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All Journal Medula Juke Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Journal Syifa Sciences and Clinical Research (JSSCR) JURNAL MUTIARA KESEHATAN MASYARAKAT JK Unila (Jurnal Kedokteran Universitas Lampung) Indonesian Community Empowerment Journal Jurnal Pengabdian Masyarakat JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Muhammad Ricky Ramadhian
Fakultas Kedokteran, Universitas Lampung
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Identifikasi dan Uji Resistensi Staphylococcus aureus pada Ulkus Diabetik di Instalasi Penyakit Dalam RSUD Dr. H. Abdul Moeloek Rifda Khairunnisa; Tri Umiana Soleha; Muhammad Ricky Ramadhian
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 7 No. 1 (2020): Jurnal Kesehatan dan Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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Abstract

Staphylococcus aureus merupakan bakteri yang menyebabkan kerusakan jaringan disertai abses bernanah. Ulkus diabetik merupakan suatu ulserasi kronis pada kaki pasien diabetes melitus. Ulkus diabetik banyak disebabkan oleh bakteri Staphylococcus aureus dan Pseudomonas spp. Penelitian ini bertujuan untuk mengidentifikasi adanya S. aureus pada pasien diabetes melitus yang mempunyai ulkus diabetik. Penelitian ini adalah penelitian deskriptif menggunakan cross sectional study. Pengambilan sampel menggunakan metode non-probability sampling dengan jenis consecutive sampling dan alat ukur menggunakan nutrient broth. Hasil penelitian diuji dengan SPSS. Penelitian dilakukan terhadap 21 responden dengan 14 (66,7%) pasien positif S. aureus dan 7 (33,3%) pasien tidak terdapat S. aureus. Pola kepekaan antibiotik amoksisilin 92,9% resisten dengan 7,1% intermediate terhadap bakteri S. aureus, vankomisin 57,1% resisten dengan 42,9% sensitif, sefotaksim 50% resisten dengan 21,4% sensitif dan 28,6% intermediate serta sefoksitin memiliki tingkat resisten sebesar 42,9% dengan 57,1% sensitif terhadap S. aureus. Antibiotik yang paling sensitif adalah sefoksitin dan antibiotik yang paling resisten adalah amoksisilin.Kata kunci: Antibiotik, diabetes melitus, ulkus diabetikum.
Hubungan IMT Terhadap Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2: Tinjauan Pustaka Afifah, Ighra; Kurniati, Intanri; Marcellia, Selvi; Ramadhian, Muhammad Ricky
Medula Vol 15 No 4 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i4.1704

Abstract

Type 2 diabetes mellitus is a chronic metabolic disease with a steadily increasing prevalence globally, including in Indonesia. One of the main risk factors contributing to the development and severity of type 2 diabetes is obesity, clinically measured by Body Mass Index (BMI). Increased BMI is closely associated with impaired glucose metabolism and insulin resistance, which play a key role in the pathogenesis of type 2 diabetes. This study used a literature review approach by examining various studies analyzing the relationship between BMI and blood glucose levels. The results showed that increased BMI is positively correlated with fasting blood glucose, random blood glucose, and HbA1c levels. Individuals with a higher BMI tend to experience more severe glycemic control disorders. Pathophysiologically, increased adipose tissue, especially visceral fat, produces various inflammatory mediators such as TNF-α and IL-6, which disrupt the insulin signaling pathway, reduce glucose uptake by muscle tissue, and trigger hyperglycemia. Furthermore, dysfunction of adipokine hormones such as decreased adiponectin and resistance to leptin contribute to worsening insulin sensitivity
Laporan Kasus: Seorang Laki-Laki Usia 48 Tahun dengan Herniasi Nukleus Pulposus Servikal Fakhrizal, Muhammad Alka; Ramadhian, Muhammad Ricky; Wicaksono, Danang Samudro; Afrida, Frecilia; Ananda, Yovani Tria
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1801

Abstract

Cervical herniated nucleus pulposus is a common cause of neck pain, radicular pain, and neurological deficits resulting from compression of cervical nerve roots by intervertebral disc pathology. The incidence of cervical radiculopathy peaks in the fourth and fifth decades of life and is closely associated with degenerative disc changes. This report presents the case of a 48 year old male who complained of chronic neck pain radiating to the upper back and right upper extremity, accompanied by paresthesia, restricted cervical range of motion, and weakness during right arm elevation. The symptoms had persisted for one year and progressively worsened over the last two months, with no history of trauma. The patient also reported intermittent burning sensations that improved with rest. These clinical features were consistent with cervical radiculopathy caused by progressive cervical disc herniation. Magnetic resonance imaging of the cervical spine in sagittal sections revealed disc protrusion at the C5 C6 level causing anterior spinal canal compression, as well as mild disc protrusion at C6 C7 with narrowing of the anterior subarachnoid space. Thoracic spine MRI showed no significant abnormalities. Initial management consisted of conservative therapy using non steroidal anti inflammatory drugs and gabapentin to address inflammatory and neuropathic pain components. Due to persistent symptoms and motor weakness, surgical intervention with percutaneous endoscopic cervical discectomy was planned. A thorough understanding of cervical spine anatomy, disc herniation pathophysiology, clinical manifestations, and imaging findings is essential for accurate diagnosis and appropriate treatment selection to prevent symptom progression and deterioration of patient quality of life.
Laporan Kasus: Pemanfaatan MRI pada Diagnosis Fraktur Kompresi Vertebra Akut Post-Trauma Afrida, Frecilia; Ramadhian, Ricky
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1813

