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All Journal Journal of Food and Pharmaceutical Science Jurnal Sain Veteriner Jurnal Pendidikan Indonesia Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Sains dan Teknologi Farmasi JURNAL ILMIAH PENDIDIKAN FISIKA AL BIRUNI Pharmacon Majalah Obat Tradisional Acta Pharmaciae Indonesia : Acta Pharm Indo Farmasains : Jurnal Ilmiah Ilmu Kefarmasian WIDYA LAKSANA PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) FITOFARMAKA: Jurnal Ilmiah Farmasi Jurnal Komunikasi Pendidikan Optika : Jurnal Pendidikan Fisika Jurnal Insan Farmasi Indonesia AL-KHAZINI: JURNAL PENDIDIKAN FISIKA Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Journal of Food and Pharmaceutical Sciences Borneo Journal of Pharmacy
Wahyu Widyaningsih
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Veterinary Other

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Application Of Problem Solving Learning Model Through Lesson Study On Critical Thinking Ability Of Students At Yabt Manokwari Kristen High School Astutik, Novita Santi; Widyaningsih, Sri Wahyu; Sinon, Iriwi L.S.
Al-Khazini Vol 3 No 1 (2023): April
Publisher : UIN Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-khazini.v3i1.33818

Abstract

This study aims to see the implementation of the problem solving learning model based on lesson study and to see the students' critical thinking skills and student responses after learning with the problem solving model. This research was conducted at the YABT Christian High School Manokwari in the 2021/2022 academic year. This research is a lesson study research with research subjects in class X IPA totaling 14 students. The research data collection technique used was a test in the form of critical thinking questions, non-test in the form of a response questionnaire to the learning model and activity observation sheets. The data analysis technique used is descriptive qualitative analysis, descriptive analysis of critical thinking, and questionnaire response analysis to the learning model using Rasch modeling. The research data were obtained from the results of observation sheets, critical thinking questions and questionnaire responses to the learning model. The results of the implementation of lesson study during the learning cycle I and cycle II showed that learning activities were well observed and showed good student responses, and increased critical thinking skills, seen from the results of tests and observations of observers. The critical thinking ability of students in solving problems is known through thinking analysis where the value of the 4 indicators is included in the sufficient criteria with an average value of 49.92. Then the results of the student response questionnaire in general indicate that in general students have a good response to learning.
PENERAPAN MODEL PEMBELAJARAN BERBASIS MASALAH BERBANTUAN SIMULASI PhET UNTUK MENINGKATKAN HASIL BELAJAR DAN AKTIVITAS FISIKA DI SMAS ADVENT MANOKWARI Widyaningsih, Sri Wahyu; Rumansara, Tamariska Herlindo; Yenusi, Kaleb Amaghi
OPTIKA: Jurnal Pendidikan Fisika Vol. 8 No. 1 (2024): OPTIKA: Jurnal Pendidikan Fisika
Publisher : Department of Physics Education, Faculty of Teacher Training and Education, Universitas Flores

