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All Journal Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Sari Pediatri Paediatrica Indonesiana Majalah Kedokteran Andalas Human Care Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Jurnal Ners Indonesian Journal of Electrical Engineering and Computer Science Science Midwifery Indonesian Journal of Global Health research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal EduHealth Jurnal Ilmu Kesehatan Indonesia (JIKSI) Eduvest - Journal of Universal Studies Indonesian Journal of Advanced Research (IJAR) JOURNAL OF Mother and Child Health Concerns Jurnal Riset Ilmiah Proceeding International Health Conference Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal) Frontiers on Healthcare Research Jurnal Ilmu Kesehatan Masyarakat

Finny Fitry Yani

Universitas Andalas

Author-ID : 4165589

Aerospace Engineering Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Procalcitonin for detecting community-acquired bacterial pneumonia Devi Gusmaiyanto; Finny Fitry Yani; Efrida Efrida; Rizanda Machmud
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Background Pneumonia is a major cause of morbidity andmortality in children under five years of age. Pneumonia can be ofbacterial or viral origin. It is difficult to distinguish between thesetwo agents based on clinical manifestations, as well as radiologicaland laboratory examinations. Furthermore, bacterial cultures taketime to incubate and positive results may only be found in 10-30%of bacterial pneumonia cases. Procalcitonin has been used as amarker to distinguish etiologies, as bacterial infections tend toincrease serum procalcitonin levels.Objective To determine the sensitivity, specificity, positivepredictive value and negative predictive value of procalcitoninin community-acquired bacterial pneumonia.Method This cross-sectional study was conducted in thePediatric Health Department of Dr. M. Djamil Hospital, Padang.Subjects were selected by consecutive sampling. Procalcitoninmeasurements and PCR screening were performed on bloodspecimens from 32 pneumonia patients and compared.Results Of the 32 subjects, most were boys (56.25%), under 5years of age (99%), and had poor nutritional status (68.75%).Using a cut-off point of 0.25 ng/mL, procalcitonin level hada sensitivity of 92%, specificity 50%, positive predictive valueÂ 88%, and negative predictive value 60% for diagnosing bacterialÂ pneumonia. Using a cut-off point of 0.5 ng/mL, procalcitonin levelÂ had a specificity of 46%, specificity 83%, positive predictive valueÂ 91%, and negative predictive value 25%.Conclusion A cut-off point of 0.25 ng/mL of procalcitonin levelÂ may be more useful to screen for bacterial pneumonia than a cutoffÂ point of 0.5 ng / mL. However, if the 0.25 ng/mL cut-off pointÂ is used, careful monitoring will be required for negative results,Â as up to 40% may actually have bacterial pneumonia. [PaediatrIndones. 2015;55:65-9.].

Bacterial pneumonia score to identify bacterial pneumonia Ied Imilda; Finny Fitry Yani; Didik Hariyanto; Darfioes Basir
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Background Pneumonia is caused by either bacterial or viraletiologies, with similar symptoms in children. The bacterialpneumonia score (BPS) is a clinical assessment comprised ofseveral investigations: age, assessment of axillary temperature,absolute neutrophil count, band neutrophil percentage, andinterpretation of radiological examination. The score will use todifferentiate the etiology of pneumonia.Objective To determine the sensitivity, specificity, positivepredictive value, and negative predictive value of BPS inidentifying bacterial pneumonia in children.Methods This diagnostic study was performed at Dr. M. DjamilHospital, Padang, West Sumatera where subjects were selected byconsecutive sampling. Fifty-seven patients were diagnosed withpneumonia. Three patients suffered from ventricular septal defects,8 patients refused to provide blood specimens and 3 patientsâ€™chest X-rays could not be interpreted, hence, 43 subjects wereincluded in the study. Chest X-rays were interpreted by a pediatricpulmonology consultant. Leukocyte and differential counts wereperformed by a clinical pathology consultant. Subjectsâ€™ BPS scoreswere compared to multiplex PCR examinations of blood specimens,as the gold standard.Result Of 43 subjects, 27 (62.79%) were male. Subjectsâ€™ mean age was 29.3 (SD 21.5) months. Twenty (46.51%) subjects had good nutritional status, 4 (9.31%) subjects had axillary temperature â‰¥39Â°C, and 22 (51.16%) subjects had absolute neutrophil counts â‰¥8.000/mm3. Bacterial pneumonia score (BPS) had 69% sensitivity, 60% specificity, 42% positive predictive value, and 81% negative predictive value.Conclusion In this study, BPS has low sensitivity and specificityfor identifying bacterial pneumonia.

