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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Jurnal Penelitian Kesehatan Suara Forikes AcTion: Aceh Nutrition Journal Acta Biochimica Indonesiana Majalah Kedokteran Andalas Contagion: Scientific Periodical Journal of Public Health and Coastal Health Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Archives Pharmacia Jurnal Ilmu Kesehatan Indonesia (JIKSI) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal of Pharmaceutical and Sciences. Jurnal Riset Ilmiah Proceeding International Health Conference
Endrinaldi
Universitas Andalas
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Hubungan Penderita Asma Perokok Pasif dengan Eksaserbasi Asma di RSUD M. Natsir Solok Alvin Muhammad; Oea Khairsyaf; Endrinaldi Endrinaldi
Jurnal Ilmu Kesehatan Indonesia Vol 3 No 1 (2022): Maret 2022
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v3i1.522

Abstract

Latar Belakang: Asma merupakan penyakit kronis saluran napas yang dipicu oleh berbagai faktor, dan salah satunya adalah paparan asap rokok. Paparan asap rokok dapat meningkatkan risiko eksaserbasi asma dan juga dapat menyebabkan eksaserbasi asma. Objektif: Penelitian ini bertujuan untuk mengetahui hubungan anntara penderita asma perokok pasif dengan derajat eksaserbasi asma di RSUD M. Natsir Solok. Metode: Jenis penelitian ini adalah analitik observasional dengan desain studi potong lintang. Data dikumpulkan dengan metode wawancara menggunakan kuisioner kepada subjek asma. Data yang dikumpulkan berupa usia, jenis kelamin, pekerjaan, riwayat paparan asap rokok, dan derajat eksaserbasi asma. Sampel pada penelitian ini adalah 53 pasien asma perokok pasif yang memenuhi kriteria penelitian. Hasil: Sebanyak 15 (60%) orang yang terpapar asap rokok < 3 jam/hari mengalami eksaserbasi derajat sedang-berat, sedangkan orang yang terpapar asap rokok > 3 jam / hari yang mengalami eksaserbasi derajat sedang-berat berjumlah 26 orang (92,9%). Hasil uji statistik diperoleh nilai p = 0,012 dan nilai OR = 8,667. Kesimpulan: Terdapat hubungan antara penderita asma perokok pasif dengan derajat eksaserbasi asma.
Korelasi antara kadar gula darah puasa dengan stress oksidatif dan aktivitas katalase pada tikus model diabetes melitus tipe 1 yang diterapi dengan MSC-WJ Endrinaldi Endrinaldi
Majalah Kedokteran Andalas Vol 46, No 1 (2023): Online Januari 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i1.p137-144.2023

Abstract

Objective: This study was conducted to investigate the involvement of oxidative damage in type 1 diabetes mellitus rats treated with Mesenchymal Stem Cell Wharton's Jelly (MSC-WJ) and to explain the correlation between fasting blood sugar levels and MDA levels as an indicator of oxidative stress and catalase activity.Methods: This research is experimental research with a Posttest-Only Control Group Design. It consisted of 3 groups, namely group 1 was healthy rats, group 2 was DM rats and group 3 was DM rats treated with MSC-WJ. This study conducted in vivo experiments on alloxan-induced diabetic rat models by testing fasting blood glucose (FBG), serum MDA levels, and catalase activity. Malondialdehyde (MDA) was measured by the Ohkawa method, and catalase activity (CAT) was measured by a modified Sinha method.Results: The results showed the correlation analysis between fasting blood sugar levels and MDA levels (r = 0.697) and catalase activity (r = -0.850) in type 1 DM rats after being treated with Mesenchymal Stem Cell Wharton's Jelly.Conclusion: This study shows a strong positive correlation between fasting blood sugar levels and oxidative stress and a very strong correlation between fasting blood sugar levels and catalase activity of type 1 DM rats treated with MSC-WJ.
Analysis of the Characteristics of Stunting Toddler Mothers in the Working Area of the Anak Air Health Center in Padang City Yaumil Fauziah; Joserizal Serudji; Mayetti Mayetti; Nur Indrawaty Lipoeto; Asrawati Nurdin; Endrinaldi Endrinaldi
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 5, No 1 (2023): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v5i1.14971

