Articles
Hubungan Kadar Kreatinin Dengan Hemoglobin Pada Pasien Gagal Ginjal Kronik Sebagai Rujukan Terapi Erythropoietin (EPO)
Tandi Manu, Thomas;
Zaena Safitri, Trysia;
Urip, Urip;
Pauzi, Iswari;
Khusuma, Ari
Indonesian Health Issue Vol. 4 No. 2 (2025): AGUSTUS
Publisher : Indonesian Journal Publisher
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DOI: 10.47134/inhis.v4i2.132
Background: Chronic kidney disease (CKD) is a common condition and a global health problem with various causes that lead to a gradual decline in kidney function, resulting in increased creatinine levels. This condition reduces the production of the hormone erythropoietin (EPO), which stimulates the bone marrow to produce red blood cells, leading to decreased hemoglobin levels and resulting in anemia. Erythropoietin (EPO) therapy represents a primary therapeutic option for the management of anemia in patients with chronic kidney disease (CKD) PurposeTo determine the relationship between creatinine and hemoglobin levels in chronic kidney disease patients as a reference for erythropoietin (EPO) therapy. Methods: This study employed an analytical observational method with a cross-sectional approach by reviewing medical record data. The sample consisted of 56 patients obtained through total sampling. The data were analyzed using the Pearson correlation test. Results: The average creatinine level was 9.92 mg/dL, and the average hemoglobin (Hb) level was 7.96 g/dL. Pearson correlation analysis between creatinine and hemoglobin levels in patients receiving erythropoietin (EPO) therapy showed a statistically significant result with a p-value of 0.001 (<0.05) and a moderate negative correlation (r = -0.436). Conclusion: A significant negative correlation was found between creatinine and hemoglobin levels in patients undergoing EPO therapy, indicating that higher creatinine levels tend to be associated with lower hemoglobin concentrations.
The Effect Of Duration Of Tuak Consumption On Low Density Lipoprotein (LDL) And Triglyceride (TG) Levels In The Community In Taman Bali Village
Manu, Thomas Tandi;
Ananda, Dewa Ayu Putu Wiweka;
Getas, I Wayan;
Wiadnya, Ida Bagus Rai;
Khusuma, Ari
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram
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DOI: 10.32807/jambs.v12i2.544
Tuak is a traditional alcoholic drink made from palm sap. Excessive alcohol consumption over a long period of time can affect lipid metabolism, increasing LDL and Triglyceride levels in the blood. Increased levels can cause cardiovascular disease. To determine the effect of the duration of tuak consumption on LDL and Triglyceride levels in the community in Dusun Taman Bali. The research used is Observational Analytical with a cross-sectional approach. The sample in this study was the community in Dusun Taman Bali who consumed Tuak for 1, 3, and 5 years with a total of 30 respondents using One Way Anova data analysis. The average LDL levels of 30 respondents with an average of 117.20 mg/dL consumed tuak for 1 year, 130.30 mg/dL for 3 years and 151.20 mg/dL for 5 years, while the average Triglyceride levels of 30 respondents who consumed Tuak for 1 year were 160.90 mg/dL, 166.60 mg/dL for 3 years and 201.10 mg/dL for 5 years. The results obtained showed a significant value of LDL levels of 0.000 while Triglyceride levels were 0.022. This means P <0.05, which means that there is an effect of the duration of tuak consumption of 1.3 and 5 years on LDL and Triglyceride levels in the community in Dusun Taman Bali.
Bacterial Contamination Analysis Based On Total Plate Count From Various Uses Of Compact Powder
Putri, Ni Putu Sintyani;
Kristinawati, Erna;
Khusuma, Ari
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram
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DOI: 10.32807/jambs.v12i2.470
The repeated and alternating use of compact powder can increase the risk of bacterical contamination. This contamination can be harmful to the skin health of the users, especially if the compact powder used has been contamination with bacteria exceeding the standard limit set by BPOM, which is 5 × 10³ colonies/g or colonies/mL. Therefore, an analysis of bacterial contamination in the repeatedly and alternately used sompact powder from various uses is necessary using the Total Plate Cound (TPC) method to ensure the suitability and safety of the compact powder. The objective is to determine the level of bacterial contamination based on the Total Plate Cound (TPC) on compact powder used by makeup artists, tester from cosmetic stores, personal use dan new product. The samples of conpact powder analyzed amounted to 24 samples, using purposive sampling technique and the data was analyzed descriptively. The result obtained from the calculation of the average number of bacterical colonies in personal use compact powder, new product and tester from each cosmetic store are < 3 x 10¹ CFU/g, while the average for compact powders sourced from makeup artists is 1.66 x 10^5 CFU/g. Compact powder derived from personal use, new products, and those used as testers by cosmetic stores show ALT values that still fall within the category of meeting the standards set by BPOM. Meanwhile, compact powder derived from makeup artists shows ALT values that exceed the standards set by BPOM.