Tuberculosis score chart signs and symptoms in children with positive tuberculin skin tests Finny Fitry Yani; Rizanda Machmoed; Marhefdison Marhefdison; Darfioes Basir
Paediatrica Indonesiana Vol 52 No 2 (2012): March 2012
Publisher : Indonesian Pediatric Society

Background The Indonesian Pediatrics Respirology WorkingGroup (IPRWG) developed the tuberculosis (TB) scorechart to assist in diagnosing TB in community health centers(Puskesmas).Objectives To document signs and symptoms of the IPRWG TBscore chart, to analyze various combinations of these signs andsymptoms, and to compare these combinations in children withTB to those without TB, based on a TB score chart.Methods We performed a cross-sectional study from July toOctober 2008, in Padang, Bukittinggi and Pasaman. We recruitedchildren with known positive tuberculin skin tests (TST) from a2006 tuberculin survey. Questionnaires on signs and symptoms(IPRWG TB score chart) were completed and chest radiographswere obtained for all children. Subjects fulfilling a total score ofsix or more were considered to have a diagnosis of TB.Results We diagnosed TB in 78/285 (27.3%) subjects. A scorevalue of3 for the category of household contact (HHC) positivesmears was added in 21/78 subjects. However, the highest risk forTB disease was found in those diagnosed with no clear history ofHHC (58.9%; OR 192, 95% CI 22 to 1679). The highest riskfactors for TB were suggestive chest X-ray (34.6%; OR 9.2, 95%CI 3.6 to 23 .4) and fever lasting > 2 weeks (17.9%; OR 8, 95%CI 2.2 to 29.1), respectively. Of 46 children with TB diagnosisbut without HHC, the combination of undernourishment, lymphnode enlargement and suggestive chest X-ray was highest (28.2%).Individual or dual combination signs and symptoms were alsofound in children without TB diagnosis.Conclusion Various combinations of signs and symptoms couldlead to fulfillment of scoring for TB diagnosis. [Paediatr lndones.2012;5 2: 78-85].

Relationship between serum ferritin and zinc levels in patients with major thalassemia Hervita Yeni; Finny Fitry Yani; Amirah Zatil Izzah; Gustina Lubis
Paediatrica Indonesiana Vol 59 No 3 (2019): May 2019
Publisher : Indonesian Pediatric Society

Background In thalassemia patients, reduced zinc absorption results from increased serum iron due to repeated blood transfusions, increased iron absorption due to ineffective erythropoiesis, and competitive inhibition between iron and zinc in binding to transferrin, a means of transporting both types of minerals in the blood. Few studies have been done to examine zinc levels in thalassemia patients and its relationship with ferritin. Objective To compare serum zinc in thalassemia patients and healthy controls and to assess for a possible correlation between serum ferritin and zinc in thalassemia patients. Methods This cross-sectional study in 68 subjects was done from October 2016 to August 2017. Serum ferritin measured by chemiluminescence immunoassay and serum zinc by inductively coupled plasma mass spectrometry (ICP-MS). Wilcoxon test was used to analyze for differences between serum zinc in thalassemia patients and controls. Spearmanâ€™s correlation test was used to analyze for a possible correlation between ferritin and serum zinc in thalassemia patients. Results There were 34 patients with thalassemia and 34 healthy control subjects. The median serum zinc was 119.34 Âµg/dL (IQR=71.27) in the thalassemia group and 120.08 Âµg/dL (IQR=26.28) in the control group (P=0.36). There was no significant correlation between serum ferritin and zinc in thalassemic children (r=-0.023; P=0.895). Conclusion There is no significant difference in serum zinc levels between thalassemic children and healthy controls. There is no significant correlation between serum ferritin and zinc in thalassemic children.

Retropharyngeal abscess, submandibular abscess, and regio colli abscess with bronchopneumonia in a 2.5-month-old boy Irhamna Yusra; Finny Fitry Yani
Majalah Kedokteran Andalas Vol 42, No 3 (2019): Published in September 2019
Publisher : Faculty of Medicine, Universitas Andalas

Deep neck space infections (DNSIs) in pediatric require more intimate management because of their rapidly progressive nature. Delay in diagnosis and treatment may lead to life-threatening complications. Objective: To report DNSIs as one of emergency case in children. Early diagnosis and immediate management can decrease morbidity and mortality rate in children. Case: A case of a 2.5-month-old boy with chief complain breathlessness due to deep neck space infections and bronchopneumonia. Patient was getting better after surgical drainage. Conclusions: It most commonly occurs in children younger than four years of age having medical history of streptococcal pharyngitis, rarely as a complication of recent trauma, odontogenic infection or extension of vertebral osteomyelitis. Management often consists of antimicrobial therapy and surgical drainage. With the cooperation of ENT specialist and pediatrician/pediatric infectious disease specialist. Management in PICU is mandatory due to high risk of complications.

