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All Journal Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Sari Pediatri Paediatrica Indonesiana Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Human Care Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Indonesian Journal of Electrical Engineering and Computer Science Science Midwifery Indonesian Journal of Global Health research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal EduHealth Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Ilmu Kesehatan Masyarakat Indonesian Journal of Advanced Research (IJAR) Proceeding International Health Conference Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Finny Fitry Yani

Universitas Andalas Padang

Author-ID : 4165589

Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Procalcitonin for detecting community-acquired bacterial pneumonia Devi Gusmaiyanto; Finny Fitry Yani; Efrida Efrida; Rizanda Machmud
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Background Pneumonia is a major cause of morbidity andmortality in children under five years of age. Pneumonia can be ofbacterial or viral origin. It is difficult to distinguish between thesetwo agents based on clinical manifestations, as well as radiologicaland laboratory examinations. Furthermore, bacterial cultures taketime to incubate and positive results may only be found in 10-30%of bacterial pneumonia cases. Procalcitonin has been used as amarker to distinguish etiologies, as bacterial infections tend toincrease serum procalcitonin levels.Objective To determine the sensitivity, specificity, positivepredictive value and negative predictive value of procalcitoninin community-acquired bacterial pneumonia.Method This cross-sectional study was conducted in thePediatric Health Department of Dr. M. Djamil Hospital, Padang.Subjects were selected by consecutive sampling. Procalcitoninmeasurements and PCR screening were performed on bloodspecimens from 32 pneumonia patients and compared.Results Of the 32 subjects, most were boys (56.25%), under 5years of age (99%), and had poor nutritional status (68.75%).Using a cut-off point of 0.25 ng/mL, procalcitonin level hada sensitivity of 92%, specificity 50%, positive predictive valueÂ 88%, and negative predictive value 60% for diagnosing bacterialÂ pneumonia. Using a cut-off point of 0.5 ng/mL, procalcitonin levelÂ had a specificity of 46%, specificity 83%, positive predictive valueÂ 91%, and negative predictive value 25%.Conclusion A cut-off point of 0.25 ng/mL of procalcitonin levelÂ may be more useful to screen for bacterial pneumonia than a cutoffÂ point of 0.5 ng / mL. However, if the 0.25 ng/mL cut-off pointÂ is used, careful monitoring will be required for negative results,Â as up to 40% may actually have bacterial pneumonia. [PaediatrIndones. 2015;55:65-9.].

Bacterial pneumonia score to identify bacterial pneumonia Ied Imilda; Finny Fitry Yani; Didik Hariyanto; Darfioes Basir
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Background Pneumonia is caused by either bacterial or viraletiologies, with similar symptoms in children. The bacterialpneumonia score (BPS) is a clinical assessment comprised ofseveral investigations: age, assessment of axillary temperature,absolute neutrophil count, band neutrophil percentage, andinterpretation of radiological examination. The score will use todifferentiate the etiology of pneumonia.Objective To determine the sensitivity, specificity, positivepredictive value, and negative predictive value of BPS inidentifying bacterial pneumonia in children.Methods This diagnostic study was performed at Dr. M. DjamilHospital, Padang, West Sumatera where subjects were selected byconsecutive sampling. Fifty-seven patients were diagnosed withpneumonia. Three patients suffered from ventricular septal defects,8 patients refused to provide blood specimens and 3 patientsâ€™chest X-rays could not be interpreted, hence, 43 subjects wereincluded in the study. Chest X-rays were interpreted by a pediatricpulmonology consultant. Leukocyte and differential counts wereperformed by a clinical pathology consultant. Subjectsâ€™ BPS scoreswere compared to multiplex PCR examinations of blood specimens,as the gold standard.Result Of 43 subjects, 27 (62.79%) were male. Subjectsâ€™ mean age was 29.3 (SD 21.5) months. Twenty (46.51%) subjects had good nutritional status, 4 (9.31%) subjects had axillary temperature â‰¥39Â°C, and 22 (51.16%) subjects had absolute neutrophil counts â‰¥8.000/mm3. Bacterial pneumonia score (BPS) had 69% sensitivity, 60% specificity, 42% positive predictive value, and 81% negative predictive value.Conclusion In this study, BPS has low sensitivity and specificityfor identifying bacterial pneumonia.

