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Characteristics of Nutrients and Microbiological Dadih Puding as Food Supplementation for Children with Sars-Cov-2 Infection Helmizar Helmizar; Hafifatul A Rahmy; Susmiati Susmiati; Asrawati Asrawati; Nice Rachmawati; Finny Fitry Yani
Jurnal Kesehatan Masyarakat Andalas Vol 16 No 1 (2022): Jurnal Kesehatan Masyarakat Andalas
Publisher : Faculty of Public Health, Andalas University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24893/jkma.v16i1.1041

The Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) that cause COVID-19 global pandemic is a devastating disease causing thousands of victims every day. Therefore, there must be a certain effort to reduce the risk of the disease progress, including improvement of individual immune system like the probiotic supplementation. Meanwhile, dadih is a dairy product obtained from fermented buffalo milk contains various nutrients for human body, especially probiotics that beneficial for reducing the risk of COVID-19 infection in children. The aim of the study was to determine the nutritional and microbiological content of dadih pudding as additional supplementation in children confirmed positive for COVID-19. The study design was True Experiment using Completely Randomized Design (CRD). It consisted of four formulas. They were F0 as the standard formula, then F1, F2, and F3 as the treatment formula by adding dadih 50, 60, 70, and 80 grams, respectively. This study was initiated with the analysis of biochemical nutritional valueÂ at a laboratory in Padang Research Center and Industry Standardization. Besides, it also determined the number of total Acid Lactic Bacterial quantification which was analyzed at microbiology laboratory, Agricultured Technology Faculty, UniversitasÂ Andalas. Nutrients and lactic acid bacteria in dadih pudding are potential as food supplementation, especially for children with COVID-19 infection. It is strongly recommended to give probiotic dadih to children in order to counter oxidative stress and inflammation, and the setting of COVID-19.Â

Calcitriol levels and the stage of chronic kidney disease in children Diska Yulia Trisiana; Finny Fitry Yani; Fitrisia Amelin; Aumas Pabuti
Paediatrica Indonesiana Vol 62 No 5 (2022): September 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.5.2022.318-23

Background Kidney damage in chronic kidney disease (CKD) disrupts the 1?-hydroxylase enzyme, preventing the conversion of vitamin D into the active form of calcitriol. To our knowledge, no previous studies have assessed calcitriol levels in children with CKD. Decreased vitamin D levels may occur at an early stage of the disease, so it is important to evaluate calcitriol levels in children with early stage CKD. Objective To assess calcitriol levels in children with CKD according to disease stage and other characteristics. Methods This cross-sectional study was conducted on 43 pediatric CKD patients at Dr. M Djamil Hospital, Padang, Indonesia. We recorded patient characteristics and performed laboratory tests, including routine hematology, blood urea nitrogen (BUN), creatinine, uric acid, electrolytes, calcium, and calcitriol levels. Based on estimated glomerular filtration rate (GFR), patients were grouped into either early-stage (stages I and II), or advanced-stage (stages III to V) CKD. Univariate and multivariate analyses were conducted to determine the association between calcitriol levels with disease stage and other characteristics. Results The overall mean calcitriol level of our subjects was 108.77 (SD 10.79) pmol/L. Mean levels at each CKD stage from I to V were 164.28 (SD 160.90), 94.14 (SD 50.63), 72.16 (SD 13.18), 62.92 (SD 4.87), and 67.51 (SD 4.87) pmol/L, respectively. Calcitriol levels did not differ significantly by CKD stage (P=0.114) when each stage from I to V was considered separately. There was no significant difference in calcitriol levels by growth characteristics (P=0.944), etiology (P=0.311), or anemic status (P=0.104). However, low calcitriol levels were found in all subjects with advanced stage CKD, compared to 63.6% subjects with early stage CKD (P=0.004). Mean calcitriol levels were significantly lower in CKD stage IV (P=0.049) and stage V (P=0.027) compared to stage I. Conclusions The decrease in calcitriol level occurs at an early stage in CKD. Calcitriol levels are significantly lower in advanced stage than in early stage CKD.

