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Penyuluhan Bahaya Hiperurisemia dan Pemanfaatan Jamu Herbal Songgak bagi Penderita Hypeurisemia di Tanjung Karang Mataram Nusa Tenggara Barat Khusuma, Ari; Kusuma Dewi, Lale Budi; Agrijanti, Agrijanti
Jurnal Indonesia Mengabdi Vol. 7 No. 1 (2025): June Edition
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) STKIP Nurul Huda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30599/whr4se09

Abstract

Skrining penyakit tidak menular (PTM) seperti hiperurisemia memerlukan partisipasi berbagai pihak. Namun, masyarakat sering enggan melakukan skrining, meski data Puskesmas Tanjung Karang tahun 2021 menunjukkan hiperurisemia sebagai salah satu dari tiga penyakit terbanyak. Masyarakat cenderung mengandalkan obat-obatan untuk terapi gout, meskipun terapi non-farmakologi juga efektif. Penelitian tahun 2021 menunjukkan herbal tradisional Sasak, songgak, dapat menurunkan kadar gula darah pada tikus, dan penelitian 2022 membuktikan efektivitasnya dalam menurunkan kadar asam urat darah tikus. Kegiatan pengabdian ini bertujuan mengendalikan kadar asam urat penderita hiperurisemia dengan songgak. Dari 30 peserta, 25 mengalami penurunan kadar asam urat dari rata-rata 8,98 mg/dL menjadi 6,52 mg/dL. Lima peserta tidak melanjutkan konsumsi karena alasan kesehatan. Mahasiswa berperan aktif dalam pelaksanaan dan evaluasi kegiatan, sekaligus mempromosikan songgak sebagai jamu herbal tradisional Lombok, mendukung upaya prioritas Kementerian Kesehatan dalam pengendalian PTM.  
Hubungan Hasil Pemeriksaan Kultur Urin terhadap Hasil Protein dan Berat Jenis Urin sebagai Pemeriksaan Fungsi Ginjal pada Pasien Infeksi Saluran Kemih Supriyanti, Ispi; Agrijanti; Ari Khusuma; Lalu Srigede
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.146

Abstract

Background : Laboratory examination for UTI consists of urine culture and dipstick urinalysis consisting of glucose, protein, bilirubin, urobilinogen, erythrocytes, pH, ketones, specific gravity, leukocytes and nitrites. In this study, only protein and urine specific gravity were examined, because one of the causes of proteinuria is post-renal which occurs due to infection in the urinary tract. Meanwhile, for urine specific gravity, patients who are suspected of having a urinary tract infection usually have a high urine specific gravity due to an increase in the number of leukocytes in the urine. UTI can cause a decrease in kidney function due to the risk of infection in the ureters which can cause several complications of kidney disease. Research Objective : To find out whether there is a relationship between the results of urine culture examination and the results of protein and specific gravity of urine as an examination of kidney function in UTI patients. Research Method : This research is an analytical observational research with a cross sectional research design. By examining urine culture and urinalysis using the dipstick method and analyzed using the chi square test. Results of the study : The results of data analysis showed a significant relationship in the positive direction with the strength of the relationship being quite strong between urine culture examination and urine protein results in UTI patients (p 0.030˂0.05). And there is a significant relationship in the positive direction with the strength of the relationship being quite strong between urine culture examination and urine specific gravity results in UTI patients (p 0.021<0.05). Conclusion : There is a significant relationship in the positive direction with the strength of the relationship being quite strong between the results of the protein examination and the urine culture results in UTI patients, as well as the results of the specific gravity examination and the strength of the urine culture results in UTI patients, there is a significant relationship in the positive direction with the strength of the relationship being quite strong.
Immune Response Analysis of Children with Pulmonary TB Using Immuno Chromatography Test -Tuberculosis (ICT - TB) Ariami, Pancawati; Astriani, Astriani; Inayati, Nurul; Khusuma, Ari
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 1 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i1.361