Tuberculosis score chart signs and symptoms in children with positive tuberculin skin tests Finny Fitry Yani; Rizanda Machmoed; Marhefdison Marhefdison; Darfioes Basir
Paediatrica Indonesiana Vol 52 No 2 (2012): March 2012
Publisher : Indonesian Pediatric Society

Background The Indonesian Pediatrics Respirology WorkingGroup (IPRWG) developed the tuberculosis (TB) scorechart to assist in diagnosing TB in community health centers(Puskesmas).Objectives To document signs and symptoms of the IPRWG TBscore chart, to analyze various combinations of these signs andsymptoms, and to compare these combinations in children withTB to those without TB, based on a TB score chart.Methods We performed a cross-sectional study from July toOctober 2008, in Padang, Bukittinggi and Pasaman. We recruitedchildren with known positive tuberculin skin tests (TST) from a2006 tuberculin survey. Questionnaires on signs and symptoms(IPRWG TB score chart) were completed and chest radiographswere obtained for all children. Subjects fulfilling a total score ofsix or more were considered to have a diagnosis of TB.Results We diagnosed TB in 78/285 (27.3%) subjects. A scorevalue of3 for the category of household contact (HHC) positivesmears was added in 21/78 subjects. However, the highest risk forTB disease was found in those diagnosed with no clear history ofHHC (58.9%; OR 192, 95% CI 22 to 1679). The highest riskfactors for TB were suggestive chest X-ray (34.6%; OR 9.2, 95%CI 3.6 to 23 .4) and fever lasting > 2 weeks (17.9%; OR 8, 95%CI 2.2 to 29.1), respectively. Of 46 children with TB diagnosisbut without HHC, the combination of undernourishment, lymphnode enlargement and suggestive chest X-ray was highest (28.2%).Individual or dual combination signs and symptoms were alsofound in children without TB diagnosis.Conclusion Various combinations of signs and symptoms couldlead to fulfillment of scoring for TB diagnosis. [Paediatr lndones.2012;5 2: 78-85].

Relationship between serum ferritin and zinc levels in patients with major thalassemia Hervita Yeni; Finny Fitry Yani; Amirah Zatil Izzah; Gustina Lubis
Paediatrica Indonesiana Vol 59 No 3 (2019): May 2019
Publisher : Indonesian Pediatric Society

Background In thalassemia patients, reduced zinc absorption results from increased serum iron due to repeated blood transfusions, increased iron absorption due to ineffective erythropoiesis, and competitive inhibition between iron and zinc in binding to transferrin, a means of transporting both types of minerals in the blood. Few studies have been done to examine zinc levels in thalassemia patients and its relationship with ferritin. Objective To compare serum zinc in thalassemia patients and healthy controls and to assess for a possible correlation between serum ferritin and zinc in thalassemia patients. Methods This cross-sectional study in 68 subjects was done from October 2016 to August 2017. Serum ferritin measured by chemiluminescence immunoassay and serum zinc by inductively coupled plasma mass spectrometry (ICP-MS). Wilcoxon test was used to analyze for differences between serum zinc in thalassemia patients and controls. Spearmanâ€™s correlation test was used to analyze for a possible correlation between ferritin and serum zinc in thalassemia patients. Results There were 34 patients with thalassemia and 34 healthy control subjects. The median serum zinc was 119.34 Âµg/dL (IQR=71.27) in the thalassemia group and 120.08 Âµg/dL (IQR=26.28) in the control group (P=0.36). There was no significant correlation between serum ferritin and zinc in thalassemic children (r=-0.023; P=0.895). Conclusion There is no significant difference in serum zinc levels between thalassemic children and healthy controls. There is no significant correlation between serum ferritin and zinc in thalassemic children.