Overview of Risk Factors for Toddlers with Congenital Heart Disease Suffering from Pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia Ricco Azali; Didik Hariyanto; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.717

Background: Congenital heart disease (CHD) includes structural and non-structural abnormalities that arise from birth. Disorders of the circulatory system can also affect the respiratory system, causing symptoms and disturbances that similar to primary respiratory disease. This study aimed to describe the risk factors for toddlers with congenital heart disease who suffer from pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: Descriptive observational study using secondary data. A total of 58 research subjects participated in the study. The research subjects met the inclusion criteria in the form of patients who had been diagnosed with congenital heart disease, aged 29 days – 60 months, and were treated at Dr. M. Djamil General Hospital, Padang, Indonesia. Data analysis was performed using SPSS software univariately. Results: The majority of patients with various age levels have a cured outcome. The majority of subjects with medium and high parental education had a greater recovery percentage than subjects with low parental education. Subjects with medium and high socioeconomic status had a greater percentage of recovery outcomes than subjects with low socioeconomic status. The majority of subjects with normal nutritional status and normal birth weight had a higher percentage of recovered outcomes than those who died. The history of DPT immunization and the type of congenital heart disease did not show a large percentage difference between patients who recovered and died. History of measles immunization and leukocytosis showed a greater percentage of patients with cured outcomes than death outcomes. Conclusion: CHD patients with pneumonia are under 1 year old, male, come from families with low-medium socioeconomic status, low-medium educational level, and malnutrition status have worse patient outcomes.

Overview of Risk Factors for Toddlers with Congenital Heart Disease Suffering from Pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia Ricco Azali; Didik Hariyanto; Finny Fitry Yani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 17 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i17.717

Background: Congenital heart disease (CHD) includes structural and non-structural abnormalities that arise from birth. Disorders of the circulatory system can also affect the respiratory system, causing symptoms and disturbances that similar to primary respiratory disease. This study aimed to describe the risk factors for toddlers with congenital heart disease who suffer from pneumonia at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: Descriptive observational study using secondary data. A total of 58 research subjects participated in the study. The research subjects met the inclusion criteria in the form of patients who had been diagnosed with congenital heart disease, aged 29 days – 60 months, and were treated at Dr. M. Djamil General Hospital, Padang, Indonesia. Data analysis was performed using SPSS software univariately. Results: The majority of patients with various age levels have a cured outcome. The majority of subjects with medium and high parental education had a greater recovery percentage than subjects with low parental education. Subjects with medium and high socioeconomic status had a greater percentage of recovery outcomes than subjects with low socioeconomic status. The majority of subjects with normal nutritional status and normal birth weight had a higher percentage of recovered outcomes than those who died. The history of DPT immunization and the type of congenital heart disease did not show a large percentage difference between patients who recovered and died. History of measles immunization and leukocytosis showed a greater percentage of patients with cured outcomes than death outcomes. Conclusion: CHD patients with pneumonia are under 1 year old, male, come from families with low-medium socioeconomic status, low-medium educational level, and malnutrition status have worse patient outcomes.

Delayed Bochdalek Diaphragmatic Hernia Appearance and Coincidence with Pneumonia in One-Year-Old Baby: A Case Report Imil Irsal Imran; Finny Fitry Yani; Riki Alkamdani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 2 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i2.783

Background: Congenital diaphragmatic hernia (CDH) is a developmental defect in the diaphragm leading to protrusion of abdominal contents into the thoracic cavity. The incidence rates showed that this disease happened to one in 2,200-3,000 births. This study aimed to describe a case of delayed Boschdalek diaphragmatic hernia and coincidence with pneumonia in a one-year-old baby. Case Presentation: A 12-month-old girl came to the emergency room of Dr. M. Djamil General Hospital with a chief complaint of breathlessness for 2 days before admission to the hospital. She had difficulty gaining weight, only about 200 grams per month. The symptoms are breathlessness, cyanosis, asymmetry of lung sounds, change in the position of the heart sound, and scaphoid abdomen. The chest X-ray showed the opacity loops, which are fluid-filled, suggestive left diaphragmatic hernia. Conclusion: Pneumonia-like symptoms and signs could be an initial or coincidence with delayed presentation of Bochdalek hernia diaphragmatic.