ANALISA PELAKSANAAN INVESTIGASI KONTAK DAN PEMBERIAN TERAPI PENCEGAHAN TUBERKULOSIS PADA ANAK DI KOTA PARIAMAN TAHUN 2020 Muhammad Hendri; Finny Fitry Yani; Edison edison
HUMAN CARE JOURNAL Vol 6, No 2 (2021): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v6i2.1255

Tuberkulosis (TB) anak merupakan penyakit yang menjadi permasalahan kesehatan baik ditingkat Global, Nasional, sampai ketingkat kabupaten/kota. Dampak tidak dilakukannya penemuan kasus TB pada anak terutama balita yaitu beresiko tertular kuman TB yang menyebabkan balita menjadi sakit TB. Jika tidak diobati maka balita akan mengalami TB berat hingga terjadinya kematian. Masih rendahnya penemuan kasus TB pada balita disebabkan penemuan kasus masih bersifat pasif, yaitu menunggu di Puskesmas. Kebijakan Kementerian Kesehatan RI dalam penemuan kasus yaitu menggunakan pelaksanaan investigasi kontak TB. Penemuan kasus TB anak di Kota Pariaman 3 (tiga) tahun terakhir mengalami penurunan dan pemberian terapi pencegahan pada balita di Kota Pariaman belum pernah dilaksanakan dalam 3 (tiga) tahun tarakhir ini. Tujuan penelitian ini untuk melihat gambaran pelaksanaan investigasi kontak dan pemberian terapi pencegahan di Kota Pariaman Tahun 2020. Metode yang dipakai pada penelitian ini yaitu menggunakan mix methode. Hasil penelitian pelaksanaan investigasi kontak TB belum berjalan optimal yang disebabkan karena masih lemahnya pernecanaan program TB sehingga tidak adanya anggaran khusus dalam pelaksanaan investigasi kontak. Selain perencanaan yang lemah, penyebab belum optimalnya pelaksanaan investigasi kontak adalah masih kurangnya koordinasi serta monitoring dan evaluasi baik dari tingkat Dinas Kesehatan maupun dari pihak Puskesmas.Kata kunci: TB balita, investigasi kontak TB, Terapi Pencegahan TB

Status Vitamin D pada Anak dengan Leukemia Akut Shinta Ayudhia; Amirah Zatil Izzah; Firman Arbi; Finny Fitry Yani
Sari Pediatri Vol 24, No 1 (2022)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp24.1.2022.51-5

Latar belakang. Vitamin D adalah kelompok prohormon yang berperan dalam pencegahan dan pertumbuhan sel kanker sebagai antiproliferatif, pro apoptosis dan anti inflamasi. Hal ini disebabkan karena reseptor vitamin D juga terdapat pada sel hematopoesis normal dan abnormal. Namun, penelitian tentang vitamin D pada anak dengan leukemia masih sedikit. Dari beberapa penelitian yang telah ada menunjukkan kadar vitamin D pada pasien leukemia berada pada level defisiensi dan insufisiensi.Tujuan. Mengetahui status vitamin D pada pasien leukemia akut di Rumah Sakit Umum Pusat M. Djamil, Padang.Metode. Penelitian potong lintang dilakukan pada 53 pasien anak yang baru terdiagnosis leukemia akut dari bulan Mei 2018 hingga Mei 2019. Dilakukan pemeriksaan kadar vitamin D di laboratorium dan pengumpulan data karakteristik pasien.Hasil. Didapatkan 30 (56,6%) pasien berjenis kelamin laki-laki, rentang umur paling banyak usia 1-10 tahun. Status gizi kurang terdapat pada 47 (88,7%) pasien. Diagnosis leukemia limfoblastik akut didapatkan 47 (88,7%) pasien. Gejala klinis terbanyak adalah demam (96,2%), pucat (96,2%), hepatomegali (92,5%). Pasien mendapatkan paparan matahari > 30 menit sebanyak 86,8%. Rerata kadar vitamin D pada pasien leukemia akut adalah 24,01±7,91 ng/ml. Status vitamin D pada pasien leukemia akut 50,9% berada pada rentang insufisiensi.Kesimpulan. Status vitamin D pada pasien leukemia akut di RSUP M. Djamil berada pada rentang insufisiensi.