Long Suffering Type 1 Diabetes Mellitus During Metabolic Acidosis on Positiveness of Ketones in Urine Patients
Mahayani, I Gusti Ayu Putu Sachita;
Urip, Urip;
Khusuma, Ari;
Pauzi, Iswari
THRIVE Health Science Journal Vol. 1 No. 1 (2024): March
Publisher : Balai Publikasi Indonesia
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DOI: 10.56566/thrive.v1i1.89
Examination of ketones in the patient's urine and measuring the patient's blood sugar level will determine whether there will be metabolic acidosis in patients with type 1 diabetes mellitus, which is a metabolic disorder that can be caused by various etiologies, such as chronic hyperglycemia due to impaired insulin secretion or impaired insulin action. alone. Diabetes Mellitus type 1 itself is more caused by reduced insulin secretion due to damage to pancreatic -cells. This study was conducted to examine ketones in urine on the duration of suffering from type 1 diabetes mellitus when metabolic acidosis occurs Data collection in this study was carried out by accidental sampling method by researchers to collect secondary and primary data on urine ketones in patients with metabolic acidosis. Based on research that has been done, data obtained from 34 patients with type 1 diabetes mellitus at the Sigerongan Health Center, as many as 8 patients with positive results of urine ketones with a prevalence of +2 totaling 3 people and +3 totaling 5 people. Judging from the high level of glucose (hyperglycemia) that is > 200 mg/dl and the positivity of ketone bodies in the patient's urine as a sign of metabolic acidosis. With a long-susceptibility to suffer from diabetes mellitus 1-5 years and above. The results of measuring ketone levels in the patient's urine show that there is no relationship with the duration of suffering from diabetes mellitus in the urine but blood sugar levels.
Differences in Cholesterol Levels in Coffee Drinkers Without Sugar and Coffee Drinkers With Sugar in The Work Area
Salsabila, Nadira;
Khusuma, Ari;
Jiwintarum, Yunan
THRIVE Health Science Journal Vol. 1 No. 1 (2024): March
Publisher : Balai Publikasi Indonesia
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DOI: 10.56566/thrive.v1i1.93
Indonesia is one of the coffee-producing countries as well as coffee bean exporters which ranks fourth in the world. Coffee is one of the most consumed beverages in the world which has become a major need for people without realizing it. Based on the results of previous studies that coffee drinkers using sugar can increase cholesterol levels. Excessive cholesterol in the body will accumulate in the walls of blood vessels and cause a condition called atherosclerosis, namely narrowing or hardening of the arteries. This condition is the forerunner of heart disease and stroke. This study aims to determine differences in cholesterol levels in coffee drinkers without sugar and coffee drinkers using sugar in the working area of Karang Pule. This research is an analytical observation using capillary blood samples of respondents who drink coffee without sugar and drink coffee with sugar. The data obtained in this study were recorded and presented in tabular form and analyzed descriptively. From the results of the study, it was found that the results of examining cholesterol levels in coffee drinkers without sugar were 15 people with an average cholesterol level of 169 mg/dl. Meanwhile, coffee drinkers using sugar were 15 people with an average cholesterol level examination of 242 mg/dl
Perbedaan Jumlah Limfosit dan Monosit serta Morfologi Eritrosit pada Perokok Tembakau dan Elektrik sebagai Faktor Risiko Aterosklerosis pada Remaja
Laila Nisa, Isra;
Rohmi;
Khusuma, Ari;
Zaetun, Siti
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram
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DOI: 10.32807/jilts.v3i1.60
Background : Smoking from adolescence can increase the risk of atherosclerosis because there is a buildup of fibrolipids and other substances in the blood that can cause plaque. Meanwhile, research results show that e-cigarettes are no less dangerous than tobacco cigarettes. Namely, the number of lymphocytes in e-smokers is 54% and tobacco smokers are 39% (Mega, 2020). The novelty of this research is to look at differences in erythrocyte count and morphology in adolescents at risk of atherosclerosis. Research Objectives : To determine the differences in the number of lymphocytes and monocytes and the morphology of erythrocytes in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents. Research Methods : This research is an analytical observational study with a cross sectional research design and uses the lameshow formula to determine the sample size so that a sample size of 30 samples can be obtained. Data were tested using the Independent T-test and Mann Whitney-U test. The results of the study : The average percentage of lymphocytes and monocytes in tobacco and electronic smoker is 37% & 27% lymphocytes and 7% & 6% monocytes. From 15 samples of tobacco smokers the results were normal and from 15 samples of e-smokers there was 1 lymphocyte result below normal. Also, the abnormal cells found include anulocytes, tear drops, burr cells, ovalocytes and stomatocytes. Conclusion : There are differences in the number of lymphocytes and monocytes as well as erythrocyte morphology in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents with the probability value for lymphocytes being 0.01<0.05 and monocytes 0.04<0.05.