Abstract

Risk factors that increase the spread of Mycobacteria tuberculosis to family members are a history of contact with tuberculosis sufferers and overcrowding at home. If the child has family or close contact with a positive TB sufferer, screening is necessary. Close contact means children live in the same house or often meet the patient. TB testing involves taking sputum samples, but in reality officers often have difficulty taking sputum samples, especially children, so they have to carry out an immunochromatography-tuberculosis (ICT-TB) test. ICT-TB is a serological examination that functions as an alternative screening examination for children who have difficulty collecting sputum. To determine the immune response in children suffering from tuberculosis using the immunochromatography tuberculosis test (ICT-TB). This research is an analytical observational study with a cross-sectional design and uses a saturated sampling method where the entire population is sampled. Purposive sampling was then used to select samples during household visits so that a total sample of 44 samples was obtained.In a sample of 44 children suffering from pulmonary tuberculosis, all ICT-TB test results were negative. 55% of children with suspected pulmonary TB were boys and 45% were boys, the number of children with suspected TB in the 1st, 2nd, 3rd, 4th, 5th and 6th months of treatment was 4.2% and 16.7% respectively. %, 21%, 16.7 %, 33.3%, 8.3% and 18.3%. Based on observations of the children's health status, 43% were healthy and 2% were sick, and in terms of physical factors, the suspect's house had good physical environmental factors. All 44 suspected children had negative ICT-TB test results. Further research needs to be carried out using cohort studies, observing the development of children with tuberculosis over a period of ± 1 to 2 years, and studying contacts in families of non-children aged 0 to 14 years.  
Lipid Profile Animal Trial Model of Metabolic Syndrome with Soggak Coffee Intervention Dewi, Lale Budi Kusuma; Permatasari, Lina; Khusuma, Ari; Agrijanti, Agrijanti
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 1 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i1.712

Abstract

Sindrom metabolik adalah suatu kondisi yang berhubungan dengan obesitas, diabetes, dislipidemia (hiperkolesterolemia dan hipertrigliseridemia), dan tekanan darah tinggi. Stres oksidatif memiliki keterkaitan dengan sindrom metabolik, makanan kaya flavonoid bermanfaat untuk pencegahan dan perbaikan sindrom metabolik. Songgak adalah kopi yang dicampur dengan rempah-rempah dengan kandungan flavonoid dan fenolik total yang berkorelasi dengan aktivitas antioksidannya. Penelitian ini bertujuan untuk menganalisis efek kopi songgak dalam mencegah sindrom metabolik. Parameter yang diuji adalah profil lipid yang terdiri dari kadar kolesterol total, kadar trigliserida, kadar low-density lipoprotein (LDL), dan kadar high-density lipoprotein (HDL). Sebanyak 24 ekor hewan coba dibagi menjadi 4 kelompok (kelompok kontrol, P1, P2, dan P3).  Semua hewan diberikan makanan tinggi, lipid, dan Propylthiouracil (PTU). Kelompok P1, P2, dan P3 masing-masing diberi 8 gram, 12 gram, dan 16 gram kopi Songgak sedangkan kelompok kontrol tidak diberi kopi Songgak. Setelah perlakuan selama 21 hari, hewan coba diterminasi dan profil lipid diukur. Uji statistik dengan Kruskal Wallis pada kadar total kolesterol dan HDL kolesterol dengan hasil uji nilai P berturut-turut adalah 0,205 dan 0,637 (P>0,05), disimpulkan tidak ada perbedaan antar kelompok perlakuan. Sedangkan kadar trigliserida dan LDL diuji dengan uji parametrik ANOVA, hasil uji nilai sig berturut-turut adalah 0,068 dan  0,748 >0,05 disimpulkan tidak ada perbedaan antar kelompok perlakuan. Walaupun menurut uji ststistik disimpulkan tidak ada perbedaan antar kelompok perlakuan, namun kadar kolesterol total, trigliserida, kolesterol LDL dan kolesterol HDL pada kelompok perlakuan lebih baik daripada kelompok kontrol. Kelompok P2 menunjukkan kadar kolesterol total, gliserida, dan LDL yang terendah dengan kadar secara berurutan yaitu 69,67±11,86; 51,00±892; dan 9,33±3,01 mg/dL. Sementara itu, kadar HDL tertinggi pada kelompok P3. Terdapat penurunan kadar kolesterol total, kolesterol LDL, dan trigliserida, serta peningkatan kadar kolesterol HDL pada kelompok perlakuan. Oleh karena itu, kopi songgak dapat dikembangkan menjadi minuman tradisional untuk mencegah sindrom metabolik.
Pengaruh Lama Senam terhadap Kadar Trigliserida pada Kelompok Program Pengelolaan Penyakit Kronis (PROLANIS)  di Puskesmas Dasan Tapen Viefa Avrilian Alifah; Lale Budi Kusuma Dewi; Lalu Srigede; Ari Khusuma
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 2 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i2.32

