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Perbandingan Efektifitas Metilprednisolon Intravena dengan Oral pada Kasus Grave Ophthalmopathy di RSUP Dr M Djamil Padang Efendi, Mardijas; Hendriati, Hendriati; Primasakti, Pattih; Erwen, Yolanda Wulandari
Jurnal Kesehatan Andalas Vol. 14 No. 1 (2025): March 2025
Publisher : Faculty of Medicine, Universitas Andalas

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Abstract

Grave's Ophthalmopathy can occur in three phases depending on the inflammatory process.  Immunosuppressant therapy is an anti-inflammatory option for managing the active phase of GO.  A study showed a significant improvement in GO proptosis in patients treated with methylprednisolone.  Objective: To determined the frequency of proptosis in Thyroid Eye Disease  (TED) patients and the differential effect of oral or intravenous steroid administration.  Methods: This study was a prospective cohort study through medical record data from March 2023 to March 2024.  The subjects are all inpatients with thyroid eye disease in Dr M Djamil General Hospital, Padang.  T-tests were performed to determine each group's different perceptions.  Results: Thirty-six subjects with Grave’s ophthalmopathy.  The effect size of the changes in Hertel values in patients given both oral and intravenous corticosteroid therapy is significant in both eyes.  The effect size of the oral therapy is significant, with 0.341 in the right eyes and 0.303 in the left eyes.  The intravenous therapy is also significant, with the effect size 0.347 in the right and 0.271 in the left.  The change of Hertel value in patients given both oral and intravenous corticosteroid therapy is significant in the right eyes (p = 0.009 and p = 0.008).  Conclusion: Oral and injectable corticosteroids have similar effectiveness, thus providing flexibility in therapy selection for patients with thyroid eye disease. Keywords:  Grave ophthalmopathy, intravenous methylprednisolone, oral methylprednisolone
Screening Cataract and Other Visual Impairment by PELITA Cadre to Build Vision Center in Lima Puluh Kota Regency Ariesti, Andrini; Hendriati, Hendriati; Hidayat, Muhammad; Irayanti, Irayanti; Ilahi, Fitratul; Yuswir, Astria Rima Rara; Lonanda, Gama Agusto; Primasakti, Pattih; Roza, Silvia; Syafendra, Atika; Afelita, Tia; Putra, Heru Ardila; Suhery, Suhery; Irza, Metika Rahmasari; Lucyana, Lucyana; Maralaut, Azhardin; Zulferza, Jaka
Warta Pengabdian Andalas Vol 32 No 3 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.3.390-399.2025

Abstract

Eye diseases, particularly cataracts, are the leading cause of blindness worldwide. This community service program by the Department of Ophthalmology, Faculty of Medicine, Andalas University, was conducted at the Pangkalan Public Health Center, Lima Puluh Kota Regency, by empowering PELITA (Posyandu) cadres in early detection of cataracts. Methods included counseling, training, and eye examination simulations for 40 cadres, followed by community screening using visual acuity and anterior segment examinations. Evaluation was carried out with pre- and post-tests, satisfaction surveys, and follow-up on patients referred for surgery. The average cadre score improved from 68 (pre-test) to 74.5 (post-test), indicating increased knowledge. A total of 71 patients were screened, including 40 cataract and 8 pterygium cases; 26 cataract and 4 pterygium patients subsequently underwent surgery. Cadres reported high satisfaction with the training and expressed readiness to continue participation. This program demonstrates that cadre training is effective in improving early detection of cataracts and other visual impairments, and provides a foundation for establishing a Vision Center in Lima Puluh Kota.
Co-Authors Adila Hanna Adrial Adrial Afelita, Tia Afriwardi Afriwardi Agustin Vira Agustin Vira Aisyah Elliyanti Al Hafiz Alhakim, Hafidh Taufiq Alifia Damanil Putri Almurdi Almurdi Andrini Ariesti Andrini Ariesti Andrini Ariesti Andrini Ariesti Anum, Qaira Ariesti Andrini Ariesti, Andrini Arina Widya Murni Astria Rima Rara Yuswir Astria Rima Rara Yuswir Aulia Deddy Saputra Deny Wiryulisda Desty Ria Tiffani Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Dolly Irfandy Dwitya Elvira, Dwitya Efendi, Mardijas Elmatris Sy Elmatris, Elmatris Ennesta Asri Ennesta Asri Erlina Rustam Erwen, Yolanda Wulandari Febiyola Ratu Khairani Fortuna, Fory Frizki Amalya Putri Gama Agusto lonanda Gardenia Akhyar Guntur Fazwat Gustia Anugrahwati Hanum, Fathiya Juwita Hasmiwati Helvinda Weni Heru Ardila Putra Husnil Kadri Husnil Wardiyah Ilahi, Fitratul Ilmiawati, Ilmiawati Indah Indria Sari Indah Indria Sari Indah Syafira Praja Irayanti Irayanti, Irayanti Irza, Metika Rahmasari Izzati Mujahidah Julita Julita Julita Julita Julita Julizar Julizar Julizar Julizar Kelvin Mandela Kemala Sayuti Khairiah Nevrianty Laila Isrona lonanda, Gama Agusto Lucyana Lucyana, Lucyana Maralaut, Azhardin Mardijas Efendi Moestafa Nur Muhammad Fadhil Rahmadiansyah Muhammad Hidayat Muhammad Hidayat Muhammad Syauqie Nasyayya Akbari Nazar Nesa Pratiwi Noverika Windasari Novian Novian Novian Novian Pratama Yogi Primasakti, Pattih Rahim, Beby Rahmadiansyah, Muhammad Fadhil Rahman, Ardizal Rahman, Ardizal Rahmat Syawqi Rahmat Syawqi Rendra Darma Satria Rendra Darma Satria Rika Desviorita Rika Desviorita Rimelda Aquinas Rina Gustia Rina Gustia Rino Agustian Praja Rizanda Machmud Rizki Dwayana Rizki Dwayana Roza, Silvia Rudy Afriant Rustam, Raihana Satya Wydya Yenny Sherly Muchlis Silvia, Nelmi Siti Syiehan Muhdalin Suhery, Suhery Syafendra, Atika Tofrizal Tofrizal Trisno, Assyifa Azzahra Dwi Tutty Ariani Tutty Ariani Ulya Uti Fasrini Vitresia, Havriza Wati Rinda Weni Helvinda Weni Helvinda Yulistini, Yulistini Zacky Aulia Mursi Zulferza, Jaka