Abstract

Vertebral compression fracture (VCF) is a common spinal injury, particularly among the elderly population with underlying osteoporosis. This condition may lead to severe pain, functional limitation, spinal deformity, and increased morbidity and mortality if not accurately diagnosed and managed. A comprehensive clinical and radiological approach is essential to establish the diagnosis and to differentiate acute traumatic fractures from chronic or pathological vertebral fractures. Magnetic resonance imaging (MRI) plays a crucial role in the evaluation of vertebral compression fractures due to its superior ability to assess soft tissues, spinal cord involvement, and bone marrow edema, which is a key indicator of acute injury. This case report describes a 68-year-old male with a known history of osteoporosis who presented to the emergency department following a fall from a height. The patient complained of severe lumbar pain and limited mobility without neurological deficits. MRI examination revealed an acute vertebral compression fracture characterized by bone marrow edema, with no evidence of paraspinal soft tissue involvement or spinal cord compression. These findings confirmed the diagnosis of an acute post-traumatic VCF in an osteoporotic patient. This case highlights the pivotal role of MRI in determining fracture acuity, evaluating spinal stability, detecting potential complications, and guiding appropriate management strategies. The appropriate utilization of MRI may improve diagnostic accuracy, facilitate timely intervention, and ultimately enhance clinical outcomes in patients with vertebral compression fractures.
Hubungan Platelet–Lymphocyte Ratio dengan Luas Lesi Paru pada Pasien Tuberkulosis Paru di RSUD Abdul Moloek tahun 2023-2024 Ramadhian, Muhammad Ricky; Amertavia, Sindika; Fitri, Ayu Tiara; Mustofa, Syazili
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 12 No 3 (2026): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 12.3 (2026) : Article i
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v12i3.1021

Abstract

Background:. Pulmonary tuberculosis remains a major health problem and requires a simple marker to assess disease severity. The platelet-lymphocyte ratio (PLR) has been widely studied as an indicator of inflammation, but its relationship with lung lesion extent remains inconsistent. This study aimed to assess the relationship between PLR and lung lesion extent in pulmonary tuberculosis patients at Abdul Moloek Regional Hospital. Methods: This study used a cross-sectional design with a total sampling technique. A total of 52 patients who met the inclusion and exclusion criteria were analyzed. PLR data were obtained from complete blood counts, and lesion extent was assessed using chest radiography. Spearman correlation analysis was used to test the relationship between the two variables. Results: The distribution of lesion extent showed the largest proportion in the extent category. PLR values ??varied significantly between subjects. The Spearman test showed a correlation coefficient of 0.084 with a p-value of 0.553, indicating no significant relationship between PLR and lung lesion extent. Conclusion: This study concluded that PLR is not associated with lung lesion extent in pulmonary tuberculosis patients. PLR cannot be used as a radiological marker to assess the severity of lung damage, so additional parameters or a multimodal approach are needed in clinical evaluation
Hubungan Neutrophil Lymphocyte Ratio Dengan Derajat Keparahan Kellgren-Lawrence Pada Pasien Osteoartritis Lutit di RSUD Dr. H. Abdul Moeloek Ramadhian, Muhammad Ricky; Maharani, Melinda; Daulay, Suryani Agustina; Berawi, Khairun Nisa
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 12 No 3 (2026): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 12.3 (2026) : Article i
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v12i3.1020