Delayed Bochdalek Diaphragmatic Hernia Appearance and Coincidence with Pneumonia in One-Year-Old Baby: A Case Report Imil Irsal Imran; Finny Fitry Yani; Riki Alkamdani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 7 No. 2 (2023): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v7i2.783

Background: Congenital diaphragmatic hernia (CDH) is a developmental defect in the diaphragm leading to protrusion of abdominal contents into the thoracic cavity. The incidence rates showed that this disease happened to one in 2,200-3,000 births. This study aimed to describe a case of delayed Boschdalek diaphragmatic hernia and coincidence with pneumonia in a one-year-old baby. Case Presentation: A 12-month-old girl came to the emergency room of Dr. M. Djamil General Hospital with a chief complaint of breathlessness for 2 days before admission to the hospital. She had difficulty gaining weight, only about 200 grams per month. The symptoms are breathlessness, cyanosis, asymmetry of lung sounds, change in the position of the heart sound, and scaphoid abdomen. The chest X-ray showed the opacity loops, which are fluid-filled, suggestive left diaphragmatic hernia. Conclusion: Pneumonia-like symptoms and signs could be an initial or coincidence with delayed presentation of Bochdalek hernia diaphragmatic.

Pengaruh Pemberian Kolostrum Susu Sapi Terhadap Durasi Diare Akut Dehidrasi Ringan Sedang dan Kadar Sekretori Imunoglobulin A pada Anak Alfi Maido Alius; Yusri Dianne Jurnalis; Finny Fitry Yani
Sari Pediatri Vol 24, No 6 (2023)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp24.6.2023.388-94

Latar belakang. Kolostrum susu sapi atau Bovine colostrum mengandung berbagai growth factor dan immune factor, salah satunya secretory IgA (sIgA) yang dengan jumlah signifikan dapat menghalangi adhesi patogen ke membrane mukosa dan menghambat kolonisasi sehingga bermanfaat untuk mengobati penyakit di saluran pencernaan. Penelitian yang telah dilakukan di Indonesia belum banyak membahas secara spesifik hubungan sIgA yang didapatkan dari kolostrum susu sapi sebagai terapi tambahan diare akut pada anak. Tujuan. Mengetahui pengaruh pemberian kolostrum susu sapi terhadap durasi diare akut dehidrasi ringan sedang dan kadar sekretori IgA pada anakMetode. Penelitian eksperimental yang dilaksanakan di Puskesmas dan Rumah Sakit di kota Padang. Penelitian dimulai dari bulan februari tahun 2022 sampai November 2022. Data terkumpul 30 sampel masing-masing pada kelompok kontrol yang mendapatkan terapi standar WHO dan kelompok intervensi yang mendapatkan terapi standar who ditambah kolostrum susu sapi. Dilakukan pengamatan terhadap durasi diare akut serta pemeriksaan terhadap kadar sIgA.Hasil. Terjadi pemendekan durasi diare secara signifikan antara kelompok intervensi dan kelompok kontrol sebesar 11,93 jam (p=0,021). Terdapat perbedaan kadar sIgA yang signifikan antara sebelum dan sesudah pemberian kolostrum susu sapi pada kelompok intervensi (p=0,003).Kesimpulan. Pemberian kolostrum susu sapi dapat memperpendek rerata durasi diare akut dan meningkatkan rerata kadar sIgA secara bermakna. Pemberian kolostrum susu sapi ini dapat disarankan sebagai terapi adjuvan dalam tatalaksana diare akut pada anak.

Development and modification Sobel edge detection in tuberculosis X-ray images Devita, Retno; Fitri, Iskandar; Yuhandri, Yuhandri; Yani, Finny Fitry
Indonesian Journal of Electrical Engineering and Computer Science Vol 35, No 2: August 2024
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijeecs.v35.i2.pp1191-1200

Tuberculosis (TB), a major global health threat caused by mycobacterium tuberculosis, claims lives across all age groups, underscoring the urgent need for accurate diagnostic methods. Traditional TB diagnosis using X-ray images faces challenges in detection accuracy, highlighting a critical problem in medical imaging. Addressing this, our study investigates the use of image processing techniques-specifically, a dataset of 112 TB X-ray images-employing pre-processing, segmentation, edge detection, and feature extraction methods. Central to our method is the adoption of a modified Sobel edge detection technique, named modification and extended magnitude gradient (MEMG), designed to enhance TB identification from X-ray images. The effectiveness of MEMG is rigorously evaluated against the gray-level co-occurrence matrix (GLCM) parameters, contrast, and correlation, where it demonstrably surpasses the standard Sobel detection, amplifying the contrast value by over 50% and achieving a correlation value nearing 1. Consequently, the MEMG method significantly improves the clarity and detail of TB-related anomalies in X-ray images, facilitating more precise TB detection. This study concludes that leveraging the MEMG technique in TB diagnosis presents a substantial advancement over conventional methods, promising a more reliable tool for combating this global health menace.