Abstract

The incidence of stunting under five is still a major nutritional problem in Indonesia today. Stunting is a chronic nutritional problem caused by many factors such as age, mother's education and occupation, number of children and birth spacing. The purpose of this study was to analyze the characteristics of mothers who have stunted toddlers in the working area of the Anak Air Health Center in Padang City, West Sumatra Province. This research was conducted in the working area of the Anak Air Health Center in Padang City, West Sumatra Province. The time of the research started from November 2022 to January 2023. This research was an observational study with a descriptive approach. The population for this study was all mothers who had stunting toddlers in the Working Area of the Water Children's Health Center in 2022 as many as 337 people. The research sample was 54 stunting toddlers using a simple random sampling technique. Data collection was carried out using a questionnaire. Data analysis used is descriptive analysis. The results of the study are the characteristics of mothers who have stunted toddlers aged 21-35 years as many as 33 (61.1%), mother's work as housewives as many as 52 (96.3%), high school education as many as 37 (68.5%), the number of children >2 was 31 (57.4%), and the birth spacing was ≥3 years and the first child was 37 (68.5%). It is expected that optimal cross-sectoral cooperation in reducing the prevalence of stunting is according to the government's target, which starts from the first level health service center, namely the community health service center and it is suggested to health workers to provide health education to stunting toddlers about the importance of nutritional needs for toddlers in the process of growth and development. toddler development. Keyword: Characteristics, Education, Number and Spacing of Births, Occupation, Stunting Toddlers 
Efek Suplementasi Probiotik Oral Sebagai Terapi Tambahan pada Pasien Dermatitis Atopik Nailatul Fadhila; Gardenia Akhyar; Fory Fortuna; Ennesta Asri; Endrinaldi Endrinaldi; Yusticia Katar
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 2 (2023): Juni 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i2.849

Abstract

Latar Belakang: Dermatitis atopik merupakan peradangan kulit yang menjadi beban penyakit non-fatal dalam dermatologi. Etiologinya belum diketahui secara pasti. Probiotik merupakan bakteri baik yang memiliki potensial untuk menjadi terapi tambahan dermatitis atopik. Objektif: Kajian literatur sistematis ini dilakukan untuk mengetahui efek dari suplementasi probiotik oral sebagai terapi tambahan pada pasien dermatitis atopik. Metode: Studi literatur ini merupakan kajian literature sistematis. Pencarian literatur dilakukan di tiga pangkalan data, yaitu Pubmed, Proquest, dan The Cochrane Central Register of Controlled Trials (CENTRAL). Hasil: Terdapat sebelas studi yang dimasukkan dalam kajian literature sistematis ini dengan 918 kasus dermatitis atopik. Kesimpulan: Probiotik memberikan efek terapi berupa penurunan indeks SCORAD dan meningkatkan kualitas hidup pasien. serta dapat dijadikan sebagai opsi terapi tambahan pada pasien dermatitis atopik
Hubungan Tingkat Stres dan Sleep Hygiene dengan Kualitas Tidur pada Mahasiswa Kedokteran Raisa Hussein; Eldi Sauma; Endrinaldi Endrinaldi; Afriwardi Afriwardi; Havriza Vitresia
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 3 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i3.1045