Abstract

Background: Osteoarthritis (OA) is a chronic degenerative joint disease that causes pain, limited mobility, and reduced ability to perform daily activities. The severity of OA can be assessed radiologically using the Kellgren–Lawrence classification. One of the inflammatory markers used to evaluate inflammatory activity in OA is the Neutrophil Lymphocyte Ratio (NLR), which reflects the balance between neutrophils and lymphocytes. This study aimed to analyze the relationship between NLR and the radiological severity of knee osteoarthritis in female patients at Dr. H. Abdul Moeloek Hospital. Method: This study used a cross-sectional approach. The samples consisted of medical records of female patients diagnosed with knee osteoarthritis during the 2022–2025 period. Data were analyzed using univariate and bivariate analyses with the Spearman rank correlation test. Results: The Spearman test showed no significant relationship between NLR and the radiological severity of osteoarthritis (p=0.789; r=-0.041). Discussion: These findings indicate that NLR is not a dominant factor in determining the radiological severity of knee OA. This may be influenced by other factors, such as the involvement of various inflammatory mediators besides NLR and the locally limited nature of inflammation in OA. Conclusion: There was no significant relationship between NLR and the Kellgren–Lawrence radiological severity in female patients with knee osteoarthritis at Dr. H. Abdul Moeloek Hospital
HUBUNGAN NEUTROPHIL-TO-LYMPHOCYTE RATIO DENGAN DERAJAT HIPERTENSI DAN DERAJAT KARDIOMEGALI PADA PASIEN HIPERTENSI Ramadhian, Muhammad Ricky; Josephine, Felicia Key; Wardani, Nanda Fitri; Sangging, Putu Ristyaning Ayu
Jurnal Mutiara Kesehatan Masyarakat Vol 10 No 2 (2025): Jurnal Mutiara Kesehatan Masyarakat
Publisher : Program Studi Kesehatan Masyarakat Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jmkm.v10i2.6868

Abstract

Latar belakang: Hipertensi yang tidak terkontrol merupakan penyebab timbulnya berbagai komplikasi kardiovaskuler. Kardiomegali sering ditemukan pada pasien gagal jantung sebagai akibat dari hipertensi berat dan tidak terkontrol. Pada foto toraks disebut kardiomegali jika nilai cardiothoracic ratio lebih dari 50%, dan diklasifikasikan menjadi derajat ringan, sedang dan berat. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan NLR dengan derajat hipertensi dan derajat kardiomegali pada pasien hipertensi. Metode: Penelitian  ini bersifat deskriptik analitik dengan desain potong lintang. Variabel yang dianalisis adalah NLR dengan derajat hipertensi dan NLR dengan derajat kardiomegali. Hasil: Dari 31 subjek penelitian, sebagian besar berjenis kelamin perempuan sebesar 64,5%. Kelompok usia terbanyak adalah 59-64 tahun, yaitu sebesar 29%. Subjek penelitian didominasi oleh hipertensi derajat 1 dan derajat 2, masing-masing sebesar 45,2%. Nilai NLR minimum adalah 0,96 dan nilai maksimum 14,33 dengan simpangan baku 4,07. Uji korelasi Spearman menunjukkan nilai koefisien korelasi (r) sebesar 0,421 dengan signifikansi 0,021 (p<0,05) untuk hubungan NLR dengan derajat hipertensi, serta koefisien korelasi (r) sebesar 0,341 dan signifikansi 0,061 (p>0,05) untuk hubungan NLR dengan derajat kardiomegali. Kesimpulan: Terdapat hubungan yang positif dan signifikan antara NLR dengan derajat hipertensi, dan hubungan yang positif antara NLR dengan derajat kardiomegali walaupun tidak signifikan secara statistik.
Co-Authors Ade Marantika Adisti, Fransiska Afifah, Ighra Afrida, Frecilia Afriyani, Afriyani Akbar, Fareel Wahyu Amertavia, Sindika Ananda, Yovani Tria Anggraini, Dian Isti Aprina Adha Widiastini Asep Sukohar Atika Threenesia Balqis, Aurelia Corrinna Benny Bradley Pradana Pangaribuan Betta Kurniawan, Betta Daulay, Suryani Agustina Delvi Rusitaini Putri Diana Mayasari Efrida Warganegara Ekki Pirmansyah Ermin Rachmawati Ety Apriliana Ety Apriliana Fakhrizal, Muhammad Alka Falamy, Ryan Farhry Alvini Rahmania Fitri, Ayu Tiara Fitria, Aghniya Rizqy George Pestalozi Gultom, Dea Debora Romauli Hanna Mutiara, Hanna Hendra Tarigan Sibero Intanri Kurniati Iswandi Darwis Jhons Fatriyadi Suwandi Josephine, Felicia Key Khairil Pahmi Khairil Pahmi Khairun Nisa Kurniawaty, Evi Lusina, Septia Eva M Sidratullah MAHARANI, MELINDA Marcellia, Selvi Meta Gapila Muhammad Maulana Muhammad Taupik Nadhifa, Farin Nasution, Salwa Salsabila Nora Ramkita Novita Carolia Nurul Sahana Rahmadhini Nurul Utami Oktadoni Saputra, Oktadoni Putri, Abrila Tamara Ratna, Maya Ganda Reni Zuraida Rifda Khairunnisa Rika Lisiswanti Risti Graharti Sangging, Putu Ristyaning Ayu Septiani, Linda Shinta Nareswari, Shinta Suryadi Islami Sutarto Sutarto Syafira Salsabila Syazili Mustofa Tri Umiana Sholeha Tri Umiana Soleha Tri Umiana Soleha Wardani, Nanda Fitri Wicaksono, Danang Samudro Yuniarti, Wulan Yuningrum, Hesti