Peran Heparan Sulfate, Chondroitin Sulfate, dan Hyaluronic Acid Sebagai Biomarker Diagnosis Sepsis Neonatus Aswati, Lydia; Yusrawati, Yusrawati; Yani, Finny Fitry; Ali, Hirowati
Sari Pediatri Vol 26, No 4 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.4.2024.257-62

Sepsis neonatus menyebabkan morbiditas dan mortalitas yang bermakna. Berdasarkan penelitian pada populasi di dua dekade terakhir, diperkirakan insiden sepsis neonatus secara global adalah 2202 per 100.000 kelahiran hidup, dengan mortalitas antara 11-19%. Kultur darah masih menjadi gold standar untuk konfirmasi diagnosis sepsis neonatus, tetapi masih terbatas untuk mendapatkan hasilnya, diperlukan waktu sekitar 24-72 jam. Sepsis berhubungan dengan disfungsi sel endotel yang berat. Disfungsi endotel dapat disebabkan oleh oksidan, hiperglikemia, ROS, endotoksin bakteri serta sepsis. Disfungsi endotel pada sepsis neonatus terjadi penumpahan dari bahan-bahan yang menyusun lapisan glikokaliks endotel. Lapisannya disusun oleh proteoglikan, glikoprotein dan glikosaminoglikan. Komponen glikokaliks yang berada di sirkulasi seperti syndecan-1, hyaluronan, heparan sulfate dan chondroitin sulfate dapat ditemukan di plasma/serum dan urin, diharapkan dapat digunakan sebagai biomarker diagnosis sepsis neonatus.

Determinant of Neonatal Visit Coverage Rate in Serdang Bedagai Regency North Sumatra Indonesia Br Ginting Munthe, Novita; Machmud, Rizanda; Semiarty, Rima; Serudji, Joserizal; Bachtiar, Adang; Fitry Yani, Finny; Symond, Denas; Nelwati, Nelwati
Jurnal Ilmu Kesehatan Masyarakat Vol. 15 No. 3 (2024): Jurnal Ilmu Kesehatan Masyarakat (JIKM)
Publisher : Association of Public Health Scholars based in Faculty of Public Health, Sriwijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26553/jikm.2024.15.3.401-413

Neonatal mortality is a leading cause of infant deaths, particularly in developing countries. In Serdang Bedagai Regency, the coverage of neonatal visits remains low, contributing to the high neonatal mortality rate and causing economic losses. This study aims to identify factors related to the neonatal visit coverage rate in Serdang Bedagai Regency, North Sumatra, Indonesia. This study used a cross-sectional design with multivariate analysis. Data were collected from 200 mothers with babies aged 0-28 days in five health centers in Serdang Bedagai Regency. The variables analyzed include age, education, economic status, knowledge, maternal attitudes, culture, family support, midwife attitudes, access to health facilities, and service quality. The data were analyzed using logistic regression. The results showed that the variables consistently and significantly affecting the increase in neonatal visit coverage were maternal education, knowledge about neonatal visits, local culture, husband/family support, and the quality of visit services. Factors that significantly contributed to increasing coverage of neonatal visits were maternal education (p-value = 0.004, OR = 14.285), maternal knowledge (p-value = 0.000, OR= 75.920), local culture (p-value = 0.000, OR = 57.105), husband/family support (p-value = 0.000, OR = 77.763), and service quality (p-value = 0.000, OR = 47.474). These factors have a major influence in supporting the success of the neonatal visit program, with maternal knowledge and family support being the most dominant factors.. Efforts to increase coverage should involve educating mothers, involving families, and enhancing services while considering local wisdom.

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