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Pengendalian Penyakit Rabies melalui Media Komunikasi, Informasi, dan Edukasi kepada Masyarakat di Kota Padang Shila Rahmafia Putri; Agus Setiyono
Jurnal Pusat Inovasi Masyarakat (PIM) Vol. 2 No. 2 (2020): April 2020
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Institut Pertanian Bogor

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Abstract

Rabies is a zoonotic disease caused by a virus belonging to the Lyssa virus and the family of Rhabdoviridae. Rabies becomes an endemic to 24 of 34 province in Indonesia, including West Sumatera. This condition makes rabies becomes a priority for the Indonesian goverment. Another way to control the spread of this disease beside a vaccination is through a counseling to the community with a media of communication, information, and education (CIE) about rabies. The CIE about rabies activity aims to educate the community about the dangers of rabies and the measures that could be taken if someone is being bitten by a rabies infectious animal. The CIE about rabies activity in Padang are carried out through two-way communication with posters, rabies games boards, and zoonotic knowledge books. This activity was attended by 1471 participants from various professions in the city of Padang. Through this activity, the community got information about the dangers of rabies, the characteristics of animals that infected with rabies, how rabies is transmited, and the steps for handling if someone is bitten by a rabies infectious animal. Keywords: CIE, Padang city, rabies
Pelaksanaan Vaksinasi Rabies pada Anjing dan Kucing Kecamatan X Koto Singkarang, Kabupaten Solok, Sumatera Barat Mohammad Irham Bagus Santoso; Agus Setiyono
Jurnal Pusat Inovasi Masyarakat (PIM) Vol. 2 No. 2 (2020): April 2020
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Institut Pertanian Bogor

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Abstract

Rabies vaccination has been carried out on dogs and cats in Nagari Tikalak, District X Koto Singkarak, Solok Regency, West Sumatra. Vaccination is held on Wednesday, July 17, 2019 in Tiga Jorong namely Jorong Pasir, Jorong Tengah, and Jorong Batu Api, Nagari Tikala. The purpose of vaccination is to prevent transmission of the rabies virus by rabies-transmitting animals. Rabies vaccination was carried out by one veterinarian, three FKH IPB students and four paramedics. Vaccination is done by going directly to the homes of residents who have dogs and cats. Implementation of rabies vasination has been carried out to prevent transmission of rabies to the community. Vaccination was carried out on 27 dogs and 13 cats. Keywords: cats, dogs, nagari tikalak, rabies vaccination
Vaksinasi Newcastle Disease pada Peternakan Ayam Buras di Kabupaten Agam Sumatera Barat Muhammad Zuhdi Badruzzaman; Mochamad Alfinanda Santriagung; Agus Setiyono
Jurnal Pusat Inovasi Masyarakat (PIM) Vol. 2 No. 2 (2020): April 2020
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Institut Pertanian Bogor

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Abstract

Tetelo or Newcastle disease (ND) is a strategic infectious viral disease that is endemic in Indonesia. Prevention of these diseases by vaccinating poultry as a source of infectious disease. One of the vaccines used for tetelo repeat vaccination is the active tetelo (ND) active vaccine. Active ND vaccine is a vaccine in the frozen dried form which each dose contains 108 EID50 viruses. Repeated vaccination is carried out to trigger secondary antibody responses in native chickens in order to achieve a protective antibody titer against tetelo. One of them is people's fights in Agam Regency, West Sumatera with a population of 184 village chicken. The purpose of the activity is to prevent ND disease (Newcastle disease) on community farms. Vaccination is done by making sometimes where chickens are vaccinated and making nets around the cage. Vaccination results have reached the target of 90% of the chicken population in these farmers. The impact of vaccination will be seen 2-3 days after the vaccination is carried out. The population immunity from chickens from breeders will increase. A factor in the occurrence of ND (Newcastle Desease) due to the close distance between the chicken coop and other poultry cages. Keywords: newcastle desease, vaccination, village chicken
Edukasi Masyasrakat dalam Mengurangi Rabies Serta Peningkatan Kesehatan Ternak melalui Pemeriksaan Masal pada Lima UPT di Kabupaten Agam, Sumatera Barat Arif Yahya; Muhammad Ihsan; Alvin Jefry; Agus Setiyono
Jurnal Pusat Inovasi Masyarakat (PIM) Vol. 2 No. 2 (2020): April 2020
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Institut Pertanian Bogor