CONCORDANCE OF THE SCORING SYSTEM AND GENE-XPERT MTB/RIF TO DIAGNOSE CHILDHOOD TUBERCULOSIS IN PRIMARY HEALTH CARE Laura Zeffira; Finny Fitry Yani; Rizanda Machmud
Jurnal EduHealth Vol. 12 No. 02 (2022): Edition March, Jurnal EduHealth
Publisher : Sean Institute

The Scoring system developed by the Indonesian childhood tuberculosis working group is an alternative way to clinically diagnose TB in children especially in primary health care, however, bacteriological confirmation using gene-Xpert MTB/RIF is still highly recommended. To compare childhood TB scoring system performance and gene-Xpert MTB/RIF results among children suspected of tuberculosis in primary health care. This study was conducted on 47 children who went to the primary health care facility. The design of this study was a cross-sectional study with a conformity test (kappa). Samples that meet the inclusion criteria are recorded in the form of age, gender, weight, height, nutritional status, previous history of BCG vaccination, and physical examination, then the data is entered into the scoring system. Sputum is obtained by induction and then examined using gene-Xpert. The number of boys and girls suspected of having pulmonary TB is almost the same. About 72% of children experience malnutrition and a positive BCG score is found in more than half of the samples. There were 51.1% of children in contact with positive smear adult TB patients. Based on the scoring system obtained a TB diagnosis of 74.5% whereas based on gene-Xpert MTB/RIF examination only 4.3% of children confirm TB. There is no match between the two (conformity test with the kappa values of -0.01 and suitability 0.397). There is no compatibility in making a diagnosis of pediatric tuberculosis between the scoring system and gene-Xpert MTB/RIF at the primary health care facility.

Retropharyngeal abscess, submandibular abscess, and regio colli abscess with bronchopneumonia in a 2.5-month-old boy Irhamna Yusra; Finny Fitry Yani
Majalah Kedokteran Andalas Vol 42, No 3 (2019): Published in September 2019
Publisher : Faculty of Medicine, Universitas Andalas

Deep neck space infections (DNSIs) in pediatric require more intimate management because of their rapidly progressive nature. Delay in diagnosis and treatment may lead to life-threatening complications. Objective: To report DNSIs as one of emergency case in children. Early diagnosis and immediate management can decrease morbidity and mortality rate in children. Case: A case of a 2.5-month-old boy with chief complain breathlessness due to deep neck space infections and bronchopneumonia. Patient was getting better after surgical drainage. Conclusions: It most commonly occurs in children younger than four years of age having medical history of streptococcal pharyngitis, rarely as a complication of recent trauma, odontogenic infection or extension of vertebral osteomyelitis. Management often consists of antimicrobial therapy and surgical drainage. With the cooperation of ENT specialist and pediatrician/pediatric infectious disease specialist. Management in PICU is mandatory due to high risk of complications.

Intraventricular Hemorrhage in Children with COVID-19 Confirmed Utari Gustiany G; Rahmi Lestari; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 6 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i6.526

Background. The most common symptom of Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is respiratory symptoms. However, neurological symptoms in adult patients are increasingly being reported. In children, neurological symptoms of COVID-19 are still underreported. This case report was aimed to describe intraventricular hemorrhage in a child with Covid-19 infection. Case presentation. We report a case of a 15-year-old girl with intraventricular bleeding, which is one of the COVID-19 infection symptoms or a possible symptom of a multisystem inflammatory syndrome in children (MIS-C). Laboratory tests on the first day of treatment showed an increase in leukocytes and decreased lymphocytes. On the 6th day of treatment, the patient had worsening symptoms of consciousness and high fever. The results of laboratory examination showed a decrease in kidney function and an increase in D-dimer. Conclusion. Severe clinical manifestations of COVID-19 can be in the form of neurological manifestations, one of which is intraventricular hemorrhage.

The Association between 25-(OH)D Level and Metabolic Control Status in Children with Type 1 Diabetes Mellitus at Dr. M. Djamil General Hospital Padang Dini Anggini; Eka Agustia Rini; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 6 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i6.530

