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All Journal HAYATI Journal of Biosciences Jurnal Keperawatan Indonesia Bionatura Jurnal Natur Indonesia Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Alchemy Jurnal Penelitian Kimia JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE INDONESIAN JOURNAL OF PHARMACY Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Kesehatan Medika Saintika Indonesian Journal of Chemistry Indonesian Food Science and TechnologyJournal Jurnal Keperawatan Muhammadiyah JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmasi Higea Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Pharmaceutical Sciences and Research (PSR) Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Dachriyanus
Faculty Of Pharmacy, Andalas University, Kampus Limau Manis, Padang -25163 PO. Box 143, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : INDONESIAN JOURNAL OF PHARMACY

 1 
DEVELOPMENT AND VALIDATION OF A HPLC METHOD FOR DETERMINATION AND QUANTIFICATION OF RUBRAXANTHONE IN STEM BARK EXTRACT OF MANGOSTEEN Meri Susanti; Dwisesaria Irma Lena; Dachriyanus Dachriyanus
Indonesian Journal of Pharmacy Vol 25 No 4, 2014
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (940.042 KB) | DOI: 10.14499/indonesianjpharm25iss4pp237

Abstract

Rubraxanthone is one of antibacterial  and antioxidant compound which is isolated from stem bark of mangosteen (Garcinia mangostana Linn.). The precise method for analysis of plant constituents is normally a reverse-phase high performance liquid chromatographic (RP-HPLC). Development and validation of a RP-HPLC method for chromatographic separation was carried out on a reversed-phase column Shimadzu ®  Shimp-pack VP – ODS (4.6x250mm) using an isocratic mobile phase of  0.4% formic acid - acetonitrile at  a flow rate 1mL min-1, and detection was  with a UV detector. The linearity of  the proposed method was found in the range of 2.5-25μg/mL-1 with regression coefficient 0.999. Intraday precision studies showed the relative standard deviation ≤1.58% and  inter-day ≤3.20%. Accuracy of the method was determined by a recovery study conducted at 3 different levels, and the average recovery was 102.18%. The Limit of Detection Limit of Quantitation (LOQ) and were 0.47 and 1.56μg/mL-1.The contents of rubraxanthon in the crude was 0.23±0.07%w/w.
Characterization antibacterial constituent from Ficus deltoideusJack leaves Suryati .; Hazli Nurdin; Dachriyanus .; Md Nordin Hj Lajis
Indonesian Journal of Pharmacy Vol 21 No 2, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.054 KB) | DOI: 10.14499/indonesianjpharm0iss0pp134-138

Abstract

An antibacterial constituent, has been isolated from Ficus deltoideus Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13 C NMR 1D and 2D and MS), the structure of this compound was identified as Olean-12en-3β-ol, (β-amyrin), C30H50O. This compound showed antibacterial activities against E. coli, B. subtilis and S.  aureus.  The minimum inhibition concentration (MIC) agains  E.  coli,  B. subtilisand  S. aureusare 230, 380 and 460 (µg/mL) respectively.Key words: Antibacterial activity,Ficus deltoideusJack, β-amyrin
Co-Authors ', Darwati ', Supriyatna . Almahdy . Ellyza . Yanwirasti A. Manaf Ali AA Sudharmawan, AA Abd. Rasyid Syamsuri Abdul Rohman Abu Bakar, Nor Kartini Adriani Susanty Agung Tri Sasongko Alimin, Nur Almahdy A Almahdy, . Amella Gusty Amri Bachtiar Andayani, Regina Andryani, Putu Cisya Aprilya Sri Rachmayanti Darwati - Dewi, Citra Kartika Dian Dwiana Maydinar Dian Handayani Dian Sanita Putri Dira Dira Dira Hefni Ditya Kesumaningrum Dwisesaria Irma Lena Eka Roza Wijaya Ekaprasada, M. Taufik Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elidahanum Husni Ellis Mawarni Elyunaida, Elyunaida Erizal Erizal Faleh Setia Budi Fatma Sri Wahyuni Fitra Yeni Gusty, Amella Hadi Ihsan Hadi Nasbey Haiyul Fadhli Harmawati Harmawati Hazli Nurdin Hazli Nurdin Hazli Nurdin Hazli Nurdin Henny Lucida Hj. Lajisc, Nordin Hj. Lajisc, Nordin Husein Hernadi Bahti Husen H Bahti Husen H. Bahti Husen H. Bahti - I Gusti Bagus Wiksuana Ihsan Ikhtiarudin Jufri Al Fajri Kamal Rullah Kesumaningrum, Ditya Krisyanella Krisyanella Leni Merdawati Lusianti, Mittha Lusianti, Mittha M. Taufik Ekaprasada M. Taufik Ekaprasada M. V. Sargent Madyawati Latief Magdazaleni, Magdazaleni Maisa, Esthika Ariany Masrul Md Nordin Hj Lajis Md Nordin Hj Lajis Meri Ardianti Meri Susanti Meri Susanti Miftahul Husna Mira Febrina Muharni Muharni Muharni Muharni Muharni Muharni N. H. Ladjis Nancy Dewi Yuliana Netty Suhatri Nilda Lely Nisa, Tadzkia Nordin Lajis Novi Safitri Noviyandi Sayuti Nurdin, Hazli Nurdin, Hazli Nurdina Putri Pedro Anugrah Aswan Putra, Deddy Prima Putra, Deddy Prima Rahma Yulia Rahmat, Rosita Dewi Rahmat, Rosita Dewi Regina Handayani Handayani, Regina Handayani Rizal Fahmi Rob W.M van Soest Rosfita Rasyid Rustini Rustini Salman - Sanusi Ibrahim Saputri, Veny Wahyu Sartika, Zikra Sartika, Zikra Saufitri, Dian Saufitri, Dian Sekar, Andisyah Putri Shinta Sari Dewi Sinata, Novia Sofia, Sri Esky St. Mursyidah Suhaera Suhaera Suhatri Suhatri Supriyatna - Supriyatna Soetardjo Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Surya Dharma Suryati . Suryati Suryati Suryati Suryati Suryati Suryati Suryati Suryati Suryatir - Syofyan Syofyan Tadzkia Nisa Titen Yasril Veny Wahyu Saputri Vetty Priscilla Wijaya, Eka Roza Yanwirasti Yanwirasti Yanwirasti Yanwirasti Yasman, Yulia Yelly Oktavia Sari Yohannes Alen Yufi Aldi Yufri Aldi Yulia Yasman Yunazar Manjang Yunazar Manjang