Abstract

Sindrom metabolik ditandai oleh salah satunya kadar trigliserida tinggi yang meningkatkan risiko penyakit kardiovaskular. Aktivitas fisik seperti senam merupakan upaya non-farmakologis untuk menurunkan trigliserida. Program Pengelolaan Penyakit Kronis (prolanis) yang diselenggarakan oleh BPJS Kesehatan menyediakan kegiatan senam secara rutin sebagai bagian dari upaya pengendalian penyakit kronis. Namun, efektivitas senam prolanis terhadap kadar trigliserida masih belum banyak diteliti, terutama dalam kaitannya dengan lama partisipasi senam. Untuk mengetahui ada pengaruh lama senam terhadap kadar trigliserida pada kelompok program pengelolaan penyakit kronis (prolanis) di Puskesmas Dasan Tapen. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross-sectional. Sampel sebanyak 23 responden yang mengikuti senam setiap 1x setiap minggu dengan variasi lama partisipasi. Pemeriksaan trigliserida menggunakan metode enzimatik GPO-PAP, sedangkan data mengenai lama mengikuti senam diperoleh melalui kuesioner. Analisis data menggunakan uji Shapiro-Wilk, Anova, dan uji lanjutan Tukey HSD. Terdapat penurunan kadar trigliserida berdasarkan variasi lama bulan mengikuti senam. Hasil Anova menunjukkan perbedaan signifikan antar kelompok (p = 0,000 < 0,05). Kadar trigliserida tertinggi ditemukan pada bulan ke-3 yaitu 247,50 mg/dL, sedangkan kadar terendah pada bulan ke-9 yaitu 111,33 mg/dL. Lama mengikuti senam berpengaruh signifikan terhadap penurunan kadar trigliserida. Efek penurunan terlihat nyata setelah 6 bulan partisipasi rutin. Namun, faktor lain seperti pola makan, konsumsi obat-obatan, dan aktivitas fisik tambahan juga turut memengaruhi hasil.
Utilization Of Kuku Pancar (Lawsonia Inermis Lin) Leaves as a Substitute For Eosin Dye in The Examination of Soil Transmitted Helminth (STH) Eggs Yusari, Lala Deswinta; Srigede, Lalu; Manu, Thomas Tandi; Khusuma, Ari
Jurnal Analis Medika Biosains (JAMBS) Vol 11, No 1 (2024): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v11i1.356

Abstract

Nail surfacing leaves (Lawsonia inermis lin) are natural materials commonly used as dyes, because of the content of chemical compounds in them such as lawsone, flavonoids, tannins and anthocyanins, therefore nail surfacing leaves can be used as an alternative dye to replace 2% Eosin in STH worm egg examination, because it has the same properties as 2% Eosin and can produce an orange yellow color after the extraction process. The research objective is to determine the results of nail surfacing leaves (Lawsonia inermis lin) can be used as an alternative substance to replace Eosin in the examination of STH (soil transmitted helminth) worm eggs. The methods of this research is using is experimental, where this study looks at the clarity of soil transmitted helminth (STH) worm eggs on preparations, using coloring from the results of soaking the leaves of the nail surf as a substitute for Eosin. The results of the research is that the coloring results obtained in each variation of immersion time are good. The conclusion of this research is that the staining of worm eggs using the results of immersion of nail surfacing leaves for 12 hours, 24 hours, 36 hours, and 48 hours can be used as an alternative dye in the examination of STH worm eggs.
Analisis Konsentrasi Letal Dan Waktu Letal Isolat Jamur Aspergillus Niger Terhadap Nyamuk Aedes Aegypti Kadek Sinta Cahyani, Ni Diah; Wiadnya, Ida Bagus Rai; Khusuma, Ari; Getas, I Wayan
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.264

