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All Journal International Journal of Advances in Applied Sciences Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Hemera Zoa Vegetalika VALENSI Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences JURNAL KIMIA SAINS DAN APLIKASI Current Biochemistry AGRIVITA, Journal of Agricultural Science agriTECH Indonesian Journal of Chemistry Agrin : Jurnal Penelitian Pertanian Justek : Jurnal Sains Dan Teknologi Biosaintifika: Journal of Biology & Biology Education Media Farmasi Journal of Tropical Crop Science AGROSAINSTEK: Jurnal Ilmu dan Teknologi Pertanian Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia YARSI Medical Journal Poltekita : Jurnal Ilmu Kesehatan Jurnal Farmamedika (Pharmamedica Journal) Indonesian Journal of Contemporary Multidisciplinary Research Indonesian Journal of Jamu
Waras Nurcholis
Departemen Biokimia, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor (IPB University), Jl. Agatis, Kampus IPB Darmaga, Bogor 16680, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Media Farmasi

 1 
PROFIL KROMATOGRAFI LAPIS TIPIS EKSTRAK KUNYIT (Curcuma longa Linn) SEGAR DAN SIMPLISIA DENGAN VARIASI METODE EKSTRAKSI Sadwika Najmi Kautsari; Edy Djauhari Purwakusumah; Waras Nurcholis
Media Farmasi XXX Vol 16, No 1 (2020): Media Farmasi
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar, Kementerian Kesehatan RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.576 KB) | DOI: 10.32382/mf.v16i1.1403