Gene Polymorphisms Vitamin D Receptor Against Dengue Infection In Children Ahmad Kurniawan Akbar; Nur Indrawaty Lipoeto; Arni Amir; Finny Fitry Yani
Majalah Kedokteran Andalas Vol 45, No 3 (2022): Online July 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v45.i3.p417-422.2022

BACKGROUND: Dengue infection is a vector-born disease associated with endemic areas in the tropics and subtropics. Genetic factors that play a role such as mutations and polymorphisms that influence a person's susceptibility to dengue fever. AIM: This study aims to determine gene polymorphisms of vitamin D against dengue infection in children. MATERIAL AND METHODS: This study was an observational study with a cross-sectional design, where the dependent and independent variables were examined at the same time in pediatric patients who were hospitalized with clinical symptoms of dengue infection at Raden Mattaher Hospital Jambi and Baiturrahim Jambi Hospital who met the inclusion criteria with positive anti-dengue IgM. and or positive anti-dengue IgG in children aged less than two years to eighteen years. RESULT: The results showed that the relationship between patients who have polymorphisms in one of the vitamin D receptor genes will experience heavier dengue infection than those who do not have polymorphisms in the vitamin D receptor gene and this difference is statistically significan (p= 0.005). CONCLUSION: This study concluded that there was a relationship between vitamin D receptor gene polymorphisms and the degree of dengue virus infection. Keywords: Dengue infection in children, Vitamin D receptor gene polymorphisms, vitamin D level

Kajian Terkini CoronaVirus Disease 2019 (COVID-19) Chicy Widya Morfi; Ahmad Junaidi; Elsesmita Elsesmita; Diana Nur Asrini; Dya Mulya Lestari; Irvan Medison; Russilawati Russilawati; Fauzar Fauzar; Roza Kurniati; Finny Fitry Yani
Jurnal Ilmu Kesehatan Indonesia Vol 1 No 1 (2020): Maret 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

The COVID-19 outbreak in Wuhan, Hubei Province, China, caused by a newly known coronavirus strain, SARS-CoV-2, up to March 3th, 2020, has caused 90.870 confirmed cases to be reported from 72 countries (including Indonesia) with 3.112 deaths (CFR 3,4%). Upper airway swab and lower airway aspirate specimens from suspected patients are required for examination by the RT-PCR microbiological method for establishing COVID-19. There are no specific antivirals for the management of COVID-19. On January, 30th, 2020 WHO has established Covid-19 as the Public Health Emergency of International Concern (PHEIC), but the increase in the number of cases is fast enough so that on March,11th 2020, WHO has established Covid-19 as a pandemic.

Neonatus dari Ibu Tuberkulosis Aktif Revi Riliani; Finny Fitry Yani
Jurnal Ilmu Kesehatan Indonesia Vol 1 No 1 (2020): Maret 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

TB merupakan salah satu penyakit menular terbanyak di dunia dan mengalami perubahan dalam epidemiologi dimana terjadi peningkatan proporsi wanita usia subur yang tertular TB dan selanjutnya berkemungkinan akan berdampak pada kejadian TB perinatal. Diperkirakan insiden transmisi vertikal TB dari ibu ke bayi sebesar 16%, dengan angka kematian yang tinggi yaitu 50-60%. Kesulitan dalam diagnosis berkontribusi pada tingginya angka kematian ini. Indeks kecurigaan yang tinggi disertai penelusuran infeksi dapat menurunkan angka kematian akibat TB kongenital, serta pemberian pengobatan profilaksis yang optimal dapat mencegah kejadian TB perinatal pada bayi yang terpapar dengan penderita. Penulisan kasus ini bertujuan untuk melihat luaran pada bayi yang terpapar tuberkulosis dan mendapatkan pengobatan profilaksis. Penelusuran literatur dilakukan oleh dua orang melalui PubMed dan DOAJ untuk mencari penelitian yang relevan. Kata teks digunakan dalam pencarian studi. Dari penelusuran didapatkan empat studi memenuhi kriteria eligibilitas. Dari keempat studi, pada dua studi ditemukan hanya satu subjek yang mendapat pengobatan profilaksis yang berkembang menjadi infeksi tuberkulosis. Dengan demikian dapat disimpulkan bahwa pemberian profilaksis pada bayi yang terpapar tuberkulosis berpengaruh pada luaran dan efektif menjegah progresivitas penyakit.