Abstract

Latar Belakang: Mahasiswa kedokteran merupakan kelompok yang rentan terhadap kualitas tidur yang buruk dan dianggap memiliki tingkat stres yang tinggi dibandingkan dengan mahasiswa jurusan lain. Untuk meningkatkan kuantitas dan kualitas tidur seseorang maka perlu penerapan praktik sleep hygiene secara rutin dalam kehidupan sehari-hari. Sleep hygiene merupakan serangkaian perilaku dan lingkungan untuk menciptakan kualitas tidur yang optimal. Objektif: Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara tingkat stres dan sleep hygiene dengan kualitas tidur pada mahasiswa program studi pendidikan dokter Fakultas Kedokteran Universitas Andalas angkatan 2019-2021. Metode: Penelitian ini merupakan penelitian analitik dengan menggunakan metode cross sectional, menggunakan teknik proportionate stratified random sampling dengan jumlah sampel sebanyak 160 responden. Data responden didapatkan dari kuesioner dan dianalisis menggunakan uji chi square. Hasil: Hasil penelitian ini didapatkan responden perempuan lebih banyak dibandingkan dengan responden laki-laki, dengan usia terbanyak adalah 21 tahun (32,5%). Lebih dari setengah mahasiswa memiliki tingkat stres normal (61,9%) dan sleep hygiene kategori tidak baik (63,8%). Mayoritas mahasiswa memiliki kualitas tidur yang buruk (90,6%). Kesimpulan: Tidak terdapat hubungan antara tingkat stres dengan kualitas tidur (p = 0,215) dan tidak terdapat hubungan antara sleep hygiene dengan kualitas tidur (p = 1,000). Kata kunci: Tingkat stres, sleep hygiene, Kualitas Tidur
Differences in the Effect of Giving Fe Tablets and Capsules Moringa Leaves on Hepcidin and Ferritin Levels in Anemic Pregnancy Rats Novita Sari; Delmi Sulastri; Endrinaldi Endrinaldi
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 5, No 3 (2023): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v5i3.17395

Abstract

Anemia is a condition characterized by a decrease in Hemoglobin (HB), a serious global public health problem especially affecting children and pregnant women. This study aimed to determine differences in the effect of giving Fe tablets and capsules of Moringa leaves on hepcidin and ferritin levels in anaemic pregnancy rats. This research was an experimental study with a randomized post-test-only control group design. This research was conducted at the Animal House of the Faculty of Medicine, Andalas University to maintain and treat experimental animals. Ferritin and Hepcidin examinations were carried out at the biomedical laboratory of the Faculty of Medicine, Andalas University. The sample in this study were female white rats (Rattus Novergicus) which met the inclusion and exclusion criteria, the data were analyzed using One Way Anova. The results of this study indicated that the mean hepcidin levels in the Fe (P1) and Moringa leaf capsule (P2) groups were 181.902 ± 20.31 and 216.362 ± 29.90 with a p-value of 0.006 . The mean ferritin levels in the Fe(P1) and Moringa leaf capsule (P2) groups were 1.928 ± 0.263 and 2.308 ± 0.320 with a p-value of 0.004. The conclusion in this study was that there was an effect on hepcidin levels after being given Fe tablets (P1) and Moringa leaf capsules (P2) to anemic pregnant rats and there was an effect on ferritin levels after being given Fe tablets (P1) and Moringa leaf capsules (P2) to anemic pregnant rats Keyword: Anemic, Ferritin, Fe Tablets, Hepcidin, Moringa Leaf Capsules
Efek Pemberian Mesenchymal Stem Cell Wharton's Jelly (MSC-WJ) terhadap Gambaran Histologi Pankreas Hewan Model Diabetes Melitus Tipe 1 Endrinaldi Endrinaldi; Tofrizal Tofrizal; Elmatris Elmatris; Sisca Dwi Yarni
Majalah Kedokteran Andalas Vol 46, No 10 (2024): Online May 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i10.p1704-1711.2024