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/optika.v8i1.3383

Abstract

Penelitian ini bertujuan untuk mengkaji penerapan model pembelajaran berbasis masalah (PBL) yang didukung simulasi PhET serta mengkaji hasil belajar dan aktivitas belajar siswa. Penelitian ini dilaksanakan di SMAS Advent Manokwari pada semester genap 2022/2023. Jenis penelitian ini adalah penelitian tindakan kelas (PTK) dengan subjek penelitian kelas X IPA yang berjumlah 23 siswa. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah tes berupa soal pretest-posttest dan nontes berupa lembar observasi. Teknik analisis data yang digunakan adalah analisis deskriptif kualitatif, analisis deskriptif hasil belajar, dan analisis aktivitas belajar siswa. Pada siklus I nilai rata-rata sebesar 52 dan pada siklus II sebesar 90. Daya serap klasikal siswa pada siklus I sebesar 50% dan pada siklus II sebesar 87,5%. Ketuntasan belajar siswa pada siklus I sebesar 50% dengan kriteria tuntas, dan pada siklus II sebesar 87,5% dengan kriteria tuntas. Pada tindakan pertama nilai rata-rata sebesar 52 dan pada tindakan kedua sebesar 90. Kemampuan serapan klasikal siswa pada tindakan pertama sebesar 50% dan pada tindakan kedua sebesar 87,5%. Tingkat ketuntasan akademik siswa pada siklus I sebesar 50% yang tidak memenuhi kriteria, dan pada siklus II sebesar 87,5% yang tidak memenuhi kriteria. Begitu pula dengan peningkatan aktivitas belajar siswa selama proses pembelajaran, dibuktikan dengan nilai rata-rata aktivitas siswa khususnya pada aktivitas pertama sebesar 15,33 atau 47,92% tergolong cukup baik, sedangkan pada aktivitas kedua nilai rata-ratanya meningkat menjadi 21 atau 65,63% dalam kategori baik. Oleh karena itu, dapat disimpulkan bahwa penerapan model PBL yang didukung simulasi PhET dapat meningkatkan hasil belajar dan aktivitas belajar siswa Kelas X IPA SMAS Advent Manokwari pada mata pelajaran fisika.
Effects of Fermented Red Rice Bran on Gut Microbiota Modulation and Colorectal Cancer Prevention in a DMBA-Induced Mouse Model Anasyua, Fairuz Khairunnisa; Cahya, Sella Nur; Hanifah, Azka Khansa; Kusuma, Rio Jati; Rahmawati, Dini; Widyaningsih, Wahyu
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.20690

Abstract

Colorectal cancer prevention is closely linked to gut microbiota modulation, particularly by increasing lactic acid bacteria (LAB) and short-chain fatty acids (SCFA). This study investigates the effect of fermented red rice bran on colon microbiota improvement. Fermented bran was produced by mixing red rice bran with water and yeast, followed by an analysis of the proximate composition, dietary fiber, resistant starch, antioxidants, and phenols. A quasi-experimental study was conducted on 30 mice, assigned to normal, negative control, 10% bran, 20% bran, 10% fermented bran, and 20% fermented bran groups. Colorectal cancer was induced using DMBA (20 mg/kgBW) intraperitoneally four times over two weeks. Treatment groups received bran or fermented bran ad libitum for 14 days. Cecal analysis showed that 20% red rice bran and 10% fermented bran significantly increased SCFA levels (p < 0.05), suggesting improved microbiota function, but did not significantly alter pH or LAB counts. These findings highlight the potential of fermented red rice bran in modulating gut microbiota, though further studies are needed to elucidate its long-term effects and mechanisms in colorectal cancer prevention.
Quantitative Determination of Flavanone Content in Teki Grass Tuber (Cyperus rotundus L) using Ultraviolet-Visible Spectrophotometry Fitriyati, Laeli; Nurani, Laela Hayu; Utami, Dwi; Widyaningsih, Wahyu
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.21526

Abstract

Teki grass (Cyperus rotundus L.) tubers are medicinal plants that have been widely utilized for their anti-inflammatory, antioxidant, antibacterial, and anticancer properties. These pharmacological activities are attributed to the presence of polyphenolic compounds, particularly flavanones. This study aims to determine the flavanone content in teki grass tubers using UV-Vis spectrophotometry. The research was conducted as a laboratory-based experimental study, involving several steps: sample preparation, simplisia processing, extraction, and quantitative analysis of flavanone content by comparison with a flavanone standard. The UV-Vis spectrophotometric analysis revealed the presence of flavanones in the extract of teki grass tubers. Quantitative results showed that the flavanone concentration in the extract was 128.29 µg/mL. These findings confirm that teki grass tubers are a potential natural source of flavanones, supporting their traditional herbal medicine use.
Pengaruh Pemberian Ekstrak Etanol Kulit Buah Jeruk Baby (Citrus sinensis L. Osbeck) Selama 28 hari terhadap Kadar SGOT dan SGPT Sofia, Vivi; Widyaningsih, Wahyu; Yuliani, Sapto; Bachri, Moch Saiful
Jurnal Sain Veteriner Vol 42, No 2 (2024): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.71513

