaitsa Lulua Ginting, Bisart Hanna Mutiara, Hanna Happy, Terza Aflika Hendri Busman Heni Pujiastuti Idris, Mohamad Indri Windarti Intan Kusumaningtyas Intanri Kurniati Jhons Fatriyadi Suwandi Kanedi, M. Kanedi, Muhammad Khairun Nisa Lusina, Septia Eva Marcelia, Selvi Marcellia, Selvi Masherni, Erniza Muhammad Ricky Ramadhian Mulya, Ireniza Pradevi Mumtazah, Dzul Fithria Nuning Nurcahyani Nur Diana Oktavia Ningtias, Nabila Primasari Pertiwi Qanita Arindia, Naifa Hana Qurani, Istiqomatul Rahel, Clara Arta Uli Rahmah, Nisrina Nur Rahmawati, Rahmawati Ramadhana Komala Ramdini, Dwi Aulia Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Ratna, Maya Ganda Rika Lisiswanti Risti Graharti Rizki Hanriko Roro Rukmi Windi Perdani, Roro Rukmi Rosa, Emantis Septia Eva Lusina Setiawan, Gigih Setiorini, Anggi Shinta Dewi, Brigitta Sinaga, Herman Fransiskus Sofyan Musyabiq Wijaya Suryadi Islami Susianti, Susianti Sutarto . SYAIFUL BAHRI Syazili Mustofa Tri Umiana Soleha Winda Trijayanthi Utama, Winda Trijayanthi Wiwi Febriani Yulianti Zefanya, Ezekial