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Perbedaan Jumlah Limfosit dan Monosit serta Morfologi Eritrosit pada Perokok Tembakau dan Elektrik sebagai Faktor Risiko Aterosklerosis pada Remaja Laila Nisa, Isra; Rohmi; Khusuma, Ari; Zaetun, Siti
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.60

Abstract

Background : Smoking from adolescence can increase the risk of atherosclerosis because there is a buildup of fibrolipids and other substances in the blood that can cause plaque. Meanwhile, research results show that e-cigarettes are no less dangerous than tobacco cigarettes. Namely, the number of lymphocytes in e-smokers is 54% and tobacco smokers are 39% (Mega, 2020). The novelty of this research is to look at differences in erythrocyte count and morphology in adolescents at risk of atherosclerosis. Research Objectives : To determine the differences in the number of lymphocytes and monocytes and the morphology of erythrocytes in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents. Research Methods : This research is an analytical observational study with a cross sectional research design and uses the lameshow formula to determine the sample size so that a sample size of 30 samples can be obtained. Data were tested using the Independent T-test and Mann Whitney-U test. The results of the study : The average percentage of lymphocytes and monocytes in tobacco and electronic smoker is 37% & 27% lymphocytes and 7% & 6% monocytes. From 15 samples of tobacco smokers the results were normal and from 15 samples of e-smokers there was 1 lymphocyte result below normal. Also, the abnormal cells found include anulocytes, tear drops, burr cells, ovalocytes and stomatocytes. Conclusion : There are differences in the number of lymphocytes and monocytes as well as erythrocyte morphology in tobacco and electronic smokers as risk factors for atherosclerosis in adolescents with the probability value for lymphocytes being 0.01<0.05 and monocytes 0.04<0.05.
Identifikasi Sel Ragi (Candida sp.) pada Sedimen Urine dengan Menggunaka Metode Preparat Basah dan Preparat Gram pada Penderita Diabetes Melitus Cahayaningrum, Aryani; Agrijanti; Manu, Thomas Tandi; Khusuma, Ari
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.75

Abstract

Latar Belakang: Kandidiasis adalah infeksi jamur yang disebabkan oleh jamur Candida sp. Diabetes melitus menjadi salah satu faktor predisposisi terjadinya infeksi jamur. Diagnosa dari kandidiasis bisa dilakukan dengan berbagai macam cara. Salah satunya adalah dengan melihat sel ragi pada sedimen urin di bawah mikroskop dengan menggunakan metode preparat basah atau melakukan pewarnaan gram . Tujuan Penelitian: Mengidentifikasi sel ragi (Candida sp.) pada sedimen urin dengan menggunakan metode preparat basah dan preparat gram pada penderita Diabetes Melitus. Metode Penelitian: Rancangan Penelitian ini merupakan penelitian deskriptif, yang dilakukan dengan metode observasional analitik dengan pendekatan cross sectional sehingga variabel bebas dan variabel terikat diamati dalam satu waktu. Hasil: Didapatkan 8 sampel positif sel ragi dan 14 sampel negatif sel ragi pada metode preparat basah dan preparat gram. Kesimpulan: Berdasarkan kualitas, preparat gram lebih unggul daripada preparat basah karena sel ragi yang terlihat pada preparat gram lebih jelas daripada sel ragi yang terlihat pada preparat gram. Sedangkan dari segi efisensi waktu dan biaya, preparat basah lebih unggul karena cepat dan murah.
Odds Ratio of Increase in Hemoglobin Level Associated with Consumption of Songgak Coffee in Patients with Pulmonary TB Dewi, Lale Budi Kusuma; Hartuti, Sri; Getas, I Wayan; Agrijanti, Agrijanti; Tatontos, Erlin Yustin; Wiadnya, Ida Bagus Rai; Zaetun, Siti; Khusuma, Ari
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Pulmonary TB cases in Indonesia are the second highest in the world. The incidence of Anemia in pulmonary TB patients can be as high as 90%. Anemia can lead to poor outcomes in the recovery of pulmonary TB. Songgak coffee is a coffee with a mixture of spices that is commonly consumed by the people of Central Lombok to make the body healthy and increase vitality, including pulmonary TB patients. Songgak coffee is made from 7 types of spices mixed with coffee. The results of previous research show that Songgak coffee has quite good antioxidant content and is an immunostimulant. Antioxidants may increase Hemoglobin levels. This was a case-control study. A total of 26 new pulmonary TB patients were divided into 2 groups. Group A received songgak coffee as an additional anti-TB drug, while group B received anti-TB drug therapy alone. Hemoglobin levels in groups A and B were measured before drug administration and 14 days after treatment. The data collected were nominal data, reported as increasing and non-increasing. A total of 12 out of 13 patients in group A had an increase in Hemoglobin, while only 1 person in group B had an increase in Hemoglobin. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who consume songgak is 12. The odds ratio value for increasing Hemoglobin in pulmonary TB patients taking songgak is 12. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who take Songgak is 12 times higher than in pulmonary TB patients who do not take Songgak.
PENGARUH PERBEDAAN LOKASI PEMBERIAN KOMPRES HANGAT (AXILLA&TEMPORAL) TERHADAP PENURUNAN SUHU PADA ANAK YANG MENGALAMI DEMAM DI RSUD AHMAD YANI KOTA METRO TAHUN 2024 Agata, Annisa; Japlani, Vida Lia; Anita, Fitri; Khusuma, Ari
Jurnal Ilmiah Kesehatan Media Husada Vol 14 No 2 (2025): November
Publisher : LPPMK STIKES Widyagama Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/jikmh.v14i2.432