Background. Type 1 diabetes mellitus (T1DM) is an autoimmune disease causing the destruction of pancreatic beta cells. This is an incurable condition, but with good metabolic control, an optimal quality of life can be achieved. Glycated hemoglobin (HbA1C) is still considered a reliable parameter of metabolic control. Studies showed vitamin D has a role in controlling glycemic homeostasis in children with T1DM. Calcidiol or 25-(OH)D is the best parameter to determine the level of vitamin D in the blood. This study aimed to evaluate the association between 25-(OH)D with metabolic control status in T1DM children at Dr. M. Djamil General Hospital Padang. Methods. A cross-sectional study was conducted on 43 pediatric patients with T1DM from July 2019-January 2021. Serum levels of 25-(OH)D were measured by direct CLIA method and classified into deficiency (≤ 20 ng/mL) and insufficiency (21–30 ng/mL). The HbA1C levels were calculated using the HPLC method and classified into good (<7%), adequate (7-8%), and poor (>8%) control. The Chi-square test and ANOVA were used for data analysis. The P-value of < 0.05 was considered statistically significant. Results. The majority of respondents were girls (53.5%), with 90.7% having a good nutritional status. The mean age at diagnosis was 11.25±2.85 years, and had been known to suffer from T1DM for 2.95±1.74 years. All respondents had abnormal levels of 25-(OH)D (100%), i.e., insufficiency (28%), deficiency (72%), poor (65.1%) metabolic control, and 96.4% of respondents with poor metabolic control had a deficiency of 25-(OH)D. (P-value <0.001). Conclusion. T1DM patients who have poor metabolic control have very low levels of 25-(OH)D.

Successful Long-Term Monitoring of Children with Scrofuloderma, Malnutrition, and HIV Destri Linjani; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 8 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i8.550

Background: Scrofuloderma is a skin TB that occurs percontinuitatum from tissues underneath, such as lymph nodes, muscles, and bones. It often affects children and young adults. The incidence of TB disease is estimated to increase 20-fold in children with HIV infection. Poor nutrition can affect the mortality rate of children with HIV infection. This case report presents long-term monitoring of boys aged 1 year 5 months with scrofuloderma, malnutrition, and HIV infection. The case report aims to assist children and caregivers in undergoing treatment to prevent drug withdrawal and nutritional procedures and monitor the growth and development of children. Case presentation: A 1-year and 5-month-old boy with a complaint of ulcers on his right neck since 12 months ago. He also complained of diarrhea 12 months ago, accompanied by recurrent stomatitis and progressive weight loss since 3 months ago. He looked pale 1 month ago. Blood laboratory examination with hemoglobin 5.1 gr/dl, leukocytes 5280 / mm3, platelets 323,000 / mm3, hematocrit 20%, reactive anti-HIV test, CD4 examination with a value of 178 cells / L, negative tuberculin test, a chest x-ray showed infiltrate in both lung fields, and bajah examination of the nodules in the Colli dextra region, with the impression of granulomatous inflammation that can be caused by mycobacterial infection. Conclusion: Tuberculosis is the most common opportunistic infection found in children with HIV infection and increases the mortality rate. There is a relationship between nutritional status and the incidence of mortality in HIV/AIDS children, so it is necessary to monitor children for adherence to treatment, improve nutritional status and reduce morbidity and mortality rates.

ANALISA PELAKSANAAN INVESTIGASI KONTAK DAN PEMBERIAN TERAPI PENCEGAHAN TUBERKULOSIS PADA ANAK DI KOTA PARIAMAN TAHUN 2020 Muhammad Hendri; Finny Fitry Yani; Edison edison
HUMAN CARE JOURNAL Vol 6, No 2 (2021): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v6i2.1255

Tuberkulosis (TB) anak merupakan penyakit yang menjadi permasalahan kesehatan baik ditingkat Global, Nasional, sampai ketingkat kabupaten/kota. Dampak tidak dilakukannya penemuan kasus TB pada anak terutama balita yaitu beresiko tertular kuman TB yang menyebabkan balita menjadi sakit TB. Jika tidak diobati maka balita akan mengalami TB berat hingga terjadinya kematian. Masih rendahnya penemuan kasus TB pada balita disebabkan penemuan kasus masih bersifat pasif, yaitu menunggu di Puskesmas. Kebijakan Kementerian Kesehatan RI dalam penemuan kasus yaitu menggunakan pelaksanaan investigasi kontak TB. Penemuan kasus TB anak di Kota Pariaman 3 (tiga) tahun terakhir mengalami penurunan dan pemberian terapi pencegahan pada balita di Kota Pariaman belum pernah dilaksanakan dalam 3 (tiga) tahun tarakhir ini. Tujuan penelitian ini untuk melihat gambaran pelaksanaan investigasi kontak dan pemberian terapi pencegahan di Kota Pariaman Tahun 2020. Metode yang dipakai pada penelitian ini yaitu menggunakan mix methode. Hasil penelitian pelaksanaan investigasi kontak TB belum berjalan optimal yang disebabkan karena masih lemahnya pernecanaan program TB sehingga tidak adanya anggaran khusus dalam pelaksanaan investigasi kontak. Selain perencanaan yang lemah, penyebab belum optimalnya pelaksanaan investigasi kontak adalah masih kurangnya koordinasi serta monitoring dan evaluasi baik dari tingkat Dinas Kesehatan maupun dari pihak Puskesmas.Kata kunci: TB balita, investigasi kontak TB, Terapi Pencegahan TB