Abstract

Latar Belakang: Nyamuk Aedes aegypti merupakan penyebab utama penyakit DBD, kasus DBD di dunia pada tahun 2015 sebanyak 3,2 juta kasus. Di Indonesia pada tahun 2018 terdapat 65.602 kasus. Upaya pengendalian terhadap vektor DBD telah banyak dilakukan baik dengan menggunakan insektisida kimia dan alami salah satunya dengan jamur Aspergillus niger sebagai fungi entomopatogen. Tujuan Penelitian: Mengetahui konsentrasi letal dan waktu letal dari isolat jamur Aspergillus niger terhadap nyamuk Aedes aegypti.  Metode Penelitian: Penelitian ini merupakan penelitian true eksperimental dengan rancangan acak lengkap. Perlakuan dengan 3 konsentrasi isolat jamur Aspergillus niger yaitu 10-5, 10-6, 10-7 spora/ml dengan 6 replikasi. Penelitian ini menggunakan obat nyamuk semprot sebagai kontrol positif. Data diperoleh dianalisa secara statistik menggunakan analisis probit. Hasil Penelitian: Konsentrasi isolat jamur Aspergillus niger yang efektif terhadap nyamuk Aedes aegypti adalah konsentrasi 10-7. Hasil analisis probit uji patogenitas isolat jamur Aspergillus niger terhadap nyamuk Aedes aegypti dengan tingkat kepercayaan 95% didapatkan LC50, LC70, LC90 adalah 6,1 x 107 spora/ml, 8,5 x 107 spora/ml, 1,1 x 108 spora/ml dan diketahui LT50, LT70, LT90 berturut-turut adalah 1,919 jam, 1,510 jam, 1,184 jam. Kesimpulan: Konsentrasi isolat jamur Aspergillus niger secara signifikan memberikan pengaruh terhadap kematian nyamuk Aedes aegypti.
Analisis Jumlah dan Jenis Bakteri Coccus Gram Positif pada Sisa Sampel Darah di Spuit Arfi, Sofiyan Dwi; Kristinawati, Erna; Khusuma, Ari
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.270

Abstract

.Background: One of the problems in the field of health services that can increase the mortality rate is nosocomial infection. Waste containing pathogenic bacteria can serve as a medium for the spread of disease for health facility workers, sufferers and the public. One of the medical devices that have a high risk factor as an intermediary for infection is a syringe. Bacterial contamination of the syringe after use cannot be ignored. Therefore, further research is needed on waste in health facilities to determine infectious diseases caused by residual blood samples in the syringe. Research Objectives: To determine the presence of gram-positive coccus bacteria in the remaining blood sample in the syringe. Methods: This study used a descriptive observational method with a cross sectional approach to time. The sample size in this study was 14 samples with a sampling technique that is total sampling. Results: It was found that Staphylococcus aureus and Staphylococcus cohnii were found each of the 14 samples. Conclusion: There are gram-positive coccus bacteria, namely Staphylococcus cohnii and Staphylococcus aureus. 
Efektivitas Penggunaan Cuka Apel (Apple Cider Vinegar) Terhadap Daya Hambat Pertumbuhan Staphylococcus Aureus Yang Diisolasi Dari Ulkus Diabetes Mellitus Novianty, Alfiah; Agrijanti, Agrijanti; Khusuma, Ari
Jurnal Analis Medika Biosains (JAMBS) Vol 8, No 1 (2021): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v8i1.200

Abstract

Diabetic ulcers are a chronic complication of Diabetes Mellitus in the form of open sores on the surface of the skin. Staphylococcus aureus bacteria is one of the bacteria that causes infection in wounds. Staphylococcus aureus bacteria will flourish in areas that have infections. An increasingly severe infection will cause gangrene. As it is known that Apple vinegar contains chemicals that are as antibacterial. Therefore apple vinegar can be used as a treatment in inhibiting the growth of Staphylococcus aureus bacteria. This study used a quasi-experimental design with 6 treatments, namely Tetracycline Antibiotics as a negative control of growth, sterile aquadest as a positive control of growth and apple vinegar with concentrations of 100%, 50%, 25%, and 12.5%. Then performed a statistical test using Kruskal Wallis with a confidence level of 95% or α = 0.05. Result: Sample Diabetic Foot Ulcer positively contained Staphylococcus aureus. Test the sensitivity that is done by using vinegar apple effective to inhibit the growth of Staphylococcus aureus at concentrations of 50% with a power resistor of 21.75 mm and a concentration of 100% by 24 mm. Conclusion: Apple Cider Vinegar effective to inhibit the growth of Staphylococcus aureus was isolated from Ulcer Foot Diabetic.
Pengaruh Pencucian Darah Domba dengan NaCl 0,85% Terhadap Pertumbuhan Bakteri Neisseria gonorrhoeae Pada Media CAP Agrijanti, Agrijanti; Intan Suryawatie Yomo, Meidiana; Khusuma, Ari; Kusuma Dewi, Lale Budi
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 1 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i1.259