Abstract

One of the plants used as natural medicine is baby orange (Citrus sinensis L. Osbeck). Baby oranges contain hesperidin, hesperetin, narirutin and nobiletin compounds. The purpose of this study was to determine the effect of giving ethanol extract of baby orange peel for 28 days on liver function as seen from the increase in SGOT and SGPT levels. This research is a pure experimental study with a completely randomized design (CRD) with a unidirectional pattern, namely the method used to observe the relationship of independent variables (including: normal control, negative control, ethanol extract of baby orange peel (EEKBJB) doses of 50, 100, 200 and 400 mg/kg BW) with the dependent variable (SGOT and SGPT levels). The test animals used in this study were 30 male Wistar rats which were divided into 6 treatment groups which were treated for 28 consecutive days. On day 29, blood samples were taken from the orbital sinus of the eye and the levels of SGOT and SGPT were measured. There was a significant difference in the levels of SGOT and SGPT as indicated by the results of the One Way ANOVA test (p<0.05). The results of the Post Hoc-Tukey test for SGOT levels showed a significant difference between the control group and the 50 mg/kg BW dose group, while the 100, 200 and 400 mg/kg BW doses did not show a significant difference. The results of the Post Hoc-Tukey, s-HSD test for SGPT levels did not show a significant difference between the control group and the 50, 100, 200 and 400 mg/kg BW dose groups. Significant differences were shown by doses of 50 and 400 mg/kg BW. Giving EEKBJB for 28 days did not cause toxic effects on liver function, seen from the absence of an increase in SGOT and SGPT levels.
PROFIL KANDUNGAN FENOLIK DAN EVALUASI PARAMETER NON-SPESIFIK EKSTRAK ETANOL RIMPANG JAHE MERAH (Zingiber officinale var. rubrum) Sundari, Trias Kania; Bachri, Moch. Saiful; Laela Hayu Nurani; Wahyu Widyaningsih; Muhammad Ma'ruf
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/wpv2vp92

Abstract

Jahe merah (Zingiber officinale var. rubrum) merupakan tanaman obat yang diketahui memiliki aktivitas antiinflamasi dan antioksidan. Penelitian ini bertujuan untuk menstandarisasi ekstrak etanol jahe merah melalui penentuan kandungan fenolik total dan parameter non-spesifik. Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 75% selama 1x24 jam. Kandungan fenolik total dianalisis dengan menggunakan metode Follin-Ciocalteu dan hasilnya dinyatakan dalam satuan mg GAE. Parameter non-spesifik yang ditentukan meliputi kadar air, kadar abu, dan kadar sari larut etanol dengan metode gravimetri. Hasil analisis menunjukkan ekstrak etanol jahe merah memiliki kadar air sebesar 12,87%, kadar abu 7,45%, kadar sari larut etanol 6,23% dan kandungan fenolik total sebesar 136,7mg GAE/g ekstrak. Data ini memberikan dasar ilmiah untuk standarisasi ekstrak jahe merah sehingga dapat digunakan sebagai bahan baku produk farmasi dengan mutu yang terukur.
Effect of Avocado Leaf Ethanol Extract Gel (Persea americana Mill) on Healing Diabetic Wounds Widyaningsih, Wahyu; Yuliani, Sapto; Anasyua, Fairuz Khairunnisa; Bahagia, Tasya; Yuliawanti, Risma
Journal of Food and Pharmaceutical Sciences Vol 14, No 2 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.25562