Abstract

Objective: This study was conducted to determine the effect of administering Mesenchymal Stem Cell Wharton Jelly (MSC-WJ) on the histological appearance of the pancreas of rat in a type 1 diabetes mellitus model. Methods: This research is an experimental research with a Posttest-Only Control Group Design. The sample consisted of 3 groups (Normal, T1DM, T1DM + MSC-WJ). The treatment group was treated with MSC-WJ for 4 weeks. Data analysis used One Way ANOVA and Post Hoc Bonferroni tests. Results: WJ-MSC can increase the mean diameter and area of the islets of Langerhans in the T1DM rat group from 98.08 mm – 126.85 mm and from 4911.95 mm2 – 8995.35 mm2, but this difference is not yet significant (p > 0.05). Conclusion This research shows that there is improvement in pancreatic damage by administering WJ-MSC to diabetic rat due to alloxan induction.
Jamblang (Syzygium cumini) leaf extract decreased hydrogen peroxide in lead acetate-induced rats Rauza Sukma Rita; Elmatris Sy; Endrinaldi
Acta Biochimica Indonesiana Vol. 5 No. 2 (2022): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.118

Abstract

Background: Free radicals are atoms or molecules with one or more unpaired electrons. Lead acetate has been reported to increase the presence of free radicals in the body. Objective: This study aims to investigate the effect of oral administration of jamblang (Syzygium cumini) leaf extract on hydrogen peroxide (H2O2) serum levels in rats induced with lead acetate. Methods: A total of 24 male rats were divided into three groups: the negative control, the positive control, and the treatment group. The negative control group received a standard diet, the positive control group received lead acetate at a dose of 40 mg/kg body weight, and the treatment group received lead acetate at the same dose along with jamblang leaf extract at a dose of 150 mg/kg body weight. Lead acetate and jamblang leaf extract administration was carried out for 30 days. Afterward, serum H2O2 levels were examined using the colorimetry method. Results: Results revealed that H2O2 levels in the negative control, positive control, and treatment groups were 3.08±0.24, 4.94±0.75, and 3.44±0.65 nmol/L, respectively. Significant differences were observed between the groups, as well as between the negative control and positive control, and between the positive control and treatment group. Conclusion: The study showed that jamblang leaf extract can reduce hydrogen peroxide levels in Wistar rats treated with lead acetate, indicating its ability to address oxidative stress.
Characteristics of Gastroesophageal Reflux Disease (GERD) Patients at RSUP Dr. M. Djamil Padang Period 2018-2021 Setiawan, Mentari Adinda; Fasrini, Ulya Uti; Amir, Arni; Muchtar, Masrul; Miro, Saptino; Endrinaldi, Endrinaldi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 3 (2023): VOLUME 24, NUMBER 3, December, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2432023227

Abstract

Background: Gastroesophageal reflux disease (GERD), a common digestive problem, is increasing and affecting the individual’s quality of life. This study aimed to describe the characteristics of GERD patients at Dr. M. Djamil Central General Hospital.Method: This cross-sectional study used data from patients' medical records that involved 111 GERD patients, excluding chronic disease and pregnancy. The analysis used univariate analysis and performed the data in cross-tables.Results: The results indicated that demographically, nearly all of the samples fall within the range of productive age (94.59%), with a higher proportion of the female gender (54.05%), the majority having a middle education level (72.08%), being housewives (27.92%), and residing in Padang City (35.13%). Most of the main symptoms were heartburn (62.16%), followed by vomiting, nausea, and dysphagia (4.50%, 2.70%, and 1.80%). More patients received outpatient treatment with two visits (18.02%). Clinically, based on the BMI, the obese classification was higher (43.25%). The levels of triglycerides and total cholesterol in the blood of GERD patients were more in the normal category (60.60% and 61.80%), while the levels of HDL and LDL in the blood of GERD patients were in the abnormal category, with lower HDL (97.80%), and a higher LDL (72.70%).Conclusion: The majority of GERD patients were in the productive age group, female, middle level of education, housewives, and resided in Padang. Clinical characteristics of GERD patients included most were categorized as obese according to their BMI, main symptom heartburn, and treated as an outpatient. Triglyceride and total cholesterol were primarily normal; blood HDL and LDL were abnormal.
Edukasi Tentang Anemia dan Pemeriksaan Hb pada Ibu Hamil serta Pengobatan pada Masyarakat di Nagari Carocok Anau Kec.Tarusan Kab. Pesisir Selatan Elmatris Sy; Dessy Arisanti; Almurdi Almurdi; Endrinaldi Endrinaldi; Bobby Indra Utama; Dian Pertiwi; Rauza Sukma Rita; Zelly Dia Rofinda; Hasmiwati Hasmiwati; Aswiyanti Asri; Julizar Nazar; Mohamad Reza
Warta Pengabdian Andalas Vol 31 No 3 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.3.591-598.2024