Abstract

Neisseria gonorrhoeae is a fastidious organism. The growth medium for the bacterial culture of Neisseria gonorrhoeae is a Chocolate Agar Plate (CAP) medium enriched with additional nutrients such as sheep blood, vancomisin, nystatin, and isovitaleX. in general, the making of  CAP  is not washed (defibrinated) the sheep blood, in this research, the sheep blood was washed (defibrinated) with NaCl 0.85%. The purpose of the research is to determine the effect of washed sheep blood with NaCl 0.85% on the growth of Neisseria gonorrhoeae in CAP. The method of this research is a pre-experiment conducted in a laboratory to find out a symptom or effect that arises as a result of the treatment of the sample. The treatment in this research is CAP washed of sheep blood and CAP with unwashed sheep blood as a control. The result is the colonies that grew on CAP treatment were better than colonies that grew on CAP control. The conclusion of this research is there is an effect of washed sheep blood with NaCl 0.85% on the growth of Neisseria gonorrhoeae in CAP medium.
Co-Authors Adila Ika Rahmayati Agata, Annisa Agata, Annisa Agrijanti, Agrijanti Ananda, Dewa Ayu Putu Wiweka Anisa Prisilia Prisilia Annisa Agata Annisa Agata Annisa Agata Annisa Agata Annisa Mulia Anasis Annisa Mulia Annasis Annisa Yuniarni Arfi, Sofiyan Dwi Arini Pradita Roselyin Arini Pradita Roselyn Arini Pradita Roselyn Arini Rosa Sinensis Astriani, Astriani Avinni Maula Fardha Baiq Husaevi Agustiningrum Cahayaningrum, Aryani Dewi, Lale Budi Kusuma Dharmajaya Gisu, I Ketut Budi Erlin Yustin Tatontos Erna Kristinawati Ershandi Resnhaleksmana Eustachius Hagni Wardoyo Fakhmi, Shausan Nabila Fihiruddin, Fihiruddin Fitri Anita, Fitri Getas, I Wayan Hanifa Falahul Ilmi I Gede Arya Santika Arya I Wayan Getas Intan Suryawatie Yomo, Meidiana Ismalia Husna Iswari Pauzi Japlani, Vida Lia Jasmine Chairunnisa Kadek Sinta Cahyani, Ni Diah Kristinawati, Erna Kurnia Rizki Laila Nisa, Isra Lalu Sri Gede Lalu Srigede Lalu Srigede, Lalu Mahayani, I Gusti Ayu Putu Sachita Ni Putu Winda Novianty, Alfiah Nurul Inayati Nurul Inayati Pancawati Ariami Pancawati Ariami Pauzi, Iswari Permatasari, Lina Pradita, Arini Putri, Ni Putu Sintyani RAI WIADNYA, IDA BAGUS Reginata, Ni Luh Vira Rohmi Rohmi, Rohmi Roselyn, Arini Pradita Salsabila, Nadira Siti zaetun Siti Zaetun, Siti Sri Hartuti Suhartiningsih Suhartiningsih Sukma, Al Hadawiyah Pertiwi Supriyanti, Ispi Thoha Firdaus Thomas Tandi Manu Urip Urip, Urip Vani Nurcahyanti Viefa Avrilian Alifah Wiodi Nazhofatunnisa Umami Wulandari, Ayu Nurislami Yudha Anggit Jiwantoro Yudha Anggit Jiwantoro Yunan Jiwintarum Yuriska Safitri Yusari, Lala Deswinta Zaena Safitri, Trysia Zainal Fikri