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Abstract

Rabies is a deadly disease transmitted from animals to humans with more than 59,000 people recorded or almost 1 death every 9 minutes CDC (2017). The main source of transmitting rabies is dogs through bites and saliva which contain viruses. Rabies is a strategic infectious animal disease (PHMS) whose existence is prioritized to be controlled in Indonesia. West Sumatra Province is still an area that is not yet free of rabies with extraordinary events (KLB). Aside from rabies, the biggest challenge is the many diseases of Jembrana. Jembrana is a strategic disease with its main host being only Bali cattle (Bos sondaicus). Decreased immune system cells (B lymphocytes) will cause the development of bacteria in the body's organs or sekuder infection (Directorate of Animal Health 2015). Thus causing losses including livestock mortality, declining health and quality of livestock, disruption of activities involving cattle, to the loss of closure of the affected area. Implementation of activities in the form of socialization and education about rabies, rabies vaccination, and mass animal health checks. The results of the field show that the number of treatments for livestock is 931, HPR vaccination, 1,211 and 859 people have received socialization regarding the spread of rabies in 5 UPTs in Agam District. Education and assistance are given to the public about the importance of eradicating rabies. The spread of jembrana disease can be inhibited by using vaccines through mass treatment programs. Key words: education, livestock, rabies, vaccines
Hepatoprotective Activity of Propolis Trigona spp., Hibiscus sabdariffa, and Myrmeleon sp. in Rats Induced by Paracetamol Akhmad Endang Zainal Hasan; Agus Setiyono; Miko Afrian
Current Biochemistry Vol. 9 No. 1 (2022)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.9.1.4

Abstract

Negative effects on health will occur in excessive use of paracetamol. The main objective of this study was to determine the hepatoprotective activity of Propolis Trigona spp., Hibiscus sabdariffa, and Myrmeleon sp. in rats induced by paracetamol. The study was conducted on 36 Sprague Dawley rats with 6 rats in each group. Group 1 (normal control), group 2 (positive control, temulawak 42.86 mg/kg BW), group 3 (negative control), group 4 (infusion of Myrmeleon 10 mg/kg BW), group 5 (propolis extract 0.02 ml/kg BW), and group 6 (Hibiscus sabdariffa infusion 0.02 ml/kg BW). Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations were determined spectrophotometrically and microscopically for liver histopathology. The results showed that during three weeks of treatment with Propolis Trigona spp., Hibiscus sabdariffa, and Myrmeleon sp. in rats, this treatment could decrease ALT and AST activity as the positive control. The ALT activity values ​​of the three materials were 69.26, 51.00, 51.00, 43.67, U/I with AST values ​​of 110.29, 97.33, 91.00, 91.33 U/I. Based on Duncan's test, there were significant differences between all treatments with negative and positive control groups. Likewise, with the histopathological scoring results, the negative control was found to be significantly different from all treatments. Therefore, treatment with propolis Trigona spp., Hibiscus sabdariffa, and Myrmeleon sp. may have hepatoprotective benefit.
DETEKSI IMUNOHISTOKIMIA ANTIGEN Coxiella burnetii SEBAGAI PENYEBAB Q FEVER PADA SAPI Sangko Sayuti Nasution; Agus Setiyono; Ekowati Handharyani
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.745 KB) | DOI: 10.21157/j.ked.hewan.v9i2.2835