Abstract

Diabetic wounds are a major clinical challenge due to delayed healing and increased complication risks. Ethanol extract of avocado leaves (Persea americana Mill.) has previously shown promise in enhancing tissue regeneration in diabetic wounds, but its potential in gel form remains untested. This study aimed to develop an avocado leaf ethanol extract-based gel and evaluate its woundhealing potential in diabetic mice. Avocado leaves were extracted using 70% ethanol and formulated into a gel, which was evaluated for physical properties and topical suitability. Diabetic mice were divided into five groups: normal control, negative control (gel base), positive control (bioplacenton), and two treatment groups (5% and 10% gel). Diabetes was induced using alloxan (150 mg/kg BW), followed by wound induction and treatment. Wound healing was assessed through visual assessment, wound diameter reduction, and healing duration. Statistical analysis was performed using one-way ANOVA with a 95% confidence level. Results showed the gel meets physical properties (pH test, organoleptic test, homogeneity test, spreadability test) and significantly improved wound healing in diabetic mice. The 5% gel demonstrated wound-healing activity due to bioactive compounds such as saponins, tannins, alkaloids, and flavonoids. Further analysis is needed to identify the specific components responsible for the healing effects, highlighting the gel’s potential for diabetic wound treatment.
Co-Authors Aditya Prabowo Aditya Prabowo Ainiyah, Nadia Putri Aldri Frinaldi Anasyua, Fairuz Khairunnisa Astutik, Novita Santi Ayu Wulandari Azis Ikhsanudin Bachri, Mochammad Saiful Bahagia, Tasya Br. Sebayang, Sri Rosepda Cahya, Sella Nur Danang Prasetyaning Amukti Dara Pranidya Tilarso Daru Estiningsih Dedi Kuswandi Desi Iswahyuni Desyandri Desyandri Dini Rahmawati Dwi Fitriani Dwi Utami Erliyana, Mila Eti Nurwening Sholikhah Fadilah, Nur Aini fatima, fatma Fauzi, Muh Fajar Fitriyati, Laeli Galang Pergiawan Ramadhan Hanifah, Azka Khansa Hari Susanti Iin Narwanti Iis Wahyuningsih Indra Primardiana, Indra Irfan Yusuf Iriwi L.S Sinon, Iriwi L.S Iriwi L.S. Sinon, Iriwi L.S. Istyarini Istyarini, Istyarini Jumina Jumina Jumina Jumina Kaffah, Silmi Kusuma, Rio Jati Laela Hayu Nurani Laela Hayu Nurani Lalu Muhammad Irham M. Paden, Thereziana Moch Saiful Bachri Moch. Saiful Bachri Moch. Saiful Bachri Muhammad Ma'ruf Muhammad Ma'ruf Muhammad Yusron Maulana El-Yunusi Mujasam Mujasam Nina Salamah Nisa Isneni Hanifa Nur Asih, Nur Nurliawaty, Lilis Pramono, Suwidjiyo Primardiana, Indra Puteriragil Atma Pertiwi, Puteriragil Atma Radjab Sutrisno, Radjab Rerung, Nensy Rezza Wahyudi Rifka Salsabila Riska Riska Riza Sativa, Riza Rumansara, Tamariska Herlindo Ryan Syahputra Sapto Yuliani Sapto Yuliani Sativa, Riza Septianingsih, Ulfah Silmi Kaffah Siswanti Siswanti Sitarina Widyarini Siti Fatmawati Fatimah, Siti Fatmawati Sri Rosepda Sebayang, Sri Rosepda Suci Kurniati Sugiyanto - Sugiyanto, Sugiyanto Sumiasih Sumiasih Sundari, Trias Kania Suwidjiyo Pramono Tirza Pangkali, Tirza Ulfah Septianingsih Vivi Sofia Wiki Yuli Anita Wulandari, Silviana Wulandari, Silviana Wulansari, Widyanari Febriyana Wumu, Dea Anggrainy Y.T. Allo, Alberto Yenusi, Kaleb Amaghi Yoga Yuniadi Yuliawanti, Risma