Abstract

Abstak: Demam (pireksia) merupakan keadaan suhu tubuh di atas normal sebagai akibat peningkatan pusat pengatur suhu di hipotalamus. Demam yang terlalu tinggi dapat menimbulkan masalah yang serius pada anak. Jika sampai timbul kejang demam dapat berdampak pada kelainan neurologis hingga risiko epilepsi saat dewasa. Pemilihan lokasi kompres hangat dapat memaksimalkan penatalaksanaan demam secara efektif. Tujuan penelitian untuk mengetahui pengaruh perbedaan lokasi pemberian kompres hangat (axilla & temporal) terhadap penurunan suhu pada anak yang mengalami demam. Rancangan penelitian yaitu quasi eksperiment design menggunakan non equivalent control group. Populasi adalah seluruh anak usia 1-14 tahun yang mengalami demam, dengan jumlah sampel penelitian sebanyak 36 orang, menggunakan teknik purposive sampling. Analisis bivariat menggunakan analisis uji T. Hasil analisis univariat diperoleh bahwa rata-rata suhu anak sebelum dilakukan kompres hangat di axilla yaitu 38,239oC dan setelah kompres menjadi 37,173oC. Rata-rata suhu anak sebelum dilakukan kompres hangat di temporal yaitu 38,094 oC dan setelah kompres menjadi 37,583 oC. Hasil analisis bivariat diperoleh ada pengaruh kompres hangat area axilla terhadap suhu tubuh pada anak demam (p-value=0,000). Terdapat pengaruh kompres hangat area temporal terhadap suhu tubuh pada anak demam (p-value=0,000). Ada perbedaan pengaruh perbedaan lokasi pemberian kompres hangat antara axilla & temporal terhadap penurunan suhu pada anak yang mengalami demam (p-value= 0,000 (p-value< α (0,05)). Saran bagi perawat agar dapat mengimplementasikan teknik kompres hangat dengan mempertimbangkan efektivitas kompres hangat di area axilla. Kata Kunci: Demam; kompres hangat; axilla & temporal.
Investigating the Phytochemical Composition, GCMS Profile and Antimicrobial Effects of Nursehan Herbal Remedy for Sinusitis in Praya, Central Lombok Agrijanti; Kusumadewi, Lale Budi; Khusuma, Ari; Djannah, Fathul; Aini, Siti Rahmatul
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November: In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.11125

Abstract

Recent studies emphasize the importance of medicinal plants in Indonesia's healthcare systems, where traditional remedies, including herbal formulations, are commonly used for treating ailments such as sinusitis. This research focuses on the Nursehan herbal remedy, a traditional treatment for sinusitis, used in Praya District, Central Lombok Regency. Nursehan is a combination of several plant materials, including Cinnamomum verum, Nauclea orientalis, and Nigella sativa, which are believed to alleviate sinus-related symptoms. However, scientific evidence supporting its efficacy remains limited. This study aims to validate the antimicrobial potential of Nursehan by analyzing its phytochemical profile and antibacterial activity. The Nursehan extract was prepared using a maceration method, and its chemical composition was assessed via GC-MS analysis, which identified key bioactive compounds such as hexadecanoic acid and 8-heptadecenoic acid, known for their antimicrobial and anti-inflammatory properties. Antimicrobial testing using the Kirby-Bauer method revealed significant antibacterial activity, particularly against Streptococcus pyogenes and Staphylococcus aureus. These findings provide scientific backing for the traditional use of Nursehan and highlight its potential as a therapeutic agent for sinusitis.