Abstract

Penelitian ini bertujuan mendeteksi keberadaan antigen Coxiella burnetii sebagai penyebab Q fever pada organ sapi yang dikumpulkan di rumah potong hewan (RPH) Kota Medan dan Kabupaten Deli Serdang. Pada penelitian ini telah dikumpulkan organ limpa, paru-paru, dan hati dari 162 ekor sapi. Sampel organ tersebut kemudian diperiksa secara imunohistokimia dengan metode streptavidin peroksidase untuk melihat keberadaan antigen Coxiella burnetii menggunakan antibodi poliklonal terhadap Coxiella burnetii. Hasil pemeriksaan imunohistokimia menunjukkan 62/162 (38,3%) sampel sapi imunoreaktif terhadap Coxiella burnetii. Berdasarkan asal pengambilan sampelnya, sebanyak 40/101 (39,6%) sampel sapi yang berasal dari RPH Kota Medan dan 22/61 (36,1%) sampel sapi yang berasal dari RPH di Kabupaten Deli Serdang menunjukkan hasil imunoreaktif. Dilihat dari jenis organnya, dari 162 sampel sapi, antigen Coxiella burnetii dapat dideteksi pada 61 (37,7%) organ limpa, 12 (7,4%) organ paru-paru dan 2 (1,2%) organ hati. Hasil ini menunjukkan telah adanya infeksi Coxiella burnetii pada sapi di Kota Medan dan Kabupaten Deli Serdang.
GAMBARAN HISTOPATOLOGIS DAN KLINIS AYAM HERBAL SETELAH DIUJI TANTANG DENGAN VIRUS AVIAN INFLUENZA H5N1 Agus Setiyono; Nurliani Bermawie
Jurnal Kedokteran Hewan Vol 8, No 1 (2014): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.485 KB) | DOI: 10.21157/j.ked.hewan.v8i1.1252

Abstract

Tujuan penelitian ini adalah mengetahui perubahan histopatologis dan klinis ayam herbal setelah ditantang dengan virus avian influenza (AI) H5N1. Seluruh ayam dibagi atas 3 kelompok perlakuan Kelompok kontrol, Kelompok I (I-1, I-2, dan I-3), dan Kelompok II (II-1, II-2, dan II-3). Masing-masing kelompok terdiri atas 15 ekor ayam sehingga jumlah seluruh ayam yang digunakan adalah 105 ekor. Ayam Kelompok I dan II masing-masing diberi herbal I (sambiloto, temu ireng, adas bintang, sirih merah) dan herbal II (sambiloto, adas bintang, sirih merah) selama 3 minggu sebelum ditantang virus. Ayam kelompok perlakuan secara keseluruhan tidak ada yang hidup hingga hari ke-8. Hasil penelitian menunjukkan bahwa 7 ekor ayam KII-3 (46,7%) masih hidup sampai hari ke-4 setelah uji tantang virus. Perubahan histopatologis sistem pernafasan ayam kelompok perlakuan menunjukkan pembendungan, edema, dan kerusakan sel epitel mukosa. Sistem limfoid juga menunjukkan pembendungan, deplesi folikel limfoid, dan fibrosis limpa dan bursa Fabrisius. Analisis imunohistokimia mengindikasikan partikel virus AI telah menyebar di organ atau jaringan sistem pernafasan dan sistem pertahanan.
DETEKSI IMUNOHISTOKIMIA ANTIGEN Coxiella burnetii SEBAGAI PENYEBAB Q FEVER PADA SAPI Sangko Sayuti Nasution; Agus Setiyono; Ekowati Handharyani
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v9i2.2835