Abstract

The majority of people of Nagari Carocok Anau Kec. Tarusan Kab. Pesisir Selatan worked as a fisherman, farmer, a small number of civil servants and market traders, as well as a housewife. Pregnant women in Nagari Carocok Anau, most of whom are housewives, still do not receive health checks such as haemoglobin (Hb) checks. This activity aims to increase knowledge among the public and health cadres regarding anaemia and Hb examination in pregnant women, as well as treatment. The health of pregnant women is checked by checking blood pressure, Hb and medication. This Hb examination is an effort to minimize abnormalities that can occur in pregnant women and fetuses due to low Hb when the mother is pregnant. The examination results showed that more than half of the pregnant women (71.43%) who attended were in the age range 18 – 35 years. Nearly half (42.86%) of pregnant women had Hb levels below the normal limit (11 mg/dl). For a more valid diagnosis, it is necessary to carry out quantitative analysis from the hospital laboratory so that follow-up can be carried out. Education about anaemia and Hb examinations in pregnant women can increase people's knowledge so that preventive measures can be carried out early. Health checks on the general public (blood pressure, Hb) and treatment were also carried out, it was found that the Hb results were within normal limits.
Co-Authors Adrial Adrial Afriani, Nita Afriwardi Afriwardi Almurdi Almurdi Alvin Muhammad Arni Amir Asrawati Nurdin Asterina Asterina Aswiyanti Asri Aswiyanti Asri Bobby Indra Utama Delmi Sulastri Desmiwati Desmiwati2 Dessy Arisanti Dessy Arisanty Dia Rofinda, Zelly Dia Dian Pertiwi Dira Hefni Dira, Atshyfa Zsazsa Djosan, Al Hafiz Dwi Yulia Effy Huriyati Efrida Efrida Eldi Sauma Elmatris Sy Ennesta Asri Erlina Rustam Erly Erly Ervan Arditya Kusuma Fadil Oenzil Fathoni Afif Feby Febriatama Fitria Ramanda Fortuna, Fory Gardenia Akhyar Gian Primahana Gita Rahmadani Gusti Revilla Hasmiwati Husna Yetti Husnil Kadri Ibrahim Ibrahim Ilham, Nur Muhammad Intan, Shinta Ayu Irrahmah, Miftah Jepri Agung Priyanto Julizar Nazar Linosefa Linosefa Lisma Evareny Magza, Dekasih Tria Mahata, Liganda Endo Masrul Mayetti Mayetti Miftah Irramah Mohamad Reza Muchtar, Masrul Muhammad Eka Prastya Nadhira Isza Qushoyyi Nadia Oktarina Nailatul Fadhila Novita Sari Nur Afrainin Syah Nur Indrawaty Lipoeto Nurhayati Nurhayati Nurul Fadila Oea Khairsyaf P, Anastasya Inayah Nabila Putri, Biomechy Oktomalio Rafifa Ridha Rahmani Welan Raisa Hussein Ramadhani, Dhea Amaliya Rani Afrisetiawati Rauza Sukma Rita Rikarni Rikarni Rizki Amelia Roslaili Rasyid Saptino Miro Saptino Miro, Saptino Sari Handayani Utami Setiawan, Mentari Adinda Sisca Dwi Yarni Siti Utari Agustina Sri Wahyuni Suci Aulia Yude Tofrizal Triyunita, Rian Ulya Uti Fasrini Vitresia, Havriza Yarni, Sisca Dwi Yaumil Fauziah Yerizel , Eti Yuniar Lestari Yusticia Katar Yustini Alioes Zelly Dia Rofinda Zetryana Puteri Tachrim Zulkarnain Edward