Identifikasi Sel Ragi (Candida sp.) pada Sedimen Urine dengan Menggunaka Metode Preparat Basah dan Preparat Gram pada Penderita Diabetes Melitus
Cahayaningrum, Aryani;
Agrijanti;
Manu, Thomas Tandi;
Khusuma, Ari
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram
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DOI: 10.32807/jilts.v3i1.75
Latar Belakang: Kandidiasis adalah infeksi jamur yang disebabkan oleh jamur Candida sp. Diabetes melitus menjadi salah satu faktor predisposisi terjadinya infeksi jamur. Diagnosa dari kandidiasis bisa dilakukan dengan berbagai macam cara. Salah satunya adalah dengan melihat sel ragi pada sedimen urin di bawah mikroskop dengan menggunakan metode preparat basah atau melakukan pewarnaan gram . Tujuan Penelitian: Mengidentifikasi sel ragi (Candida sp.) pada sedimen urin dengan menggunakan metode preparat basah dan preparat gram pada penderita Diabetes Melitus. Metode Penelitian: Rancangan Penelitian ini merupakan penelitian deskriptif, yang dilakukan dengan metode observasional analitik dengan pendekatan cross sectional sehingga variabel bebas dan variabel terikat diamati dalam satu waktu. Hasil: Didapatkan 8 sampel positif sel ragi dan 14 sampel negatif sel ragi pada metode preparat basah dan preparat gram. Kesimpulan: Berdasarkan kualitas, preparat gram lebih unggul daripada preparat basah karena sel ragi yang terlihat pada preparat gram lebih jelas daripada sel ragi yang terlihat pada preparat gram. Sedangkan dari segi efisensi waktu dan biaya, preparat basah lebih unggul karena cepat dan murah.
Odds Ratio of Increase in Hemoglobin Level Associated with Consumption of Songgak Coffee in Patients with Pulmonary TB
Dewi, Lale Budi Kusuma;
Hartuti, Sri;
Getas, I Wayan;
Agrijanti, Agrijanti;
Tatontos, Erlin Yustin;
Wiadnya, Ida Bagus Rai;
Zaetun, Siti;
Khusuma, Ari
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan
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Pulmonary TB cases in Indonesia are the second highest in the world. The incidence of Anemia in pulmonary TB patients can be as high as 90%. Anemia can lead to poor outcomes in the recovery of pulmonary TB. Songgak coffee is a coffee with a mixture of spices that is commonly consumed by the people of Central Lombok to make the body healthy and increase vitality, including pulmonary TB patients. Songgak coffee is made from 7 types of spices mixed with coffee. The results of previous research show that Songgak coffee has quite good antioxidant content and is an immunostimulant. Antioxidants may increase Hemoglobin levels. This was a case-control study. A total of 26 new pulmonary TB patients were divided into 2 groups. Group A received songgak coffee as an additional anti-TB drug, while group B received anti-TB drug therapy alone. Hemoglobin levels in groups A and B were measured before drug administration and 14 days after treatment. The data collected were nominal data, reported as increasing and non-increasing. A total of 12 out of 13 patients in group A had an increase in Hemoglobin, while only 1 person in group B had an increase in Hemoglobin. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who consume songgak is 12. The odds ratio value for increasing Hemoglobin in pulmonary TB patients taking songgak is 12. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who take Songgak is 12 times higher than in pulmonary TB patients who do not take Songgak.