Abstract

Penelitian ini bertujuan mendeteksi keberadaan antigen Coxiella burnetii sebagai penyebab Q fever pada organ sapi yang dikumpulkan di rumah potong hewan (RPH) Kota Medan dan Kabupaten Deli Serdang. Pada penelitian ini telah dikumpulkan organ limpa, paru-paru, dan hati dari 162 ekor sapi. Sampel organ tersebut kemudian diperiksa secara imunohistokimia dengan metode streptavidin peroksidase untuk melihat keberadaan antigen Coxiella burnetii menggunakan antibodi poliklonal terhadap Coxiella burnetii. Hasil pemeriksaan imunohistokimia menunjukkan 62/162 (38,3%) sampel sapi imunoreaktif terhadap Coxiella burnetii. Berdasarkan asal pengambilan sampelnya, sebanyak 40/101 (39,6%) sampel sapi yang berasal dari RPH Kota Medan dan 22/61 (36,1%) sampel sapi yang berasal dari RPH di Kabupaten Deli Serdang menunjukkan hasil imunoreaktif. Dilihat dari jenis organnya, dari 162 sampel sapi, antigen Coxiella burnetii dapat dideteksi pada 61 (37,7%) organ limpa, 12 (7,4%) organ paru-paru dan 2 (1,2%) organ hati. Hasil ini menunjukkan telah adanya infeksi Coxiella burnetii pada sapi di Kota Medan dan Kabupaten Deli Serdang.
GAMBARAN HISTOPATOLOGIS DAN KLINIS AYAM HERBAL SETELAH DIUJI TANTANG DENGAN VIRUS AVIAN INFLUENZA H5N1 Agus Setiyono; Nurliani Bermawie
Jurnal Kedokteran Hewan Vol 8, No 1 (2014): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v8i1.1252

Abstract

Tujuan penelitian ini adalah mengetahui perubahan histopatologis dan klinis ayam herbal setelah ditantang dengan virus avian influenza (AI) H5N1. Seluruh ayam dibagi atas 3 kelompok perlakuan Kelompok kontrol, Kelompok I (I-1, I-2, dan I-3), dan Kelompok II (II-1, II-2, dan II-3). Masing-masing kelompok terdiri atas 15 ekor ayam sehingga jumlah seluruh ayam yang digunakan adalah 105 ekor. Ayam Kelompok I dan II masing-masing diberi herbal I (sambiloto, temu ireng, adas bintang, sirih merah) dan herbal II (sambiloto, adas bintang, sirih merah) selama 3 minggu sebelum ditantang virus. Ayam kelompok perlakuan secara keseluruhan tidak ada yang hidup hingga hari ke-8. Hasil penelitian menunjukkan bahwa 7 ekor ayam KII-3 (46,7%) masih hidup sampai hari ke-4 setelah uji tantang virus. Perubahan histopatologis sistem pernafasan ayam kelompok perlakuan menunjukkan pembendungan, edema, dan kerusakan sel epitel mukosa. Sistem limfoid juga menunjukkan pembendungan, deplesi folikel limfoid, dan fibrosis limpa dan bursa Fabrisius. Analisis imunohistokimia mengindikasikan partikel virus AI telah menyebar di organ atau jaringan sistem pernafasan dan sistem pertahanan.
MOLECULAR DETECTION OF Coxiella burnetii THE CAUSE OF ZOONOSIS Q FEVER IN VARIOUS ORGANS OF CATTLE IN BANDUNG REGENCY Tsulatsy Puspitasari Purnamiharja; Vetnizah Juniantito; Rahayu WoroWiranti; Agus Setiyono
Jurnal Kedokteran Hewan Vol 17, No 3 (2023): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v17i3.32716

