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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

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AKTIVITAS ANTIBAKTERI DAN KOMPONEN KIMIA MINYAK ATSIRI TEMU KUNCI (Boesenbergia rotunda L. Mansf) TERHADAP BAKTERI PENYEBAB JERAWAT Mulyaningsih, Sri; Anastasya, Yolanda; Darmawan, Endang
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.1924

Abstract

Essential oil of fingerroot (Boesenbergia rotunda L. (Mansf)) have antibacterial activity against Staphylococcus but was not specific against acne-causing bacteria. The aim of this study was to determine its chemical content and antibacterial activity of the fingerroot oil against S. aureus, S. epidermidis, and Propionibacterium acnes that cause acne. The essential oil was isolated by steam and water distillation. The organoleptic, yield, and refractive index were observed. Gas chromatography-mass spectrometry (GC-MS) carried out the identification of essential oil components. Antibacterial activity of the oil was determined with the diffusion method. Broth microdilution methods was used for determination of the minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC). Fingerroot essential oil was clear in color, aromatic odor, chelate taste, and slightly bitter with a yield of 1.19%. The refractive index was 1.4785 ± 0.0001. GC-MS identification showed 5 main components of fingerroot oil were camphor (28.70%), ocimene (24.71%), eucalyptol (16.26%), geraniol (14.81%), and methyl cinnamate (4.16%). The diameter of the zone of inhibition of bacterial growth was greatest at 20% concentration of fingerroot oil, followed by 10%, 5%, and 2.5%. MIC value of fingerroot oil against S. aureus and S. epidermidis was 0.625% and against P. acnes was 1.25%. The MBC value of fingerroot oil was doubled as the MIC value. The great antibacterial activity of fingerroot essential oil makes it potential to be developed into anti-acne preparations.
Co-Authors -, Nova Anggreni . Djumali A. Hiola, Fidyawati Aprianti Ahmad, Ardha Nurul Ahmad, Zul Fikar Alamri, Luthfia Ali, Rizky Nikmathul Husna Anastasya, Yolanda Andhika Djalu Sembada Anggreni, Nova Annajmi, Annajmi Apriliani, Leni Arcat, Arcat Arief, Syachrul Arif Budi Setianto Arif Wardana, Muhammad Baba, Abdul Faisal Budi Hariyono Budi Priyono Busro, Djumali dabutar, afif handika De Budi Irwan Taofik Devi, L R Devi, L R Dina Tania DJUMALI DJUMALI, DJUMALI Dwi Indah Purnamawati, Dwi Indah Edhy Sutanta (Jurusan Teknik Informatika IST AKPRIND Yogyakarta) Emilliana Natalia Trisakti Susanti, Maria Endang Darmawan Ery Fatarina Purwaningtyas Euis Erlin Fathoni, Shalsabila Destyari Fatmah Zakaria, Fatmah Firsty, Girly Risma Gani, Samsul Abdul Habibi, Nurul Is'ad Hasan, Nuradnin Hasanah, Setia Nur Heri Prabowo Heriyadi, Nur Widi Astanto Agus Tri Hidayah, Radhitya Adzan Hidayati, Fika Hiola, Fidyawati Aprianti A. Husadani, Y T Husadani, Y T Husna Ali, Rizky Nikmathul Husni Mubarak Ichwan Ridwan Rais IGAA. INDRAYANI, IGAA. Iis Wahyuningsih Imam Riadi Indrawati Wilujeng Irawan, S N Irawan, S N Ishak, Fifi Jussac Maulana Masjhoer Karwanto, Karwanto Katili, Dwi Nur Octaviani Katili, Tressan Eka putri Laila, Wahyu Kumil Leni Sri Mulyani Lestari, Taufika Putri Levana Sondakh Lusi Eka Afri Ma'la, Sidqi Yajidil Maghfirah, Rahmayani Manjurungi, Gia Arista Putri Maulani, Rakhil Meylina, Meylina Moch. Saiful Bachri Mufarrihul Hazin MUHAMMAD SHOLEH Muhammad Suyanto, Muhammad Mulyani, Eva Nining Sugihartini Nur Handayani Nur Mahdi Nur Rahmawati Nuraeni, Sinta Nurdin, St Surya Indah Nurdin, St.Surya Indah Nurrahmawati Nurul Hasanah Pertiwi, Citra Prakoso, Aditha Agung Priyanto, Sabda Elisa Rahayu, Hanifah Aulia Rahmandhala, Ilvan Dino Ranila, Suciati Rauf, Efri Leny Ria Indah Pratami Samuel Kristiyana Sanjoto, Siwi Santi Anggraeni Sapto Yuliani Septina, Norma Dewi Sidiq, Purnomo Siti Fatmawati Fatimah, Siti Fatmawati Suhartono Supratno, Haris Supriyadi, Asep Adang Susila, Aceng Ahmad Rodian Teger Basuki Umar, Siskawati Umboro, P A Vienastra, Septian Widayati, Wiludjeng Wiloso, Danis Agoes Wirono, Maryani Eka Wiwik Handayani Yosef Prihanto, Yosef Yuliandary Yunus Yunengsih, Yuyun