Co-Authors Abi Andayu Adang Bachtiar Adefri Wahyudi Afdal Afdal Afdal Ahmad Junaidi Ahmad Kurniawan Akbar Aidil Rahman Novesar Alfi Maido Alius Amelin, Fitrisia Amirah Zatil Izzah Andani Eka Putra Ariescha, Putri Ayu Yessy Arni Amir Arwin AP Akib Asrawati Asrawati Aumas Pabuti Aumas Pabuti Bachti Alisjahbana Bambang Supriyatno Br Ginting Munthe, Novita Chicy WIdya Morfi Chika Aulia Husna Darfioes Basir Darfioes Basir Darfioes Basir Darfioes Basir Darfioes Basir Darfious Basir Darmawan B. Setyanto Dasman, Hardisman Denas Symond Desmawati Destri Linjani Devi Gusmaiyanto Devita, Retno Dhyna Lidya Lestari Diana Nur Asrini Didik Hariyanto Didik Hariyanto Didik Hariyanto Dini Anggini Diska Yulia Trisiana Diska Yulia Trisiana Dita Maharani Dwiana Ocviyanti Dwiana Ocviyanti Dwihardiani, Bintari Dya Mulya Lestari Edison Edison Efrida Efrida Efrida Eka Agustia Rini Elsesmita Elsesmita Emeraldy Chatra Erkadius Erkadius Erli Meichory Viorika Eryati Darwin Fauzar Fauzar Felisia . Firman Arbi Gustina Lubis Gustina Lubis Gustina Lubis Hafifatul A Rahmy Hafni Bachtiar Hanifa Hanif Hardisman Dasman Harun Harnavi Helmizar Hervita Yeni Hirowati Ali, Hirowati Husna Yetti Husna Yetti Ied Imilda Ikhsan Marzony Ilmiawati Ilmiawati, Ilmiawati Imil Irsal Imran Indra Ihsan Indrapriyatna, Ahmad Syafruddin Indri Permata Rani Irhamna Yusra Irvan Medison Irvan Medison Irvan Medison Iskandar Fitri, Iskandar Joserizal Serudji Koesoemadinata, Raspati Cundarani Laura Zeffira Lita Farlina Liza Fitria Lydia Aswati, Lydia Machdawaty Masri Masri Marhefdison Marhefdison Muhammad Hendri Nastiti Kaswandani Nelwati Nelwati Nelwati, Nelwati Nia Kurniati Nice Rachmawati Nina Dwi Putri Nisa Haska Maulina Novi Violona Edwar Novita Br Ginting Munthe Nur Afrainin Syah Nur Indrawaty Lipoeto Nurul Noviarisa Osharinanda Monita Rahmi Lestari Rapida Saragih Revi Riliani Riana Youri Ricco Azali Riki Alkamdani Rima Semiarty Rina Triasih Rinang Mariko Rizanda Machmoed Rizanda Machmoed Rizanda Machmud Rizki Meizikri Roni Eka Sahputra Roza Erisma Roza Kurniati Russilawati, Russilawati Sahputra, Roni Eka Sari, Maharani Permata Shinta Ayudhia Stephen M. Graham, Stephen M. Susmiati Susmiati Syahredi SA Trisasi Lestari, Trisasi Triyanto Triyanto Utari Gustiany G Viorika, Erli Meichory Yuhandri Yuhandri, Yuhandri Yuniar Lestari Yuniar Lestari Yusrawati Yusrawati Yusri Dianne Jurnalis

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