Abstract

Primary objective of this study was to ascertain the presence of Coxiella burnetii (C. burnetii) as the causative of Q fever in cattle within Bandung Regency. Tissue samples were procured from 240 slaughtered cattle’s in abattoirs across Bandung Regency. Each breed of cattle consists of Brahman cross (BX), Simmental, Limousin, Friesien Holstein crossbreed, and Friesien Holstein (FH) with total of 192, 3, 13, 29, and 3, respectively. Detection method employed was nested-Polymerase Chain Reaction (PCR) to identify the presence of C. burnetii Deoxyribonucleic Acid (DNA) within tissue samples. Positive samples underwent further examination employing hematoxylin-eosin (HE) staining to identify lesions attributed to C. burnetii. Five BX cattle were identified as positive for C. burnetii in lungs and heart.  However, histopathological analysis of both organs did not reveal any notable changes. These findings suggest the occurrence of C. burnetii infection in cattle within Bandung Regency, without specific histopathological changes indicative of Q fever lesions. In conclusion, presence of asymptomatic C. burnetii infections should be regarded as a significant threat to human health.
Co-Authors Aditya Dharmawan, Aditya Aditya Wahyu Nugraha Afifah, Amalia Aisjah Girinda Akhmad Endang Zainal Hasan Akterono D. Budiyati Allaily Allaily Altaff Hendry Alvin Jefry Amrozi Andriyanto . Anita Esfandiari Arif Yahya Ario Damar Aulia Dina Kristina Bayu Sandi Chintia Ayu Puspita Daniel Latief Andre Darsono Darsono Desdiani Diah Nugrahani Pristihadi Dian Maulia Utami Dian Pratiwi DIMAS ANDRIANTO Dinar Arifianto Djumali Mangunwidjaja Dwi Astuti E. Mulyati Effend Effend, E. Mulyati Eko Prasetyo Nugroho Eko Suryanto Ekowati Handharyani Elok Puspita Rini Elpita Tarigan Eny Nur Aisyah Evy Damayanthi Fachriyan Hasmi Pasaribu Feri Kusnandar Gani, Ainal Gatut Ashadi Handayu Untari Handayu Untari Hanif Alamudin Manshur Hapsari Mahatmi Hardika Hardika, Hardika Hasim Hasim Hasim Hasim Hasim Hasim Hasim Hasim, . Hirawan Setiadi Husnawati, . I Ketut Suada I Komang Gede Wiryawan I wayan Teguh Wibawan Idqan Fahmi Ike Agustiani IPB, DGB Iris Rengganis Ismah Atika Salmah Japanis Permatasari, Retno Jusman, Sri Widia Azraki Kustiariyah Tarman Lala M Kolopaking Liesbetini Haditjaroko Lily Natalia M Agus Setiadi M. Aman Yaman M. Misbah, M. Ma'mun Sarma Maharani Maharani Maningtyas, Rosyidamyani Twinsari Masdiana C. Padaga Mega Safithri Miko Afrian Mochamad Alfinanda Santriagung Mohammad Irham Bagus Santoso Mohammad Sadikin Muhammad Daud Muhammad Ihsan Muhammad Luthfi Rahman Muhammad Ridla Muhammad Zuhdi Badruzzaman Muhammad Zulkifli Muharam Saepulloh Mutholaah Nadine Hanifa Permana Nahrowi Nahrowi Nahrowi Nathasia, Novena Neni Nuryani Nina Herlina Noviasari, Santi Nurjati Chairani Siregar Nurliani Bermawie Nurliani Bermawie Nurrahman, Arif Oktariza, Wawan Olive Wisepti Pratama Ono Suparno Pribadi, Yohanes Kusuma Purwiyatno Hariyadi Putri C. Eyanoer Rachmat Nabib Rahayu WoroWiranti Rahminiwati, Min Rayendra, Raendi Restu Librani Retno Damayanti Soejoedono Risa Tiuria Samsuridjal Djauzi Sandi, Bayu Sangko Sayuti Nasution Sekar Winahyu Ariadini Shila Rahmafia Putri SILMI MARIYA Siti Zulaikhah Slamet Budijanto Sri Purwaningsih, Sri Sri Wahyuni Salam Sudradjat Sumiati Suradi Suria Darma Tarigan Syahruddin Said Syifa Khaerani Teo Qin Yan Titi Candra Sunarti Tomas Iriyanto Tri Isyani Tungga Dewi Trioso Purnawarman Tsulatsy Puspitasari Purnamiharja Ulfah Juniarti Siregar Unang Patriana Upik Kesumawati Hadi Utamimah, Sri Vetnizah Juniantito Win Satya Rudramurti Winahyu Ariadini, Sekar Wiranda G Piliang Wiwin Winarsih Wiyono, W. Yeni Kartika Sari, Yeni Kartika