PENGARUH PERBEDAAN LOKASI PEMBERIAN KOMPRES HANGAT (AXILLA&TEMPORAL) TERHADAP PENURUNAN SUHU PADA ANAK YANG MENGALAMI DEMAM DI RSUD AHMAD YANI KOTA METRO TAHUN 2024
Agata, Annisa;
Japlani, Vida Lia;
Anita, Fitri;
Khusuma, Ari
Jurnal Ilmiah Kesehatan Media Husada Vol 14 No 2 (2025): November
Publisher : LPPMK STIKES Widyagama Husada
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DOI: 10.33475/jikmh.v14i2.432
Abstak: Demam (pireksia) merupakan keadaan suhu tubuh di atas normal sebagai akibat peningkatan pusat pengatur suhu di hipotalamus. Demam yang terlalu tinggi dapat menimbulkan masalah yang serius pada anak. Jika sampai timbul kejang demam dapat berdampak pada kelainan neurologis hingga risiko epilepsi saat dewasa. Pemilihan lokasi kompres hangat dapat memaksimalkan penatalaksanaan demam secara efektif. Tujuan penelitian untuk mengetahui pengaruh perbedaan lokasi pemberian kompres hangat (axilla & temporal) terhadap penurunan suhu pada anak yang mengalami demam. Rancangan penelitian yaitu quasi eksperiment design menggunakan non equivalent control group. Populasi adalah seluruh anak usia 1-14 tahun yang mengalami demam, dengan jumlah sampel penelitian sebanyak 36 orang, menggunakan teknik purposive sampling. Analisis bivariat menggunakan analisis uji T. Hasil analisis univariat diperoleh bahwa rata-rata suhu anak sebelum dilakukan kompres hangat di axilla yaitu 38,239oC dan setelah kompres menjadi 37,173oC. Rata-rata suhu anak sebelum dilakukan kompres hangat di temporal yaitu 38,094 oC dan setelah kompres menjadi 37,583 oC. Hasil analisis bivariat diperoleh ada pengaruh kompres hangat area axilla terhadap suhu tubuh pada anak demam (p-value=0,000). Terdapat pengaruh kompres hangat area temporal terhadap suhu tubuh pada anak demam (p-value=0,000). Ada perbedaan pengaruh perbedaan lokasi pemberian kompres hangat antara axilla & temporal terhadap penurunan suhu pada anak yang mengalami demam (p-value= 0,000 (p-value< α (0,05)). Saran bagi perawat agar dapat mengimplementasikan teknik kompres hangat dengan mempertimbangkan efektivitas kompres hangat di area axilla. Kata Kunci: Demam; kompres hangat; axilla & temporal.
Card Bloodless : Inovasi Alat Ukur Kolesterol Non – Invasive Deteksi Dini Kadar Kolesterol dengan Pengaplikasian Arduino Uno
Dharmajaya Gisu, I Ketut Budi;
Lalu Srigede;
Yudha Anggit Jiwantoro;
Ari Khusuma
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 2 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram
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DOI: 10.32807/jilts.v4i2.193
Latar Belakang: Kadar Kolesterol tinggi merupakan salah satu faktor utama yang menyebabkan penyakit henti jantung atau serangan jantung dan stroke yang merupakan penyebab kematian tertinggi di seluruh dunia. Kolesterol merupakan zat yang dibutuhkan oleh tubuh, tetapi jika kadar Kolesterol tidak sesuai dengan nilai normal yang ada, maka zat ini akan menimbulkan berbagai macam penyakit. Identifikasi dan pemantauan kadar kolesterol menjadi hal kritis dalam upaya pencegahan penyakit. Kolesterol umumnya dapat di pantau dengan menggunakan alat – alat Kesehatan dengan metode invasive yang mengharuskan pasien datang ke fasilitas layanan Kesehatan. Dengan metode invasive tidak jarang terjadi human error yang menyebabkan kesalahan atau trauma luka pada pasien. Hal ini yang menjadi alasan peneliti untuk mengembangkan inovasi alat ukur kadar kolesterol dengan metode non – invasive sebagai alternatif pemeriksaan yang tidak menimbulkan trauma luka pada pasien. Tujuan Penelitian: Penelitian ini bertujuan untuk mengembangkan alat ukur kadar kolesterol dengan metode non – invasive dengan menggunakan Arduino Uno dan TCRT5000 yang dapat meniadakan trauma luka pada pasien saat pemeriksaan. Metode Penelitian: Metode dalam penelitian ini menggunakan metode Research and Development, peneliti melakukan uji kelayakan Card Bloodless kepada 15 pasien dengan perbandingan POCT sebagai control. Hasil Penelitian: Berdasarkan data yang diperoleh, Card Bloodless dapat melakukan uji kadar kolesterol tanpa menimbulkan trauma pada pasien. Kesimpulan: Berdasarkan penelitian diatas dapat disimpulkan bahwa alat Card Bloodless dapat dijadikan sebagai alat konvensional yang memiliki nilai akurasi dan presisi yang hampir sama dengan alat konvensional lain dengan keunggulan tanpa harus menggunakan sampel darah yaitu dengan metode Non – Invasive.