Abstract

Turmeric is a rhizome plant used as traditional Indonesian medicine. Generally, the extraction process influences the efficacy of turmeric in curing a disease. This study compares the thin layer chromatography profile (TLC) of turmeric extract based on variations in the extraction method. The extraction process was carried out using 70% ethanol solvent in fresh rhizomes and turmeric simplicia. The study used maceration, sonication, and microwave assistance techniques. The thin layer chromatography profiles were analyzed using curcuminoid standards in visible and UV light visualization (254 and 366 nm). The results showed higher yields in the fresh turmeric extracts through maceration extraction, sonication, and microwave-assisted techniques, respectively. The thin layer chromatography pattern using eluent chloroform dichloromethane (32.5: 67.5 v / v) showed the extract was separated into 3 - 4 compounds, with different curcuminoid thicknesses in each treatment. The thin layer chromatography profile with the highest quality of curcuminoid content was found successively in sonication simplicia,  maceration, and microwave simplicia extracts, as well as sonication fresh turmeric extract, maceration, and microwaves. The high yield of turmeric extract does not indicate an increase in the quality of the curcuminoid levels produced.Keywords: Turmeric, Thin Layer Chromatography, curcuminoids, extraction modificationKunyit merupakan tanaman rhizoma yang telah dimanfaatkan dalam pengobatan tradisional Indonesia. Khasiat kunyit dalam menyembuhkan suatu penyakit dipengaruhi oleh proses ekstraksinya. Penelitian ini bertujuan membandingkan profil kromatografi lapis tipis (KLT) ekstrak kunyit berdasarkan variasi metode ekstraksi. Proses ekstraksi dilakukan menggunakan pelarut etanol 70% pada rimpang segar dan simplisia kunyit. Teknik ekstraksi yang dilakukan adalah secara maserasi, sonikasi dan bantuan gelombang mikro. Profil kromatografi lapis tipis dianalisis dengan menggunakan standar kurkuminoid pada visualisasi sinar tampak serta UV  (254 dan 366 nm). Hasil penelitian menunjukkan rendemen yang lebih tinggi terdapat pada jenis ekstrak kunyit segar daripada simplisianya, secara berturut-turut melalui teknik ekstraksi maserasi, sonikasi, dan bantuan gelombang mikro. Pola kromatografi lapis tipis ekstrak dengan menggunakan eluen kloroform:diklorometan (32,5:67,5 v/v) menunjukkan bahwa ekstrak terpisah menjadi 3 - 4 senyawa, dengan  ketebalan kurkuminoid yang berbeda pada masing-masing perlakuan ekstraksi. Profil kromatografi lapis tipis dengan kualitas kadar kurkuminoid tertinggi terdapat pada ekstrak simplisia secara sonikasi, disusul dengan ekstrak simplisia secara maserasi dan gelombang mikro, serta ekstrak kunyit segar secara sonikasi, maserasi, dan gelombang mikro. Rendemen yang tinggi dari ekstrak kunyit tidak mengindikasikan kualitas kadar kurkuminoid yang dihasilkan semakin baik.Kata kunci: Kunyit, Kromatografi Lapis Tipis, kurkuminoid, modifikasi ekstraksi
Co-Authors A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Alfari Andiqa Muhammad Ali Umar Amalia Prihaningsih Anggriawan, Made B. Ani Kurniawati Annisa Dhiya Athiyyah Khanza Antonius Padua Ratu Antonius Padua Ratu Anyalirria Apipah Aprianti Arianti, Rini Arifin, Poppy F. Arya Arendra Baharuddin Yusuf Habibie Bambang Pontjo Priosoeryanto Bintang, dan Maria Binukajati, Farras Agung Chelsea Chelsea, Chelsea Damarhati, Lelly Aulia Dewi Sukma Dian Apriliani, Dian Dian R. Laksmitawati DIMAS ANDRIANTO Djarot Sasongko Hami Seno Dolfina Costansah Koirewoa Dyah Sulistyani Rahayu Edoward Krisson Raunsay Edy Djauhari Purwakusumah Edy Djauhari Purwakusumah Edy Djauhari Purwakusumah Edy Djauhari Purwakusumah Egra, Saat Eka Nurul Qomaliyah Enny Rimita Sembiring Erna Subroto Eva Harlina Fachrur Rizal Mahendra Fachrur Rizal Mahendra Fachrur Rizal Mahendra Fadila Raisyadikara Faiza, Lucky Lia Faizal Maulana Fajriansyah, Muhamad Renza Faris Adam Fina Febrianti Firmanul Hasan Fitria, Rizki Fransiska Devy Junardy Ghifari, Muhammad Nabil GIA PERMASKU Gultom, Milanda Fiorella Habibi, B Y Hamdan Hafizh Harahap Hamdan Hafizh Harahap Hanifah Aryani Harmanto, Ning Hartanti Hartanti Hartanti Hartanti Hartanti Hartanti, Hartanti Hayatul Rahmi Hyakansa Hyakansa I Made Artika I MADE ARTIKA Inawati Inawati Inda Setyawati, Inda Innes Maulidya Irmanida Batubara Jesajas, David Reinhard Juliana, Dara Junardy, Fransiska Devy Kamilah Da’inawari Khalissa Sekar Amanda Sudarjat Kilala Tilaar Kornelia Rosvita Manek Kunto Wibisono Kunto Wibisono Kunto Wibisono LAKSMI AMBARSARI Latifah K Darusman Latifah K Darusman latifah K Darusman Latifah K. Darusman Lelly Aulia Damarhati Lina Noviyanti Sutardi Lisnawati Tumanggor Liwanda, Novian Lucky Lia Faiza Luky Adrianto M, Kornelia Rosvita M. Agung Zaim Adzkiya M. Rafi Maily Mustofa Maria Bintang MARIA BINTANG Maria Magdalena Maulana, Asy Syifa Tickna Maulidya, Innes Mayang Anggita Cahya Kurnia Mayang Anggita Cahya Kurnia Milanda Fiorella Gultom Milanda Fiorella Gultom Mira Takene Mohamad Rafi Mono Rahardjo Muhamad Rizal Martua Damanik Muhamad Syukur Muhammad Maftuchin Sholeh Muhammad Musthofa Muhammad Riyo Agung Kurnia Mulyati, Teti Mustika Weni Mustofa, Maily Muthoharoh, Rini Najmah Najmah Najmah Najmah, Najmah Nella Angelina Simanjuntak Nelly Marliani Nevianti Zamany Ning Harmanto Norman Razief Azwar Novita Sari Nurul Khumaida Nurul Komala P.Roswiem, Anna Pebra Heriansyah Popi Asri Kurniatin Poppy F. Arifin Priyadi, Yogo Suro Puspa Julistia Puspita Putra, Raihan Permana Putri, Dita Audia Qomariyah, Eka Nurul Rachmi Ridho Rahmadansah Rahmadansah Raphael Aswin Susilowidodo Rara Annisaur Rosyidah Ratna Puspita Ratna Puspita, Ratna Rerenstradika Tizar Terryana Riki Riki Rikno Harmoko Rini Muthoharoh Rini Novita Riski Rostantinata Riti, Dominggus Ngongo Riyan Alifbi Putera Irsal Rizki Fitria Rizki Fitria Ros Sumarny Rosalina Wisastra Roswiem, Anna Priangani Rusmiyati, Henny Saat Egra Sadwika Najmi Kautsari Safira Khoirunnisa Safira Khoirunnisa Sandra Arifin Aziz Seliani Fitria Mukti Shobiroh Nuur' Alimah Sholeh, Muhammad Maftuchin Siahaan Rafael Siti Nur'aeni Sri Suhesti Sri Suhesti Sri Suhesti Sriwongo, Stephanie Subroto, Erna Sukma, Dewi Suryani Suryani Suryani Suryani Suryani Suryani Susilowidodo, Raphael Aswin Syamsul Falah Syarifah Iis Aisyah Takene, Mira Takeshi Katayama Taopik Ridwan Taufik Ridwan Taufik Ridwan Taufik Ridwan, Taufik Taureza, Aulia Tiara Rizky Utami Tilaar, Kilala Tony Sumaryada Toshisada Suzuki Tubagus Iqbal Maulana Tumanggor, Lisnawati Utami Dyah Safitri Weni, Mustika Wisastra, Rosalina Wulan Tri Wahyuni Wulansari, Laela Yogo Suro Priyadi Yoshua Shandy Yudha Yuliana Galih Dyan Anggraheni Yulianto Zamany, Nevianti