Co-Authors Abi Andayu Adang Bachtiar Adang Bachtiar Adefri Wahyudi Afdal Afdal Afdal Afdal, Afdal Ahmad Junaidi Ahmad Kurniawan Akbar Aidil Rahman Novesar Al Hafiz Alfi Maido Alius Alkamdani, Riki Amelin, Fitrisia Amir, Arni Amirah Zatil Izzah Andani Eka Putra Anisya Selvia Ariescha, Putri Ayu Yessy Arni Amir Arwin AP Akib Asrawati Asrawati Aumas Pabuti Aumas Pabuti Bachti Alisjahbana Bambang Supriyatno Beni Indra, Beni Br Ginting Munthe, Novita Chicy WIdya Morfi Chika Aulia Husna Dachriyanus Darfioes Basir Darfioes Basir Darfioes Basir Darfioes Basir Darfioes Basir Darfious Basir Darmawan B. Setyanto Dasman, Hardisman Delmi Sulastri Denas Symond Desmawati Desmawati Desmawati Destri Linjani Devi Gusmaiyanto Dhyna Lidya Lestari Diana Nur Asrini Didi Yunaspi Didik Hariyanto Didik Hariyanto Dini Anggini Diska Yulia Trisiana Diska Yulia Trisiana Dita Maharani Dwiana Ocviyanti Dwihardiani, Bintari Dya Mulya Lestari Edison Edison Efrida Efrida Eka Agustia Rini Elmatris Sy Elsesmita Elsesmita Emeraldy Chatra Erkadius Erkadius Erli Meichory Viorika Eryati Darwin Fachry Abda El Rahman Fauzan Azima Fauzar Fauzar Felisia . Firdawati Firdawati Firman Arbi Gustina Lubis Gustina Lubis Hafifatul A Rahmy Hafni Bachtiar Hanifa Hanif Hardisman Dasman Harun Harnavi Helmizar Hervita Yeni Hirowati Ali, Hirowati Humaira, Hamdini Husna Yetti Ied Imilda Ihsan, Indra Ikhsan Marzony Ilmiawati Ilmiawati, Ilmiawati Imil Irsal Imran Indra Ihsan Indrapriyatna, Ahmad Syafruddin Indri Permata Rani Irhamna Yusra Irvan Medison Irvan Medison Irvan Medison Iskandar Fitri, Iskandar Joserizal Serudji Koesoemadinata, Raspati C. Lestari, Rahmi Lita Farlina Liza Fitria Liza Fitria, Liza Lydia Aswati, Lydia Machdawaty Masri Masri Maharani Permata Sari Marhefdison Marhefdison Masrul Djalal Miko, Alfan Muhammad Hendri Mukhti, Karina Astarini Nastiti Kaswandani Nelwati Nelwati Nelwati, Nelwati Nia Kurniati Nice Rachmawati Nice Rachmawati Masnadi Nina Dwi Putri Nisa Haska Maulina Novi Violona Edwar Novialdi . Novita Br Ginting Munthe Novita Br Ginting Munthe Nur Afrainin Syah Nur Indrawaty Lipoeto Nurul Noviarisa Osharinanda Monita Rahmi Lestari Rahmi, Yannisa Mutiara Rapida Saragih Ratno Widoyo, Ratno Resti Ayu Safitri Retno Devita Revi Riliani Ricco Azali Rima Semiarty Rina Triasih Rinang Mariko Rinang Mariko Rinang Mariko, Rinang Rizanda Machmoed Rizanda Machmoed Rizanda Machmud Rizanda Machmud Rizki Meizikri Roza Erisma Roza Kurniati Russilawati, Russilawati Sahputra, Roni Eka Shinta Ayudhia Stephen M. Graham, Stephen M. Susmiati Susmiati Syahredi SA Trisasi Lestari, Trisasi Triyanto Triyanto Utari Gustiany G Viorika, Erli Meichory Youri, Riana Yuhandri Yuhandri, Yuhandri Yuniar Lestari Yuniar Lestari Yusrawati Yusrawati Yusri Dianne Jurnalis Yusri Dianne Jurnalis Zeffira, Laura Zelly Dia Rofinda

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